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Searching for up to 100 curated homologs for WP_012646712.1 NCBI__GCF_000022265.1:WP_012646712.1 (333 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

O52593 phosphate acetyltransferase (EC 2.3.1.8) from Acetivibrio thermocellus (see paper)
    54% identity, 100% coverage of query (351 bits)

pta / P71103 phosphate acetyltransferase (EC 2.3.1.8) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see paper)
    51% identity, 100% coverage of query (332 bits)

B2RK03 phosphate acetyltransferase (EC 2.3.1.8) from Porphyromonas gingivalis (see paper)
    52% identity, 99% coverage of query (330 bits)

6ioxA / B2RK03 Crystal structure of porphyromonas gingivalis phosphotransacetylase in complex with acetyl-coa (see paper)
    52% identity, 99% coverage of query (328 bits)

2af3C / P38503 Phosphotransacetylase from methanosarcina thermophila soaked with coenzyme a (see paper)
    48% identity, 99% coverage of query (299 bits)

PTAS_METTE / P38503 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Methanosarcina thermophila (see paper)
pta / AAA72041.1 phosphotransacetylase from Methanosarcina thermophila (see paper)
    48% identity, 99% coverage of query (299 bits)

PTAS_CORGL / P77844 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 3 papers)
    47% identity, 97% coverage of query (288 bits)

1xcoD / P39646 Crystal structure of a phosphotransacetylase from bacillus subtilis in complex with acetylphosphate (see paper)
    47% identity, 94% coverage of query (268 bits)

PAT2 / A8IZZ9 phosphate acetyltransferase (EC 2.3.1.8) from Chlamydomonas reinhardtii (see 3 papers)
    45% identity, 98% coverage of query (264 bits)

pta / Q9F1X6 phosphotransacetylase (EC 2.3.1.8) from Fructilactobacillus sanfranciscensis (see paper)
    43% identity, 99% coverage of query (259 bits)

PTA_SALTY / Q8ZND6 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.222; EC 2.3.1.8 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
Q8ZND6 phosphate acetyltransferase (EC 2.3.1.8) from Salmonella enterica (see paper)
    45% identity, 98% coverage of query (258 bits)

Pta / b2297 phosphate acetyltransferase (EC 2.3.1.8; EC 2.3.1.222) from Escherichia coli K-12 substr. MG1655 (see 28 papers)
pta / P0A9M8 phosphate acetyltransferase (EC 2.3.1.8; EC 2.3.1.222) from Escherichia coli (strain K12) (see 25 papers)
PTA_ECOLI / P0A9M8 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Escherichia coli (strain K12) (see 5 papers)
P0A9M8 phosphate acetyltransferase (EC 2.3.1.8) from Escherichia coli (see paper)
pta phosphate acetyltransferase from Escherichia coli K12 (see paper)
    44% identity, 98% coverage of query (257 bits)

C1DQG8 phosphate acetyltransferase (EC 2.3.1.8) from Azotobacter vinelandii (see 2 papers)
    46% identity, 98% coverage of query (256 bits)

PTA_PSEAE / Q9I5A5 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    45% identity, 98% coverage of query (250 bits)

C1DER7 phosphate acetyltransferase (EC 2.3.1.8) from Azotobacter vinelandii (see 2 papers)
    44% identity, 97% coverage of query (249 bits)

pta / A3SR26 phosphate acetyltransferase (EC 2.3.1.8) from Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM) (see paper)
    44% identity, 95% coverage of query (248 bits)

YpfA / b2458 phosphate acetyltransferase EutD (EC 2.3.1.8) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
eutD / P77218 phosphate acetyltransferase EutD (EC 2.3.1.8) from Escherichia coli (strain K12) (see 3 papers)
EUTD_ECOLI / P77218 Phosphate acetyltransferase EutD; Ethanolamine utilization protein EutD; EC 2.3.1.8 from Escherichia coli (strain K12) (see paper)
eutD / RF|NP_416953 ethanolamine utilization protein eutD from Escherichia coli K12 (see paper)
    44% identity, 99% coverage of query (248 bits)

Q5LMK3 phosphate acetyltransferase (EC 2.3.1.8) from Ruegeria pomeroyi (see paper)
    45% identity, 95% coverage of query (241 bits)

EUTD_SALTY / P41790 Phosphate acetyltransferase EutD; Ethanolamine utilization protein EutD; Phosphotransacetylase EutD; PATC EutD; EC 2.3.1.8 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 8 papers)
P41790 phosphate acetyltransferase (EC 2.3.1.8) from Salmonella enterica (see paper)
    40% identity, 99% coverage of query (237 bits)

6zngF / Q6MM14,Q6MM15 Maeb full-length acetyl-coa bound state (see paper)
    37% identity, 95% coverage of query (187 bits)

pta / P75359 phosphate acetyltransferase (EC 2.3.1.8) from Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (see 2 papers)
    37% identity, 98% coverage of query (181 bits)

YpfF / b2463 NADP+-dependent malate dehydrogenase (EC 1.1.1.40) from Escherichia coli K-12 substr. MG1655 (see paper)
maeB / P76558 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) (EC 1.1.1.40; EC 4.1.1.101) from Escherichia coli (strain K12) (see 22 papers)
MAO2_ECOLI / P76558 NADP-dependent malic enzyme; NADP-ME; EC 1.1.1.40 from Escherichia coli (strain K12) (see 2 papers)
P76558 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) (EC 1.1.1.40) from Escherichia coli (see paper)
GB|AAC75516.1 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); EC 1.1.1.40 from Escherichia coli K12 (see 2 papers)
    35% identity, 99% coverage of query (174 bits)

Build an alignment

Build an alignment for WP_012646712.1 and 22 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

dme / GI|2582193 malate dehydrogenase (decarboxylating); EC 1.1.1.39 from Sinorhizobium meliloti (see 3 papers)
    29% identity, 94% coverage of query (144 bits)

A4F2S6 malate dehydrogenase (decarboxylating) (EC 1.1.1.39) from Rhodopseudomonas palustris (see paper)
    30% identity, 99% coverage of query (138 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory