Searching for up to 100 curated homologs for WP_012759558.1 NCBI__GCF_000023185.1:WP_012759558.1 (222 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

trpF / GB|AAA21897.1 phosphoribosylanthranilate isomerase; EC 5.3.1.24 from Acinetobacter calcoaceticus (see paper)
    35% identity, 97% coverage of query (119 bits)

trpF phosphoribosylanthranilate isomerase; EC 5.3.1.24 from Burkholderia multivorans ATCC 17616 (see paper)
trpF / BAC65263.1 N-(5'-phosphoribosyl) anthranilate isomerase from Burkholderia multivorans (see paper)
    36% identity, 96% coverage of query (111 bits)

BT0528 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Bacteroides thetaiotaomicron VPI-5482
    35% identity, 93% coverage of query (111 bits)

trpF / Q56320 phosphoribosylanthranilate isomerase subunit (EC 5.3.1.24) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
1nsjA / Q56320 Crystal structure of phosphoribosyl anthranilate isomerase from thermotoga maritima (see paper)
    34% identity, 91% coverage of query (98.2 bits)

P24920 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Phytophthora parasitica (see paper)
    30% identity, 94% coverage of query (93.2 bits)

1lbmA Crystal structure of phosphoribosyl anthranilate isomerase (prai) in complex with reduced 1-(o-carboxyphenylamino)-1-deoxyribulose 5- phosphate (rcdrp)
    32% identity, 91% coverage of query (84.0 bits)

TRPF_YEAST / P00912 N-(5'-phosphoribosyl)anthranilate isomerase; PRAI; EC 5.3.1.24 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    32% identity, 95% coverage of query (81.3 bits)

PAI2_ARATH / Q42527 N-(5'-phosphoribosyl)anthranilate isomerase 2, chloroplastic; EC 5.3.1.24 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    30% identity, 96% coverage of query (79.3 bits)

PAI1_ARATH / Q42440 N-(5'-phosphoribosyl)anthranilate isomerase 1, chloroplastic; EC 5.3.1.24 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    31% identity, 95% coverage of query (79.0 bits)

Build an alignment

Build an alignment for WP_012759558.1 and 9 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

A0A0H4BJU5 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Saccharomycopsis fibuligera (see paper)
    25% identity, 91% coverage of query (70.9 bits)

TrpC / b1262 fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (EC 4.1.1.48; EC 5.3.1.24) from Escherichia coli K-12 substr. MG1655 (see 17 papers)
trpC / P00909 fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (EC 4.1.1.48; EC 5.3.1.24) from Escherichia coli (strain K12) (see 16 papers)
P00909 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Escherichia coli (see 2 papers)
    29% identity, 93% coverage of query (70.1 bits)

1piiA / P00909 Three-dimensional structure of the bifunctional enzyme phosphoribosylanthranilate isomerase: indoleglycerolphosphate synthase from escherichia coli refined at 2.0 angstroms resolution (see paper)
    29% identity, 93% coverage of query (70.1 bits)

Q8U092 phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Pyrococcus furiosus (see paper)
    29% identity, 91% coverage of query (67.4 bits)

TRP1 / CAA92584.1 N-(5'-phosphoribosyl)anthranilate isomerase from Lipomyces starkeyi (see paper)
    32% identity, 86% coverage of query (66.2 bits)

trpF / B0B7P4 phosphoribosylanthranilate isomerase (EC 5.3.1.24; EC 4.2.1.160) from Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) (see paper)
B0B7P4 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase (EC 4.2.1.160); phosphoribosylanthranilate isomerase (EC 5.3.1.24) from Chlamydia trachomatis (see paper)
    28% identity, 87% coverage of query (62.8 bits)

trpC anthranilate synthase component 2; EC 4.1.3.27 from Emericella nidulans (see 4 papers)
    28% identity, 95% coverage of query (50.1 bits)

7etxA / P06560 Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpc) from corynebacterium glutamicum (see paper)
    29% identity, 88% coverage of query (49.7 bits)

7etyA Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpc) from corynebacterium glutamicum in complex with reduced 1-(o-carboxyphenylamino)-1- deoxyribulose 5-phosphate (rcdrp)
    29% identity, 88% coverage of query (49.7 bits)

TRP1 N-(5'-phosphoribosyl)anthranilate isomerase; EC 5.3.1.24 from Candida albicans (see 3 papers)
    26% identity, 95% coverage of query (49.3 bits)

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