Searching for up to 100 curated homologs for WP_012408052.1 NCBI__GCF_000020025.1:WP_012408052.1 (426 a.a.)
Found high-coverage hits (≥70%) to 74 curated proteins.
Removed hits that are identical to the query, leaving 73
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q8YMB5 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Nostoc sp. (see paper)
86% identity, 100% coverage of query (772 bits)
Q3MAV9 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Nostoc sp. (see paper)
85% identity, 100% coverage of query (771 bits)
K9PSG5 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Calothrix sp. (see paper)
84% identity, 100% coverage of query (754 bits)
C9EGX2 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Rahnella aquatilis (see paper)
45% identity, 96% coverage of query (332 bits)
AroA / b0908 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
aroA / P0A6D3 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Escherichia coli (strain K12) (see 14 papers)
AROA_ECOLI / P0A6D3 3-phosphoshikimate 1-carboxyvinyltransferase; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; EC 2.5.1.19 from Escherichia coli (strain K12) (see 9 papers)
P0A6D3 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Escherichia coli (see 12 papers)
2aa9A / P0A6D3 Epsp synthase liganded with shikimate (see paper)
44% identity, 99% coverage of query (325 bits)
2pq9A E. Coli epsps liganded with (r)-difluoromethyl tetrahedral reaction intermediate analog
44% identity, 99% coverage of query (325 bits)
1x8tA Epsps liganded with the (r)-phosphonate analog of the tetrahedral reaction intermediate
44% identity, 99% coverage of query (325 bits)
1x8rA Epsps liganded with the (s)-phosphonate analog of the tetrahedral reaction intermediate
44% identity, 99% coverage of query (325 bits)
1g6tA Structure of epsp synthase liganded with shikimate-3-phosphate
44% identity, 99% coverage of query (325 bits)
1g6sA Structure of epsp synthase liganded with shikimate-3-phosphate and glyphosate
44% identity, 99% coverage of query (325 bits)
3fjzA E. Coli epsp synthase (t97i) liganded with s3p and glyphosate
44% identity, 99% coverage of query (322 bits)
AROA_KLEPN / P24497 3-phosphoshikimate 1-carboxyvinyltransferase; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; EC 2.5.1.19 from Klebsiella pneumoniae (see paper)
44% identity, 98% coverage of query (315 bits)
7tm5B / A0A0H3GV01 Crystal structure of shikimate-3-phosphate bound 3-phosphoshikimate 1- carboxyvinyltransferase from klebsiella pneumoniae
43% identity, 99% coverage of query (315 bits)
1q36A Epsp synthase (asp313ala) liganded with tetrahedral reaction intermediate
44% identity, 99% coverage of query (315 bits)
7tm6A Crystal structure of shikimate-3-phosphate and glyphosate bound 3- phosphoshikimate 1-carboxyvinyltransferase from klebsiella pneumoniae
43% identity, 96% coverage of query (314 bits)
Q482G5 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Colwellia psychrerythraea (see paper)
42% identity, 96% coverage of query (308 bits)
AROA_VIBCH / Q9KRB0 3-phosphoshikimate 1-carboxyvinyltransferase; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; EC 2.5.1.19 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q9KRB0 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Vibrio cholerae serotype O1 (see paper)
3nvsA / Q9KRB0 1.02 angstrom resolution crystal structure of 3-phosphoshikimate 1- carboxyvinyltransferase from vibrio cholerae in complex with shikimate-3-phosphate (partially photolyzed) and glyphosate
42% identity, 96% coverage of query (299 bits)
epsps-S / CAD01096.1 5-enolpyruvylshikimate-3-phosphate synthase, partial from Eleusine indica (see paper)
43% identity, 96% coverage of query (294 bits)
A2T9R8 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Dunaliella salina (see paper)
42% identity, 98% coverage of query (294 bits)
Q93VK6 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Oryza sativa (see paper)
43% identity, 96% coverage of query (293 bits)
epsps-R / CAD01095.1 5-enolpyruvylshikimate-3-phosphate synthase, partial from Eleusine indica (see paper)
43% identity, 96% coverage of query (291 bits)
7m0oA / B5HND8 Dgt-28 epsps (see paper)
44% identity, 95% coverage of query (289 bits)
AROA_PETHY / P11043 3-phosphoshikimate 1-carboxyvinyltransferase, chloroplastic; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EC 2.5.1.19 from Petunia hybrida (Petunia) (see 5 papers)
41% identity, 96% coverage of query (286 bits)
A3TGI7 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Janibacter sp. (see paper)
40% identity, 98% coverage of query (256 bits)
A0A2K1XRJ2 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Populus trichocarpa (see paper)
42% identity, 85% coverage of query (235 bits)
ARO1_EMENI / P07547 Pentafunctional AROM polypeptide; EC 4.2.3.4; EC 2.5.1.19; EC 2.7.1.71; EC 4.2.1.10; EC 1.1.1.25 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
P07547 shikimate dehydrogenase (NADP+) (EC 1.1.1.25) from Aspergillus nidulans (see paper)
aromA pentafunctional AROM polypeptide; EC 1.1.1.25; EC 2.5.1.19; EC 2.7.1.71; EC 4.2.1.10; EC 4.2.3.4 from Emericella nidulans (see 4 papers)
34% identity, 99% coverage of query (224 bits)
2o0bA / P9WPY5 Mycobacterium tuberculosis epsp synthase in complex with s3p (partially photolyzed)
35% identity, 100% coverage of query (216 bits)
2o0zA Mycobacterium tuberculosis epsp synthase in complex with product (eps)
35% identity, 100% coverage of query (216 bits)
2o0xA Mycobacterium tuberculosis epsp synthase in complex with intermediate
35% identity, 100% coverage of query (216 bits)
2o0eA Mycobacterium tuberculosis epsp synthase in complex with s3p and pep
35% identity, 100% coverage of query (216 bits)
AROA_MYCTU / P9WPY5 3-phosphoshikimate 1-carboxyvinyltransferase; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; EC 2.5.1.19 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WPY5 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Mycobacterium tuberculosis (see paper)
35% identity, 100% coverage of query (215 bits)
6hqvA / G0S061 Pentafunctional arom complex from chaetomium thermophilum (see paper)
35% identity, 98% coverage of query (214 bits)
ARO1 / P08566 pentafunctional AROM polypeptide (EC 4.2.3.4; EC 1.1.1.25; EC 2.7.1.71; EC 2.5.1.19; EC 4.2.1.10) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
ARO1_YEAST / P08566 Pentafunctional AROM polypeptide; EC 4.2.3.4; EC 2.5.1.19; EC 2.7.1.71; EC 4.2.1.10; EC 1.1.1.25 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
33% identity, 98% coverage of query (212 bits)
7tbuA / Q5AME2 Crystal structure of the 5-enolpyruvate-shikimate-3-phosphate synthase (epsps) domain of aro1 from candida albicans in complex with shikimate-3-phosphate (see paper)
33% identity, 96% coverage of query (209 bits)
aroA / AAA21937.1 3-phosphoshikimate-1-carboxyvinyltransferase, partial from Aeromonas salmonicida (see paper)
36% identity, 98% coverage of query (203 bits)
A1Z0H6 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Pseudomonas fluorescens (see paper)
35% identity, 98% coverage of query (194 bits)
B8CWX4 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Halothermothrix orenii (see paper)
30% identity, 98% coverage of query (156 bits)
Build an alignment for WP_012408052.1 and 37 homologs with ≥ 30% identity
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K9VBD9 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Oscillatoria sp. (see paper)
28% identity, 99% coverage of query (148 bits)
mycA4 / H9TE88 shimimate dehydratase/3,4-dihydroxycyclohexa-1,5-diene-1-carboxylate--CoA ligase from Streptomyces flaveolus (see 3 papers)
29% identity, 95% coverage of query (144 bits)
K9RIB8 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Rivularia sp. PCC 7116 (see paper)
27% identity, 94% coverage of query (139 bits)
K9TRT1 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Oscillatoria sp. (see paper)
27% identity, 100% coverage of query (137 bits)
A0A139XBW5 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Scytonema hofmannii (see paper)
26% identity, 99% coverage of query (136 bits)
3slhD / Q83E11 1.70 angstrom resolution structure of 3-phosphoshikimate 1- carboxyvinyltransferase (aroa) from coxiella burnetii in complex with shikimate-3-phosphate and glyphosate
28% identity, 98% coverage of query (135 bits)
AROA_COXBU / Q83E11 3-phosphoshikimate 1-carboxyvinyltransferase; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; EC 2.5.1.19 from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Q83E11 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Coxiella burnetii (see paper)
28% identity, 98% coverage of query (134 bits)
K9QNN0 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Nostoc sp. (see paper)
26% identity, 98% coverage of query (134 bits)
A0A0D6KU47 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Tolypothrix sp. (see paper)
26% identity, 97% coverage of query (133 bits)
4egrA 2.50 angstrom resolution structure of 3-phosphoshikimate 1- carboxyvinyltransferase (aroa) from coxiella burnetii in complex with phosphoenolpyruvate
28% identity, 98% coverage of query (133 bits)
A0A0P4UM05 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Leptolyngbya boryana (see paper)
26% identity, 98% coverage of query (131 bits)
B4VHX1 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Coleofasciculus chthonoplastes (see paper)
26% identity, 96% coverage of query (127 bits)
K9TX81 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Chroococcidiopsis thermalis (see paper)
26% identity, 96% coverage of query (126 bits)
Q31RQ5 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Synechococcus elongatus (see paper)
Q5N2J9 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Synechococcus elongatus (see paper)
27% identity, 99% coverage of query (126 bits)
F5A7Q0 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Bacillus cereus (see paper)
26% identity, 98% coverage of query (125 bits)
aroA / CAH19218.1 3-phosphoshikimate 1-carboxyvinyltransferase from Pseudomonas putida (see paper)
28% identity, 97% coverage of query (124 bits)
A6TL04 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Alkaliphilus metalliredigens (see paper)
28% identity, 95% coverage of query (122 bits)
B1XM36 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Synechococcus sp. (see paper)
27% identity, 92% coverage of query (122 bits)
I4GHG6 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Microcystis aeruginosa (see paper)
26% identity, 96% coverage of query (121 bits)
AROA1_HALH5 / Q9KCA6 3-phosphoshikimate 1-carboxyvinyltransferase 1; 5-enolpyruvylshikimate-3-phosphate synthase 1; EPSP synthase 1; EPSPS 1; EC 2.5.1.19 from Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans)
27% identity, 89% coverage of query (119 bits)
aroE / P20691 5-enolpyruvoylshikimate-3-phosphate synthase (EC 2.5.1.19) from Bacillus subtilis (strain 168) (see 3 papers)
25% identity, 96% coverage of query (110 bits)
aroA / AAA71897.1 3-phosphoshikimate-1-carboxyvinyltransferase from Staphylococcus aureus (see paper)
25% identity, 96% coverage of query (105 bits)
AROA_STRPN / Q9S400 3-phosphoshikimate 1-carboxyvinyltransferase; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; EC 2.5.1.19 from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) (see 2 papers)
Q9S400 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Streptococcus pneumoniae (see paper)
23% identity, 96% coverage of query (97.4 bits)
1rf4A / Q9S400 Structural studies of streptococcus pneumoniae epsp synthase, tetrahedral intermediate bound state (see paper)
23% identity, 96% coverage of query (95.1 bits)
1rf6A Structural studies of streptococcus pneumoniae epsp synthase in s3p- glp bound state
23% identity, 96% coverage of query (95.1 bits)
A6WUV8 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Brucella anthropi (see paper)
25% identity, 94% coverage of query (93.6 bits)
B4WHQ7 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Synechococcus sp. (see paper)
25% identity, 92% coverage of query (89.7 bits)
AROA_AGRSC / Q9R4E4 3-phosphoshikimate 1-carboxyvinyltransferase; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; CP4 EPSP synthase; EC 2.5.1.19 from Agrobacterium sp. (strain CP4) (see 2 papers)
Q9R4E4 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Agrobacterium sp. (see paper)
24% identity, 95% coverage of query (87.8 bits)
2gg6A / Q9R4E4 Cp4 epsp synthase liganded with s3p (see paper)
24% identity, 95% coverage of query (87.4 bits)
2pqcA Cp4 epsps liganded with (r)-phosphonate tetrahedral reaction intermediate analog
24% identity, 95% coverage of query (87.4 bits)
2pqbA Cp4 epsps liganded with (r)-difluoromethyl tetrahedral intermediate analog
24% identity, 95% coverage of query (87.4 bits)
2ggaA Cp4 epsp synthase liganded with s3p and glyphosate
24% identity, 95% coverage of query (87.4 bits)
C3MC80 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) from Sinorhizobium fredii (see paper)
24% identity, 95% coverage of query (84.7 bits)
3vcyA / B5F9P4 Structure of mura (udp-n-acetylglucosamine enolpyruvyl transferase), from vibrio fischeri in complex with substrate udp-n- acetylglucosamine and the drug fosfomycin. (see paper)
21% identity, 72% coverage of query (54.3 bits)
B5F9P4 UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) from Aliivibrio fischeri (see paper)
B6DVJ7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) from Aliivibrio fischeri (see paper)
21% identity, 72% coverage of query (50.4 bits)
B5F9P4 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT; EC 2.5.1.7 from Aliivibrio fischeri (strain MJ11) (Vibrio fischeri)
21% identity, 72% coverage of query (50.4 bits)
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Lawrence Berkeley National Laboratory