Searching for up to 100 curated homologs for WP_012759307.1 NCBI__GCF_000023185.1:WP_012759307.1 (396 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PGA1_c29420 aromatic-amino-acid transaminase [EC:2.6.1.57] from Phaeobacter inhibens BS107
47% identity, 98% coverage of query (382 bits)
HP15_858 phenylalanine aminotransferase (EC 2.6.1.57) from Marinobacter adhaerens HP15
47% identity, 100% coverage of query (364 bits)
TYRB_PARDE / P95468 Aromatic-amino-acid aminotransferase; ARAT; AROAT; EC 2.6.1.57 from Paracoccus denitrificans (see paper)
P95468 aromatic-amino-acid transaminase (EC 2.6.1.57) from Paracoccus denitrificans (see 4 papers)
1ay4A / P95468 Aromatic amino acid aminotransferase without substrate (see paper)
47% identity, 99% coverage of query (362 bits)
2ay9A Aromatic amino acid aminotransferase with 5-phenylvaleric acid
47% identity, 99% coverage of query (362 bits)
2ay8A Aromatic amino acid aminotransferase with 4-(2-thienyl)butyric acid
47% identity, 99% coverage of query (362 bits)
2ay7A Aromatic amino acid aminotransferase with 4-phenylbutyric acid
47% identity, 99% coverage of query (362 bits)
2ay6A Aromatic amino acid aminotransferase with 3-indolebutyric acid
47% identity, 99% coverage of query (362 bits)
2ay5A Aromatic amino acid aminotransferase with 3-indolepropionic acid
47% identity, 99% coverage of query (362 bits)
2ay3A Aromatic amino acid aminotransferase with 3-(3,4-dimethoxyphenyl) propionic acid
47% identity, 99% coverage of query (362 bits)
2ay1A Aromatic amino acid aminotransferase with 4-aminohydrocinnamic acid
47% identity, 99% coverage of query (362 bits)
2ay4B Aromatic amino acid aminotransferase with 3-(p-tolyl)propionic acid
46% identity, 99% coverage of query (350 bits)
2ay2B Aromatic amino acid aminotransferase with cyclohexane propionic acid
46% identity, 99% coverage of query (350 bits)
1ay8B Aromatic amino acid aminotransferase complex with 3-phenylpropionate
46% identity, 99% coverage of query (350 bits)
aspC / Q3IED5 aspartate aminotransferase (EC 2.6.1.1) from Pseudoalteromonas translucida (strain TAC 125) (see paper)
maspC / CAA04961.1 aspartate aminotransferase from Moraxella sp (see paper)
44% identity, 98% coverage of query (348 bits)
AO353_18575 tyrosine aminotransferase (EC 2.6.1.57) from Pseudomonas fluorescens FW300-N2E3
45% identity, 98% coverage of query (344 bits)
AO356_03985 L-phenylalanine transaminase (EC 2.6.1.57) from Pseudomonas fluorescens FW300-N2C3
45% identity, 98% coverage of query (344 bits)
Pf6N2E2_2632 tyrosine aminotransferase (EC 2.6.1.57) from Pseudomonas fluorescens FW300-N2E2
45% identity, 98% coverage of query (344 bits)
tatA / AAA26362.1 tyrosine aminotransferase from Sinorhizobium meliloti (see paper)
47% identity, 96% coverage of query (343 bits)
AspC / b0928 aspartate aminotransferase (EC 2.6.1.1; EC 2.6.1.57; EC 2.6.1.27; EC 2.6.1.5; EC 2.6.1.7; EC 2.6.1.3) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
aspC / P00509 aspartate aminotransferase (EC 2.6.1.1; EC 2.6.1.7; EC 2.6.1.3) from Escherichia coli (strain K12) (see 71 papers)
AAT_ECOLI / P00509 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Escherichia coli (strain K12) (see 4 papers)
A0A140ND68 aspartate transaminase (EC 2.6.1.1) from Escherichia coli (see paper)
D3H0F7 aspartate transaminase (EC 2.6.1.1) from Escherichia coli (see paper)
P00509 aspartate transaminase (EC 2.6.1.1) from Escherichia coli (see 10 papers)
43% identity, 99% coverage of query (341 bits)
5vwrA E.Coli aspartate aminotransferase-(1r,3s,4s)-3-amino-4- fluorocyclopentane-1-carboxylic acid (fcp)-alpha-ketoglutarate
43% identity, 99% coverage of query (341 bits)
5t4lA Plp and gaba trigger gabr-mediated transcription regulation in bacillus subsidies via external aldimine formation
43% identity, 99% coverage of query (341 bits)
3qpgA Crystal structures of escherichia coli aspartate aminotransferase reconstituted with 1-deaza-pyridoxal 5'-phosphate: internal aldimine and stable l-aspartate external aldimine
43% identity, 99% coverage of query (341 bits)
3pa9A Mechanism of inactivation of e. Coli aspartate aminotransferase by (s)-4-amino-4,5-dihydro-2-furancarboxylic acid (s-adfa) ph 7.5
43% identity, 99% coverage of query (341 bits)
1x2aA Crystal structure of e.Coli aspat complexed with n-phosphopyridoxyl-d- glutamic acid
43% identity, 99% coverage of query (341 bits)
1x29A Crystal structure of e.Coli aspat complexed with n-phosphopyridoxyl-2- methyl-l-glutamic acid
43% identity, 99% coverage of query (341 bits)
1x28A Crystal structure of e.Coli aspat complexed with n-phosphopyridoxyl-l- glutamic acid
43% identity, 99% coverage of query (341 bits)
1cq8A Aspartate aminotransferase (E.C. 2.6.1.1) complexed with c6-pyridoxal- 5p-phosphate
43% identity, 99% coverage of query (341 bits)
1cq7A Aspartate aminotransferase (E.C. 2.6.1.1) complexed with c5-pyridoxal- 5p-phosphate
43% identity, 99% coverage of query (341 bits)
1cq6A Aspartate aminotransferase complex with c4-pyridoxal-5p-phosphate
43% identity, 99% coverage of query (341 bits)
1c9cA Aspartate aminotransferase complexed with c3-pyridoxal-5'-phosphate
43% identity, 99% coverage of query (341 bits)
1aslA Crystal structures of escherichia coli aspartate aminotransferase in two conformations: comparison of an unliganded open and two liganded closed forms
43% identity, 99% coverage of query (341 bits)
1aseA The structure of wild type e. Coli aspartate aminotransferase reconstituted with plp-n-oxide
43% identity, 99% coverage of query (341 bits)
1asdA The structure of wild type e. Coli aspartate aminotransferase reconstituted with n-meplp
43% identity, 99% coverage of query (341 bits)
1artA X-ray crystallographic study of pyridoxal 5'-phosphate-type aspartate aminotransferases from escherichia coli in open and closed form
43% identity, 99% coverage of query (341 bits)
1argA Aspartate aminotransferase, phospho-5'-pyridoxyl aspartate complex
43% identity, 99% coverage of query (341 bits)
1amsA X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from escherichia coli in three forms
43% identity, 99% coverage of query (341 bits)
1aibA Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking the pyridoxal-5'-phosphate binding lysine residue
43% identity, 99% coverage of query (339 bits)
1aiaA Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking the pyridoxal-5'-phosphate binding lysine residue
43% identity, 99% coverage of query (339 bits)
PfGW456L13_4396 tyrosine aminotransferase (EC 2.6.1.57) from Pseudomonas fluorescens GW456-L13
44% identity, 99% coverage of query (338 bits)
1ascA The structural basis for the reduced activity of the d223a(d222a) active site mutant of e. Coli aspartate aminotransferase
43% identity, 99% coverage of query (338 bits)
1ahxA Aspartate aminotransferase hexamutant
42% identity, 99% coverage of query (337 bits)
1ahgA Aspartate aminotransferase hexamutant
42% identity, 99% coverage of query (337 bits)
1ahfA Aspartate aminotransferase hexamutant
42% identity, 99% coverage of query (337 bits)
phhC / P43336 tyrosine aminotransferase subunit (EC 2.6.1.1) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
44% identity, 97% coverage of query (335 bits)
8e9cB / P00509 Crystal structure of e. Coli aspartate aminotransferase mutant aifs in the ligand-free form at 100 k (see paper)
42% identity, 99% coverage of query (333 bits)
1yooA Aspartate aminotransferase mutant atb17 with isovaleric acid
42% identity, 99% coverage of query (329 bits)
Psest_0779 tyrosine aminotransferase (EC 2.6.1.57) from Pseudomonas stutzeri RCH2
43% identity, 99% coverage of query (326 bits)
2q7wA Structural studies reveals the inactivation of e. Coli l-aspartate aminotransferase (s)-4,5-amino-dihydro-2-thiophenecarboxylic acid (sadta) via two mechanisms at ph 6.0
43% identity, 92% coverage of query (318 bits)
tyrB / O85746 tyrosine aminotransferase monomer (EC 2.6.1.88) from Klebsiella pneumoniae (see paper)
TYRB_KLEPN / O85746 Tyrosine aminotransferase; TyrAT; Aromatic-amino-acid transaminase; Aspartate aminotransferase; EC 2.6.1.5; EC 2.6.1.57; EC 2.6.1.1 from Klebsiella pneumoniae (see paper)
41% identity, 99% coverage of query (298 bits)
4rkcA / C7E5X4 Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 (see paper)
38% identity, 99% coverage of query (290 bits)
6zvgA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-indole-3-lactic acid
38% identity, 99% coverage of query (290 bits)
6zurA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-p-hydroxyphenyllactic acid
38% identity, 99% coverage of query (290 bits)
6zupA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-(-)-3-phenyllactic acid
38% identity, 99% coverage of query (290 bits)
4rkdC Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with aspartic acid
38% identity, 99% coverage of query (290 bits)
4rkdA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with aspartic acid
38% identity, 99% coverage of query (290 bits)
3fslA / P04693 Crystal structure of tyrosine aminotransferase tripple mutant (p181q, r183g,a321k) from escherichia coli at 2.35 a resolution
40% identity, 99% coverage of query (287 bits)
TyrB / b4054 tyrosine aminotransferase (EC 2.6.1.57; EC 2.6.1.6; EC 2.6.1.42; EC 2.6.1.1; EC 2.6.1.5; EC 2.6.1.27) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
tyrB / P04693 tyrosine aminotransferase (EC 2.6.1.57; EC 2.6.1.6; EC 2.6.1.1) from Escherichia coli (strain K12) (see 3 papers)
TYRB_ECOLI / P04693 Aromatic-amino-acid aminotransferase; ARAT; AROAT; Beta-methylphenylalanine transaminase; EC 2.6.1.57; EC 2.6.1.107 from Escherichia coli (strain K12) (see paper)
P04693 aromatic-amino-acid transaminase (EC 2.6.1.57) from Escherichia coli (see paper)
tyrB / GB|AAC77024.1 aromatic-amino-acid transaminase TyrB; EC 2.6.1.57 from Escherichia coli K12 (see 5 papers)
40% identity, 99% coverage of query (283 bits)
3tatA Tyrosine aminotransferase from e. Coli
40% identity, 99% coverage of query (283 bits)
RR42_RS33490 Aromatic-amino-acid aminotransferase (EC 2.6.1.57) from Cupriavidus basilensis FW507-4G11
39% identity, 99% coverage of query (277 bits)
PP_3590 aromatic-amino-acid transaminase (EC 2.6.1.57) from Pseudomonas putida KT2440
38% identity, 99% coverage of query (275 bits)
pat / Q5P8C9 aromatic-amino-acid aminotransferase (EC 2.6.1.1) from Aromatoleum aromaticum (strain EbN1) (see paper)
39% identity, 99% coverage of query (274 bits)
W0PFQ7 aspartate transaminase (EC 2.6.1.1) from Advenella mimigardefordensis (see paper)
38% identity, 99% coverage of query (273 bits)
AAT5_ARATH / P46248 Aspartate aminotransferase, chloroplastic; Transaminase A; EC 2.6.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
36% identity, 98% coverage of query (264 bits)
AAT2 / P23542 aspartate aminotransferase (EC 2.6.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
AATC_YEAST / P23542 Aspartate aminotransferase, cytoplasmic; Transaminase A; EC 2.6.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
34% identity, 98% coverage of query (253 bits)
1yaaA / P23542 Aspartate aminotransferase from saccharomyces cerevisiae cytoplasm (see paper)
34% identity, 98% coverage of query (253 bits)
AAT1 potential aspartate aminotransferase from Candida albicans (see paper)
33% identity, 99% coverage of query (251 bits)
AAT3_ARATH / P46644 Aspartate aminotransferase 3, chloroplastic; Protein YELLOW-LEAF-SPECIFIC GENE 4; Transaminase A; EC 2.6.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
35% identity, 100% coverage of query (249 bits)
AAT1_ARATH / P46643 Aspartate aminotransferase, mitochondrial; Transaminase A; EC 2.6.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
35% identity, 97% coverage of query (246 bits)
AATM_CHICK / P00508 Aspartate aminotransferase, mitochondrial; mAspAT; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Gallus gallus (Chicken) (see 4 papers)
34% identity, 97% coverage of query (246 bits)
AATM_SCHPO / O94320 Aspartate aminotransferase, mitochondrial; Transaminase A; EC 2.6.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
33% identity, 99% coverage of query (245 bits)
7aatA / P00508 X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase (see paper)
34% identity, 97% coverage of query (244 bits)
9aatA X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase
34% identity, 97% coverage of query (244 bits)
1oxoA Aspartate aminotransferase, h-asp complex, open conformation
34% identity, 97% coverage of query (244 bits)
1maqA Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase
34% identity, 97% coverage of query (244 bits)
1mapA Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase
34% identity, 97% coverage of query (244 bits)
1ivrA Structure of aspartate aminotransferase
34% identity, 97% coverage of query (244 bits)
1amaA Domain closure in mitochondrial aspartate aminotransferase
34% identity, 97% coverage of query (244 bits)
Q4D080 aspartate transaminase (EC 2.6.1.1) from Trypanosoma cruzi (see paper)
cASAT aminotransferase; EC 2.6.1.- from Trypanosoma cruzi strain CL Brener (see paper)
35% identity, 98% coverage of query (243 bits)
1akcA Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking its pyridoxal-5'-phosphate-binding lysine residue
34% identity, 97% coverage of query (242 bits)
1akbA Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking its pyridoxal-5'-phosphate-binding lysine residue
34% identity, 97% coverage of query (242 bits)
1akaB Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking its pyridoxal-5'-phosphate-binding lysine residue
34% identity, 97% coverage of query (242 bits)
AATM_MOUSE / P05202 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Mus musculus (Mouse) (see 4 papers)
P05202 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Mus musculus (see 3 papers)
34% identity, 97% coverage of query (239 bits)
AATM_DANRE / Q7SYK7 Aspartate aminotransferase, mitochondrial; mAspAT; Glutamate oxaloacetate transaminase 2a; Glutamic-oxaloacetic transaminase 2a, mitochondrial; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
32% identity, 99% coverage of query (239 bits)
AAT2_ARATH / P46645 Aspartate aminotransferase, cytoplasmic isozyme 1; Transaminase A; EC 2.6.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
34% identity, 99% coverage of query (239 bits)
Got2 / P00507 mitochondrial aspartate aminotransferase subunit (EC 2.6.1.1) from Rattus norvegicus (see 5 papers)
AATM_RAT / P00507 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Rattus norvegicus (Rat) (see 2 papers)
P00507 aspartate transaminase (EC 2.6.1.1) from Rattus norvegicus (see 2 papers)
34% identity, 97% coverage of query (239 bits)
3pd6A Crystal structure of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-iv
34% identity, 97% coverage of query (239 bits)
Q964F1 aspartate transaminase (EC 2.6.1.1) from Trypanosoma brucei (see paper)
cASAT aminotransferase; EC 2.6.1.- from Trypanosoma brucei TREU927 (see paper)
36% identity, 98% coverage of query (238 bits)
8skrA / P00505 Human liver mitochondrial aspartate aminotransferase (see paper)
34% identity, 97% coverage of query (238 bits)
P12344 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1 from Bos taurus (Bovine)
34% identity, 97% coverage of query (238 bits)
GOT2 / P00505 Aspartate aminotransferase, mitochondrial (EC 2.6.1.23; EC 2.6.1.1; EC 2.6.1.7) from Homo sapiens (see 4 papers)
AATM_HUMAN / P00505 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Homo sapiens (Human) (see 3 papers)
P00505 aspartate transaminase (EC 2.6.1.1) from Homo sapiens (see 2 papers)
TC 9.A.70.1.1 / P00505 Mitochondrial aspartate amino transferase of 430 aas and 1 TMS, AAT or GOT2 from Homo sapiens
34% identity, 97% coverage of query (237 bits)
6ezlA / Q4D080 Crystal structure of aspartate aminotransferase from trypanosoma cruzi at 2.07 angstrom resolution
35% identity, 98% coverage of query (236 bits)
Q385Q9 aspartate transaminase (EC 2.6.1.1) from Trypanosoma brucei brucei (see paper)
mASAT aspartate aminotransferase; EC 2.6.1.1 from Trypanosoma brucei TREU927 (see paper)
34% identity, 97% coverage of query (235 bits)
Q964F0 aspartate transaminase (EC 2.6.1.1) from Trypanosoma brucei (see paper)
34% identity, 97% coverage of query (234 bits)
4w5kA / Q385Q9 Structure of a mitochondrial aspartate aminotransferase from trypanosoma brucei, k237a mutant (see paper)
34% identity, 94% coverage of query (229 bits)
6jpkA / O42652 Crystal structure of s. Pombe aspartate aminotransferase (see paper)
33% identity, 98% coverage of query (228 bits)
AATC_SCHPO / O42652 Aspartate aminotransferase, cytoplasmic; Transaminase A; EC 2.6.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
O42652 aspartate transaminase (EC 2.6.1.1) from Schizosaccharomyces pombe (see paper)
33% identity, 98% coverage of query (228 bits)
AAT3 / Q43305 aspartate transaminase (EC 2.6.1.1) from Panicum miliaceum (see paper)
31% identity, 99% coverage of query (220 bits)
2cstA / P00504 Crystal structure of the closed form of chicken cytosolic aspartate aminotransferase at 1.9 angstroms resolution (see paper)
33% identity, 96% coverage of query (219 bits)
AATC_CHICK / P00504 Aspartate aminotransferase, cytoplasmic; cAspAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A; EC 2.6.1.1; EC 2.6.1.3 from Gallus gallus (Chicken) (see 2 papers)
33% identity, 96% coverage of query (219 bits)
7turB / P00503 Joint x-ray/neutron structure of aspastate aminotransferase (aat) in complex with pyridoxamine 5'-phosphate (pmp) (see paper)
32% identity, 95% coverage of query (216 bits)
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Lawrence Berkeley National Laboratory