Searching for up to 100 curated homologs for WP_012759340.1 NCBI__GCF_000023185.1:WP_012759340.1 (407 a.a.)
Found high-coverage hits (≥70%) to 30 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ASSY_THET8 / P59846 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 2 papers)
63% identity, 97% coverage of query (487 bits)
1j1zA / P59846 Crystal structure of thermus thermophilus hb8 argininosuccinate synthetase in complex with substrate (see paper)
63% identity, 97% coverage of query (478 bits)
1j20A Crystal structure of thermus thermophilus hb8 argininosuccinate synthetase in complex with product
63% identity, 97% coverage of query (478 bits)
1kh3A Crystal structure of thermus thermophilus hb8 argininosuccinate synthetase in complex with inhibitor
62% identity, 97% coverage of query (470 bits)
S4V5K7 argininosuccinate synthase (EC 6.3.4.5) from Protopterus annectens (see paper)
53% identity, 96% coverage of query (411 bits)
ASSY_THEMA / Q9X2A1 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
51% identity, 96% coverage of query (402 bits)
A4I066 argininosuccinate synthase (EC 6.3.4.5) from Leishmania infantum (see paper)
50% identity, 98% coverage of query (382 bits)
ASSY_RAT / P09034 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Rattus norvegicus (Rat) (see paper)
49% identity, 96% coverage of query (380 bits)
H9BG20 argininosuccinate synthase (EC 6.3.4.5) from Leishmania donovani (see 2 papers)
49% identity, 98% coverage of query (380 bits)
ASSY_MOUSE / P16460 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Mus musculus (Mouse) (see 3 papers)
P16460 argininosuccinate synthase (EC 6.3.4.5) from Mus musculus (see 4 papers)
49% identity, 96% coverage of query (380 bits)
ASS1 / P00966 Argininosuccinate synthase (EC 6.3.4.5) from Homo sapiens (see 7 papers)
ASSY_HUMAN / P00966 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Homo sapiens (Human) (see 21 papers)
P00966 argininosuccinate synthase (EC 6.3.4.5) from Homo sapiens (see 9 papers)
49% identity, 96% coverage of query (377 bits)
2nz2A / P00966 Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline (see paper)
49% identity, 96% coverage of query (374 bits)
ASSY_BOVIN / P14568 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Bos taurus (Bovine) (see paper)
48% identity, 96% coverage of query (374 bits)
ASSY_SCHPO / O94354 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
arg12 / RF|NP_595183.1 argininosuccinate synthase (predicted); EC 6.3.4.5 from Schizosaccharomyces pombe (see 2 papers)
47% identity, 97% coverage of query (363 bits)
ASSY_SYNY3 / P77973 Argininosuccinate synthase; Argininosuccinate synthetase; Citrulline--aspartate ligase; SyArgG; EC 6.3.4.5 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
47% identity, 97% coverage of query (355 bits)
ARG1 argininosuccinate synthase; EC 6.3.4.5 from Candida albicans (see paper)
46% identity, 96% coverage of query (351 bits)
Q2Z0F6 argininosuccinate synthase (EC 6.3.4.5) from Agaricus bisporus (see paper)
45% identity, 98% coverage of query (343 bits)
argG / CAB95023.1 argininosuccinate synthetase from Moritella abyssi (see paper)
45% identity, 98% coverage of query (343 bits)
7k5zA / Q5ZY78 Crystal structure of argininosuccinate synthase from legionella pneumophila philadelphia 1 in complex with anppnp and a substrate analogue arginine
45% identity, 98% coverage of query (342 bits)
ASSY_YEAST / P22768 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
44% identity, 96% coverage of query (337 bits)
4xfjB / G7CBN9 Crystal structure of argininosuccinate synthase from mycobacterium thermoresistibile in complex with amppnp and arginine
42% identity, 98% coverage of query (320 bits)
argG / CAA88926.1 argininosuccinate synthetase from Streptomyces clavuligerus (see 3 papers)
43% identity, 98% coverage of query (316 bits)
ABZR86_RS08715 arginosuccinate synthetase (EC 6.3.4.5) from Dyella japonica UNC79MFTsu3.2
34% identity, 98% coverage of query (174 bits)
Build an alignment for WP_012759340.1 and 23 homologs with ≥ 30% identity
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BT3760 arginosuccinate synthetase (EC 6.3.4.5) from Bacteroides thetaiotaomicron VPI-5482
29% identity, 96% coverage of query (168 bits)
5us8A / Q7VTJ9 2.15 angstrom resolution crystal structure of argininosuccinate synthase from bordetella pertussis
31% identity, 92% coverage of query (146 bits)
6e5yA 1.50 angstrom resolution crystal structure of argininosuccinate synthase from bordetella pertussis in complex with amp.
31% identity, 92% coverage of query (146 bits)
argG / BAC65286.1 argininosuccinate synthase from Burkholderia multivorans (see paper)
29% identity, 95% coverage of query (139 bits)
ArgG / b3172 argininosuccinate synthetase (EC 6.3.4.5) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ASSY_ECOLI / P0A6E4 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Escherichia coli (strain K12) (see 2 papers)
argG / RF|NP_417640 argininosuccinate synthase from Escherichia coli K12 (see paper)
28% identity, 95% coverage of query (128 bits)
1k97A Crystal structure of e. Coli argininosuccinate synthetase in complex with aspartate and citrulline
28% identity, 91% coverage of query (125 bits)
1kp3A / P0A6E4 Crystal structure of e. Coli argininosuccinate synthetase in complex with atp and citrulline (see paper)
29% identity, 85% coverage of query (124 bits)
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Lawrence Berkeley National Laboratory