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Searching for up to 100 curated homologs for WP_012506069.1 NCBI__GCF_000020625.1:WP_012506069.1 (197 a.a.)

Found high-coverage hits (≥70%) to 28 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

CCNA_03103 shikimate kinase (EC 2.7.1.71) from Caulobacter crescentus NA1000
    38% identity, 78% coverage of query (102 bits)

A0A0M3KL09 shikimate kinase (EC 2.7.1.71) from Acinetobacter baumannii (see paper)
4y0aA / A0A0M3KL09 Shikimate kinase from acinetobacter baumannii in complex with shikimate (see paper)
    36% identity, 79% coverage of query (92.8 bits)

SK3_ORYSJ / Q7X7H9 Shikimate kinase 3, chloroplastic; OsSK3; EC 2.7.1.71 from Oryza sativa subsp. japonica (Rice) (see paper)
Q7X7H9 shikimate kinase (EC 2.7.1.71) from Oryza sativa (see paper)
    35% identity, 77% coverage of query (82.8 bits)

SK_SOLLC / Q00497 Shikimate kinase, chloroplastic; EC 2.7.1.71 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
    36% identity, 77% coverage of query (80.5 bits)

AroK / b3390 shikimate kinase 1 (EC 2.7.1.71) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
aroK / P0A6D7 shikimate kinase 1 (EC 2.7.1.71) from Escherichia coli (strain K12) (see 30 papers)
AROK_ECOLI / P0A6D7 Shikimate kinase 1; SK 1; Shikimate kinase I; SKI; EC 2.7.1.71 from Escherichia coli (strain K12) (see 3 papers)
P0A6D7 shikimate kinase (EC 2.7.1.71) from Escherichia coli (see paper)
aroK / AAB59099.1 shikimic acid kinase I from Escherichia coli (see paper)
    30% identity, 90% coverage of query (79.7 bits)

AROK_MYCTU / P9WPY3 Shikimate kinase; SK; EC 2.7.1.71 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 7 papers)
P9WPY3 shikimate kinase (EC 2.7.1.71) from Mycobacterium tuberculosis (see 8 papers)
    31% identity, 86% coverage of query (78.6 bits)

4bqsA Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with adp and a shikimic acid derivative.
    31% identity, 86% coverage of query (78.6 bits)

2iyyA Shikimate kinase from mycobacterium tuberculosis in complex with shikimate-3-phosphate and so4
    31% identity, 86% coverage of query (78.6 bits)

1zyuA Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and amppcp at 2.85 angstrom resolution
    31% identity, 86% coverage of query (78.6 bits)

2iywA Shikimate kinase from mycobacterium tuberculosis in complex with mgatp, open lid (conf. B)
    31% identity, 86% coverage of query (78.6 bits)

2iyvA / P9WPY3 Shikimate kinase from mycobacterium tuberculosis in complex with adp, open lid (conf. B) (see paper)
    31% identity, 86% coverage of query (78.2 bits)

SK2_ORYSJ / Q5NTH3 Shikimate kinase 2, chloroplastic; OsSK2; EC 2.7.1.71 from Oryza sativa subsp. japonica (Rice) (see paper)
Q5NTH3 shikimate kinase (EC 2.7.1.71) from Oryza sativa (see paper)
    35% identity, 77% coverage of query (77.8 bits)

3bafA Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with amp-pnp
    31% identity, 85% coverage of query (77.8 bits)

2dfnA Structure of shikimate kinase from mycobacterium tuberculosis complexed with adp and shikimate at 1.9 angstrons of resolution
    31% identity, 85% coverage of query (77.8 bits)

1we2A Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with mgadp and shikimic acid
    31% identity, 85% coverage of query (77.8 bits)

SK1_ORYSJ / Q5NTH4 Shikimate kinase 1, chloroplastic; OsSK1; EC 2.7.1.71 from Oryza sativa subsp. japonica (Rice) (see paper)
Q5NTH4 shikimate kinase (EC 2.7.1.71) from Oryza sativa (see paper)
    33% identity, 88% coverage of query (76.6 bits)

AROL_DICCH / P10880 Shikimate kinase 2; SK 2; Shikimate kinase II; SKII; EC 2.7.1.71 from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 4 papers)
    33% identity, 89% coverage of query (74.7 bits)

2shkB The three-dimensional structure of shikimate kinase from erwinia chrysanthemi complexed with adp
    35% identity, 72% coverage of query (73.6 bits)

1u8aA Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and adp at 2.15 angstrom resolution
    31% identity, 85% coverage of query (73.2 bits)

SK1 / Q9SJ05 shikimate kinase (EC 2.7.1.71) from Arabidopsis thaliana (see 3 papers)
SK1_ARATH / Q9SJ05 Shikimate kinase 1, chloroplastic; AtSK1; EC 2.7.1.71 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    31% identity, 85% coverage of query (72.4 bits)

1e6cA / P10880 K15m mutant of shikimate kinase from erwinia chrysanthemi (see paper)
    32% identity, 89% coverage of query (72.0 bits)

AroL / b0388 shikimate kinase 2 (EC 2.7.1.71) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
aroL / P0A6E1 shikimate kinase 2 (EC 2.7.1.71) from Escherichia coli (strain K12) (see 8 papers)
AROL_ECOLI / P0A6E1 Shikimate kinase 2; SK 2; Shikimate kinase II; SKII; EC 2.7.1.71 from Escherichia coli (strain K12) (see 5 papers)
    31% identity, 81% coverage of query (68.2 bits)

SK2 / Q8GY88 shikimate kinase (EC 2.7.1.71) from Arabidopsis thaliana (see 3 papers)
SK2_ARATH / Q8GY88 Shikimate kinase 2, chloroplastic; AtSK2; EC 2.7.1.71 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8GY88 shikimate kinase (EC 2.7.1.71) from Arabidopsis thaliana (see paper)
    30% identity, 85% coverage of query (66.2 bits)

Build an alignment

Build an alignment for WP_012506069.1 and 23 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

bzdR / AAQ08805.1 BzdR from Azoarcus sp. CIB (see paper)
    28% identity, 84% coverage of query (62.0 bits)

6hqvA / G0S061 Pentafunctional arom complex from chaetomium thermophilum (see paper)
    30% identity, 74% coverage of query (57.8 bits)

KAD6_PYRAB / Q9UZK4 Putative adenylate kinase; AK; ATP-AMP transphosphorylase; EC 2.7.4.3 from Pyrococcus abyssi (strain GE5 / Orsay) (see paper)
    26% identity, 90% coverage of query (44.3 bits)

4cvnA Structure of the fap7-rps14 complex
    26% identity, 90% coverage of query (44.3 bits)

4cw7A / Q9UZK4 Structure of the fap7-rps14 complex in complex with atp (see paper)
    26% identity, 90% coverage of query (43.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory