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Searching for up to 100 curated homologs for WP_012469705.1 NCBI__GCF_000020385.1:WP_012469705.1 (95 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5j6fA / L8A208 Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
    32% identity, 85% coverage of query (52.0 bits)

CMPDT_STUST / P27603 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Stutzerimonas stutzeri (Pseudomonas stutzeri) (see paper)
    35% identity, 82% coverage of query (50.1 bits)

PheA / b2599 fused chorismate mutase/prephenate dehydratase (EC 5.4.99.5; EC 4.2.1.51) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pheA / P0A9J8 fused chorismate mutase/prephenate dehydratase (EC 5.4.99.5; EC 4.2.1.51) from Escherichia coli (strain K12) (see 16 papers)
CMPDT_ECOLI / P0A9J8 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Escherichia coli (strain K12) (see paper)
CH_024084 P-protein; EC 4.2.1.51; EC 5.4.99.5 from Escherichia coli K12 (see paper)
    36% identity, 87% coverage of query (47.8 bits)

C7EXK8 prephenate dehydratase (EC 4.2.1.51); chorismate mutase (EC 5.4.99.5) from Escherichia coli (see 2 papers)
    36% identity, 87% coverage of query (47.8 bits)

CHMU_METJA / Q57696 Chorismate mutase; CM; Monofunctional chorismate mutase AroQ(f); EC 5.4.99.5 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    31% identity, 84% coverage of query (47.0 bits)

Build an alignment

Build an alignment for WP_012469705.1 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

5gmuB / P39912 Crystal structure of chorismate mutase like domain of bifunctional dahp synthase of bacillus subtilis in complex with chlorogenic acid (see paper)
    29% identity, 74% coverage of query (45.1 bits)

1ecmB / P0A9J8 Atomic structure of the buried catalytic pocket of escherichia coli chorismate mutase
    35% identity, 88% coverage of query (43.9 bits)

P39912 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54); chorismate mutase (EC 5.4.99.5) from Bacillus subtilis (see paper)
    27% identity, 81% coverage of query (43.5 bits)

P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168)
    27% identity, 81% coverage of query (43.5 bits)

3nvtA / Q8Y6T2 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
    30% identity, 83% coverage of query (42.4 bits)

2gtvX / Q57696 Nmr structure of monomeric chorismate mutase from methanococcus jannaschii (see paper)
    29% identity, 84% coverage of query (42.4 bits)

3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate
    30% identity, 81% coverage of query (40.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory