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Searching for up to 100 curated homologs for WP_012469812.1 NCBI__GCF_000020385.1:WP_012469812.1 (781 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q8R7R4 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
    44% identity, 72% coverage of query (463 bits)

ptsI / AAA86049.1 PTS enzyme I from Geobacillus stearothermophilus (see paper)
    41% identity, 73% coverage of query (426 bits)

2hwgA / P08839 Structure of phosphorylated enzyme i of the phosphoenolpyruvate:sugar phosphotransferase system (see paper)
    40% identity, 70% coverage of query (412 bits)

Ctr / b2416 PTS enzyme I (EC 2.7.3.9) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ptsI / P08839 PTS enzyme I (EC 2.7.3.9) from Escherichia coli (strain K12) (see 66 papers)
PT1_ECOLI / P08839 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Escherichia coli (strain K12) (see 3 papers)
P08839 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Escherichia coli (see 4 papers)
ptsI / GB|AAC75469.1 phosphoenolpyruvate-protein phosphotransferase; EC 2.7.3.9 from Escherichia coli K12 (see 14 papers)
    40% identity, 70% coverage of query (412 bits)

P0A249 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    40% identity, 70% coverage of query (412 bits)

PtsP / b2829 phosphoenolpyruvate-protein phosphotransferase PtsP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
PtsP / P37177 phosphoenolpyruvate-protein phosphotransferase PtsP from Escherichia coli (strain K12) (see 6 papers)
PT1P_ECOLI / P37177 Phosphoenolpyruvate-dependent phosphotransferase system; Enzyme I-Ntr; EINtr; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Escherichia coli (strain K12) (see 2 papers)
    33% identity, 98% coverage of query (401 bits)

PT1_BACSU / P08838 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Bacillus subtilis (strain 168) (see paper)
P08838 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Bacillus subtilis (see paper)
    38% identity, 72% coverage of query (398 bits)

PT1_LYSSH / Q84F83 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Lysinibacillus sphaericus (Bacillus sphaericus) (see paper)
    39% identity, 71% coverage of query (392 bits)

PT1_LACLC / Q9ZAD8 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Lactococcus lactis subsp. cremoris (Streptococcus cremoris) (see paper)
    38% identity, 71% coverage of query (386 bits)

PT1_MYCCT / P45617 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154) (see paper)
    37% identity, 71% coverage of query (358 bits)

Psest_3355 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components from Pseudomonas stutzeri RCH2
    37% identity, 72% coverage of query (339 bits)

PT1_HALVD / D4GYE2 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    38% identity, 72% coverage of query (334 bits)

BPHYT_RS02740 N-acetylglucosamine-specific PTS system, I, HPr, and IIA components (nagF) from Burkholderia phytofirmans PsJN
    36% identity, 75% coverage of query (334 bits)

AO356_07335 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components from Pseudomonas fluorescens FW300-N2C3
    35% identity, 73% coverage of query (327 bits)

PS417_23035 D-trehalose PTS system, I, HPr, and IIA components from Pseudomonas simiae WCS417
    35% identity, 73% coverage of query (327 bits)

PTFAX_XANCP / P45597 Multiphosphoryl transfer protein; MTP; Triphosphoryl transfer protein; TTP; EC 2.7.3.9 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
    36% identity, 73% coverage of query (323 bits)

AO353_15995 trehalose-specific PTS system, I, HPr, and IIA components from Pseudomonas fluorescens FW300-N2E3
    34% identity, 73% coverage of query (321 bits)

TC 4.A.2.1.17 / Q9HY55 Phosphotransferase system transporter enzyme I, FruI, component of Fructose-specific PTS permease, FruIIBC/FruI-HPr-IIA from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    35% identity, 71% coverage of query (319 bits)

AO353_05485 Fructose-specific PTS system, I, HPr, and IIA components from Pseudomonas fluorescens FW300-N2E3
    35% identity, 71% coverage of query (317 bits)

AZOBR_RS32325 Fructose PTS system (E-I, HPr, and E-IIA components) from Azospirillum brasilense Sp245
    36% identity, 72% coverage of query (312 bits)

TC 4.A.1.1.15 / Q9HXN5 N-Acetyl-D-Glucosamine phosphotransferase system transporter, component of N-acetyl glucosamine-specific PTS permease, GlcNAc IIBC/GlcNAc I-HPr-IIA from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    34% identity, 71% coverage of query (300 bits)

AO353_04460 N-acetylglucosamine-specific PTS system, I, HPr, and IIA components (nagF) from Pseudomonas fluorescens FW300-N2E3
    32% identity, 71% coverage of query (296 bits)

AO356_17540 N-acetylglucosamine-specific PTS system, I, HPr, and IIA components (nagF) from Pseudomonas fluorescens FW300-N2C3
    32% identity, 73% coverage of query (289 bits)

Build an alignment

Build an alignment for WP_012469812.1 and 23 homologs with ≥ 30% identity

Select sequences

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory