Searching for up to 100 curated homologs for WP_012566228.1 NCBI__GCF_000016185.1:WP_012566228.1 (422 a.a.)
Found high-coverage hits (≥70%) to 72 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Echvi_1295 diaminopimelate decarboxylase (EC 4.1.1.20) from Echinicola vietnamensis KMM 6221, DSM 17526
30% identity, 93% coverage of query (163 bits)
ABZR86_RS19560 aspartate kinase / diaminopimelate decarboxylase (EC 4.1.1.20; EC 2.7.2.4) from Dyella japonica UNC79MFTsu3.2
33% identity, 88% coverage of query (159 bits)
lysA / BAC66455.1 Diaminopimelate decarboxylase from Burkholderia multivorans (see paper)
30% identity, 92% coverage of query (159 bits)
1knwA / P00861 Crystal structure of diaminopimelate decarboxylase
30% identity, 90% coverage of query (146 bits)
LysA / b2838 diaminopimelate decarboxylase (EC 4.1.1.20) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
lysA / P00861 diaminopimelate decarboxylase (EC 4.1.1.20) from Escherichia coli (strain K12) (see 33 papers)
DCDA_ECOLW / E0IWI3 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / LMG 11080 / NBRC 13500 / NCIMB 8666 / NRRL B-766 / W) (see paper)
DCDA_ECOLI / P00861 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Escherichia coli (strain K12) (see 5 papers)
P00861 diaminopimelate decarboxylase (EC 4.1.1.20) from Escherichia coli (see 2 papers)
30% identity, 90% coverage of query (146 bits)
1ko0A Crystal structure of a d,l-lysine complex of diaminopimelate decarboxylase
30% identity, 90% coverage of query (146 bits)
Build an alignment for WP_012566228.1 and 6 homologs with ≥ 30% identity
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A0A0H3H393 lysine decarboxylase (EC 4.1.1.18) from Klebsiella oxytoca (see paper)
29% identity, 90% coverage of query (138 bits)
DCDA_STAAC / Q5HG20 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Staphylococcus aureus (strain COL) (see paper)
27% identity, 92% coverage of query (131 bits)
lysA / P23630 diaminopimelate decarboxylase subunit (EC 4.1.1.20) from Bacillus subtilis (strain 168) (see paper)
27% identity, 89% coverage of query (120 bits)
4xg1B / A1SR00 Psychromonas ingrahamii diaminopimelate decarboxylase with llp
26% identity, 92% coverage of query (119 bits)
AT3G14390 / Q949X7 diaminopimelate decarboxylase (EC 4.1.1.20) from Arabidopsis thaliana (see paper)
DCDA1_ARATH / Q949X7 Diaminopimelate decarboxylase 1, chloroplastic; DAP decarboxylase 1; DAPDC 1; EC 4.1.1.20 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q949X7 diaminopimelate decarboxylase (EC 4.1.1.20) from Arabidopsis thaliana (see paper)
26% identity, 87% coverage of query (117 bits)
6n2aA / Q949X7 Meso-diaminopimelate decarboxylase from arabidopsis thaliana (isoform 1)
26% identity, 87% coverage of query (117 bits)
Q9KVL7 diaminopimelate decarboxylase (EC 4.1.1.20) from Vibrio cholerae serotype O1 (see paper)
29% identity, 90% coverage of query (117 bits)
2yxxA / Q9X1K5 Crystal structure analysis of diaminopimelate decarboxylate (lysa)
28% identity, 90% coverage of query (116 bits)
DCDA_THEMA / Q9X1K5 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
28% identity, 90% coverage of query (116 bits)
AT5G11880 / Q94A94 diaminopimelate decarboxylase (EC 4.1.1.20) from Arabidopsis thaliana (see paper)
DCDA2_ARATH / Q94A94 Diaminopimelate decarboxylase 2, chloroplastic; DAP decarboxylase 2; DAPDC 2; EC 4.1.1.20 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q94A94 diaminopimelate decarboxylase (EC 4.1.1.20) from Arabidopsis thaliana (see paper)
26% identity, 87% coverage of query (114 bits)
3c5qA / B4XMC6 Crystal structure of diaminopimelate decarboxylase (i148l mutant) from helicobacter pylori complexed with l-lysine
24% identity, 90% coverage of query (110 bits)
B8BT13 dimethylsulfonio-2-hydroxybutanoate hydroxylase/decarboxylase from Thalassiosira pseudonana (see 2 papers)
29% identity, 87% coverage of query (107 bits)
DCDA_HELPX / B4XMC6 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Helicobacter pylori (Campylobacter pylori) (see paper)
24% identity, 90% coverage of query (107 bits)
4xg1A / A1SR00 Psychromonas ingrahamii diaminopimelate decarboxylase with llp
25% identity, 92% coverage of query (106 bits)
Ga0059261_2051 diaminopimelate decarboxylase (EC 4.1.1.20) from Sphingomonas koreensis DSMZ 15582
28% identity, 92% coverage of query (105 bits)
DCDA_METJA / Q58497 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
25% identity, 91% coverage of query (105 bits)
1tufA / Q58497 Crystal structure of diaminopimelate decarboxylase from m. Jannaschi (see paper)
25% identity, 91% coverage of query (104 bits)
1twiA Crystal structure of diaminopimelate decarboxylase from m. Jannaschii in co-complex with l-lysine
25% identity, 91% coverage of query (104 bits)
P56129 diaminopimelate decarboxylase (EC 4.1.1.20) from Helicobacter pylori (see paper)
23% identity, 90% coverage of query (100 bits)
8d5dA Structure of y430f d-ornithine/d-lysine decarboxylase complex with d- arginine
26% identity, 90% coverage of query (99.8 bits)
8d5rA Structure of y430f d-ornithine/d-lysine decarboxylase complex with d- ornithine
26% identity, 90% coverage of query (97.1 bits)
dokD / Q8ZNC4 D-lysine decarboxylase (EC 4.1.1.116) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
DOKDC_SALTY / Q8ZNC4 D-ornithine/D-lysine decarboxylase; D-Orn/D-Lys decarboxylase; DOKDC; EC 4.1.1.116 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZNC4 D-ornithine/D-lysine decarboxylase (EC 4.1.1.116) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
26% identity, 90% coverage of query (95.9 bits)
8d4iA / Q8ZNC4 Structure of y430f d-ornithine/d-lysine decarboxylase complex with putrescine (see paper)
26% identity, 90% coverage of query (94.4 bits)
8d88A Structure of y430f d-ornithine/d-lysine decarboxylase complex with d- lysine
26% identity, 90% coverage of query (94.4 bits)
BT1374 diaminopimelate decarboxylase (EC 4.1.1.20) from Bacteroides thetaiotaomicron VPI-5482
24% identity, 87% coverage of query (94.0 bits)
7ru7A / Q2L4H3 Crystal structure of btrk, a decarboxylase involved in butirosin biosynthesis
23% identity, 90% coverage of query (90.9 bits)
btrK / Q2L4H3 L-glutamyl-[BtrI acyl-carrier protein] decarboxylase monomer (EC 4.1.1.95) from Niallia circulans (see paper)
BTRK_NIACI / Q2L4H3 L-glutamyl-[BtrI acyl-carrier protein] decarboxylase; Butirosin biosynthesis protein K; EC 4.1.1.95 from Niallia circulans (Bacillus circulans) (see paper)
23% identity, 90% coverage of query (84.0 bits)
1hkvA / P9WIU7 Mycobacterium diaminopimelate dicarboxylase (lysa) (see paper)
25% identity, 95% coverage of query (83.2 bits)
DCDA_MYCTU / P9WIU7 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WIU7 diaminopimelate decarboxylase (EC 4.1.1.20) from Mycobacterium tuberculosis (see 5 papers)
25% identity, 95% coverage of query (83.2 bits)
5x7mA / P09890 Crystal structure of meso-diaminopimelate decarboxylase (dapdc) from corynebacterium glutamicum (see paper)
27% identity, 93% coverage of query (75.5 bits)
DCDA_CORGL / P09890 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
P09890 diaminopimelate decarboxylase (EC 4.1.1.20) from Corynebacterium glutamicum (see paper)
27% identity, 93% coverage of query (75.5 bits)
5x7nA Crystal structure of meso-diaminopimelate decarboxylase (dapdc) from corynebacterium glutamicum
27% identity, 93% coverage of query (75.5 bits)
C9W982 ornithine decarboxylase (EC 4.1.1.17) from Grateloupia imbricata (see paper)
25% identity, 77% coverage of query (70.9 bits)
Q58P26 ornithine decarboxylase (EC 4.1.1.17) from Entamoeba histolytica (see 3 papers)
23% identity, 78% coverage of query (70.5 bits)
Q54UF3 ornithine decarboxylase (EC 4.1.1.17) from Dictyostelium discoideum (see paper)
23% identity, 78% coverage of query (67.0 bits)
1f3tB / P07805 Crystal structure of trypanosoma brucei ornithine decarboxylase (odc) complexed with putrescine, odc's reaction product. (see paper)
23% identity, 78% coverage of query (66.6 bits)
2nvaA The x-ray crystal structure of the paramecium bursaria chlorella virus arginine decarboxylase bound to agmatine
23% identity, 85% coverage of query (65.1 bits)
2nv9B / Q84527 The x-ray crystal structure of the paramecium bursaria chlorella virus arginine decarboxylase (see paper)
22% identity, 85% coverage of query (64.7 bits)
sbnH / Q2G1M6 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase (EC 4.1.1.117) from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
SBNH_STAA8 / Q2G1M6 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase; Staphyloferrin B biosynthesis protein SbnH; EC 4.1.1.117 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 2 papers)
Q2G1M6 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase (EC 4.1.1.117) from Staphylococcus aureus (see paper)
22% identity, 88% coverage of query (64.7 bits)
1njjA Crystal structure determination of t. Brucei ornithine decarboxylase bound to d-ornithine and to g418
23% identity, 77% coverage of query (64.7 bits)
5gjoA / O50657 Crystal structure of srldc mutant (a225c/t302c) in complex with plp (see paper)
23% identity, 88% coverage of query (64.3 bits)
5gjpA Crystal structure of srldc in complex with plp and cadaverine
22% identity, 88% coverage of query (62.8 bits)
AZIN2_XENLA / Q9I8S4 Antizyme inhibitor 2; AzI2; Ornithine decarboxylase 2; ODC 2; xODC2; Ornithine decarboxylase-like protein; ODC-like protein; ornithine decarboxylase paralog; ODC-p from Xenopus laevis (African clawed frog) (see paper)
23% identity, 93% coverage of query (62.4 bits)
ldc / O50657 L-lysine decarboxylase monomer (EC 4.1.1.18) from Selenomonas ruminantium (see paper)
ldc / BAC57940.1 lysine decarboxylase from Selenomonas ruminantium (see paper)
23% identity, 88% coverage of query (61.6 bits)
O50657 Lysine/ornithine decarboxylase; LDC; EC 4.1.1.17; EC 4.1.1.18 from Selenomonas ruminantium
23% identity, 88% coverage of query (61.6 bits)
4zgyA Structure of human ornithine decarboxylase in complex with a c- terminal fragment of antizyme
24% identity, 85% coverage of query (61.6 bits)
1szrC A dimer interface mutant of ornithine decarboxylase reveals structure of gem diamine intermediate
23% identity, 78% coverage of query (61.2 bits)
ODC_NICGL / E0WN94 Ornithine decarboxylase, chloroplastic; EC 4.1.1.17 from Nicotiana glauca (Glaucous tobacco) (Tree tobacco) (see 2 papers)
23% identity, 85% coverage of query (60.8 bits)
6knhC / A0A0H3JPF2 Crystal structure of sbnh in complex with citrate, a plp-dependent decarboxylase in staphyloferrin b biothesynthesis (see paper)
21% identity, 83% coverage of query (60.1 bits)
2oo0A / P11926 A structural insight into the inhibition of human and leishmania donovani ornithine decarboxylases by 3-aminooxy-1-aminopropane (see paper)
24% identity, 84% coverage of query (59.7 bits)
ODC1B_TOBAC / P93351 Ornithine decarboxylase 1B, chloroplastic; Nt-ODC; EC 4.1.1.17 from Nicotiana tabacum (Common tobacco) (see 3 papers)
23% identity, 85% coverage of query (58.9 bits)
ODC1A_TOBAC / A0A1S4AUX8 Ornithine decarboxylase 1A, chloroplastic; EC 4.1.1.17 from Nicotiana tabacum (Common tobacco) (see 2 papers)
23% identity, 85% coverage of query (58.5 bits)
ODC / P50134 ornithine decarboxylase (EC 4.1.1.17) from Datura stramonium (see paper)
23% identity, 79% coverage of query (57.8 bits)
5gjnA Crystal structure of lysine decarboxylase from selenomonas ruminantium in p43212 space group
22% identity, 88% coverage of query (57.8 bits)
DCOR_TRYBB / P07805 Ornithine decarboxylase; ODC; EC 4.1.1.17 from Trypanosoma brucei brucei (see 3 papers)
24% identity, 78% coverage of query (57.0 bits)
ODC / Q8S3N2 ornithine decarboxylase (EC 4.1.1.17) from Capsicum annuum (see paper)
DCOR_CAPAN / Q8S3N2 Ornithine decarboxylase; ODC; CaODC1; CapODC; EC 4.1.1.17 from Capsicum annuum (Capsicum pepper) (see paper)
22% identity, 78% coverage of query (57.0 bits)
6knkA Crystal structure of sbnh in complex with citryl-diaminoethane
21% identity, 83% coverage of query (57.0 bits)
6kniA Crystal structure of sbnh in complex with the cofactor plp, a plp- dependent decarboxylase in staphyloferrin b biothesynthesis
20% identity, 88% coverage of query (57.0 bits)
7u6pA Structure of an intellectual disability-associated ornithine decarboxylase variant g84r
24% identity, 84% coverage of query (56.6 bits)
2todA Ornithine decarboxylase from trypanosoma brucei k69a mutant in complex with alpha-difluoromethylornithine
22% identity, 78% coverage of query (56.6 bits)
ODC_NICGU / Q9FPK5 Ornithine decarboxylase, chloroplastic; Lysine decarboxylase; EC 4.1.1.17; EC 4.1.1.18 from Nicotiana glutinosa (Tobacco) (see paper)
Q9FPK5 ornithine decarboxylase (EC 4.1.1.17) from Nicotiana glutinosa (see paper)
23% identity, 85% coverage of query (55.8 bits)
ODC1 / P11926 ornithine decarboxylase subunit (EC 4.1.1.17) from Homo sapiens (see 3 papers)
DCOR_HUMAN / P11926 Ornithine decarboxylase; ODC; EC 4.1.1.17 from Homo sapiens (Human) (see 8 papers)
23% identity, 84% coverage of query (55.5 bits)
P09057 ornithine decarboxylase (EC 4.1.1.17) from Rattus norvegicus (see 2 papers)
23% identity, 84% coverage of query (54.3 bits)
2pljA Crystal structure of lysine/ornithine decarboxylase complexed with putrescine from vibrio vulnificus (see paper)
20% identity, 88% coverage of query (53.5 bits)
DCOR_MOUSE / P00860 Ornithine decarboxylase; ODC; EC 4.1.1.17 from Mus musculus (Mouse) (see 5 papers)
P00860 ornithine decarboxylase (EC 4.1.1.17) from Mus musculus (see 6 papers)
24% identity, 84% coverage of query (53.5 bits)
2plkA Crystal structure of lysine/ornithine decarboxylase complexed with cadaverine from vibrio vulnificus
20% identity, 88% coverage of query (52.4 bits)
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Lawrence Berkeley National Laboratory