Searching for up to 100 curated homologs for WP_012411289.1 NCBI__GCF_000020025.1:WP_012411289.1 (211 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q5NMD4 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Zymomonas mobilis (see paper)
    45% identity, 95% coverage of query (153 bits)

At-HF / Q9SZ30 imidazole-glycerol-phosphate synthase (EC 4.3.2.10) from Arabidopsis thaliana (see paper)
Q9SZ30 imidazole glycerol-phosphate synthase (EC 4.3.2.10) from Arabidopsis thaliana (see paper)
    40% identity, 95% coverage of query (147 bits)

HSERO_RS20325 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Herbaspirillum seropedicae SmR1
    39% identity, 96% coverage of query (147 bits)

HIS5_THET8 / Q7SIC0 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
Q7SIC0 imidazole glycerol-phosphate synthase (subunit 2/2) (EC 4.3.2.10) from Thermus thermophilus (see paper)
    42% identity, 92% coverage of query (137 bits)

DvMF_2305 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Desulfovibrio vulgaris Miyazaki F
    38% identity, 97% coverage of query (136 bits)

DVU0285 IGP synthase, amidotransferase subunit (EC 4.3.2.10) from Desulfovibrio vulgaris Hildenborough JW710
    38% identity, 94% coverage of query (132 bits)

Q8ZY40 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Pyrobaculum aerophilum (see paper)
    36% identity, 95% coverage of query (130 bits)

HIS5_YEAST / P33734 Imidazole glycerol phosphate synthase hisHF; IGP synthase; IGPS; ImGP synthase; EC 4.3.2.10; EC 3.5.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P33734 imidazole glycerol-phosphate synthase (EC 4.3.2.10) from Saccharomyces cerevisiae (see 4 papers)
    35% identity, 100% coverage of query (130 bits)

1ox4B / P33734 Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase (see paper)
    35% identity, 100% coverage of query (130 bits)

1ox5A Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase
    35% identity, 100% coverage of query (130 bits)

HIS5_MYCBO / P59957 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
    40% identity, 94% coverage of query (129 bits)

A4WHA5 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Pyrobaculum arsenaticum (see paper)
    39% identity, 98% coverage of query (126 bits)

HisH / b2023 imidazole glycerol phosphate synthase subunit HisH (EC 4.3.2.10) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
hisH / P60595 imidazole glycerol phosphate synthase subunit HisH (EC 4.3.2.10) from Escherichia coli (strain K12) (see 5 papers)
HIS5_ECOLI / P60595 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Escherichia coli (strain K12) (see paper)
hisH / RF|NP_416527 IGP synthase glutamine amidotransferase subunit; EC 2.4.2.- from Escherichia coli K12 (see 7 papers)
    37% identity, 94% coverage of query (114 bits)

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Build an alignment for WP_012411289.1 and 13 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

hisH / Q9X0C8 imidazole-glycerol-phosphate synthase glutamine amidotransferase subunit (EC 4.3.2.10) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
HIS5_THEMA / Q9X0C8 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; TmHisH; EC 4.3.2.10; EC 3.5.1.2 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9X0C8 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Thermotoga maritima (see 5 papers)
    29% identity, 94% coverage of query (94.0 bits)

7ac8B / Q9X0C8 Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex. (see paper)
    28% identity, 94% coverage of query (90.1 bits)

Q5L3Y1 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) (subunit 1/2) (EC 4.3.3.6) from Geobacillus kaustophilus (see paper)
    23% identity, 93% coverage of query (50.4 bits)

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