Searching for up to 100 curated homologs for WP_012411511.1 NCBI__GCF_000020025.1:WP_012411511.1 (400 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

EEVS_STIAD / E3FKM2 2-epi-5-epi-valiolone synthase; EEVS; EC 4.2.3.152 from Stigmatella aurantiaca (strain DW4/3-1) (see paper)
    30% identity, 92% coverage of query (167 bits)

valA / H2K887 2-epi-5-epi-valiolone synthase (EC 4.2.3.152) from Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) (see 3 papers)
VALA_STRHJ / H2K887 2-epi-5-epi-valiolone synthase; EEVS; Sedoheptulose 7-phosphate cyclase; EC 4.2.3.152 from Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) (see 2 papers)
H2K887 2-epi-5-epi-valiolone synthase (EC 4.2.3.152) from Streptomyces hygroscopicus (see paper)
valA / AAW88569.1 ValA from Streptomyces hygroscopicus subsp. jinggangensis (see paper)
valA / ABA41506.1 2-epi-5-epi-valiolone synthase from Streptomyces hygroscopicus subsp. jinggangensis (see paper)
    31% identity, 95% coverage of query (144 bits)

EEVS_STRGA / B0B0T7 2-epi-5-epi-valiolone synthase; EEVS; EC 4.2.3.152 from Streptomyces glaucescens (see paper)
    32% identity, 90% coverage of query (134 bits)

5eksA / V5V8R5 Structure of 3-dehydroquinate synthase from acinetobacter baumannii in complex with NAD
    31% identity, 80% coverage of query (134 bits)

CETA_ACTSX / A1YPR2 2-epi-5-epi-valiolone synthase; EEVS; EC 4.2.3.152 from Actinomyces sp. (see paper)
A1YPR2 2-epi-5-epi-valiolone synthase (EC 4.2.3.152) from Actinomyces sp. (see paper)
cetA / ABL74381.1 2-epi-5-epi-valiolone synthase from Actinomyces sp. Lu 9419 (see paper)
    30% identity, 91% coverage of query (132 bits)

6llaB Crystal structure of providencia alcalifaciens 3-dehydroquinate synthase (dhqs) in complex with mg2+ and NAD (see paper)
    32% identity, 79% coverage of query (132 bits)

6lk2A Crystal structure of providencia alcalifaciens 3-dehydroquinate synthase (dhqs) in complex with mg2+, NAD and chlorogenic acid
    31% identity, 79% coverage of query (131 bits)

ACBC_ACTS5 / Q9ZAE9 2-epi-5-epi-valiolone synthase; EEVS; C7-cyclitol synthase; Sedoheptulose 7-phosphate cyclase; EC 4.2.3.152 from Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110) (see paper)
Q9ZAE9 2-epi-5-epi-valiolone synthase (EC 4.2.3.152) from Actinoplanes sp. (see paper)
    30% identity, 93% coverage of query (127 bits)

acbC / CAA77208.2 2-epi-5-epi-valiolone synthase AcbC from Actinoplanes sp. SE50/110 (see 5 papers)
    30% identity, 88% coverage of query (125 bits)

SALQ_STRA4 / A8D7K2 2-epi-5-epi-valiolone synthase; EEVS; EC 4.2.3.152 from Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858) (see paper)
A8D7K2 2-epi-5-epi-valiolone synthase (EC 4.2.3.152) from Streptomyces albus (see paper)
    31% identity, 76% coverage of query (121 bits)

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Additional hits (identity < 30%)

ARO1 / P08566 pentafunctional AROM polypeptide (EC 4.2.3.4; EC 1.1.1.25; EC 2.7.1.71; EC 2.5.1.19; EC 4.2.1.10) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
ARO1_YEAST / P08566 Pentafunctional AROM polypeptide; EC 4.2.3.4; EC 2.5.1.19; EC 2.7.1.71; EC 4.2.1.10; EC 1.1.1.25 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    28% identity, 71% coverage of query (116 bits)

DDGS_TRIV2 / Q3M6C3 Demethyl-4-deoxygadusol synthase; DDGS; EC 4.2.3.154 from Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis) (see 2 papers)
Q3M6C3 demethyl-4-deoxygadusol synthase (EC 4.2.3.154) from Trichormus variabilis (see paper)
    27% identity, 90% coverage of query (111 bits)

5tprA / Q3M6C3 Desmethyl-4-deoxygadusol synthase from anabaena variabilis (ava_3858) with NAD+ and zn2+ bound (see paper)
    27% identity, 90% coverage of query (111 bits)

kanC / Q6L738 2-deoxy-scyllo-inosose synthase (EC 4.2.3.124) from Streptomyces kanamyceticus (see 2 papers)
DOIS_STRKN / Q6L738 2-deoxy-scyllo-inosose synthase; DOI synthase; DOIS; EC 4.2.3.124 from Streptomyces kanamyceticus (see paper)
kanA / CAE46939.1 2-deoxy-scyllo-inosose synthase from Streptomyces kanamyceticus (see paper)
    30% identity, 74% coverage of query (107 bits)

eevs / E7EXW6 2-epi-5-epi-valiolone synthase (EC 4.2.3.152) from Danio rerio (see paper)
    30% identity, 71% coverage of query (105 bits)

2gruB Crystal structure of 2-deoxy-scyllo-inosose synthase complexed with carbaglucose-6-phosphate, NAD+ and co2+
    26% identity, 74% coverage of query (105 bits)

btrC / Q9S5E2 2-deoxy-scyllo-inosose synthase (EC 4.2.3.124) from Niallia circulans (see 9 papers)
DOIS_NIACI / Q9S5E2 2-deoxy-scyllo-inosose synthase; DOI synthase; DOIS; EC 4.2.3.124 from Niallia circulans (Bacillus circulans) (see 5 papers)
Q9S5E2 2-deoxy-scyllo-inosose synthase (EC 4.2.3.124) from Niallia circulans (see 14 papers)
    26% identity, 74% coverage of query (104 bits)

2gruA / Q9S5E2 Crystal structure of 2-deoxy-scyllo-inosose synthase complexed with carbaglucose-6-phosphate, NAD+ and co2+ (see paper)
    26% identity, 74% coverage of query (104 bits)

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