Searching for up to 100 curated homologs for WP_012964845.1 NCBI__GCF_000025505.1:WP_012964845.1 (358 a.a.)
Found high-coverage hits (≥70%) to 36 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
carA / CAB89872.1 carbamoyl phosphate synthetase small subunit from Lactococcus lactis (see paper)
47% identity, 100% coverage of query (343 bits)
pyrAA / P25993 pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit) (EC 6.3.5.5) from Bacillus subtilis (strain 168) (see 4 papers)
CARA_BACSU / P25993 Carbamoyl phosphate synthase pyrimidine-specific small chain; Carbamoyl phosphate synthetase glutamine chain 2; EC 6.3.5.5 from Bacillus subtilis (strain 168) (see paper)
49% identity, 98% coverage of query (338 bits)
CARA_LACPL / P77885 Carbamoyl phosphate synthase pyrimidine-specific small chain; Carbamoyl phosphate synthetase glutamine chain 2; CPS-P; EC 6.3.5.5 from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) (see paper)
46% identity, 99% coverage of query (317 bits)
pyrAa1 / CAJ75871.1 PyrAa1 protein from Lactobacillus plantarum subsp. plantarum (see paper)
45% identity, 99% coverage of query (317 bits)
CarA / b0032 carbamoyl phosphate synthetase subunit α (EC 6.3.5.5) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
carA / P0A6F1 carbamoyl-phosphate synthetase small subunit (EC 6.3.5.5) from Escherichia coli (strain K12) (see 10 papers)
CARA_ECOLI / P0A6F1 Carbamoyl phosphate synthase small chain; Carbamoyl phosphate synthetase glutamine chain; EC 6.3.5.5 from Escherichia coli (strain K12) (see 4 papers)
47% identity, 99% coverage of query (317 bits)
carA / AAA19046.1 carbamoyl phosphate synthetase light subunit from Pseudomonas aeruginosa (see paper)
46% identity, 99% coverage of query (317 bits)
1ce8B Carbamoyl phosphate synthetase from escherichis coli with complexed with the allosteric ligand imp
47% identity, 99% coverage of query (317 bits)
CARA_ARATH / Q9LVW7 Carbamoyl phosphate synthase small chain, chloroplastic; Carbamoyl phosphate synthetase glutamine chain; Protein VENOSA 6; EC 6.3.5.5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
44% identity, 98% coverage of query (315 bits)
B9V284 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Medicago truncatula (see paper)
43% identity, 98% coverage of query (315 bits)
CAD / P27708 CAD protein (EC 3.5.2.3; EC 6.3.5.5; EC 2.1.3.2) from Homo sapiens (see 6 papers)
PYR1_HUMAN / P27708 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Homo sapiens (Human) (see 11 papers)
P27708 aspartate carbamoyltransferase (EC 2.1.3.2); dihydroorotase (EC 3.5.2.3); carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Homo sapiens (see 7 papers)
43% identity, 99% coverage of query (314 bits)
PYR1_MESAU / P08955 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Mesocricetus auratus (Golden hamster) (see 2 papers)
P08955 dihydroorotase (EC 3.5.2.3) from Mesocricetus auratus (see 2 papers)
44% identity, 99% coverage of query (313 bits)
CARA_NEUCR / P22572 Carbamoyl phosphate synthase arginine-specific small chain; CPS; CPS-arg; CPSase; Arginine-specific carbamoyl phosphate synthetase, glutamine chain; Glutamine-dependent carbamoyl phosphate synthetase; EC 6.3.5.5 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 6 papers)
46% identity, 97% coverage of query (313 bits)
1c3oB / P0A6F1 Crystal structure of the carbamoyl phosphate synthetase: small subunit mutant c269s with bound glutamine (see paper)
46% identity, 99% coverage of query (313 bits)
CARA_SCHPO / O60060 Carbamoyl phosphate synthase arginine-specific small chain; CPS-A; Arginine-specific carbamoyl phosphate synthetase, glutamine chain; EC 6.3.5.5 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
arg5 / GI|3116139 arginine specific carbamoyl-phosphate synthase subunit Arg5 (predicted) from Schizosaccharomyces pombe (see paper)
43% identity, 99% coverage of query (304 bits)
PYR1_SQUAC / Q91437 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Squalus acanthias (Spiny dogfish) (see paper)
43% identity, 98% coverage of query (301 bits)
carA / AAA19049.1 carbamoyl phosphate synthetase light subunit from Pseudomonas stutzeri (see paper)
44% identity, 99% coverage of query (298 bits)
PYR1_CAEEL / Q18990 Multifunctional protein pyr-1; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Caenorhabditis elegans (see 2 papers)
42% identity, 98% coverage of query (298 bits)
Q8RSS4 carbamoyl-phosphate synthase (glutamine-hydrolysing) (subunit 2/2) (EC 6.3.5.5) from Halomonas eurihalina (see paper)
44% identity, 98% coverage of query (295 bits)
URA2 / P07259 carbamoyl phosphate synthase/aspartate carbamoyltransferase (EC 2.1.3.2; EC 6.3.5.5) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 8 papers)
PYR1_YEAST / P07259 Multifunctional protein URA2; Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase; CPSase-ATCase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 15 papers)
41% identity, 99% coverage of query (295 bits)
P20054 Multifunctional protein pyr1-3; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Dictyostelium discoideum (Social amoeba)
43% identity, 98% coverage of query (293 bits)
CPA1 / P07258 carbamoyl phosphate synthetase (EC 6.3.5.5) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
CARA_YEAST / P07258 Carbamoyl phosphate synthase arginine-specific small chain; CPS; CPSase; CPSase-arg; Arginine-specific carbamoyl phosphate synthetase, glutamine chain; Carbamoyl phosphate synthase A; CPS-A; Glutamine-dependent carbamoyl phosphate synthetase; EC 6.3.5.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 9 papers)
43% identity, 100% coverage of query (290 bits)
pyrABCN protein pyrABCN [Includes glutamine-dependent carbamoyl-phosphate; Aspartate carbamoyltransferase]; EC 2.1.3.2; EC 6.3.5.5 from Emericella nidulans (see paper)
41% identity, 98% coverage of query (288 bits)
PYR1_DROME / P05990 Multifunctional protein r; Protein rudimentary; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Drosophila melanogaster (Fruit fly) (see paper)
43% identity, 98% coverage of query (283 bits)
PYR1_NEUCR / Q7S8A6 Multifunctional protein pyr-3; PyrABCN; Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase; CPSase-ATCase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 6 papers)
42% identity, 98% coverage of query (282 bits)
CPSM_RAT / P07756 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Rattus norvegicus (Rat) (see 2 papers)
41% identity, 98% coverage of query (278 bits)
5douD / P31327 Crystal structure of human carbamoyl phosphate synthetase i (cps1), ligand-bound form (see paper)
40% identity, 98% coverage of query (277 bits)
CPS1 / P31327 ammonia-dependent carbamoyl-phosphate synthase (EC 6.3.4.16) from Homo sapiens (see 4 papers)
CPSM_HUMAN / P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Homo sapiens (Human) (see 19 papers)
P31327 carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16) from Homo sapiens (see 10 papers)
40% identity, 98% coverage of query (277 bits)
6uelA / P31327 Cps1 bound to allosteric inhibitor h3b-193 (see paper)
40% identity, 98% coverage of query (277 bits)
6w2jB / P31327 Cps1 bound to allosteric inhibitor h3b-374 (see paper)
40% identity, 98% coverage of query (277 bits)
6w2jA Cps1 bound to allosteric inhibitor h3b-374
40% identity, 98% coverage of query (277 bits)
CPSM_MOUSE / Q8C196 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Mus musculus (Mouse) (see 4 papers)
Q8C196 carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16) from Mus musculus (see 2 papers)
41% identity, 98% coverage of query (276 bits)
CARX_GEOSE / P54324 Carbamoyl phosphate synthase arginine-specific small chain; Carbamoyl phosphate synthetase glutamine chain; EC 6.3.5.5 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see paper)
42% identity, 98% coverage of query (274 bits)
PYR1_SCHPO / Q09794 Multifunctional protein ura1; Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase; CPSase-ATCase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
ura1 / RF|NP_593055.1 carbamoyl-phosphate synthase (glutamine hydrolyzing), aspartate carbamoyltransferase Ura1; EC 2.1.3.2; EC 3.5.2.3; EC 6.3.5.5 from Schizosaccharomyces pombe (see 3 papers)
38% identity, 98% coverage of query (273 bits)
carA / CAA68238.2 carbamoyl-phosphate synthase small subunit from Lactobacillus plantarum subsp. plantarum (see 3 papers)
41% identity, 97% coverage of query (263 bits)
O15830 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Trypanosoma cruzi (see paper)
40% identity, 97% coverage of query (241 bits)
O15829 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Leishmania mexicana (see paper)
39% identity, 98% coverage of query (227 bits)
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Lawrence Berkeley National Laboratory