Searching for up to 100 curated homologs for WP_012505623.1 NCBI__GCF_000020625.1:WP_012505623.1 (460 a.a.)
Found high-coverage hits (≥70%) to 50 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q8DVX5 argininosuccinate lyase (EC 4.3.2.1) from Streptococcus mutans (see paper)
48% identity, 99% coverage of query (453 bits)
ARLY_NOSP7 / Q9LAE5 Argininosuccinate lyase; ASAL; ASL; Arginosuccinase; EC 4.3.2.1 from Nostoc punctiforme (strain ATCC 29133 / PCC 73102) (see paper)
Q9LAE5 argininosuccinate lyase (EC 4.3.2.1) from Nostoc sp. (see paper)
47% identity, 99% coverage of query (451 bits)
ARLY_NOSS1 / Q8YQE6 Argininosuccinate lyase; ASAL; Arginosuccinase; NoArgH; EC 4.3.2.1 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see paper)
47% identity, 98% coverage of query (449 bits)
ARLY_SYNY3 / P73257 Argininosuccinate lyase; ASAL; Arginosuccinase; SyArgH; EC 4.3.2.1 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
46% identity, 100% coverage of query (445 bits)
ARLY_ARTPN / P0DXD4 Argininosuccinate lyase; ASAL; ArArgH; Arginosuccinase; EC 4.3.2.1 from Arthrospira platensis (strain NIES-39 / UTEX 3086 / IAM M-135) (Spirulina platensis) (see paper)
47% identity, 98% coverage of query (443 bits)
argH / BAC65282.1 argininosuccinate lyase from Burkholderia multivorans (see paper)
45% identity, 96% coverage of query (396 bits)
arg7 / RF|NP_595129.1 argininosuccinate lyase; EC 4.3.2.1 from Schizosaccharomyces pombe (see paper)
44% identity, 100% coverage of query (392 bits)
2e9fB / Q5SLL0 Crystal structure of t.Th.Hb8 argininosuccinate lyase complexed with l-arginine
44% identity, 95% coverage of query (382 bits)
Q9P870 argininosuccinate lyase (EC 4.3.2.1) from Agaricus bisporus (see paper)
41% identity, 98% coverage of query (372 bits)
ArgH / b3960 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
argH / P11447 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli (strain K12) (see 2 papers)
41% identity, 98% coverage of query (371 bits)
ARG7 / CAA09001.1 argininosuccinate lyase from Chlamydomonas reinhardtii (see paper)
44% identity, 98% coverage of query (371 bits)
1tj7B / P11447 Structure determination and refinement at 2.44 a resolution of argininosuccinate lyase from e. Coli (see paper)
41% identity, 98% coverage of query (365 bits)
ARLY_MOUSE / Q91YI0 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Mus musculus (Mouse) (see paper)
41% identity, 99% coverage of query (364 bits)
ASL / P04424 argininosuccinate lyase (EC 4.3.2.1) from Homo sapiens (see 5 papers)
ARLY_HUMAN / P04424 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Homo sapiens (Human) (see 11 papers)
41% identity, 99% coverage of query (360 bits)
ARLY2_ANAPL / P24058 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin II; Delta-2 crystallin; EC 4.3.2.1 from Anas platyrhynchos (Mallard) (Anas boschas) (see 6 papers)
42% identity, 98% coverage of query (359 bits)
ARLY1_ANAPL / P24057 Delta-1 crystallin; Delta crystallin I from Anas platyrhynchos (Mallard) (Anas boschas) (see 4 papers)
41% identity, 99% coverage of query (356 bits)
ARLY_ANSAN / P33110 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Anser anser anser (Western greylag goose) (see 2 papers)
42% identity, 98% coverage of query (355 bits)
ARLY_COLLI / Q01592 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Columba livia (Rock dove) (see 2 papers)
41% identity, 99% coverage of query (355 bits)
ARLY_YEAST / P04076 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
41% identity, 100% coverage of query (355 bits)
1hy0A Crystal structure of wild type duck delta 1 crystallin (eye lens protein)
42% identity, 95% coverage of query (354 bits)
1k7wD / P24058 Crystal structure of s283a duck delta 2 crystallin mutant (see paper)
43% identity, 94% coverage of query (353 bits)
AN2914 arginosuccinate lyase (Eurofung) from Emericella nidulans (see paper)
41% identity, 97% coverage of query (352 bits)
ARG4 argininosuccinate lyase from Candida albicans (see paper)
40% identity, 97% coverage of query (347 bits)
argH(A) / CAB95024.1 argininosuccinase and n-acetylglutamate synthase from Moritella abyssi (see paper)
41% identity, 98% coverage of query (343 bits)
ARLY1_CHICK / P02521 Delta-1 crystallin; Delta crystallin I from Gallus gallus (Chicken) (see 2 papers)
40% identity, 98% coverage of query (337 bits)
ARLY1_MELGA / Q7SIE0 Delta-1 crystallin; Delta crystallin I from Meleagris gallopavo (Wild turkey) (see paper)
40% identity, 98% coverage of query (337 bits)
argH / CAA88927.2 argininosuccinate lyase from Streptomyces clavuligerus (see 3 papers)
39% identity, 98% coverage of query (315 bits)
P9WPY7 argininosuccinate lyase (EC 4.3.2.1) from Mycobacterium tuberculosis (see 2 papers)
37% identity, 98% coverage of query (290 bits)
6ienB / P9WPY7 Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis (see paper)
37% identity, 93% coverage of query (281 bits)
6ienA Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis
36% identity, 93% coverage of query (271 bits)
6ienC Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis
38% identity, 85% coverage of query (270 bits)
Echvi_3852 arginosuccinate lyase (EC 4.3.2.1) from Echinicola vietnamensis KMM 6221, DSM 17526
33% identity, 88% coverage of query (209 bits)
6g3fA / Q11KV9 Crystal structure of edds lyase in complex with fumarate (see paper)
31% identity, 95% coverage of query (205 bits)
6g3iA Crystal structure of edds lyase in complex with n-(2-aminoethyl) aspartic acid (aeaa)
31% identity, 95% coverage of query (205 bits)
6g3hA Crystal structure of edds lyase in complex with ss-edds
31% identity, 95% coverage of query (205 bits)
6g3gA Crystal structure of edds lyase in complex with succinate
31% identity, 95% coverage of query (205 bits)
CA265_RS18485 arginosuccinate lyase (EC 4.3.2.1) from Pedobacter sp. GW460-11-11-14-LB5
32% identity, 87% coverage of query (202 bits)
BT3733 arginosuccinate lyase (EC 4.3.2.1) from Bacteroides thetaiotaomicron VPI-5482
33% identity, 84% coverage of query (201 bits)
Build an alignment for WP_012505623.1 and 38 homologs with ≥ 30% identity
Or download the sequences
ABZR86_RS08695 arginosuccinate lyase (EC 4.3.2.1) from Dyella japonica UNC79MFTsu3.2
29% identity, 82% coverage of query (164 bits)
MJ0929 / Q58339 adenylosuccinate lyase (EC 4.3.2.2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
28% identity, 85% coverage of query (97.1 bits)
3r6vG / Q9LCC6 Crystal structure of aspartase from bacillus sp. Ym55-1 with bound l- aspartate (see paper)
25% identity, 74% coverage of query (73.6 bits)
ASPA_BACSP / Q9LCC6 Aspartate ammonia-lyase; Aspartase; EC 4.3.1.1 from Bacillus sp. (see 7 papers)
Q9LCC6 aspartate ammonia-lyase (EC 4.3.1.1) from Bacillus sp. (in: Bacteria) (see 4 papers)
25% identity, 74% coverage of query (73.6 bits)
3r6qA A triclinic-lattice structure of aspartase from bacillus sp. Ym55-1
25% identity, 74% coverage of query (73.6 bits)
PUR8_STAAW / Q7A0G9 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Staphylococcus aureus (strain MW2) (see paper)
Q7A0G9 adenylosuccinate lyase (EC 4.3.2.2) from Staphylococcus aureus (see paper)
21% identity, 92% coverage of query (72.4 bits)
2x75A / Q7A0G9 Staphylococcus aureus adenylosuccinate lyase (see paper)
22% identity, 82% coverage of query (71.6 bits)
FUMH_YEAST / P08417 Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
P08417 fumarate hydratase (EC 4.2.1.2) from Saccharomyces cerevisiae (see 2 papers)
23% identity, 78% coverage of query (60.8 bits)
2SL_ENTI1 / E6LDH5 N-acetyl-S-(2-succino)cysteine lyase; S-(2-succino) lyase; 2SL; EC 4.3.2.- from Enterococcus italicus (strain DSM 15952 / CCUG 50447 / LMG 22039 / TP 1.5) (see paper)
24% identity, 72% coverage of query (60.8 bits)
ASPA_PSECO / P0DXC8 Aspartate ammonia-lyase; Aspartase; EC 4.3.1.1 from Pseudomonas canavaninivorans (see paper)
25% identity, 71% coverage of query (60.8 bits)
6wngA / A0A077EBQ3 Crystal structure of an aspartate ammonia-lyase from elizabethkingia anophelis nuhp1
24% identity, 75% coverage of query (59.3 bits)
PUR8_BACSU / P12047 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; Glutamyl--tRNA ligase regulatory factor; EC 4.3.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
P12047 adenylosuccinate lyase (EC 4.3.2.2) from Bacillus subtilis (see paper)
purB / GI|143366 (glutamyl-trna synthetase regulatory factor); EC 4.3.2.2 from Bacillus subtilis (see 4 papers)
21% identity, 72% coverage of query (55.8 bits)
Or start over
Lawrence Berkeley National Laboratory