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Searching for up to 100 curated homologs for WP_012755323.1 NCBI__GCF_000023185.1:WP_012755323.1 (183 a.a.)

Found high-coverage hits (≥70%) to 39 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GB|CAA68625.1 nodulation protein L from Rhizobium leguminosarum bv. viciae (see paper)
    85% identity, 99% coverage of query (320 bits)

RF|NP_435661.1 nodulation protein L from Sinorhizobium meliloti (see paper)
    81% identity, 99% coverage of query (307 bits)

3igjC / A0A6L7H2S4 Crystal structure of maltose o-acetyltransferase complexed with acetyl coenzyme a from bacillus anthracis
    49% identity, 98% coverage of query (179 bits)

Maa / b0459 maltose O-acetyltransferase (EC 2.3.1.79) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
maa / P77791 maltose O-acetyltransferase (EC 2.3.1.79) from Escherichia coli (strain K12) (see 6 papers)
MAA_ECOLI / P77791 Maltose O-acetyltransferase; MAT; Maltose transacetylase; EC 2.3.1.79 from Escherichia coli (strain K12) (see 2 papers)
maa maltose O-acetyltransferase; EC 2.3.1.79 from Escherichia coli K12 (see 5 papers)
maa / CAA11147.1 Maltose Transacetylase from Escherichia coli (see paper)
    49% identity, 97% coverage of query (179 bits)

4isxA / Q18A66 The crystal structure of maltose o-acetyltransferase from clostridium difficile 630 in complex with acetyl-coa
    46% identity, 97% coverage of query (170 bits)

3nz2J / Q9KLB0 Crystal structure of hexapeptide-repeat containing-acetyltransferase vca0836 complexed with acetyl co enzyme a from vibrio cholerae o1 biovar eltor
    41% identity, 100% coverage of query (137 bits)

3nz2C Crystal structure of hexapeptide-repeat containing-acetyltransferase vca0836 complexed with acetyl co enzyme a from vibrio cholerae o1 biovar eltor
    41% identity, 98% coverage of query (135 bits)

Q5HCZ5 galactoside O-acetyltransferase (EC 2.3.1.18) from Staphylococcus aureus (see paper)
    41% identity, 98% coverage of query (130 bits)

5u2kA / Q5HCZ5 Crystal structure of galactoside o-acetyltransferase complex with coa (h3 space group)
    41% identity, 98% coverage of query (130 bits)

3ectA Crystal structure of the hexapeptide-repeat containing- acetyltransferase vca0836 from vibrio cholerae
    42% identity, 97% coverage of query (128 bits)

LacA / b0342 galactoside O-acetyltransferase (EC 2.3.1.18) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lacA / P07464 galactoside O-acetyltransferase (EC 2.3.1.18) from Escherichia coli (strain K12) (see 19 papers)
THGA_ECOLI / P07464 Galactoside O-acetyltransferase; GAT; Acetyl-CoA:galactoside 6-O-acetyltransferase; Thiogalactoside acetyltransferase; Thiogalactoside transacetylase; EC 2.3.1.18 from Escherichia coli (strain K12) (see 5 papers)
P07464 galactoside O-acetyltransferase (EC 2.3.1.18) from Escherichia coli (see paper)
    38% identity, 100% coverage of query (126 bits)

1kruA / P07464 Galactoside acetyltransferase in complex with iptg and coenzyme a (see paper)
    39% identity, 97% coverage of query (125 bits)

1krvA Galactoside acetyltransferase in complex with coa and pnp-beta-gal
    39% identity, 97% coverage of query (125 bits)

1krrA Galactoside acetyltransferase in complex with acetyl-coenzyme a
    39% identity, 97% coverage of query (125 bits)

SAT_STABO / G0YF19 Sophorolipid acetyltransferase; Carboxyhydrate transacetylase; EC 2.3.1.- from Starmerella bombicola (Yeast) (Candida bombicola) (see 4 papers)
    35% identity, 97% coverage of query (124 bits)

WcaF / b2054 colanic acid biosynthesis acetyltransferase WcaF from Escherichia coli K-12 substr. MG1655 (see 7 papers)
wcaF / P0ACD2 colanic acid biosynthesis acetyltransferase WcaF from Escherichia coli (strain K12) (see 6 papers)
    34% identity, 75% coverage of query (84.0 bits)

Q6F4D7 serine O-acetyltransferase (EC 2.3.1.30) from Thermus thermophilus HB8 (see paper)
    33% identity, 75% coverage of query (59.7 bits)

8vr6A Crystal structure of the pcryo_0619 n-acetryltransferase from psychrobacter cryohalolentis k5 in the presence of coa-disulfide
    32% identity, 84% coverage of query (58.2 bits)

8vr7B Crystal structure of the pcryo_0619 n-acetyltransferase from psychrobacter cryohalolentis k5 int he presence of acetyl coenzyme a
    32% identity, 84% coverage of query (58.2 bits)

8vr7E / Q1QD51 Crystal structure of the pcryo_0619 n-acetyltransferase from psychrobacter cryohalolentis k5 int he presence of acetyl coenzyme a
    32% identity, 84% coverage of query (57.8 bits)

Q6IWF9 serine O-acetyltransferase (EC 2.3.1.30) from Noccaea goesingensis (see paper)
    31% identity, 96% coverage of query (55.5 bits)

D9E73_16825 / A0A0A8J6R7 dTDP-viosamine (S)-3-hydroxybutanoyltransferase from Escherichia coli (see paper)
    31% identity, 73% coverage of query (52.8 bits)

Build an alignment

Build an alignment for WP_012755323.1 and 22 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

WbbJ / b2033 putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ from Escherichia coli K-12 substr. MG1655 (see paper)
    29% identity, 79% coverage of query (52.8 bits)

7s3uA Crystal structure of an n-acetyltransferase from helicobacter pullorum in the presence of coenzyme a and dtdp-3-amino-3,6-dideoxy-d-glucose (see paper)
    32% identity, 70% coverage of query (52.0 bits)

7s42A Crystal structure of an n-acetyltransferase from helicobacter pullorum in the presence of coenzyme a and dtdp-3-acetamido-3,6-dideoxy-d- galactose
    32% identity, 70% coverage of query (52.0 bits)

7s41A Crystal structure of an n-acetyltransferase from helicobacter pullorum in the presence of coenzyme a and dtdp-3-acetamido-3,6-dideoxy-d- glucose
    32% identity, 70% coverage of query (52.0 bits)

7s3wA Crystal structure of an n-acetyltransferase from helicobacter pullorum in the presence of coenzyme a and dtdp-3-amino-3,6-dideoxy-d- galactose
    32% identity, 70% coverage of query (52.0 bits)

7s45A Crystal structure of an n-acetyltransferase, c80t mutant, from helicobacter pullorum in the presence of acetyl coenzyme a and dtdp
    30% identity, 70% coverage of query (50.1 bits)

GLMU_STRPN / Q97R46 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) (see 2 papers)
    27% identity, 86% coverage of query (48.5 bits)

1g97A S.Pneumoniae glmu complexed with udp-n-acetylglucosamine and mg2+
    27% identity, 86% coverage of query (48.1 bits)

wbpD / G3XD01 UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase monomer (EC 2.3.1.201) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 4 papers)
WBPD_PSEAE / G3XD01 UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronate N-acetyltransferase; UDP-D-GlcNAc3NA N-acetyltransferase; UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronic acid 3-N-acetyltransferase; EC 2.3.1.201 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 4 papers)
G3XD01 UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase (EC 2.3.1.201) from Pseudomonas aeruginosa (see paper)
    26% identity, 77% coverage of query (47.8 bits)

1hm9A Crystal structure of s.Pneumoniae n-acetylglucosamine-1-phosphate uridyltransferase, glmu, bound to acetyl coenzyme a and udp-n- acetylglucosamine
    27% identity, 86% coverage of query (47.0 bits)

1hm8A / Q97R46 Crystal structure of s.Pneumoniae n-acetylglucosamine-1-phosphate uridyltransferase, glmu, bound to acetyl coenzyme a (see paper)
    27% identity, 86% coverage of query (47.0 bits)

7kr9A Bifunctional enzyme glmu bound to zn(ii)
    27% identity, 86% coverage of query (47.0 bits)

4ac3A S.Pneumoniae glmu in complex with an antibacterial inhibitor
    27% identity, 86% coverage of query (47.0 bits)

4aawA S.Pneumoniae glmu in complex with an antibacterial inhibitor
    27% identity, 86% coverage of query (47.0 bits)

3gvdI / A0A2U2H3H7 Crystal structure of serine acetyltransferase cyse from yersinia pestis
    26% identity, 99% coverage of query (45.4 bits)

3mqhA Crystal structure of the 3-n-acetyl transferase wlbb from bordetella petrii in complex with coa and udp-3-amino-2-acetamido-2,3-dideoxy glucuronic acid
    25% identity, 77% coverage of query (42.4 bits)

3mqgC / A9IH93 Crystal structure of the 3-n-acetyl transferase wlbb from bordetella petrii in complex with acetyl-coa (see paper)
    25% identity, 77% coverage of query (42.4 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory