Searching for up to 100 curated homologs for WP_012590395.1 NCBI__GCF_000021745.1:WP_012590395.1 (1147 a.a.)
Found high-coverage hits (≥70%) to 39 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q2K340 pyruvate carboxylase (EC 6.4.1.1) from Rhizobium etli (see 8 papers)
70% identity, 100% coverage of query (1649 bits)
3tw6B / Q2K340 Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a (see paper)
69% identity, 99% coverage of query (1602 bits)
3tw6C Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a
70% identity, 92% coverage of query (1504 bits)
2qf7A / Q2K340 Crystal structure of a complete multifunctional pyruvate carboxylase from rhizobium etli (see paper)
65% identity, 100% coverage of query (1493 bits)
2qf7B / Q2K340 Crystal structure of a complete multifunctional pyruvate carboxylase from rhizobium etli (see paper)
68% identity, 92% coverage of query (1458 bits)
3tw6A Structure of rhizobium etli pyruvate carboxylase t882a with the allosteric activator, acetyl coenzyme-a
66% identity, 93% coverage of query (1423 bits)
PYC_BACSU / Q9KWU4 Pyruvate carboxylase; Pyruvic carboxylase; PYC; EC 6.4.1.1 from Bacillus subtilis (strain 168) (see 2 papers)
52% identity, 100% coverage of query (1233 bits)
A1ANN6 biotin carboxylase (EC 6.3.4.14) from Pelobacter propionicus (see paper)
52% identity, 100% coverage of query (1207 bits)
A5G5L1 biotin carboxylase (EC 6.3.4.14) from Geotalea uraniireducens (see paper)
54% identity, 100% coverage of query (1206 bits)
PYC_STAAM / A0A0H3JRU9 Pyruvate carboxylase; EC 6.4.1.1 from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see 3 papers)
A0A0H3JRU9 pyruvate carboxylase (EC 6.4.1.1) from Staphylococcus aureus (see 4 papers)
51% identity, 100% coverage of query (1190 bits)
3bg5A / A0A0H3JRU9 Crystal structure of staphylococcus aureus pyruvate carboxylase (see paper)
50% identity, 100% coverage of query (1165 bits)
3hb9A Crystal structure of s. Aureus pyruvate carboxylase a610t mutant
50% identity, 100% coverage of query (1154 bits)
5vyzA Crystal structure of lactococcus lactis pyruvate carboxylase in complex with cyclic-di-amp (see paper)
49% identity, 100% coverage of query (1127 bits)
7zz3A Cryo-em structure of "bc react" conformation of lactococcus lactis pyruvate carboxylase with acetyl-coa
49% identity, 100% coverage of query (1125 bits)
PYC1_CAEEL / O17732 Pyruvate carboxylase 1; Pyruvic carboxylase 1; PCB 1; EC 6.4.1.1 from Caenorhabditis elegans (see paper)
O17732 pyruvate carboxylase (EC 6.4.1.1) from Caenorhabditis elegans (see paper)
49% identity, 100% coverage of query (1078 bits)
7zyyA Cryo-em structure of lactococcus lactis pyruvate carboxylase with acetyl-coa
50% identity, 92% coverage of query (1059 bits)
8gk8A R21a staphylococcus aureus pyruvate carboxylase
50% identity, 92% coverage of query (1058 bits)
PC / P11498 pyruvate carboxylase, mitochondrial (EC 6.4.1.1) from Homo sapiens (see 5 papers)
PYC_HUMAN / P11498 Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase; PCB; EC 6.4.1.1 from Homo sapiens (Human) (see 5 papers)
P11498 pyruvate carboxylase (EC 6.4.1.1) from Homo sapiens (see 5 papers)
48% identity, 100% coverage of query (1055 bits)
7wtbB / P11498 Cryo-em structure of human pyruvate carboxylase with acetyl-coa (see paper)
48% identity, 100% coverage of query (1055 bits)
7wtdC Cryo-em structure of human pyruvate carboxylase with acetyl-coa in the intermediate state 1
48% identity, 100% coverage of query (1055 bits)
Q29RK2 pyruvate carboxylase (EC 6.4.1.1) from Bos taurus (see paper)
48% identity, 100% coverage of query (1044 bits)
PYC2_YEAST / P32327 Pyruvate carboxylase 2; Pyruvic carboxylase 2; PCB 2; EC 6.4.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P32327 pyruvate carboxylase (EC 6.4.1.1) from Saccharomyces cerevisiae (see paper)
47% identity, 100% coverage of query (1041 bits)
pycA putative pyruvate carboxylase or glutathione synthase from Emericella nidulans (see paper)
47% identity, 100% coverage of query (1041 bits)
PYC / O93918 pyruvate carboxylase monomer (EC 6.4.1.1) from Aspergillus terreus (see paper)
47% identity, 100% coverage of query (1032 bits)
PYC_MOUSE / Q05920 Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase; PCB; EC 6.4.1.1 from Mus musculus (Mouse) (see paper)
47% identity, 100% coverage of query (1032 bits)
pyr1 / RF|NP_595900.1 pyruvate carboxylase Pyr1; EC 6.4.1.1 from Schizosaccharomyces pombe (see paper)
46% identity, 100% coverage of query (1029 bits)
PYC1_YEAST / P11154 Pyruvate carboxylase 1; Pyruvic carboxylase 1; PCB 1; EC 6.4.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P11154 pyruvate carboxylase (EC 6.4.1.1) from Saccharomyces cerevisiae (see 2 papers)
47% identity, 100% coverage of query (1021 bits)
A0QV14 pyruvate carboxylase (EC 6.4.1.1) from Mycolicibacterium smegmatis (see paper)
50% identity, 100% coverage of query (988 bits)
pycA / Q9F843 pyruvate carboxylase subunit (EC 6.4.1.1) from Mycolicibacterium smegmatis (see paper)
50% identity, 100% coverage of query (986 bits)
4qshC Crystal structure of l. Monocytogenes pyruvate carboxylase in complex with cyclic-di-amp (see paper)
50% identity, 82% coverage of query (983 bits)
B9X0T8 pyruvate carboxylase (EC 6.4.1.1) from Emiliania huxleyi (see paper)
47% identity, 99% coverage of query (978 bits)
3bg5B / A0A0H3JRU9 Crystal structure of staphylococcus aureus pyruvate carboxylase (see paper)
50% identity, 82% coverage of query (965 bits)
5vyzC Crystal structure of lactococcus lactis pyruvate carboxylase in complex with cyclic-di-amp (see paper)
49% identity, 82% coverage of query (942 bits)
8gk8C R21a staphylococcus aureus pyruvate carboxylase
51% identity, 74% coverage of query (902 bits)
3ho8A Crystal structure of s. Aureus pyruvate carboxylase in complex with coenzyme a
50% identity, 75% coverage of query (901 bits)
4hnvB / A0A0H3JRU9 Crystal structure of r54e mutant of s. Aureus pyruvate carboxylase (see paper)
48% identity, 82% coverage of query (900 bits)
5vywA Crystal structure of lactococcus lactis pyruvate carboxylase
50% identity, 74% coverage of query (870 bits)
3ho8D / A0A0H3JRU9 Crystal structure of s. Aureus pyruvate carboxylase in complex with coenzyme a (see paper)
47% identity, 74% coverage of query (811 bits)
8gk8D R21a staphylococcus aureus pyruvate carboxylase
48% identity, 74% coverage of query (809 bits)
Build an alignment for WP_012590395.1 and 39 homologs with ≥ 30% identity
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Lawrence Berkeley National Laboratory