Searching for up to 100 curated homologs for WP_012471101.1 NCBI__GCF_000020385.1:WP_012471101.1 (378 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
7d7oB / Q818A3 Crystal structure of cystathionine gamma-lyase from bacillus cereus atcc 14579 (see paper)
54% identity, 95% coverage of query (430 bits)
MCCB_BACSU / O05394 Cystathionine gamma-lyase; Gamma-cystathionase; Homocysteine gamma-lyase; EC 4.4.1.1; EC 4.4.1.2 from Bacillus subtilis (strain 168) (see paper)
O05394 cystathionine beta-synthase (O-acetyl-L-serine) (EC 2.5.1.134) from Bacillus subtilis (see paper)
52% identity, 100% coverage of query (422 bits)
METB_HELPX / Q1M0P5 Cystathionine gamma-synthase; CGS; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Helicobacter pylori (Campylobacter pylori) (see paper)
Q1M0P5 cystathionine gamma-synthase (EC 2.5.1.48) from Helicobacter pylori (see paper)
51% identity, 99% coverage of query (410 bits)
metB / P56069 cystathionine gamma-lyase (EC 4.4.1.1) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 2 papers)
51% identity, 99% coverage of query (409 bits)
A2RM21 cystathionine gamma-lyase (EC 4.4.1.1); cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Lactococcus lactis (see 2 papers)
metC / RF|YP_001033049.1 cystathionine beta-lyase; EC 4.4.1.8 from Lactococcus lactis subsp. cremoris MG1363 (see 3 papers)
50% identity, 99% coverage of query (404 bits)
4l0oH / P56069 Structure determination of cystathionine gamma-synthase from helicobacter pylori
50% identity, 99% coverage of query (401 bits)
GB|AAF14695.1 cystathionine beta-lyase; EC 4.4.1.8 from Austrochilidae (see paper)
50% identity, 99% coverage of query (395 bits)
METI_BACSU / O31631 Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase; CGS/OAH thiolyase; O-acetylhomoserine sulfhydrylase; OAH sulfhydrylase; EC 2.5.1.- from Bacillus subtilis (strain 168) (see paper)
51% identity, 99% coverage of query (390 bits)
6ldoA / F9UT53 Crystal structure of cystathionine gamma-lyase from lactobacillus plantarum complexed with l-serine (see paper)
49% identity, 99% coverage of query (389 bits)
6le4A Crystal structure of cystathionine gamma-lyase from lactobacillus plantarum complexed with cystathionine
49% identity, 99% coverage of query (389 bits)
B3TNN8 cystathionine gamma-lyase (subunit 2/2) (EC 4.4.1.1); cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Lacticaseibacillus casei (see paper)
48% identity, 99% coverage of query (383 bits)
B3TNN9 cystathionine gamma-lyase (subunit 1/2) (EC 4.4.1.1); cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Lacticaseibacillus casei (see paper)
47% identity, 100% coverage of query (380 bits)
uptH / AAK53484.1 cystathionine gamma-synthase from Xanthomonas campestris pv. campestris (see 4 papers)
52% identity, 100% coverage of query (378 bits)
4iyoB Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates
51% identity, 99% coverage of query (373 bits)
4iy7B Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates
51% identity, 99% coverage of query (373 bits)
4iy7A Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates
51% identity, 99% coverage of query (373 bits)
4ixzA Native structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae at ph 9.0
51% identity, 99% coverage of query (373 bits)
4iyoD / Q5H4T8 Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
51% identity, 99% coverage of query (372 bits)
Q5H4T8 cystathionine gamma-lyase (EC 4.4.1.1) from Xanthomonas oryzae pv. oryzae (see paper)
51% identity, 99% coverage of query (372 bits)
METC_COXBU / Q83A83 Cystathionine beta-lyase; CBL; Beta-cystathionase; Cysteine lyase; Cysteine-S-conjugate beta-lyase; EC 4.4.1.13 from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see paper)
49% identity, 99% coverage of query (370 bits)
CGL_MOUSE / Q8VCN5 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; EC 4.4.1.1; EC 4.4.1.2 from Mus musculus (Mouse) (see 6 papers)
47% identity, 100% coverage of query (368 bits)
7ba4A / A0A509J8D5 Structure of cystathionine gamma-lyase from pseudomonas aeruginosa
51% identity, 98% coverage of query (367 bits)
7mcbH / X5E0F1 Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme (see paper)
46% identity, 99% coverage of query (367 bits)
8j6nA / P18757 Crystal structure of cystathionine gamma-lyase in complex with compound 1 (see paper)
47% identity, 100% coverage of query (367 bits)
CGL_DICDI / Q55DV9 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; EC 4.4.1.1; EC 4.4.1.2 from Dictyostelium discoideum (Social amoeba) (see paper)
47% identity, 99% coverage of query (367 bits)
7mcyH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl3
46% identity, 99% coverage of query (367 bits)
7mcuH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl2
46% identity, 99% coverage of query (367 bits)
7mctH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl1
46% identity, 99% coverage of query (367 bits)
7mcqA Crystal structure of staphylococcus aureus cystathionine gamma lyase, aoaa-bound enzyme in dimeric form
46% identity, 99% coverage of query (367 bits)
Cth / P18757 cystathionine γ-lyase subunit (EC 4.4.1.1) from Rattus norvegicus (see 15 papers)
CGL_RAT / P18757 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; Probasin-related antigen; PRB-RA; EC 4.4.1.1; EC 4.4.1.2 from Rattus norvegicus (Rat) (see paper)
47% identity, 100% coverage of query (363 bits)
METC_BACSU / O31632 Cystathionine beta-lyase MetC; CBL; Beta-cystathionase MetC; Cysteine lyase MetC; Cysteine-S-conjugate beta-lyase MetC; EC 4.4.1.13 from Bacillus subtilis (strain 168) (see 2 papers)
45% identity, 99% coverage of query (362 bits)
6k1lA / B4SII9 E53a mutant of a putative cystathionine gamma-lyase (see paper)
49% identity, 100% coverage of query (358 bits)
6k1lB E53a mutant of a putative cystathionine gamma-lyase
49% identity, 100% coverage of query (358 bits)
8juiA / Q818J6 Crystal structures of cystathionine beta lyase from bacillus cereus atcc 14579
45% identity, 96% coverage of query (356 bits)
4ixsB Native structure of xometc at ph 5.2
50% identity, 99% coverage of query (356 bits)
6cjaA / Q5ZX43 Crystal structure of cystathionine beta-lyase from legionella pneumophila philadelphia 1 in complex with alanyl-plp and serine
49% identity, 98% coverage of query (353 bits)
CBL1 / P53780 cystathionine β-lyase monomer (EC 4.4.1.13) from Arabidopsis thaliana (see 3 papers)
METC_ARATH / P53780 Cystathionine beta-lyase, chloroplastic; CBL; Beta-cystathionase; Cysteine lyase; Cysteine-S-conjugate beta-lyase; EC 4.4.1.13 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
45% identity, 95% coverage of query (343 bits)
1ibjA / P53780 Crystal structure of cystathionine beta-lyase from arabidopsis thaliana (see paper)
45% identity, 95% coverage of query (341 bits)
CTH / P32929 cystathionine γ-lyase monomer (EC 4.4.1.1; EC 4.4.1.2; EC 4.2.1.22) from Homo sapiens (see 7 papers)
CGL_HUMAN / P32929 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; EC 4.4.1.1; EC 4.4.1.2 from Homo sapiens (Human) (see 10 papers)
P32929 cystathionine gamma-lyase (EC 4.4.1.1) from Homo sapiens (see 9 papers)
46% identity, 100% coverage of query (336 bits)
3cogD / P32929 Crystal structure of human cystathionase (cystathionine gamma lyase) in complex with dl-propargylglycine (see paper)
46% identity, 100% coverage of query (336 bits)
6nbaA Crystal structure of human cystathionine gamma lyase with s-3- carboxpropyl-l-cysteine
46% identity, 100% coverage of query (336 bits)
METB_MYCTU / P9WGB7 Cystathionine gamma-synthase; CGS; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
47% identity, 98% coverage of query (333 bits)
A0A0M3VI47 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Mimosa pudica (see paper)
44% identity, 94% coverage of query (328 bits)
5eigC Engineered human cystathionine gamma lyase (e59t, e339v) to deplet cysteine
46% identity, 100% coverage of query (325 bits)
5tsuC Active conformation for engineered human cystathionine gamma lyase (e59n, r119l, e339v) to depleting methionine
46% identity, 100% coverage of query (324 bits)
A0PKT3 cystathionine gamma-synthase (EC 2.5.1.48) from Mycobacterium ulcerans (see paper)
46% identity, 99% coverage of query (323 bits)
3qhxA / A0PKT3 Crystal structure of cystathionine gamma-synthase metb (cgs) from mycobacterium ulcerans agy99 bound to hepes (see paper)
46% identity, 99% coverage of query (322 bits)
5tsuA Active conformation for engineered human cystathionine gamma lyase (e59n, r119l, e339v) to depleting methionine
45% identity, 100% coverage of query (318 bits)
MEGL_FUSNP / Q8L0X4 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methionine-alpha-deamino-gamma-mercaptomethane-lyase; METase; EC 4.4.1.11; EC 4.4.1.2 from Fusobacterium nucleatum subsp. polymorphum (Fusobacterium polymorphum) (see paper)
45% identity, 95% coverage of query (316 bits)
MEGL_FUSNN / Q8RDT4 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-cysteine desulfidase; EC 4.4.1.11; EC 4.4.1.2; EC 4.4.1.28 from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) (see paper)
Q8RDT4 methionine gamma-lyase (EC 4.4.1.11) from Fusobacterium nucleatum subsp. nucleatum (see paper)
45% identity, 95% coverage of query (314 bits)
CBL_NEUCR / Q1K8G0 Cystathionine beta-lyase; Cysteine-S-conjugate beta-lyase; EC 4.4.1.13 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see paper)
Q1K8G0 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Neurospora crassa (see paper)
43% identity, 96% coverage of query (306 bits)
H7C6A2 cystathionine gamma-synthase (EC 2.5.1.48) from Corynebacterium glutamicum (see paper)
43% identity, 99% coverage of query (305 bits)
5x5hA / Q79VD9 Crystal structure of metb from corynebacterium glutamicum (see paper)
43% identity, 99% coverage of query (305 bits)
A0A1L7H888 methionine gamma-lyase (EC 4.4.1.11) from Clostridium tetani (see paper)
43% identity, 100% coverage of query (304 bits)
METC_STAHJ / Q4L332 Cystathionine beta-lyase MetC; CBL; Beta-cystathionase; Cysteine lyase; Cysteine-S-conjugate beta-lyase; EC 4.4.1.13 from Staphylococcus haemolyticus (strain JCSC1435) (see paper)
41% identity, 97% coverage of query (303 bits)
4omaA The crystal structure of methionine gamma-lyase from citrobacter freundii in complex with l-cycloserine pyridoxal-5'-phosphate
41% identity, 98% coverage of query (303 bits)
3jwbA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with norleucine
41% identity, 98% coverage of query (303 bits)
3jwaA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with methionine phosphinate
41% identity, 98% coverage of query (303 bits)
3jw9A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with s-ethyl-cysteine
41% identity, 98% coverage of query (303 bits)
5m3zA Crystal structure of citrobacter freundii methionine gamma-lyase with c115h replacement in the complex with l-norleucine
41% identity, 98% coverage of query (303 bits)
O15565 methionine gamma-lyase (EC 4.4.1.11) from Trichomonas vaginalis (see paper)
mgl2 / CAA04125.1 methionine gamma-lyase from Trichomonas vaginalis (see paper)
42% identity, 95% coverage of query (302 bits)
6egrA / A0A0A5P8W7 Crystal structure of citrobacter freundii methionine gamma-lyase with v358y replacement (see paper)
41% identity, 98% coverage of query (302 bits)
Q5MQ31 methionine gamma-lyase (EC 4.4.1.11) from Brevibacterium linens (see paper)
43% identity, 99% coverage of query (301 bits)
4hf8A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with glycine
41% identity, 98% coverage of query (301 bits)
SO1812 Methionine gamma-lyase (EC 4.4.1.11) from Shewanella oneidensis MR-1
44% identity, 98% coverage of query (300 bits)
Q84AR1 methionine gamma-lyase (EC 4.4.1.11); alliin lyase (EC 4.4.1.4) from Citrobacter freundii (see 11 papers)
41% identity, 98% coverage of query (298 bits)
6ld9A Crystal structure of cystathionine gamma synthase from xanthomonas oryzae pv. Oryzae in complex with cystathionine
43% identity, 99% coverage of query (295 bits)
CH_124009 cystathionine-gamma-lyase [Acremonium chrysogenum] from Magnaporthe grisea 70-15 (see 2 papers)
42% identity, 99% coverage of query (294 bits)
J7TA22 methionine gamma-lyase (EC 4.4.1.11) from Clostridium sporogenes (see 2 papers)
40% identity, 100% coverage of query (293 bits)
5dx5A Crystal structure of methionine gamma-lyase from clostridium sporogenes (see paper)
40% identity, 100% coverage of query (293 bits)
Q86D28 methionine gamma-lyase (EC 4.4.1.11) from Entamoeba histolytica (see 3 papers)
metg / BAC75877.2 methionine gamma-lyase from Entamoeba histolytica (see paper)
38% identity, 95% coverage of query (293 bits)
3mkjA Methionine gamma-lyase from citrobacter freundii with pyridoximine-5'- phosphate
41% identity, 98% coverage of query (293 bits)
8bizA Cystathionine gamma-lyase from toxoplasma gondii in complex with cysteine
41% identity, 98% coverage of query (293 bits)
B6K8Y1 cystathionine gamma-lyase (EC 4.4.1.1) from Toxoplasma gondii (see paper)
40% identity, 98% coverage of query (291 bits)
7nl1D / A0A125YN40 Crystal structure of cystathionine gamma-lyase from toxoplasma gondii (see paper)
40% identity, 98% coverage of query (291 bits)
3aejA / Q86D28 Reaction intermediate structure of entamoeba histolytica methionine gamma-lyase 1 tetramer containing michaelis complex and methionine- pyridoxal-5'-phosphate
38% identity, 95% coverage of query (291 bits)
6ld8A / Q5H1U9 Crystal structure of cystathionine gamma synthase from xanthomonas oryzae pv. Oryzae in complex with aminoacrylate and cysteine
43% identity, 99% coverage of query (291 bits)
8bisA Crystal structure of cystathionine gamma-lyase from toxoplasma gondii in complex with dl-propargylglycine
40% identity, 98% coverage of query (291 bits)
6lgoA Crystal structure of cystathionine gamma synthase from xanthomonas oryzae pv. Oryzae in complex with homolanthionine
43% identity, 99% coverage of query (291 bits)
3aeoA Reaction intermediate structure of entamoeba histolytica methionine gamma-lyase 1 containing methionine alpha, beta-enamine-pyridoxamine- 5'-phosphate
38% identity, 95% coverage of query (291 bits)
3aelA Reaction intermediate structure of entamoeba histolytica methionine gamma-lyase 1 containing methionine imine-pyridoxamine-5'-phosphate and alpha-amino-alpha, beta-butenoic acid-pyridoxal-5'-phosphate
38% identity, 95% coverage of query (291 bits)
3aejC Reaction intermediate structure of entamoeba histolytica methionine gamma-lyase 1 tetramer containing michaelis complex and methionine- pyridoxal-5'-phosphate
38% identity, 95% coverage of query (291 bits)
mdeA / P13254 MdeA from Pseudomonas putida (see 6 papers)
MEGL_PSEPU / P13254 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methioninase; EC 4.4.1.11; EC 4.4.1.2 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 5 papers)
1pg8A / P13254 Crystal structure of l-methionine alpha-, gamma-lyase
BAA13642.1 L-methionine gamma-lyase from Pseudomonas putida (see paper)
41% identity, 99% coverage of query (289 bits)
AB823649.2 / U6BYK3 mimosinase (EC 4.3.3.8) from Mimosa pudica (see 5 papers)
U6BYK3 mimosinase (EC 3.5.1.61) from Mimosa pudica (see paper)
36% identity, 99% coverage of query (289 bits)
megL / A0A0J6G7P5 methionine γ-lyase (EC 4.4.1.11) from Pseudomonas deceptionensis (see paper)
MEGL_PSEDM / A0A0J6G7P5 L-methionine gamma-lyase; MGL; EC 4.4.1.11 from Pseudomonas deceptionensis (see paper)
42% identity, 99% coverage of query (289 bits)
5x2xA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-homocysteine intermediates
41% identity, 99% coverage of query (289 bits)
5x2wA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-methionine intermediates
41% identity, 99% coverage of query (289 bits)
3vk3A Crystal structure of l-methionine gamma-lyase from pseudomonas putida c116h mutant complexed with l-methionine
41% identity, 99% coverage of query (289 bits)
5x30C Crystal structure of pseudomonas putida methionine gamma-lyase c116h mutant with l-homocysteine intermediates.
41% identity, 99% coverage of query (289 bits)
E9AFE7 cystathionine gamma-lyase (EC 4.4.1.1) from Leishmania major (see paper)
41% identity, 99% coverage of query (288 bits)
B2LXT6 cystathionine gamma-lyase (EC 4.4.1.1) from Aspergillus nidulans (see paper)
mecB cystathionine gamma-lyase; EC 4.4.1.1 from Emericella nidulans (see paper)
40% identity, 99% coverage of query (288 bits)
A8CEI3 mimosinase (EC 3.5.1.61) from Leucaena leucocephala (see 2 papers)
38% identity, 96% coverage of query (285 bits)
1e5eA / A2FEV4 Methionine gamma-lyase (mgl) from trichomonas vaginalis in complex with propargylglycine
40% identity, 95% coverage of query (285 bits)
1e5fA Methionine gamma-lyase (mgl) from trichomonas vaginalis
40% identity, 95% coverage of query (285 bits)
O15564 methionine gamma-lyase (EC 4.4.1.11) from Trichomonas vaginalis (see paper)
mgl1 / CAA04124.1 methionine gamma-lyase from Trichomonas vaginalis (see paper)
40% identity, 95% coverage of query (283 bits)
MetB / b3939 O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase (EC 2.5.1.48) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
metB / P00935 O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase (EC 2.5.1.48) from Escherichia coli (strain K12) (see 11 papers)
METB_ECOLI / P00935 Cystathionine gamma-synthase; CGS; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Escherichia coli (strain K12) (see 2 papers)
39% identity, 98% coverage of query (280 bits)
Q4WCI1 cystathionine gamma-lyase (EC 4.4.1.1) from Aspergillus fumigatus (see paper)
40% identity, 99% coverage of query (280 bits)
1cs1D / P00935 Cystathionine gamma-synthase (cgs) from escherichia coli (see paper)
39% identity, 98% coverage of query (280 bits)
8biuA Cystathionine gamma-lyase in complex with cystathionine
40% identity, 98% coverage of query (280 bits)
Q86D27 methionine gamma-lyase (EC 4.4.1.11) from Entamoeba histolytica (see 3 papers)
metg / BAC75878.2 methionine gamma-lyase 2 from Entamoeba histolytica (see paper)
38% identity, 99% coverage of query (278 bits)
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