Searching for up to 100 curated homologs for WP_012853365.1 NCBI__GCF_000024385.1:WP_012853365.1 (347 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q9WYH8 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Thermotoga maritima (see paper)
3pg9A / Q9WYH8 Thermotoga maritima dah7p synthase in complex with inhibitor (see paper)
    54% identity, 96% coverage of query (372 bits)

1rzmA Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahps) from thermotoga maritima complexed with cd2+, pep and e4p
    54% identity, 96% coverage of query (372 bits)

4grsA / Q8U0A9,Q9WYH8 Crystal structure of a chimeric dah7ps (see paper)
    53% identity, 93% coverage of query (365 bits)

4c1kA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    56% identity, 72% coverage of query (301 bits)

1zcoB Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    56% identity, 72% coverage of query (299 bits)

1zcoA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    56% identity, 72% coverage of query (299 bits)

5j6fA / L8A208 Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
    54% identity, 74% coverage of query (297 bits)

3nvtA / Q8Y6T2 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
    57% identity, 70% coverage of query (295 bits)

3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate
    57% identity, 70% coverage of query (295 bits)

P39912 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54); chorismate mutase (EC 5.4.99.5) from Bacillus subtilis (see paper)
    54% identity, 76% coverage of query (278 bits)

P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168)
    54% identity, 76% coverage of query (278 bits)

Q9YEJ7 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Aeropyrum pernix (see paper)
    60% identity, 75% coverage of query (255 bits)

1vs1D / Q9YEJ7 Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahp synthase) from aeropyrum pernix in complex with mn2+ and pep
    60% identity, 75% coverage of query (255 bits)

ccmA / BAA05463.1 32.4kD protein from Synechocystis sp. PCC 6803 (see paper)
    45% identity, 84% coverage of query (254 bits)

A0A482F152 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from uncultured bacterium (see paper)
    50% identity, 70% coverage of query (227 bits)

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Build an alignment for WP_012853365.1 and 15 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

P95514 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Mannheimia haemolytica (see paper)
    27% identity, 73% coverage of query (92.4 bits)

P45251 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Haemophilus influenzae (see paper)
    27% identity, 72% coverage of query (91.7 bits)

P0CD74 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Chlamydia trachomatis (see paper)
    27% identity, 73% coverage of query (86.3 bits)

Q9ZFK4 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Pseudomonas aeruginosa (see paper)
    24% identity, 73% coverage of query (81.6 bits)

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