Searching for up to 100 curated homologs for WP_012673760.1 NCBI__GCF_000021545.1:WP_012673760.1 (427 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
3bs8A / P30949 Crystal structure of glutamate 1-semialdehyde aminotransferase complexed with pyridoxamine-5'-phosphate from bacillus subtilis (see paper)
64% identity, 98% coverage of query (559 bits)
P30949 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Bacillus subtilis (see paper)
hemL / AAA22515.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus subtilis (see 2 papers)
64% identity, 98% coverage of query (558 bits)
hemL / CAD48149.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus megaterium (see paper)
63% identity, 99% coverage of query (541 bits)
3k28A / Q81LD0 Crystal structure of a glutamate-1-semialdehyde aminotransferase from bacillus anthracis with bound pyridoxal 5'phosphate
62% identity, 96% coverage of query (519 bits)
2e7uA / Q5SJS4 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from thermus thermophilus hb8
59% identity, 98% coverage of query (499 bits)
GSA2_ARATH / Q42522 Glutamate-1-semialdehyde 2,1-aminomutase 2, chloroplastic; GSA 2; Glutamate-1-semialdehyde aminotransferase 2; GSA-AT 2; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
56% identity, 100% coverage of query (493 bits)
P24630 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Synechococcus sp. (see 2 papers)
57% identity, 99% coverage of query (492 bits)
2gsaB Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
57% identity, 99% coverage of query (491 bits)
2gsaA Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
57% identity, 99% coverage of query (491 bits)
3fq7A / P24630 Gabaculine complex of gsam (see paper)
56% identity, 99% coverage of query (490 bits)
3usfA Crystal structure of dava-4
56% identity, 99% coverage of query (490 bits)
2hp2A Inter-subunit signaling in gsam
56% identity, 99% coverage of query (490 bits)
2hp1A Inter-subunit signaling in gsam
56% identity, 99% coverage of query (490 bits)
2hozA Inter-subunit signaling in gsam
56% identity, 99% coverage of query (490 bits)
GSA1 / P42799 glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
GSA1_ARATH / P42799 Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic; AtGSA1; GSA 1; Glutamate-1-semialdehyde aminotransferase 1; GSA-AT 1; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
P42799 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
55% identity, 98% coverage of query (489 bits)
3fqaA Gabaculien complex of gabaculine resistant gsam version
56% identity, 99% coverage of query (489 bits)
5hdmA / P42799 Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase (see paper)
55% identity, 99% coverage of query (488 bits)
5hdmB Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase
55% identity, 99% coverage of query (488 bits)
Gsa / b0154 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
hemL / P23893 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli (strain K12) (see 19 papers)
GSA_ECOLI / P23893 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Escherichia coli (strain K12) (see 3 papers)
53% identity, 99% coverage of query (473 bits)
hemL / P0CL07 glutamate-1-semialdehyde 2,1-aminomutase subunit (EC 5.4.3.8) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
53% identity, 99% coverage of query (471 bits)
6w80A / B2FT35 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from stenotrophomonas maltophilia k279a in complex with plp
56% identity, 98% coverage of query (470 bits)
5i92F / P48247 Crystal structure of glutamate-1-semialdehyde 2,1- aminomutase (gsa) from pseudomonas aeruginosa
52% identity, 98% coverage of query (450 bits)
3usfB / Q31QJ2 Crystal structure of dava-4
53% identity, 99% coverage of query (446 bits)
2hp1B Inter-subunit signaling in gsam
53% identity, 99% coverage of query (441 bits)
Q8NT73 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Corynebacterium glutamicum (see paper)
50% identity, 98% coverage of query (410 bits)
hemL / BAA21914.1 glutamate 1-semialdehyde 2,1-aminomutase from Propionibacterium freudenreichii (see 2 papers)
51% identity, 96% coverage of query (410 bits)
2cfbA / Q8DLK8 Glutamate-1-semialdehyde 2,1-aminomutase from thermosynechococcus elongatus (see paper)
52% identity, 92% coverage of query (401 bits)
GSA_SACS2 / Q980U5 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q980U5 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Saccharolobus solfataricus (see paper)
44% identity, 97% coverage of query (370 bits)
2zsmA / Q9Y9I9 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from aeropyrum pernix, hexagonal form
45% identity, 99% coverage of query (355 bits)
4zm4B / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
36% identity, 94% coverage of query (255 bits)
6k8hB / D1C218 Crystal structure of an omega-transaminase from sphaerobacter thermophilus (see paper)
37% identity, 92% coverage of query (251 bits)
D1C218 beta-alanine-pyruvate transaminase (EC 2.6.1.18) from Sphaerobacter thermophilus (see paper)
37% identity, 92% coverage of query (251 bits)
4zm4D / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
37% identity, 93% coverage of query (242 bits)
2ykuA / A3EYF7 Structural determinants of the beta-selectivity of a bacterial aminotransferase (see paper)
37% identity, 89% coverage of query (236 bits)
4ao4A Structural determinants of the beta-selectivity of a bacterial aminotransferase
37% identity, 89% coverage of query (236 bits)
2ykvA Structural determinants of the beta-selectivity of a bacterial aminotransferase
37% identity, 89% coverage of query (236 bits)
2ykyA Structural determinants of the beta-selectivity of a bacterial aminotransferase
37% identity, 89% coverage of query (235 bits)
2ykxA Structural determinants of the beta-selectivity of a bacterial aminotransferase
37% identity, 89% coverage of query (235 bits)
6ssdA Transaminase with plp bound (see paper)
36% identity, 91% coverage of query (231 bits)
6ssgA Transaminase with dcs bound
36% identity, 91% coverage of query (231 bits)
6ssfA Transaminase with lcs bound
36% identity, 91% coverage of query (231 bits)
6sseA Transaminase with pmp bound
36% identity, 91% coverage of query (231 bits)
KAT_CLOAI / B0VH76 3-aminobutyryl-CoA aminotransferase; HemL-like protein; EC 2.6.1.111 from Cloacimonas acidaminovorans (strain Evry) (see paper)
B0VH76 3-aminobutanoyl-CoA transaminase (EC 2.6.1.111) from Candidatus Cloacimonas acidaminovorans (see paper)
31% identity, 99% coverage of query (209 bits)
bmyA / CAE11250.1 BmyA protein from Bacillus amyloliquefaciens (see paper)
35% identity, 92% coverage of query (209 bits)
6kfuA / Q9R9J1 A acp-amt fusion protein of hybrid polyketide/non-ribosomal peptide synthetase
33% identity, 95% coverage of query (204 bits)
MYCA_BACIU / Q9R9J1 Mycosubtilin synthase subunit A; EC 2.3.1.- from Bacillus subtilis (see paper)
33% identity, 95% coverage of query (204 bits)
6kfrA Amino-transferase (amt) domain - arg complex of hybrid polyketide/non- ribosomal peptide synthetase
33% identity, 95% coverage of query (204 bits)
BFAT_VARPD / H8WR05 Beta-phenylalanine transaminase; Aromatic beta-amino acid aminotransferase; Beta-phenylalanine aminotransferase; VpAT; EC 2.6.1.- from Variovorax paradoxus (see paper)
H8WR05 tyrosine transaminase (EC 2.6.1.5) from Variovorax paradoxus (see paper)
33% identity, 89% coverage of query (201 bits)
4aoaA Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from variovorax paradoxus
33% identity, 89% coverage of query (201 bits)
4ao9A / H8WR05 Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from variovorax paradoxus (see paper)
33% identity, 89% coverage of query (200 bits)
dpgA / Q6VY99 D-phenylglycine aminotransferase monomer (EC 2.6.1.72) from Stutzerimonas stutzeri (see 7 papers)
Q6VY99 D-4-hydroxyphenylglycine transaminase (EC 2.6.1.72) from Pseudomonas stutzeri (see 2 papers)
35% identity, 77% coverage of query (177 bits)
gdnH / K4JEW9 guadinomine polyketide synthase module 4 from Streptomyces sp. K01-0509 (see paper)
31% identity, 91% coverage of query (174 bits)
YC7B_SCHPO / O94492 Uncharacterized aminotransferase C417.11c; EC 2.6.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 84% coverage of query (169 bits)
Build an alignment for WP_012673760.1 and 53 homologs with ≥ 30% identity
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fumI / D2D3B2 aminopentol aminotransferase from Sphingopyxis macrogoltabida (see paper)
FUMI_SPHMC / D2D3B2 Aminopentol aminotransferase; EC 2.6.1.- from Sphingopyxis macrogoltabida (Sphingomonas macrogoltabidus) (see 2 papers)
29% identity, 99% coverage of query (169 bits)
6hbvA / D2D3B2 Structure of plp internal aldimine form of sphingopyxis sp. Mta144 fumi protein
29% identity, 99% coverage of query (168 bits)
davT / Q9I6M4 5-aminovalerate aminotransferase (EC 2.6.1.48) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
DAVT_PSEAE / Q9I6M4 5-aminovalerate aminotransferase DavT; 5-aminovalerate transaminase; Delta-aminovalerate aminotransferase; EC 2.6.1.48 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I6M4 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas aeruginosa (see paper)
33% identity, 91% coverage of query (167 bits)
mxcL / Q9F631 myxocheline aldehyde aminotransferase from Stigmatella aurantiaca (see 2 papers)
27% identity, 100% coverage of query (164 bits)
1szkA The structure of gamma-aminobutyrate aminotransferase mutant: e211s
34% identity, 77% coverage of query (161 bits)
1sf2A / P22256 Structure of e. Coli gamma-aminobutyrate aminotransferase (see paper)
34% identity, 77% coverage of query (160 bits)
GabT / b2662 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655 (see 29 papers)
gabT / P22256 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli (strain K12) (see 28 papers)
GABT_ECOLI / P22256 4-aminobutyrate aminotransferase GabT; 5-aminovalerate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT; EC 2.6.1.19; EC 2.6.1.48 from Escherichia coli (strain K12) (see 6 papers)
34% identity, 77% coverage of query (160 bits)
1sffA Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate
34% identity, 77% coverage of query (160 bits)
Q5SHH5 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
36% identity, 71% coverage of query (158 bits)
lysJ / Q93R93 L-2-aminoadipate semialdehyde transaminase monomer (EC 2.6.1.118) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
LYSJ_THET2 / Q93R93 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
Q93R93 [amino group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase (EC 2.6.1.118) from Thermus thermophilus (see 2 papers)
36% identity, 71% coverage of query (157 bits)
1vefA / Q5SHH5 Acetylornithine aminotransferase from thermus thermophilus hb8
36% identity, 71% coverage of query (156 bits)
1wkhA Acetylornithine aminotransferase from thermus thermophilus hb8
36% identity, 71% coverage of query (156 bits)
1wkgA Acetylornithine aminotransferase from thermus thermophilus hb8
36% identity, 71% coverage of query (156 bits)
AO353_11510 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas fluorescens FW300-N2E3
34% identity, 76% coverage of query (154 bits)
Pf6N2E2_4013 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas fluorescens FW300-N2E2
34% identity, 76% coverage of query (154 bits)
gabT / Q4KKA1 4-aminobutyrate transaminase subunit (EC 2.6.1.19) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
34% identity, 76% coverage of query (154 bits)
dat / B0VCM6 diaminobutyrate—2-oxoglutarate transaminase monomer (EC 2.6.1.76) from Acinetobacter baumannii (strain AYE) (see 2 papers)
32% identity, 77% coverage of query (153 bits)
DAVT_PSEPK / Q88RB9 5-aminovalerate aminotransferase DavT; 5-aminovalerate transaminase; Delta-aminovalerate aminotransferase; EC 2.6.1.48 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
Q88RB9 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas putida (see 2 papers)
34% identity, 76% coverage of query (152 bits)
Q9HWU0 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Pseudomonas aeruginosa (see paper)
27% identity, 98% coverage of query (152 bits)
5yktA / Q9HWU0 Crystal structure of a glutamate-1-semialdehyde-aminomutase (k286a) from pseudomonas aeruginosa pao1 in complex with pmp (see paper)
26% identity, 98% coverage of query (150 bits)
BARAC_PYRHO / O57878 Broad substrate specificity amino-acid racemase; BAR; EC 5.1.1.10 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see 2 papers)
O57878 amino-acid racemase (EC 5.1.1.10) from Pyrococcus horikoshii (see 2 papers)
32% identity, 76% coverage of query (147 bits)
4addA Structural and functional study of succinyl-ornithine transaminase from e. Coli
34% identity, 76% coverage of query (146 bits)
4adbB / P77581 Structural and functional study of succinyl-ornithine transaminase from e. Coli (see paper)
34% identity, 76% coverage of query (146 bits)
A0QYS9 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
34% identity, 73% coverage of query (145 bits)
8cplC Yzw2 a scaffold for cryo-em of small proteins of interest
31% identity, 76% coverage of query (140 bits)
Q9X2A5 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
30% identity, 89% coverage of query (140 bits)
4uoxA Crystal structure of ygjg in complex with pyridoxal-5'-phosphate and putrescine
31% identity, 76% coverage of query (140 bits)
PatA / b3073 putrescine aminotransferase (EC 2.6.1.29) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
patA / P42588 putrescine aminotransferase (EC 2.6.1.82; EC 2.6.1.29) from Escherichia coli (strain K12) (see 15 papers)
PAT_ECOLI / P42588 Putrescine aminotransferase; PAT; PATase; Cadaverine transaminase; Diamine transaminase; Putrescine transaminase; Putrescine--2-oxoglutaric acid transaminase; Putrescine:2-OG aminotransferase; EC 2.6.1.82; EC 2.6.1.29 from Escherichia coli (strain K12) (see 8 papers)
P42588 putrescine-2-oxoglutarate transaminase (EC 2.6.1.82) from Escherichia coli (see 4 papers)
31% identity, 76% coverage of query (140 bits)
2ordA / Q9X2A5 Crystal structure of acetylornithine aminotransferase (ec 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution
30% identity, 89% coverage of query (140 bits)
4uoyA Crystal structure of ygjg in complex with pyridoxal-5'-phosphate
31% identity, 76% coverage of query (140 bits)
ARGD_SALTY / P40732 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
32% identity, 74% coverage of query (139 bits)
4jevB / P40732 N-acetylornithine aminotransferase from s. Typhimurium complexed with gabaculine
32% identity, 74% coverage of query (139 bits)
4jewA N-acetylornithine aminotransferase from s. Typhimurium complexed with l-canaline
32% identity, 74% coverage of query (138 bits)
2pb0A Structure of biosynthetic n-acetylornithine aminotransferase from salmonella typhimurium: studies on substrate specificity and inhibitor binding
32% identity, 74% coverage of query (137 bits)
5wyaA Structure of amino acid racemase, 2.65 a
30% identity, 72% coverage of query (131 bits)
4ysnC / M1GRN3 Structure of aminoacid racemase in complex with plp (see paper)
30% identity, 72% coverage of query (130 bits)
5wyfA Structure of amino acid racemase, 2.12 a
30% identity, 72% coverage of query (130 bits)
O66442 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Aquifex aeolicus (strain VF5)
30% identity, 72% coverage of query (130 bits)
2eh6A / O66442 Crystal structure of acetylornithine aminotransferase from aquifex aeolicus vf5
30% identity, 72% coverage of query (130 bits)
7lonA Ornithine aminotransferase (oat) cocrystallized with its inactivator - (1s,3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
29% identity, 74% coverage of query (126 bits)
7lomC Ornithine aminotransferase (oat) soaked with its inactivator - (1s, 3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
29% identity, 74% coverage of query (126 bits)
7lomA Ornithine aminotransferase (oat) soaked with its inactivator - (1s, 3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
29% identity, 74% coverage of query (126 bits)
6io1B / B9L0K9 Crystal structure of a novel thermostable (s)-enantioselective omega- transaminase from thermomicrobium roseum (see paper)
31% identity, 72% coverage of query (126 bits)
OAT / P04181 Ornithine aminotransferase (EC 2.6.1.13) from Homo sapiens (see 3 papers)
OAT_HUMAN / P04181 Ornithine aminotransferase, mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Homo sapiens (Human) (see 8 papers)
29% identity, 74% coverage of query (125 bits)
8ez1B Human ornithine aminotransferase (hoat) co-crystallized with its inactivator 3-amino-4-fluorocyclopentenecarboxylic acid
29% identity, 74% coverage of query (125 bits)
8ez1A Human ornithine aminotransferase (hoat) co-crystallized with its inactivator 3-amino-4-fluorocyclopentenecarboxylic acid
29% identity, 74% coverage of query (125 bits)
7tfpC Human ornithine aminotransferase cocrystallized with its inhibitor, (1s,3s)-3-amino-4-(difluoromethylene)cyclopentane-1-carboxylic acid.
29% identity, 74% coverage of query (125 bits)
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Lawrence Berkeley National Laboratory