Searching for up to 100 curated homologs for WP_012759162.1 NCBI__GCF_000023185.1:WP_012759162.1 (293 a.a.)
Found high-coverage hits (≥70%) to 35 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
SYE_THEVB / Q8DLI5 Glutamate--tRNA ligase; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1) (see paper)
33% identity, 92% coverage of query (127 bits)
2cfoA / Q8DLI5 Non-discriminating glutamyl-tRNA synthetase from thermosynechococcus elongatus in complex with glu (see paper)
33% identity, 92% coverage of query (127 bits)
SYEM_HUMAN / Q5JPH6 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial; Glutamate--tRNA(Gln) ligase EARS2, mitochondrial; Glutamyl-tRNA synthetase; GluRS; Mitochondrial glutamyl-tRNA synthetase; mtGluRS; EC 6.1.1.24; EC 6.1.1.17 from Homo sapiens (Human) (see 4 papers)
34% identity, 92% coverage of query (124 bits)
SYEM_ARATH / Q9FEA2 Glutamate--tRNA ligase, chloroplastic/mitochondrial; AtERS; Glutamyl-tRNA synthetase; GluRS; Protein OVULE ABORTION 3; EC 6.1.1.17 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
32% identity, 92% coverage of query (122 bits)
SYE_THET8 / P27000 Glutamate--tRNA ligase; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 2 papers)
2cuzA / P27000 Glutamyl-tRNA synthetase from thermus thermophilus in complex with l- glutamate (see paper)
32% identity, 97% coverage of query (121 bits)
1g59A Glutamyl-tRNA synthetase complexed with tRNA(glu).
32% identity, 97% coverage of query (121 bits)
2cv2A Glutamyl-tRNA synthetase from thermus thermophilus in complex with tRNA(glu) and an enzyme inhibitor, glu-ams
32% identity, 97% coverage of query (121 bits)
2cv1A Glutamyl-tRNA synthetase from thermus thermophilus in complex with tRNA(glu), atp, and an analog of l-glutamate: a quaternary complex
32% identity, 97% coverage of query (121 bits)
1n78A Crystal structure of thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(glu) and glutamol-amp.
32% identity, 97% coverage of query (121 bits)
1j09A Crystal structure of thermus thermophilus glutamyl-tRNA synthetase complexed with atp and glu
32% identity, 97% coverage of query (121 bits)
gltX / P22250 glutamyl-tRNAGlx synthetase (EC 6.1.1.17; EC 6.1.1.24) from Bacillus subtilis (strain 168) (see 4 papers)
30% identity, 87% coverage of query (120 bits)
SYEM_YEAST / P48525 Glutamate--tRNA ligase, mitochondrial; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
31% identity, 92% coverage of query (116 bits)
GltM / b2400 glutamate—tRNA ligase (EC 6.1.1.17) from Escherichia coli K-12 substr. MG1655 (see 39 papers)
gltX / P04805 glutamate—tRNA ligase (EC 6.1.1.17) from Escherichia coli (strain K12) (see 39 papers)
SYE_ECOLI / P04805 Glutamate--tRNA ligase; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Escherichia coli (strain K12) (see 9 papers)
gltX / GB|AAC75457.1 glutamyl-tRNA synthetase; EC 6.1.1.17 from Escherichia coli K12 (see 10 papers)
32% identity, 92% coverage of query (114 bits)
8i9iA / P04805 Glutamyl-tRNA synthetase from escherichia coli bound to glutamate and zinc
32% identity, 92% coverage of query (113 bits)
CCNA_01982 glutamyl-tRNA(Glx) synthetase (EC 6.1.1.24) from Caulobacter crescentus NA1000
32% identity, 91% coverage of query (110 bits)
4griB / O51345 Crystal structure of a glutamyl-tRNA synthetase glurs from borrelia burgdorferi bound to glutamic acid and zinc (see paper)
31% identity, 96% coverage of query (109 bits)
4a91A / P27305 Crystal structure of the glutamyl-queuosine trnaasp synthetase from e. Coli complexed with l-glutamate (see paper)
35% identity, 88% coverage of query (108 bits)
gluQ / PDB|1NZJ glutamyl-Q tRNA(Asp) synthetase; EC 6.1.1.- from Escherichia coli K12 (see 9 papers)
35% identity, 88% coverage of query (108 bits)
GluQ / b0144 glutamyl-Q tRNAAsp synthetase from Escherichia coli K-12 substr. MG1655 (see 10 papers)
gluQ / P27305 glutamyl-Q tRNAAsp synthetase from Escherichia coli (strain K12) (see 9 papers)
GLUQ_ECOLI / P27305 Glutamyl-Q tRNA(Asp) synthetase; Glu-Q-RSs; EC 6.1.1.- from Escherichia coli (strain K12) (see 3 papers)
35% identity, 88% coverage of query (108 bits)
6brlA / A0A1T3HI54 Crystal structure of a glutamate tRNA ligase from elizabethkingia meningosepticum ccug26117 in complex with its amino acid (see paper)
31% identity, 91% coverage of query (104 bits)
Build an alignment for WP_012759162.1 and 20 homologs with ≥ 30% identity
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Q9X2I8 glutamate-tRNAGln ligase (EC 6.1.1.24) from Thermotoga maritima (see paper)
29% identity, 92% coverage of query (103 bits)
3al0C / Q9WY94,Q9X2I8 Crystal structure of the glutamine transamidosome from thermotoga maritima in the glutamylation state. (see paper)
29% identity, 92% coverage of query (103 bits)
Q8IDD3 glutamate-tRNAGln ligase (EC 6.1.1.24) from Plasmodium falciparum (see paper)
27% identity, 92% coverage of query (101 bits)
4g6zA / Q2SX36 Crystal structure of a glutamyl-tRNA synthetase glurs from burkholderia thailandensis bound to l-glutamate (see paper)
31% identity, 92% coverage of query (100 bits)
Q9XCL6 glutamate-tRNA ligase (EC 6.1.1.17) from Pseudomonas aeruginosa (see paper)
31% identity, 90% coverage of query (97.8 bits)
8vc5A / Q9XCL6 Crystal structure of glutamyl-tRNA synthetase glurs from pseudomonas aeruginosa (zinc bound)
31% identity, 90% coverage of query (97.8 bits)
SYEM_SCHPO / Q9HDX9 Glutamate--tRNA ligase, mitochondrial; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
28% identity, 96% coverage of query (97.8 bits)
O26157 glutamate-tRNA ligase (EC 6.1.1.17) from Methanobacterium thermoautotrophicus (see paper)
gltX / GI|2621087 glutamate--tRNA ligase, non-discriminating; EC 6.1.1.17 from Methanothermobacter thermautotrophicus str. Delta H (see paper)
31% identity, 96% coverage of query (88.2 bits)
P9WFV9 glutamate-tRNA ligase (EC 6.1.1.17) from Mycobacterium tuberculosis (see paper)
31% identity, 96% coverage of query (85.5 bits)
A7AS98 glutamate-tRNA ligase (EC 6.1.1.17) from Babesia bovis (see paper)
27% identity, 93% coverage of query (83.6 bits)
SYE2_HELPY / O25360 GlutamylGlutaminyl-tRNA synthetase; GluGlnRS; Glutamate--tRNA ligase 2; GluRS 2; Glutamyl-tRNA synthetase 2; EC 6.1.1.- from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see 2 papers)
25% identity, 93% coverage of query (81.6 bits)
2re8A Glutaminyl-tRNA synthetase mutant c229r with bound analog 5'-o-[n-(l- glutamyl)-sulfamoyl]adenosine
25% identity, 75% coverage of query (72.4 bits)
SYEC_SCHPO / O13775 Probable glutamate--tRNA ligase, cytoplasmic; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
24% identity, 75% coverage of query (61.6 bits)
glnS / P56926 glutaminyl-tRNA synthetase (EC 6.1.1.18) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
24% identity, 82% coverage of query (59.3 bits)
SYQ_YEAST / P13188 Glutamine--tRNA ligase; Glutaminyl-tRNA synthetase; GlnRS; EC 6.1.1.18 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P13188 glutamine-tRNA ligase (EC 6.1.1.18); glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Saccharomyces cerevisiae (see 2 papers)
24% identity, 75% coverage of query (56.6 bits)
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Lawrence Berkeley National Laboratory