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Searching for up to 100 curated homologs for WP_012590119.1 NCBI__GCF_000021745.1:WP_012590119.1 (363 a.a.)

Found high-coverage hits (≥70%) to 40 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

CysA / b2422 sulfate/thiosulfate ABC transporter ATP binding subunit (EC 7.3.2.3; EC 7.3.2.5) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
CysA / P16676 sulfate/thiosulfate ABC transporter ATP binding subunit (EC 7.3.2.3; EC 7.3.2.5) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.6.1 / P16676 CysA aka B2422, component of Sulfate/thiosulfate porter from Escherichia coli (see 5 papers)
    53% identity, 79% coverage of query (290 bits)

TC 3.A.1.6.7 / Q6QJE1 Chloroplast ATP-binding protein, component of The chloroplast sulfate transporter, SulP/SulP2/Sabc/Sbp from Chlamydomonas reinhardtii (see 2 papers)
    50% identity, 82% coverage of query (266 bits)

YagC / b0262 CP4-6 prophage; ABC transporter ATP-binding protein AfuC from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    38% identity, 97% coverage of query (246 bits)

TC 3.A.1.20.3 / A3N296 Ferric ABC transporter ATP-binding protein, component of Iron (Fe3+) uptake porter, AfuABC (FbpABC) (Chin et al. 1996). AfuA has been characterized from Actinobacillus pleuropneumoniae serotype 5b (strain L20)
    42% identity, 83% coverage of query (239 bits)

TC 3.A.1.20.2 / Q9KLQ5 Fe(3+) ions import ATP-binding protein FbpC, component of Hexose-phosphate transporter from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    37% identity, 95% coverage of query (237 bits)

Ac3H11_2066 glucose ABC transporter, ATPase component from Acidovorax sp. GW101-3H11
    43% identity, 88% coverage of query (232 bits)

TC 3.A.1.20.1 / O54370 BitD, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
    39% identity, 83% coverage of query (229 bits)

PS417_27115 putrescine ABC transporter, ATPase component from Pseudomonas simiae WCS417
    43% identity, 76% coverage of query (228 bits)

PotG / b0855 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotG / P31134 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTG_ECOLI / P31134 Putrescine transport ATP-binding protein PotG; EC 7.6.2.16 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.2 / P31134 PotG aka B0855, component of Putrescine porter from Escherichia coli (see 4 papers)
    43% identity, 80% coverage of query (226 bits)

TC 3.A.1.1.22 / Q9X103 MalK; aka Sugar ABC transporter, ATP-binding protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
    42% identity, 79% coverage of query (225 bits)

TC 3.A.1.1.12 / Q9AI63 PalK, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
    42% identity, 83% coverage of query (224 bits)

TC 3.A.1.1.16 / Q8TZQ3 MalK aka PF1933, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
    44% identity, 74% coverage of query (223 bits)

UgpC / b3450 sn-glycerol 3-phosphate ABC transporter ATP binding subunit (EC 7.6.2.10) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
UgpC / P10907 sn-glycerol 3-phosphate ABC transporter ATP binding subunit (EC 7.6.2.10) from Escherichia coli (strain K12) (see 2 papers)
UGPC_ECOLI / P10907 sn-glycerol-3-phosphate import ATP-binding protein UgpC; EC 7.6.2.10 from Escherichia coli (strain K12) (see 9 papers)
TC 3.A.1.1.3 / P10907 UgpC aka B3450, component of Glycerol-phosphate porter. Transports both glycerol-3-P and glycerol-3-P diesters including glycerophosphocholine but not glycerol-2-P from Escherichia coli (see 12 papers)
    41% identity, 81% coverage of query (223 bits)

1g291 / Q9YGA6 Malk (see paper)
    46% identity, 72% coverage of query (223 bits)

MALK_THELN / Q9YGA6 Trehalose/maltose import ATP-binding protein MalK; EC 7.5.2.1 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 5 papers)
    46% identity, 72% coverage of query (222 bits)

Q8NMV1 ABC-type maltose transporter (EC 7.5.2.1) from Corynebacterium glutamicum (see paper)
TC 3.A.1.1.45 / Q8NMV1 ABC-type sugar transport system, ATPase component, component of Maltose transporter, MusEFGKI from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
    40% identity, 79% coverage of query (221 bits)

YdcT / b1441 putative ABC transporter ATP-binding protein YdcT from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ydcT / P77795 putative ABC transporter ATP-binding protein YdcT from Escherichia coli (strain K12) (see 3 papers)
YDCT_ECOLI / P77795 Uncharacterized ABC transporter ATP-binding protein YdcT from Escherichia coli (strain K12) (see paper)
    41% identity, 90% coverage of query (221 bits)

PfGW456L13_1897 ABC transporter for D-Galactose and D-Glucose, ATPase component from Pseudomonas fluorescens GW456-L13
    40% identity, 83% coverage of query (221 bits)

PS417_22130 glucose/xylose ABC transporter, ATPase component from Pseudomonas simiae WCS417
    38% identity, 93% coverage of query (221 bits)

8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
    41% identity, 78% coverage of query (219 bits)

8hprD Lpqy-sugabc in state 4
    41% identity, 78% coverage of query (219 bits)

8hprC Lpqy-sugabc in state 4
    41% identity, 78% coverage of query (219 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    38% identity, 87% coverage of query (213 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    38% identity, 87% coverage of query (213 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    38% identity, 87% coverage of query (213 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    38% identity, 87% coverage of query (213 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    38% identity, 87% coverage of query (213 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    38% identity, 87% coverage of query (213 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    39% identity, 81% coverage of query (213 bits)

1q12A Crystal structure of the atp-bound e. Coli malk
    38% identity, 87% coverage of query (213 bits)

1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
    41% identity, 79% coverage of query (211 bits)

sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
    43% identity, 71% coverage of query (209 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    37% identity, 80% coverage of query (199 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    37% identity, 80% coverage of query (199 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    37% identity, 80% coverage of query (199 bits)

2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    38% identity, 81% coverage of query (190 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    36% identity, 75% coverage of query (184 bits)

3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
    37% identity, 87% coverage of query (165 bits)

2awnA / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    31% identity, 87% coverage of query (151 bits)

Build an alignment

Build an alignment for WP_012590119.1 and 39 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

7tbwA / O95477 The structure of atp-bound abca1 (see paper)
    22% identity, 70% coverage of query (67.4 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory