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Searching for up to 100 curated homologs for WP_012505314.1 NCBI__GCF_000020625.1:WP_012505314.1 (357 a.a.)

Found high-coverage hits (≥70%) to 74 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

METXA_TRIV2 / Q3M5Q6 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis) (see paper)
    57% identity, 98% coverage of query (417 bits)

METXA_SALRD / Q2S5A6 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Salinibacter ruber (strain DSM 13855 / M31) (see paper)
    49% identity, 93% coverage of query (336 bits)

METXA_DEFDS / D3P9D1 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Deferribacter desulfuricans (strain DSM 14783 / JCM 11476 / NBRC 101012 / SSM1) (see paper)
    42% identity, 95% coverage of query (301 bits)

METXA_METPE / B8GHE0 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) (see paper)
    45% identity, 94% coverage of query (291 bits)

METXA_METVS / A6UNL1 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) (see paper)
    43% identity, 93% coverage of query (291 bits)

METXA_PSYTT / K4ICC9 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Psychroflexus torquis (strain ATCC 700755 / CIP 106069 / ACAM 623) (see paper)
    40% identity, 94% coverage of query (289 bits)

METXA_METFP / K2QXP6 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanobacterium formicicum (strain DSM 3637 / PP1) (see paper)
    42% identity, 92% coverage of query (286 bits)

METXA_METMS / D5E9R7 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP) (see paper)
    43% identity, 94% coverage of query (284 bits)

METXA_METZD / F7XKY8 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5) (Methanohalophilus zhilinae) (see paper)
    40% identity, 95% coverage of query (281 bits)

METXA_METEZ / D7E9E0 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303) (see paper)
    40% identity, 97% coverage of query (281 bits)

2vatA Crystal structure of deacetylcephalosporin c acetyltransferase in complex with coenzyme a
    45% identity, 92% coverage of query (281 bits)

METXA_METST / Q2NGH9 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3) (see paper)
    41% identity, 97% coverage of query (280 bits)

2vavB / P39058 Crystal structure of deacetylcephalosporin c acetyltransferase (dac- soak) (see paper)
    45% identity, 92% coverage of query (278 bits)

METXA_METRM / D3E3E4 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1) (Methanobacterium ruminantium) (see paper)
    41% identity, 94% coverage of query (275 bits)

METXA_METBU / Q12XS2 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) (see paper)
    41% identity, 94% coverage of query (272 bits)

METXA_HAEIN / P45131 Homoserine O-acetyltransferase; HAT; Homoserine O-trans-acetylase; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
P45131 homoserine O-acetyltransferase (EC 2.3.1.31) from Haemophilus influenzae (see paper)
    41% identity, 94% coverage of query (270 bits)

metX / O68640 homoserine O-acetyltransferase (EC 2.3.1.31) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
METXA_CORGL / O68640 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 2 papers)
    42% identity, 92% coverage of query (269 bits)

METXA_THET2 / Q9RA51 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
    43% identity, 95% coverage of query (269 bits)

FUB5_GIBF5 / S0DUX2 Homoserine O-acetyltransferase FUB5; Fusaric acid biosynthesis protein 5; EC 2.3.1.31 from Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi) (see 9 papers)
    40% identity, 96% coverage of query (268 bits)

CEFG / P39058 deacetylcephalosporin C acetyltransferase (EC 2.3.1.175) from Hapsidospora chrysogena (see 5 papers)
CEFG_HAPCH / P39058 Acetyl-CoA--deacetylcephalosporin C acetyltransferase; DAC acetyltransferase; DAC-AT; DCPC-ATF; EC 2.3.1.175 from Hapsidospora chrysogena (Acremonium chrysogenum) (see paper)
P39058 deacetylcephalosporin-C acetyltransferase (EC 2.3.1.175) from Acremonium chrysogenum (see paper)
    42% identity, 92% coverage of query (268 bits)

FUB5_GIBM7 / W7N293 Homoserine O-acetyltransferase FUB5; Fusaric acid biosynthesis protein 5; EC 2.3.1.31 from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) (see 10 papers)
    42% identity, 88% coverage of query (268 bits)

METXA_LEPIN / Q8F4I0 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) (see 2 papers)
    41% identity, 93% coverage of query (266 bits)

METXA_CAUVC / Q9AAS1 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus) (see paper)
    42% identity, 97% coverage of query (265 bits)

METXA_TRIL1 / B3E278 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) (Geobacter lovleyi) (see paper)
    41% identity, 92% coverage of query (261 bits)

metX / P94891 homoserine O-acetyltransferase (EC 2.3.1.31) from Leptospira meyeri (see paper)
P94891 homoserine O-acetyltransferase (EC 2.3.1.31) from Leptospira meyeri (see paper)
metX / GB|CAA71733.1 homoserine O-acetyltransferase; EC 2.3.1.31 from Leptospira meyeri (see paper)
    40% identity, 92% coverage of query (261 bits)

METXA_SOLM1 / C4XNQ9 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Solidesulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1) (Desulfovibrio magneticus) (see paper)
    41% identity, 92% coverage of query (258 bits)

METXA_METAC / Q8TME4 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
    36% identity, 92% coverage of query (255 bits)

5w8oB / K5B926 Homoserine transacetylase metx from mycobacterium hassiacum (see paper)
    43% identity, 92% coverage of query (255 bits)

METXA_CHLAA / A9WKM8 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
    41% identity, 93% coverage of query (254 bits)

METXS_BURTA / Q2T284 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CCUG 48851 / CIP 106301 / E264) (see paper)
    40% identity, 98% coverage of query (254 bits)

METXA_CYCMS / G0J5N4 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Cyclobacterium marinum (strain ATCC 25205 / DSM 745 / LMG 13164 / NCIMB 1802) (Flectobacillus marinus) (see paper)
    40% identity, 93% coverage of query (253 bits)

FUB5_FUSO4 / A0A0D2YG05 Homoserine O-acetyltransferase FUB5; Fusaric acid biosynthesis protein 5; EC 2.3.1.31 from Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) (Fusarium vascular wilt of tomato) (see 8 papers)
    40% identity, 87% coverage of query (251 bits)

K5B926 homoserine O-acetyltransferase (EC 2.3.1.31) from Mycolicibacterium hassiacum (see paper)
    42% identity, 92% coverage of query (250 bits)

METXA_METLZ / A2SQW3 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) (see paper)
    40% identity, 92% coverage of query (249 bits)

B1MG17 homoserine O-acetyltransferase (EC 2.3.1.31) from Mycobacteroides abscessus (see paper)
    40% identity, 93% coverage of query (248 bits)

METXS_HALAF / S2L5R8 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Halomonas anticariensis (strain DSM 16096 / CECT 5854 / LMG 22089 / FP35) (see paper)
    40% identity, 93% coverage of query (246 bits)

6iohA / A0QSZ0 Crystal structure of homoserine o-acetyltransferase in complex with homoserine from mycobacterium smegmatis atcc 19420 (see paper)
    42% identity, 92% coverage of query (245 bits)

6ioiA Crystal structure of homoserine o-acetyltransferase in complex with coa from mycobacterium smegmatis atcc 19420
    42% identity, 92% coverage of query (245 bits)

MTXAW_RHOBA / Q7UG04 Bifunctional methionine biosynthesis protein MetXA/MetW; EC 2.3.1.31 from Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) (see paper)
    41% identity, 89% coverage of query (243 bits)

METXA_SULAO / E0UR96 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Sulfurimonas autotrophica (strain ATCC BAA-671 / DSM 16294 / JCM 11897 / OK10) (see paper)
    37% identity, 91% coverage of query (242 bits)

METXS_BORPD / A9I0E6 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) (see paper)
    41% identity, 93% coverage of query (241 bits)

METXS_HALNC / D0L1T6 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus) (see paper)
    41% identity, 89% coverage of query (237 bits)

METXA_NATPD / Q3IUE8 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis) (see paper)
    39% identity, 91% coverage of query (237 bits)

METXS_NEIGO / A0A0I9QGZ7 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Neisseria gonorrhoeae (see paper)
    39% identity, 88% coverage of query (235 bits)

METXS_COMTK / B7X2B6 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Comamonas testosteroni (strain DSM 14576 / KF-1) (Pseudomonas testosteroni) (see paper)
    37% identity, 93% coverage of query (232 bits)

P9WJY9 homoserine O-acetyltransferase (EC 2.3.1.31) from Mycobacterium tuberculosis (see paper)
    39% identity, 91% coverage of query (230 bits)

7rytB / P9WJY9 Crystal structure of mycobacterium tuberculosis acetylated homoserine transacetylase with coenzyme a (see paper)
    39% identity, 91% coverage of query (230 bits)

6puxA Homoserine transacetylase metx from mycobacterium tuberculosis
    39% identity, 91% coverage of query (230 bits)

8f2lA Crystal structure of mycobacterium tuberculosis homoserine transacetylase in complex with l-homoserine
    39% identity, 91% coverage of query (230 bits)

METXA_HALGM / M0HG00 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haloferax gibbonsii (strain ATCC 33959 / DSM 4427 / JCM 8863 / NBRC 102184 / NCIMB 2188 / Ma 2.38) (see paper)
    39% identity, 93% coverage of query (228 bits)

METXS_PSEPK / Q88CT3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
    40% identity, 93% coverage of query (228 bits)

METXA_HALPT / M0GNC6 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haloferax prahovense (strain DSM 18310 / JCM 13924 / TL6) (see paper)
    39% identity, 93% coverage of query (227 bits)

METXA_HALVD / D4GY94 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    39% identity, 93% coverage of query (227 bits)

SST_SCHPO / Q10341 Serine O-succinyltransferase; SST; EC 2.3.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
cys2 homoserine O-acetyltransferase (predicted); EC 2.3.1.- from Schizosaccharomyces pombe (see 2 papers)
    38% identity, 87% coverage of query (225 bits)

METXS_ACIAD / Q6FEQ3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    39% identity, 93% coverage of query (224 bits)

METXA_NAUPA / B9L9I6 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH) (see paper)
    35% identity, 91% coverage of query (224 bits)

METXS_PSEAE / P57714 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
    39% identity, 89% coverage of query (223 bits)

SST_HALAF / S2KHP1 Serine O-succinyltransferase; SST; Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.-; EC 2.3.1.46 from Halomonas anticariensis (strain DSM 16096 / CECT 5854 / LMG 22089 / FP35) (see paper)
    37% identity, 92% coverage of query (223 bits)

cysA putative serine O-acetyltransferase from Emericella nidulans (see paper)
    41% identity, 74% coverage of query (223 bits)

SST_EMEND / A0A1D3PCM3 Serine O-succinyltransferase; SST; EC 2.3.1.- from Emericella nidulans (Aspergillus nidulans) (see paper)
    41% identity, 74% coverage of query (223 bits)

SST_EMENI / Q5AT15 Serine O-succinyltransferase; SST; EC 2.3.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
    41% identity, 74% coverage of query (222 bits)

METXS_PSEU2 / Q4ZZ78 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Pseudomonas syringae pv. syringae (strain B728a) (see paper)
    37% identity, 96% coverage of query (216 bits)

METXA_DEIGD / Q1J115 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Deinococcus geothermalis (strain DSM 11300 / AG-3a) (see paper)
    40% identity, 91% coverage of query (216 bits)

METXA_HALLT / B9LTF0 Homoserine O-acetyltransferase; HAT; Homoserine transacetylase; HTA; EC 2.3.1.31 from Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) (see paper)
    36% identity, 91% coverage of query (214 bits)

SST_STEMA / A0A0I9RJ56 Serine O-succinyltransferase; SST; Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.-; EC 2.3.1.46 from Stenotrophomonas maltophilia (Pseudomonas maltophilia) (Xanthomonas maltophilia) (see paper)
    38% identity, 96% coverage of query (212 bits)

I1R9N5 serine O-acetyltransferase (EC 2.3.1.30) from Fusarium graminearum (see paper)
    41% identity, 72% coverage of query (211 bits)

SST_FRAAD / H8L374 Serine O-succinyltransferase; SST; Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.-; EC 2.3.1.46 from Frateuria aurantia (strain ATCC 33424 / DSM 6220 / KCTC 2777 / LMG 1558 / NBRC 3245 / NCIMB 13370) (Acetobacter aurantius) (see paper)
    37% identity, 92% coverage of query (205 bits)

EFUC_HORCR / A0A2Z4HPY5 Acetyltransferase efuC; Enfumafungin biosynthesis cluster protein C; EC 2.3.1.- from Hormonema carpetanum (see paper)
    38% identity, 78% coverage of query (201 bits)

SST_XANCP / Q8P8L2 Serine O-succinyltransferase; SST; Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.-; EC 2.3.1.46 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
    35% identity, 95% coverage of query (197 bits)

dcsE / D2Z028 serine O-acetyltransferase (EC 2.3.1.30) from Streptomyces lavendulae (see paper)
DCSE_STRLA / D2Z028 L-serine/homoserine O-acetyltransferase; Homoserine O-trans-acetylase; EC 2.3.1.30; EC 2.3.1.31 from Streptomyces lavendulae (see 2 papers)
D2Z028 serine O-acetyltransferase (EC 2.3.1.30); homoserine O-acetyltransferase (EC 2.3.1.31) from Streptomyces lavendulae (see paper)
    35% identity, 98% coverage of query (185 bits)

Build an alignment

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Additional hits (identity < 30%)

CGHLE_CORGL / Q8NS43 Probable esterase Cgl0839; HAT-like esterase; cgHle; EC 3.1.1.- from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 2 papers)
    27% identity, 92% coverage of query (104 bits)

mekB / Q0MRG5 ethyl acetate hydrolase (EC 3.1.1.113) from Pseudomonas veronii (see paper)
MEKB_PSEVE / Q0MRG5 Ethyl acetate hydrolase; EC 3.1.1.113 from Pseudomonas veronii (see 2 papers)
Q0MRG5 ethyl acetate hydrolase (EC 3.1.1.113) from Pseudomonas veronii (see paper)
    28% identity, 92% coverage of query (97.8 bits)

METXS_BREDA / F4QV02 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Brevundimonas diminuta (strain ATCC 11568 / DSM 7234 / NBRC 12697 / NCIMB 9393 / NCTC 8545) (see paper)
    28% identity, 88% coverage of query (77.0 bits)

METXS_XANCP / Q8P6V8 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
    29% identity, 78% coverage of query (75.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory