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Searching for up to 100 curated homologs for WP_012674812.1 NCBI__GCF_000021545.1:WP_012674812.1 (188 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ilvN / O08354 acetohydroxy-acid synthase small subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
    50% identity, 82% coverage of query (165 bits)

ILVH2_ARATH / Q9FFF4 Acetolactate synthase small subunit 2, chloroplastic; ALS-interacting protein 3; Acetohydroxy-acid synthase small subunit 2; Protein valine-tolerant 1 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    46% identity, 94% coverage of query (151 bits)

ILVH1_ARATH / Q93YZ7 Acetolactate synthase small subunit 1, chloroplastic; ALS-interacting protein 1; Acetohydroxyacid synthase small subunit 1 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
    47% identity, 87% coverage of query (142 bits)

Q8RL87 acetolactate synthase (subunit 1/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvN / AAL99357.1 acetohydroxy acid synthase small subunit from Geobacillus stearothermophilus (see paper)
    51% identity, 82% coverage of query (141 bits)

A0QUX7 Acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS; EC 2.2.1.6 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    45% identity, 82% coverage of query (139 bits)

6vz8F / Q93YZ7 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
    48% identity, 85% coverage of query (138 bits)

2pc6A / Q82UZ2 Crystal structure of putative acetolactate synthase- small subunit from nitrosomonas europaea (see paper)
    41% identity, 83% coverage of query (138 bits)

ILVH_MYCTU / P9WKJ3 Putative acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WKJ3 acetolactate synthase (subunit 1/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
    44% identity, 82% coverage of query (137 bits)

ilvH / Q0KCU3 acetohydroxyacid synthase subunit H (EC 2.2.1.6) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
    45% identity, 80% coverage of query (136 bits)

ILVH_NICPL / Q9SMC2 Acetolactate synthase small subunit 1, chloroplastic; Acetohydroxy-acid synthase small subunit; AHAS; ALS from Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco) (see paper)
    47% identity, 83% coverage of query (135 bits)

BrnP / b0078 acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
ilvH / P00894 acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit (EC 2.2.1.6) from Escherichia coli (strain K12) (see 10 papers)
P00894 acetolactate synthase (subunit 1/2) (EC 2.2.1.6) from Escherichia coli (see paper)
ilvH / GB|BAB96647.2 acetolactate synthase, small subunit; EC 2.2.1.6 from Escherichia coli (see paper)
    43% identity, 83% coverage of query (134 bits)

6vz8G / Q93YZ7 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
    45% identity, 84% coverage of query (134 bits)

ilvN / AAB38427.1 acetolactate synthase from Mycobacterium avium (see paper)
    47% identity, 74% coverage of query (131 bits)

ILV6_SCHPO / O60086 Probable acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    32% identity, 87% coverage of query (112 bits)

G4NC97 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Pyricularia oryzae (see paper)
    30% identity, 90% coverage of query (111 bits)

6u9dL / P25605 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
    30% identity, 90% coverage of query (103 bits)

ILV6_YEAST / P25605 Acetolactate synthase small subunit, mitochondrial; Acetohydroxy-acid synthase small subunit; AHAS; ALS from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    30% identity, 90% coverage of query (103 bits)

6wo1B Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit
    32% identity, 83% coverage of query (102 bits)

Build an alignment

Build an alignment for WP_012674812.1 and 18 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Echvi_2057 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) from Echinicola vietnamensis KMM 6221, DSM 17526
    29% identity, 86% coverage of query (77.4 bits)

CA265_RS15810 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) from Pedobacter sp. GW460-11-11-14-LB5
    30% identity, 84% coverage of query (75.5 bits)

BT2076 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) from Bacteroides thetaiotaomicron VPI-5482
    25% identity, 81% coverage of query (54.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory