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Searching for up to 100 curated homologs for WP_012592214.1 NCBI__GCF_000021745.1:WP_012592214.1 (431 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

A0R5R7 Putative aminotransferase MSMEG_6286/MSMEI_6121 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    53% identity, 94% coverage of query (450 bits)

ASPAT_MYCTU / O69689 Aspartate aminotransferase; AspAT; EC 2.6.1.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
O69689 aspartate transaminase (EC 2.6.1.1) from Mycobacterium tuberculosis (see paper)
    51% identity, 99% coverage of query (439 bits)

6u7aD / O69689 Rv3722c in complex with kynurenine (see paper)
    51% identity, 99% coverage of query (438 bits)

5c6uA Rv3722c aminotransferase from mycobacterium tuberculosis
    52% identity, 98% coverage of query (436 bits)

6u78B Rv3722c in complex with glutamic acid
    52% identity, 97% coverage of query (436 bits)

6u7aA Rv3722c in complex with kynurenine
    52% identity, 97% coverage of query (436 bits)

ASPAT_CORGL / Q8NTR2 Aspartate aminotransferase; AspAT; EC 2.6.1.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
Q8NTR2 aspartate transaminase (EC 2.6.1.1) from Corynebacterium glutamicum (see paper)
    49% identity, 95% coverage of query (426 bits)

5hxxA / Q8NTR2 Crystal structure of aspat from corynebacterium glutamicum
    49% identity, 95% coverage of query (425 bits)

3pplA Crystal structure of an aspartate transaminase (ncgl0237, cgl0240) from corynebacterium glutamicum atcc 13032 kitasato at 1.25 a resolution
    49% identity, 95% coverage of query (425 bits)

5iwqB Crystal structure of aspartate aminotransferase (aspat) from corynebacterium glutamicum atcc 13032
    49% identity, 95% coverage of query (425 bits)

Build an alignment

Build an alignment for WP_012592214.1 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

3cbfA Crystal structure of lysn, alpha-aminoadipate aminotransferase, from thermus thermophilus hb27
    26% identity, 77% coverage of query (84.0 bits)

2egyA Crystal structure of lysn, alpha-aminoadipate aminotransferase (substrate free form), from thermus thermophilus hb27
    26% identity, 77% coverage of query (84.0 bits)

LYSN_THET2 / Q72LL6 2-aminoadipate transaminase; 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT; EC 2.6.1.39 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 3 papers)
Q72LL6 2-aminoadipate transaminase (EC 2.6.1.39) from Thermus thermophilus (see paper)
2zyjA / Q72LL6 Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-glutamate), from thermus thermophilus hb27 (see paper)
    26% identity, 77% coverage of query (83.6 bits)

lysN / Q5SL82 L-2-aminoadipate aminotransferase monomer (EC 2.6.1.39) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    26% identity, 77% coverage of query (83.6 bits)

2z1yA Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-leucine), from thermus thermophilus hb27
    26% identity, 77% coverage of query (83.6 bits)

tdiD putative aminotransferase from Emericella nidulans (see paper)
    23% identity, 79% coverage of query (55.8 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory