Searching for up to 100 curated homologs for WP_012964674.1 NCBI__GCF_000025505.1:WP_012964674.1 (777 a.a.)
Found high-coverage hits (≥70%) to 8 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
hdrA2 / Q8TM02 HdrA2 (EC 1.8.7.3; EC 1.8.98.4) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see 2 papers)
HDRA2_METAC / Q8TM02 Ferredoxin/F(420)H(2)-dependent CoB-CoM heterodisulfide reductase subunit A; Coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase subunit A; Ferredoxin:CoB-CoM heterodisulfide reductase subunit A; EC 1.8.7.3; EC 1.8.98.4 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see 2 papers)
53% identity, 100% coverage of query (877 bits)
5odcA / A0A2D0TCB9 Heterodisulfide reductase / [nife]-hydrogenase complex from methanothermococcus thermolithotrophicus at 2.3 a resolution (see paper)
52% identity, 82% coverage of query (677 bits)
5odhG Heterodisulfide reductase / [nife]-hydrogenase complex from methanothermococcus thermolithotrophicus soaked with heterodisulfide for 3.5 minutes
52% identity, 82% coverage of query (677 bits)
HDRA_METTM / Q50756 H(2):CoB-CoM heterodisulfide,ferredoxin reductase subunit A; CoB--CoM heterodisulfide reductase iron-sulfur subunit A; EC 1.8.98.5 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see 4 papers)
Q50756 H2:CoB-CoM heterodisulfide,ferredoxin reductase (EC 1.8.98.5) from Methanothermobacter marburgensis (see paper)
hdrA CoB--CoM heterodisulfide reductase iron-sulfur subunit A; EC 1.8.98.1 from Methanothermobacter marburgensis str. Marburg (see 5 papers)
52% identity, 82% coverage of query (675 bits)
HDRA_METMP / Q6LWL2 H(2)/formate:CoB-CoM heterodisulfide,ferredoxin reductase subunit A; CoB--CoM heterodisulfide reductase iron-sulfur subunit A; EC 1.8.98.5; EC 1.8.98.6 from Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL) (see 2 papers)
Q6LWL2 dihydromethanophenazine:CoB-CoM heterodisulfide reductase (EC 1.8.98.1) from Methanococcus maripaludis (see paper)
49% identity, 83% coverage of query (640 bits)
7bkdA / Q2FKZ1 Formate dehydrogenase - heterodisulfide reductase - formylmethanofuran dehydrogenase complex from methanospirillum hungatei (heterodislfide reductase core and mobile arm in conformational state 1, composite structure) (see paper)
48% identity, 82% coverage of query (566 bits)
HDLA_ARCPA / P84626 Heterodisulfide reductase subunit A-like protein; EC 1.8.-.- from Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18) (see paper)
45% identity, 83% coverage of query (546 bits)
hdrA1 / Q8TLB0 HdrA1 (EC 1.8.7.3) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
HDRA1_METAC / Q8TLB0 Ferredoxin:CoB-CoM heterodisulfide reductase subunit A; EC 1.8.7.3 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
37% identity, 90% coverage of query (486 bits)
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Lawrence Berkeley National Laboratory