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Searching for up to 100 curated homologs for WP_012536751.1 NCBI__GCF_000021485.1:WP_012536751.1 (514 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

O85192 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Lacticaseibacillus rhamnosus (see paper)
    55% identity, 100% coverage of query (577 bits)

GuaA / b2507 GMP synthetase (EC 6.3.5.2) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
guaA / P04079 GMP synthetase (EC 6.3.5.2) from Escherichia coli (strain K12) (see 15 papers)
GUAA_ECOLI / P04079 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; GMPS; Glutamine amidotransferase; EC 6.3.5.2 from Escherichia coli (strain K12) (see paper)
P04079 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Escherichia coli (see 3 papers)
guaA / GB|AAC75560.1 GMP synthase [glutamine-hydrolyzing]; EC 6.3.5.2 from Escherichia coli K12 (see 9 papers)
    55% identity, 100% coverage of query (572 bits)

GUAA_CRYNH / J9VUY6 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) (see paper)
    54% identity, 100% coverage of query (562 bits)

GUA1 / P38625 GMP synthase monomer (EC 6.3.5.2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
GUAA_YEAST / P38625 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    52% identity, 100% coverage of query (558 bits)

GUA1 GMP synthase [glutamine-hydrolyzing]; EC 6.3.5.2 from Candida albicans (see 2 papers)
    53% identity, 100% coverage of query (555 bits)

1gpmA / P04079 Escherichia coli gmp synthetase complexed with amp and pyrophosphate (see paper)
    52% identity, 100% coverage of query (535 bits)

5tw7F / B4RJH7 Crystal structure of a gmp synthase (glutamine-hydrolyzing) from neisseria gonorrhoeae
    53% identity, 100% coverage of query (531 bits)

GUAA_MYCTU / P9WMS7 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    55% identity, 99% coverage of query (530 bits)

GUAA_SCHPO / Q9P772 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    52% identity, 100% coverage of query (527 bits)

GUAA_ASPFU / Q4WFT3 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
    51% identity, 100% coverage of query (514 bits)

GUAA_PLAF7 / Q8IJR9 GMP synthase [glutamine-hydrolyzing]; PfGMPS; Glutamine amidotransferase; Guanosine monophosphate synthetase; EC 6.3.5.2 from Plasmodium falciparum (isolate 3D7) (see 6 papers)
    42% identity, 100% coverage of query (461 bits)

2ywcA / Q5SI28 Crystal structure of gmp synthetase from thermus thermophilus in complex with xmp
    49% identity, 99% coverage of query (442 bits)

GMPS / GI|6456564 GMP synthetase; EC 6.3.4.1 from Plasmodium falciparum (see paper)
    40% identity, 100% coverage of query (439 bits)

4wioA / Q8IJR9 Crystal structure of the c89a gmp synthetase inactive mutant from plasmodium falciparum in complex with glutamine (see paper)
    40% identity, 100% coverage of query (415 bits)

3uowA Crystal structure of pf10_0123, a gmp synthetase from plasmodium falciparum
    38% identity, 100% coverage of query (399 bits)

3uowB / Q8IJR9 Crystal structure of pf10_0123, a gmp synthetase from plasmodium falciparum
    40% identity, 99% coverage of query (378 bits)

GUAA_MOUSE / Q3THK7 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Mus musculus (Mouse) (see paper)
    36% identity, 97% coverage of query (310 bits)

GUAA_RAT / Q4V7C6 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Rattus norvegicus (Rat) (see paper)
    36% identity, 97% coverage of query (310 bits)

GUAA_HUMAN / P49915 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Homo sapiens (Human) (see 2 papers)
P49915 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Homo sapiens (see paper)
    36% identity, 97% coverage of query (309 bits)

2vxoB / P49915 Human gmp synthetase in complex with xmp (see paper)
    36% identity, 97% coverage of query (305 bits)

Build an alignment

Build an alignment for WP_012536751.1 and 20 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory