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Searching for up to 100 curated homologs for WP_012566052.1 NCBI__GCF_000016185.1:WP_012566052.1 (208 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q5FAE1 UDP-N-acetylbacillosamine N-acetyltransferase (EC 2.3.1.203) from Neisseria gonorrhoeae (see paper)
    40% identity, 98% coverage of query (130 bits)

4m99A / Q5FAE1 Acetyltransferase domain of pglb from neisseria gonorrhoeae fa1090 in complex with acetyl coenzyme a (see paper)
    40% identity, 98% coverage of query (130 bits)

EPSM_BACSU / P71063 UDP-N-acetylbacillosamine N-acetyltransferase; EC 2.3.1.203 from Bacillus subtilis (strain 168) (see 3 papers)
    36% identity, 97% coverage of query (112 bits)

perB / Q7DBF7 GDP-perosamine N-acetyltransferase monomer (EC 2.3.1.227) from Escherichia coli O157:H7 (see 2 papers)
PERB_ECO57 / Q7DBF7 GDP-perosamine N-acetyltransferase; EC 2.3.1.227 from Escherichia coli O157:H7 (see paper)
    33% identity, 97% coverage of query (108 bits)

7txpA / A0A334FGR6 X-ray structure of the viob n-acetyltransferase from acinetobacter baumannii in complex with tdp-4-amino-4,6-dideoxy-d-glucose (see paper)
    34% identity, 98% coverage of query (108 bits)

7txsA X-ray structure of the viob n-aetyltransferase from acinetobacter baumannii in the presence of a reaction intermediate
    34% identity, 98% coverage of query (108 bits)

7txqA X-ray structure of the viob n-acetyltransferase from acinetobacter baumannii in the present of tdp and acetyl-coenzymea
    34% identity, 98% coverage of query (108 bits)

4ea9A X-ray structure of gdp-perosamine n-acetyltransferase in complex with transition state analog at 0.9 angstrom resolution
    36% identity, 92% coverage of query (103 bits)

4ea8A X-ray crystal structure of perb from caulobacter crescentus in complex with coenzyme a and gdp-n-acetylperosamine at 1 angstrom resolution
    36% identity, 92% coverage of query (103 bits)

4eaaA / O85353 X-ray crystal structure of the h141n mutant of perosamine n- acetyltransferase from caulobacter crescentus in complex with coa and gdp-perosamine (see paper)
    36% identity, 92% coverage of query (102 bits)

Build an alignment

Build an alignment for WP_012566052.1 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

pglD / Q0P9D1 UDP-4-amino-4,6-dideoxy-α-D-N-acetyl-D-glucosamine N-acetyltransferase subunit (EC 2.3.1.203) from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see 3 papers)
PGLD_CAMJE / Q0P9D1 UDP-N-acetylbacillosamine N-acetyltransferase; Protein glycosylation D; UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase; EC 2.3.1.203 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see 4 papers)
Q0P9D1 UDP-N-acetylbacillosamine N-acetyltransferase (EC 2.3.1.203) from Campylobacter jejuni subsp. jejuni (see paper)
    29% identity, 98% coverage of query (98.6 bits)

3bssA / Q0P9D1 Pgld from campylobacter jejuni, nctc 11168, with native substrate (see paper)
    29% identity, 98% coverage of query (98.6 bits)

2vheA Pgld-coa complex: an acetyl transferase from campylobacter jejuni
    29% identity, 98% coverage of query (98.6 bits)

3bsyA Pgld from campylobacter jejuni, nctc 11168, in complex with acetyl coenzyme a
    29% identity, 98% coverage of query (98.6 bits)

5t2yA Crystal structure of c. Jejuni pgld in complex with 5-methyl-4- (methylamino)-2-phenethylthieno[2,3-d]pyrimidine-6-carboxylic acid
    29% identity, 98% coverage of query (96.3 bits)

B0V6J7 UDP-N-acetylbacillosamine N-acetyltransferase (EC 2.3.1.203) from Acinetobacter baumannii (see paper)
    33% identity, 97% coverage of query (94.7 bits)

Q46674 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase (EC 2.3.1.45) from Escherichia coli (see paper)
    25% identity, 98% coverage of query (89.7 bits)

wckD / Q93NQ3 sialate O-acetyltransferase from Escherichia coli (see 7 papers)
    26% identity, 100% coverage of query (89.0 bits)

C4B8D3 dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase (EC 2.3.1.209) from Pseudomonas syringae (see paper)
    32% identity, 95% coverage of query (88.2 bits)

5tyhA Pgld from campylobacter jejuni nctc 11168 in complex with 5-(2- furanyl)-1h-pyrazole-3-carboxylic acid
    28% identity, 93% coverage of query (86.7 bits)

D9E73_16825 / A0A0A8J6R7 dTDP-viosamine (S)-3-hydroxybutanoyltransferase from Escherichia coli (see paper)
    29% identity, 96% coverage of query (85.9 bits)

orf5 / A0A0A8J540 UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-idosamine acetyltransferase from Escherichia coli (see paper)
    29% identity, 100% coverage of query (83.6 bits)

7l7yAAA / Q1QD33 7l7yAAA (see paper)
    29% identity, 98% coverage of query (81.3 bits)

7l82AAA Putative acetyl transferase protein
    29% identity, 98% coverage of query (80.9 bits)

7l81AAA Putative acetyl transferase protein
    29% identity, 98% coverage of query (80.9 bits)

7l7zAAA Putative acetyl transferase protein
    29% identity, 98% coverage of query (80.9 bits)

cpsI polysaccharide capsule synthesis protein CpsI from Streptococcus iniae (see paper)
    23% identity, 75% coverage of query (49.7 bits)

3nz2C Crystal structure of hexapeptide-repeat containing-acetyltransferase vca0836 complexed with acetyl co enzyme a from vibrio cholerae o1 biovar eltor
    25% identity, 80% coverage of query (43.1 bits)

3nz2J / Q9KLB0 Crystal structure of hexapeptide-repeat containing-acetyltransferase vca0836 complexed with acetyl co enzyme a from vibrio cholerae o1 biovar eltor
    25% identity, 80% coverage of query (43.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory