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Searching for up to 100 curated homologs for WP_012968949.1 NCBI__GCF_000025465.1:WP_012968949.1 (231 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AraD / b0061 L-ribulose-5-phosphate 4-epimerase AraD (EC 5.1.3.4) from Escherichia coli K-12 substr. MG1655 (see 19 papers)
araD / P08203 L-ribulose-5-phosphate 4-epimerase AraD (EC 5.1.3.4) from Escherichia coli (strain K12) (see 18 papers)
ARAD_ECOLI / P08203 L-ribulose-5-phosphate 4-epimerase AraD; Phosphoribulose isomerase; EC 5.1.3.4 from Escherichia coli (strain K12) (see 11 papers)
araD / GB|BAB96630.1 L-ribulose-5-phosphate 4-epimerase; EC 5.1.3.4 from Escherichia coli K12 (see paper)
    93% identity, 100% coverage of query (457 bits)

1jdiA / P08203 Crystal structure of l-ribulose-5-phosphate 4-epimerase (see paper)
    92% identity, 97% coverage of query (439 bits)

YiaS / b3583 L-ribulose-5-phosphate 4-epimerase SgbE (EC 5.1.3.4) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
sgbE / P37680 L-ribulose-5-phosphate 4-epimerase SgbE (EC 5.1.3.4) from Escherichia coli (strain K12) (see 3 papers)
SGBE_ECOLI / P37680 L-ribulose-5-phosphate 4-epimerase SgbE; Phosphoribulose isomerase; EC 5.1.3.4 from Escherichia coli (strain K12) (see 2 papers)
    74% identity, 100% coverage of query (365 bits)

YjfX / b4198 L-ribulose-5-phosphate 4-epimerase UlaF (EC 5.1.3.4) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
ulaF / P39306 L-ribulose-5-phosphate 4-epimerase UlaF (EC 5.1.3.4) from Escherichia coli (strain K12) (see paper)
ULAF_ECOLI / P39306 L-ribulose-5-phosphate 4-epimerase UlaF; L-ascorbate utilization protein F; Phosphoribulose isomerase; EC 5.1.3.4 from Escherichia coli (strain K12) (see 3 papers)
    59% identity, 100% coverage of query (293 bits)

ARAD_BACSU / P94525 L-ribulose-5-phosphate 4-epimerase; Phosphoribulose isomerase; EC 5.1.3.4 from Bacillus subtilis (strain 168) (see paper)
    58% identity, 100% coverage of query (275 bits)

Shewana3_2065 L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) from Shewanella sp. ANA-3
    51% identity, 99% coverage of query (243 bits)

CA265_RS08620 L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) from Pedobacter sp. GW460-11-11-14-LB5
    49% identity, 99% coverage of query (234 bits)

Echvi_0503 L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) from Echinicola vietnamensis KMM 6221, DSM 17526
    49% identity, 99% coverage of query (233 bits)

C4B4W3 L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) from Corynebacterium glutamicum (see paper)
    39% identity, 90% coverage of query (131 bits)

Build an alignment

Build an alignment for WP_012968949.1 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

drdA / P0DTQ0 5-deoxy-D-ribulose 1-phosphate aldolase (EC 4.1.2.62) from Bacillus thuringiensis serovar kurstaki (strain ATCC 35866 / NRRL B-4488 / HD73) (see paper)
DRDA_BACT7 / P0DTQ0 5-deoxy-D-ribulose 1-phosphate aldolase; 5-deoxyribose disposal aldolase; EC 4.1.2.- from Bacillus thuringiensis serovar kurstaki (strain ATCC 35866 / NRRL B-4488 / HD73) (see paper)
P0DTQ0 5-deoxyribulose 1-phosphate aldolase (EC 4.1.2.62) from Bacillus thuringiensis serovar kurstaki (see paper)
    29% identity, 100% coverage of query (82.4 bits)

6btgA Crystal structure of deoxyribose-phosphate aldolase bound with dhap from bacillus thuringiensis (see paper)
    30% identity, 89% coverage of query (82.0 bits)

ald2 / J7RCN0 5-deoxyribulose 1-phosphate aldolase (EC 4.1.2.62) from Escherichia coli (see paper)
    30% identity, 88% coverage of query (60.1 bits)

ALD2_ECO45 / B7MMH7 5-methylthioribulose-1-phosphate/5-deoxyribulose-1-phosphate aldolase; EC 4.1.2.62 from Escherichia coli O45:K1 (strain S88 / ExPEC) (see paper)
    31% identity, 88% coverage of query (59.3 bits)

MTNB_YEAST / P47095 Methylthioribulose-1-phosphate dehydratase; MTRu-1-P dehydratase; EC 4.2.1.109 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P47095 methylthioribulose 1-phosphate dehydratase (EC 4.2.1.109) from Saccharomyces cerevisiae (see paper)
    28% identity, 77% coverage of query (54.7 bits)

F8D9F5 D-ribulose 1-phosphate aldolase (EC 4.1.2.17) from Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) (see paper)
RU1PA_HALXS / F8D9F5 Ribulose-1-phosphate aldolase; Ru1P aldolase; EC 4.1.2.- from Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) (see paper)
    29% identity, 94% coverage of query (54.3 bits)

ald2 / Q2RXI1 5-(methylthio)ribulose-1-phosphate aldolase (EC 4.1.2.62) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) (see 2 papers)
ALD2_RHORT / Q2RXI1 5-methylthioribulose-1-phosphate/5-deoxyribulose-1-phosphate aldolase; EC 4.1.2.62 from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) (see 2 papers)
    27% identity, 92% coverage of query (50.1 bits)

MJ1418 / Q58813 fuculose-1-phosphate aldolase subunit (EC 4.1.2.17) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
FUCA_METJA / Q58813 L-fuculose phosphate aldolase; L-fuculose-1-phosphate aldolase; EC 4.1.2.17 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 3 papers)
Q58813 L-fuculose-phosphate aldolase (EC 4.1.2.17) from Methanocaldococcus jannaschii (see paper)
    24% identity, 84% coverage of query (47.8 bits)

6voqA / Q0QC76 Crystal structure of ygbl, a putative aldolase/epimerase/decarboxylase from klebsiella pneumoniae
    26% identity, 84% coverage of query (47.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory