Searching for up to 100 curated homologs for WP_012470203.1 NCBI__GCF_000020385.1:WP_012470203.1 (288 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4wjiA / Q92MG1 Crystal structure of cyclohexadienyl dehydrogenase from sinorhizobium meliloti in complex with NADP and tyrosine
    43% identity, 98% coverage of query (234 bits)

3gggD / O67636 The crystal structure of a. Aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+ (see paper)
    41% identity, 96% coverage of query (228 bits)

O67636 prephenate dehydrogenase (EC 1.3.1.12) from Aquifex aeolicus (see paper)
    41% identity, 96% coverage of query (228 bits)

3ggoA Crystal structure of prephenate dehydrogenase from a. Aeolicus with hpp and nadh
    41% identity, 96% coverage of query (228 bits)

3ggpA Crystal structure of prephenate dehydrogenase from a. Aeolicus in complex with hydroxyphenyl propionate and NAD+
    41% identity, 96% coverage of query (228 bits)

TYRC_ZYMMO / Q04983 Cyclohexadienyl dehydrogenase; Arogenate dehydrogenase; ADH; Prephenate dehydrogenase; PDH; EC 1.3.1.43; EC 1.3.1.12 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
    40% identity, 97% coverage of query (197 bits)

Q81P63 prephenate dehydrogenase (EC 1.3.1.12) from Bacillus anthracis (see paper)
    37% identity, 96% coverage of query (185 bits)

5uyyA / Q81P63 Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with l-tyrosine (see paper)
    37% identity, 96% coverage of query (185 bits)

6u60B Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with NAD and l-tyrosine
    37% identity, 96% coverage of query (185 bits)

J9XQS6 prephenate dehydrogenase (EC 1.3.1.12) from uncultured bacterium (see paper)
    39% identity, 83% coverage of query (177 bits)

Q8DUW0 prephenate dehydrogenase (EC 1.3.1.12) from Streptococcus mutans (see paper)
    31% identity, 96% coverage of query (155 bits)

3b1fA / Q8DUW0 Crystal structure of prephenate dehydrogenase from streptococcus mutans (see paper)
    30% identity, 98% coverage of query (146 bits)

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Build an alignment for WP_012470203.1 and 12 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

tyrAa / P73906 arogenate dehydrogenase monomer (EC 1.3.1.78) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
P73906 arogenate dehydrogenase (NADP+) (EC 1.3.1.78) from Synechocystis sp. PCC 6803 (see paper)
2f1kA / P73906 Crystal structure of synechocystis arogenate dehydrogenase (see paper)
    29% identity, 97% coverage of query (127 bits)

TYRA_MYCTU / O69721 Prephenate dehydrogenase; PDH; EC 1.3.1.12 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
    33% identity, 89% coverage of query (100 bits)

E1R5M5 arogenate dehydrogenase [NAD(P)+] (EC 1.3.1.79) from Sediminispirochaeta smaragdinae (see paper)
    25% identity, 91% coverage of query (61.2 bits)

A8AAX2 prephenate dehydrogenase (NADP+) (EC 1.3.1.13) from Ignicoccus hospitalis (see 2 papers)
    27% identity, 87% coverage of query (61.2 bits)

novF / Q9L9G2 prephenate dehydrogenase (EC 1.3.1.12) from Streptomyces niveus (see paper)
    27% identity, 93% coverage of query (60.1 bits)

TyrA / b2600 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
tyrA / P07023 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli (strain K12) (see 12 papers)
    26% identity, 77% coverage of query (53.5 bits)

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