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Searching for up to 100 curated homologs for WP_012590207.1 NCBI__GCF_000021745.1:WP_012590207.1 (337 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

LPSL_RHIME / O54067 Probable UDP-glucuronate 4-epimerase; UDP-glucuronic acid epimerase; EC 5.1.3.6 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
    57% identity, 99% coverage of query (393 bits)

UGA4E_RHIR8 / B9J8R3 UDP-glucuronate 4-epimerase; UGA4E; ArUGAE; EC 5.1.3.6 from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter)
    58% identity, 98% coverage of query (380 bits)

5u4qA 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
    51% identity, 99% coverage of query (328 bits)

5u4qB 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
    49% identity, 99% coverage of query (298 bits)

GAE4 / O22141 subunit of UDP-GlcA 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
GAE4_ARATH / O22141 UDP-glucuronate 4-epimerase 4; UDP-glucuronic acid epimerase 4; AtUGlcAE1; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O22141 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 4 papers)
    43% identity, 99% coverage of query (285 bits)

GAE1_ARATH / Q9M0B6 UDP-glucuronate 4-epimerase 1; UDP-glucuronic acid epimerase 1; AtUGlcAE3; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9M0B6 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 3 papers)
    44% identity, 99% coverage of query (281 bits)

GAE2_ARATH / Q9LPC1 UDP-glucuronate 4-epimerase 2; UDP-glucuronic acid epimerase 2; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LPC1 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
    44% identity, 100% coverage of query (280 bits)

Q304Y2 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Zea mays (see paper)
    44% identity, 99% coverage of query (279 bits)

Q6K9M5 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Oryza sativa (see paper)
    43% identity, 99% coverage of query (278 bits)

GAE3_ARATH / O81312 UDP-glucuronate 4-epimerase 3; UDP-glucuronic acid epimerase 3; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
O81312 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
    44% identity, 98% coverage of query (277 bits)

GAE6_ARATH / Q9LIS3 UDP-glucuronate 4-epimerase 6; UDP-glucuronic acid epimerase 6; AtUGlcAE2; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9LIS3 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 3 papers)
    41% identity, 100% coverage of query (265 bits)

GAE5_ARATH / Q9STI6 UDP-glucuronate 4-epimerase 5; UDP-glucuronic acid epimerase 5; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9STI6 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 2 papers)
    41% identity, 99% coverage of query (251 bits)

gla / P96481 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Streptococcus pneumoniae (see 2 papers)
    38% identity, 98% coverage of query (251 bits)

A0A1J0KK43 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Albuca bracteata (see paper)
    42% identity, 98% coverage of query (246 bits)

UGA4E_THEGP / F8C4X8 UDP-glucuronate 4-epimerase; UGA4E; TgUGAE; EC 5.1.3.6 from Thermodesulfobacterium geofontis (strain OPF15)
    39% identity, 97% coverage of query (239 bits)

6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
    32% identity, 99% coverage of query (159 bits)

6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
    32% identity, 99% coverage of query (159 bits)

6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
    32% identity, 99% coverage of query (159 bits)

6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
    32% identity, 99% coverage of query (158 bits)

A3MUJ4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrobaculum calidifontis (see paper)
    31% identity, 96% coverage of query (129 bits)

6kv9A / A0A003 Moee5 in complex with udp-glucuronic acid and NAD (see paper)
    32% identity, 99% coverage of query (126 bits)

Build an alignment

Build an alignment for WP_012590207.1 and 21 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
    29% identity, 99% coverage of query (125 bits)

6kvcA Moee5 in complex with udp-glucose and NAD
    32% identity, 99% coverage of query (124 bits)

UGE1_PEA / B0M3E8 Bifunctional UDP-glucose 4-epimerase and UDP-xylose 4-epimerase 1; UDP-D-xylose 4-epimerase; UDP-L-arabinose 4-epimerase; UDP-galactose 4-epimerase 1; UDP-glucose 4-epimerase 1; PsUGE1; EC 5.1.3.2; EC 5.1.3.5 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see paper)
B0M3E8 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-arabinose 4-epimerase (EC 5.1.3.5) from Pisum sativum (see paper)
    29% identity, 99% coverage of query (117 bits)

3aw9A / A3MUJ4 Structure of udp-galactose 4-epimerase mutant
    30% identity, 96% coverage of query (115 bits)

6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
    30% identity, 96% coverage of query (115 bits)

6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
    30% identity, 96% coverage of query (115 bits)

TGDS_HUMAN / O95455 dTDP-D-glucose 4,6-dehydratase; EC 4.2.1.46 from Homo sapiens (Human) (see paper)
    27% identity, 98% coverage of query (111 bits)

1hzjA Human udp-galactose 4-epimerase: accommodation of udp-n- acetylglucosamine within the active site
    28% identity, 98% coverage of query (109 bits)

UGE5_ARATH / Q9SN58 UDP-glucose 4-epimerase 5; AtUGE5; UDP-galactose 4-epimerase 5; EC 5.1.3.2 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9SN58 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 2 papers)
    27% identity, 97% coverage of query (108 bits)

2b69A / Q8NBZ7 Crystal structure of human udp-glucoronic acid decarboxylase
    27% identity, 100% coverage of query (108 bits)

UXS1_RAT / Q5PQX0 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Rattus norvegicus (Rat) (see paper)
    27% identity, 100% coverage of query (108 bits)

UXS1_HUMAN / Q8NBZ7 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; hUXS; hUXS1; EC 4.1.1.35 from Homo sapiens (Human) (see 3 papers)
    27% identity, 100% coverage of query (108 bits)

O64749 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see paper)
    29% identity, 98% coverage of query (108 bits)

8wovB / Q9T0A7 Crystal structure of arabidopsis thaliana udp-glucose 4-epimerase 2 (atuge2) complexed with udp, g233a mutant (see paper)
    27% identity, 97% coverage of query (108 bits)

UGE2_ARATH / Q9T0A7 UDP-glucose 4-epimerase 2; AtUGE2; UDP-galactose 4-epimerase 2; EC 5.1.3.2 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9T0A7 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 2 papers)
    27% identity, 97% coverage of query (107 bits)

1i3kA / Q14376 Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase (see paper)
    28% identity, 98% coverage of query (107 bits)

GALE / Q14376 UDP-galactose 4-epimerase (EC 5.1.3.2; EC 5.1.3.7) from Homo sapiens (see 6 papers)
GALE_HUMAN / Q14376 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Homo sapiens (Human) (see 12 papers)
Q14376 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Homo sapiens (see 4 papers)
    28% identity, 98% coverage of query (107 bits)

Q2LC81 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Hordeum vulgare (see paper)
    28% identity, 98% coverage of query (107 bits)

6bwlA / Q3ESA4 X-ray structure of pal from bacillus thuringiensis (see paper)
    28% identity, 99% coverage of query (107 bits)

1i3lA Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase
    28% identity, 98% coverage of query (107 bits)

1ek6A Structure of human udp-galactose 4-epimerase complexed with nadh and udp-glucose
    28% identity, 98% coverage of query (107 bits)

UGE1 / Q42605 UDP-D-glucose/UDP-D-galactose 4-epimerase subunit (EC 5.1.3.2) from Arabidopsis thaliana (see 2 papers)
UGE1_ARATH / Q42605 Bifunctional UDP-glucose 4-epimerase and UDP-xylose 4-epimerase 1; UDP-D-xylose 4-epimerase; UDP-L-arabinose 4-epimerase; UDP-galactose 4-epimerase 1; UDP-glucose 4-epimerase 1; AtUGE1; EC 5.1.3.2; EC 5.1.3.5 from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
Q42605 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 2 papers)
    28% identity, 97% coverage of query (105 bits)

3vpsA / E5KJ94 Structure of a novel NAD dependent-ndp-hexosamine 5,6-dehydratase, tuna, involved in tunicamycin biosynthesis
    27% identity, 98% coverage of query (104 bits)

Q9FI17 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see paper)
    27% identity, 98% coverage of query (103 bits)

tunA / E5KJ94 UDP-N-acetyl-α-D-glucosamine 5,6-dehydratase from Streptomyces chartreusis (see paper)
    27% identity, 98% coverage of query (103 bits)

Q8KN66 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Pseudomonas aeruginosa (see paper)
1sb8A / Q8KN66 Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-n-acetylgalactosamine (see paper)
    27% identity, 97% coverage of query (102 bits)

1udaA Structure of udp-galactose-4-epimerase complexed with udp-4-deoxy-4- fluoro-alpha-d-galactose
    25% identity, 99% coverage of query (102 bits)

1naiA Udp-galactose 4-epimerase from escherichia coli, oxidized
    25% identity, 99% coverage of query (102 bits)

1lrjA Crystal structure of e. Coli udp-galactose 4-epimerase complexed with udp-n-acetylglucosamine
    25% identity, 99% coverage of query (102 bits)

1sb9A Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-glucose
    27% identity, 97% coverage of query (102 bits)

UGE3_ARATH / Q8LDN8 Bifunctional UDP-glucose 4-epimerase and UDP-xylose 4-epimerase 3; UDP-D-xylose 4-epimerase; UDP-L-arabinose 4-epimerase; UDP-galactose 4-epimerase 3; UDP-glucose 4-epimerase 3; AtUGE3; EC 5.1.3.2; EC 5.1.3.5 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q8LDN8 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 2 papers)
    27% identity, 97% coverage of query (101 bits)

7kn1A / B2FNY6 Crystal structure of udp-glucose-4-epimerase (gale) from stenotrophomonas maltophila with bound NAD and formylated udp- arabinopyranose
    27% identity, 99% coverage of query (100 bits)

Q9SUN3 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see paper)
    27% identity, 98% coverage of query (100 bits)

GalD / b0759 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
galE / P09147 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli (strain K12) (see 38 papers)
GALE_ECOLI / P09147 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Escherichia coli (strain K12) (see 13 papers)
    25% identity, 99% coverage of query (100 bits)

UXS1_DANRE / Q6GMI9 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UXS-1; EC 4.1.1.35 from Danio rerio (Zebrafish) (Brachydanio rerio) (see 3 papers)
    26% identity, 100% coverage of query (100 bits)

2udpA Udp-galactose 4-epimerase complexed with udp-phenol
    25% identity, 99% coverage of query (100 bits)

1udcA Structure of udp-galactose-4-epimerase complexed with udp-mannose
    25% identity, 99% coverage of query (100 bits)

wbpP / Q9RHD6 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Pseudomonas aeruginosa (see 8 papers)
    27% identity, 97% coverage of query (99.8 bits)

Q2LC83 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Hordeum vulgare (see paper)
    28% identity, 98% coverage of query (99.8 bits)

1kvrA Udp-galactose 4-epimerase complexed with udp-phenol
    25% identity, 99% coverage of query (99.8 bits)

jadT / Q939Q5 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
    29% identity, 76% coverage of query (99.4 bits)

UGE4_ARATH / Q9C7W7 UDP-glucose 4-epimerase 4; AtUGE4; Protein ROOT EPIDERMAL BULGER 1; Protein ROOT HAIR DEFECTIVE 1; UDP-galactose 4-epimerase 4; EC 5.1.3.2 from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
Q9C7W7 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 3 papers)
    27% identity, 90% coverage of query (99.4 bits)

GI|1143392 uridine diphosphate glucose epimerase; EC 5.1.3.2 from Arabidopsis thaliana (see 2 papers)
CAA90941.1 uridine diphosphate glucose epimerase from Arabidopsis thaliana (see 2 papers)
    27% identity, 97% coverage of query (99.4 bits)

UAE / Q868I5 UDP-N-acetylglucosamine 4'-epimerase (EC 5.1.3.7) from Giardia intestinalis (see 7 papers)
    27% identity, 97% coverage of query (99.4 bits)

UXS1 / Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
UXS1_ARATH / Q8VZC0 UDP-glucuronic acid decarboxylase 1; UDP-XYL synthase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
    30% identity, 72% coverage of query (98.6 bits)

1a9yA / P09147 Udp-galactose 4-epimerase mutant s124a/y149f complexed with udp- glucose (see paper)
    25% identity, 99% coverage of query (98.2 bits)

7ystA / P9WN67 Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chain b from mycobacterium tuberculosis
    28% identity, 98% coverage of query (98.2 bits)

3lu1A / Q7BJX9 Crystal structure analysis of wbgu: a udp-galnac 4-epimerase (see paper)
    27% identity, 98% coverage of query (98.2 bits)

galE1 / P9WN67 UDP-galactose/glucose 4-epimerase subunit (EC 5.1.3.7; EC 5.1.3.2) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WN67 UDP-glucose 4-epimerase (EC 5.1.3.2) from Mycobacterium tuberculosis (see paper)
    28% identity, 98% coverage of query (98.2 bits)

7ysmA Crystal structure of udp-glucose 4-epimerase (rv3634c) co-crystallized with udp-n-acetylglucosamine from mycobacterium tuberculosis
    29% identity, 98% coverage of query (98.2 bits)

7ys9A Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chaina from mycobacterium tuberculosis
    29% identity, 98% coverage of query (98.2 bits)

3ruhA Alternative analogs as viable substrates of udp-hexose 4-epimerases
    27% identity, 98% coverage of query (98.2 bits)

3rufA Alternative analogs as viable substrates of udp-hexose 4-epimerases
    27% identity, 98% coverage of query (98.2 bits)

uxs1 / Q92WA4 UDP-xylose synthase 1 subunit (EC 4.1.1.35) from Rhizobium meliloti (strain 1021) (see paper)
    27% identity, 96% coverage of query (97.8 bits)

tylA2 / Q54144 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces fradiae (see 2 papers)
    27% identity, 98% coverage of query (97.1 bits)

MUR4 / Q9SA77 UDP-D-xylose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 3 papers)
ARAE1_ARATH / Q9SA77 UDP-arabinose 4-epimerase 1; UDP-D-xylose 4-epimerase 1; EC 5.1.3.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9SA77 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see paper)
    27% identity, 98% coverage of query (97.1 bits)

wbgU / Q7BJX9 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Plesiomonas shigelloides (see paper)
GNE_PLESH / Q7BJX9 UDP-N-acetylglucosamine 4-epimerase; UDP-GalNAc 4-epimerase; EC 5.1.3.7 from Plesiomonas shigelloides (Aeromonas shigelloides) (see 3 papers)
Q7BJX9 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Plesiomonas shigelloides (see 2 papers)
    27% identity, 98% coverage of query (96.7 bits)

6pmhA Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
    27% identity, 80% coverage of query (96.3 bits)

6pnlA / O26475 Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
    27% identity, 80% coverage of query (95.9 bits)

4lk3B / Q8NBZ7 Crystal structure of human udp-xylose synthase r236a substitution (see paper)
    26% identity, 100% coverage of query (95.1 bits)

2hunA / O58151 Crystal structure of hypothetical protein ph0414 from pyrococcus horikoshii ot3
    27% identity, 98% coverage of query (94.4 bits)

7xpqA Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glcnac
    27% identity, 97% coverage of query (94.4 bits)

7xpoA / C0HI30 Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glc (see paper)
    27% identity, 97% coverage of query (94.0 bits)

1kewA The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from salmonella enterica serovar typhimurium with thymidine diphosphate bound
    24% identity, 98% coverage of query (94.0 bits)

RMLB_SALTY / P26391 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
1keuA / P26391 The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from salmonella enterica serovar typhimurium with dtdp-d-glucose bound (see paper)
rmlB / CAA40115.1 dTDP-glucose 4,6-dehydratase from Salmonella enterica (see 6 papers)
    24% identity, 98% coverage of query (94.0 bits)

8du1A / A0A077ELH2 Crystal structure of NAD bound dtdp-glucose 4,6-dehydratase from elizabethkingia anophelis
    24% identity, 97% coverage of query (94.0 bits)

1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
    26% identity, 98% coverage of query (93.6 bits)

6dntA / D3E402 Udp-n-acetylglucosamine 4-epimerase from methanobrevibacter ruminantium m1 in complex with udp-n-acetylmuramic acid (see paper)
    25% identity, 97% coverage of query (93.6 bits)

1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
    26% identity, 98% coverage of query (93.2 bits)

RHM2 / Q9LPG6 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM2 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM2_ARATH / Q9LPG6 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2; NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    26% identity, 97% coverage of query (92.8 bits)

4lk3C Crystal structure of human udp-xylose synthase r236a substitution
    26% identity, 100% coverage of query (92.4 bits)

GALE_CAEEL / Q564Q1 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Caenorhabditis elegans (see paper)
    25% identity, 98% coverage of query (91.3 bits)

8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
    25% identity, 97% coverage of query (89.4 bits)

RHM1 / Q9SYM5 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM1 (EC 4.2.1.76) from Arabidopsis thaliana (see 3 papers)
RHM1_ARATH / Q9SYM5 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1; Protein REPRESSOR OF LRX1 1; Rhamnose biosynthetic enzyme 1; AtRHM1; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
    26% identity, 97% coverage of query (88.2 bits)

2c20A / A0A6L8PTV5 Crystal structure of udp-glucose 4-epimerase
    26% identity, 93% coverage of query (85.5 bits)

2p5uA / Q5SKQ2 Crystal structure of thermus thermophilus hb8 udp-glucose 4-epimerase complex with NAD
    29% identity, 97% coverage of query (85.1 bits)

8sk0B / A0A1C5ADV9 Crystal structure of evds6 decarboxylase in ligand bound state (see paper)
    26% identity, 98% coverage of query (83.2 bits)

8sk0A Crystal structure of evds6 decarboxylase in ligand bound state
    25% identity, 98% coverage of query (82.8 bits)

3enkA / Q3JPI3 1.9a crystal structure of udp-glucose 4-epimerase from burkholderia pseudomallei
    30% identity, 93% coverage of query (82.8 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory