Searching for up to 100 curated homologs for WP_012969728.1 NCBI__GCF_000025485.1:WP_012969728.1 (468 a.a.)
Found high-coverage hits (≥70%) to 45 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
argH / BAC65282.1 argininosuccinate lyase from Burkholderia multivorans (see paper)
64% identity, 96% coverage of query (593 bits)
ARLY_NOSS1 / Q8YQE6 Argininosuccinate lyase; ASAL; Arginosuccinase; NoArgH; EC 4.3.2.1 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see paper)
53% identity, 98% coverage of query (498 bits)
ARLY_SYNY3 / P73257 Argininosuccinate lyase; ASAL; Arginosuccinase; SyArgH; EC 4.3.2.1 from Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa) (see 2 papers)
52% identity, 98% coverage of query (490 bits)
ARLY_ARTPN / P0DXD4 Argininosuccinate lyase; ASAL; ArArgH; Arginosuccinase; EC 4.3.2.1 from Arthrospira platensis (strain NIES-39 / UTEX 3086 / IAM M-135) (Spirulina platensis) (see paper)
52% identity, 98% coverage of query (486 bits)
ARLY_NOSP7 / Q9LAE5 Argininosuccinate lyase; ASAL; ASL; Arginosuccinase; EC 4.3.2.1 from Nostoc punctiforme (strain ATCC 29133 / PCC 73102) (see paper)
Q9LAE5 argininosuccinate lyase (EC 4.3.2.1) from Nostoc sp. (see paper)
51% identity, 98% coverage of query (483 bits)
Q8DVX5 argininosuccinate lyase (EC 4.3.2.1) from Streptococcus mutans (see paper)
50% identity, 98% coverage of query (481 bits)
9ggjF / Q9LEU8 Crystal structure of argininosuccinate lyase from arabidopsis thaliana (atasl) in complex with biological substrate and products - argininosuccinate, argnine and fumarate (see paper)
52% identity, 97% coverage of query (465 bits)
9ggjA Crystal structure of argininosuccinate lyase from arabidopsis thaliana (atasl) in complex with biological substrate and products - argininosuccinate, argnine and fumarate
52% identity, 94% coverage of query (462 bits)
2e9fB / Q5SLL0 Crystal structure of t.Th.Hb8 argininosuccinate lyase complexed with l-arginine
50% identity, 95% coverage of query (434 bits)
ArgH / b3960 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
argH / P11447 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli (strain K12) (see 2 papers)
49% identity, 97% coverage of query (427 bits)
argH(A) / CAB95024.1 argininosuccinase and n-acetylglutamate synthase from Moritella abyssi (see paper)
47% identity, 97% coverage of query (421 bits)
1tj7B / P11447 Structure determination and refinement at 2.44 a resolution of argininosuccinate lyase from e. Coli (see paper)
49% identity, 96% coverage of query (420 bits)
Q9P870 argininosuccinate lyase (EC 4.3.2.1) from Agaricus bisporus (see paper)
47% identity, 97% coverage of query (419 bits)
ARLY2_ANAPL / P24058 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin II; Delta-2 crystallin; EC 4.3.2.1 from Anas platyrhynchos (Mallard) (Anas boschas) (see 6 papers)
44% identity, 98% coverage of query (395 bits)
ARLY_COLLI / Q01592 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Columba livia (Rock dove) (see 2 papers)
44% identity, 97% coverage of query (390 bits)
1k7wD / P24058 Crystal structure of s283a duck delta 2 crystallin mutant (see paper)
44% identity, 96% coverage of query (385 bits)
ARLY_ANSAN / P33110 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Anser anser anser (Western greylag goose) (see 2 papers)
43% identity, 98% coverage of query (383 bits)
arg7 / RF|NP_595129.1 argininosuccinate lyase; EC 4.3.2.1 from Schizosaccharomyces pombe (see paper)
43% identity, 97% coverage of query (380 bits)
ARLY1_ANAPL / P24057 Delta-1 crystallin; Delta crystallin I from Anas platyrhynchos (Mallard) (Anas boschas) (see 4 papers)
43% identity, 98% coverage of query (380 bits)
ARLY_YEAST / P04076 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
43% identity, 98% coverage of query (377 bits)
ARG7 / CAA09001.1 argininosuccinate lyase from Chlamydomonas reinhardtii (see paper)
44% identity, 99% coverage of query (375 bits)
ASL / P04424 argininosuccinate lyase (EC 4.3.2.1) from Homo sapiens (see 5 papers)
ARLY_HUMAN / P04424 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Homo sapiens (Human) (see 11 papers)
44% identity, 98% coverage of query (374 bits)
ARLY_MOUSE / Q91YI0 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Mus musculus (Mouse) (see paper)
44% identity, 98% coverage of query (372 bits)
1hy0A Crystal structure of wild type duck delta 1 crystallin (eye lens protein)
43% identity, 96% coverage of query (372 bits)
argH / CAA88927.2 argininosuccinate lyase from Streptomyces clavuligerus (see 3 papers)
46% identity, 97% coverage of query (369 bits)
ARLY1_CHICK / P02521 Delta-1 crystallin; Delta crystallin I from Gallus gallus (Chicken) (see 2 papers)
41% identity, 98% coverage of query (363 bits)
ARG4 argininosuccinate lyase from Candida albicans (see paper)
42% identity, 95% coverage of query (362 bits)
ARLY1_MELGA / Q7SIE0 Delta-1 crystallin; Delta crystallin I from Meleagris gallopavo (Wild turkey) (see paper)
41% identity, 98% coverage of query (360 bits)
P9WPY7 argininosuccinate lyase (EC 4.3.2.1) from Mycobacterium tuberculosis (see 2 papers)
46% identity, 99% coverage of query (351 bits)
AN2914 arginosuccinate lyase (Eurofung) from Emericella nidulans (see paper)
42% identity, 94% coverage of query (343 bits)
6ienB / P9WPY7 Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis (see paper)
47% identity, 96% coverage of query (343 bits)
6ienA Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis
46% identity, 96% coverage of query (334 bits)
6ienC Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis
44% identity, 96% coverage of query (321 bits)
CA265_RS18485 arginosuccinate lyase (EC 4.3.2.1) from Pedobacter sp. GW460-11-11-14-LB5
35% identity, 82% coverage of query (236 bits)
Echvi_3852 arginosuccinate lyase (EC 4.3.2.1) from Echinicola vietnamensis KMM 6221, DSM 17526
38% identity, 81% coverage of query (233 bits)
6g3fA / Q11KV9 Crystal structure of edds lyase in complex with fumarate (see paper)
35% identity, 95% coverage of query (226 bits)
6g3iA Crystal structure of edds lyase in complex with n-(2-aminoethyl) aspartic acid (aeaa)
35% identity, 95% coverage of query (226 bits)
6g3hA Crystal structure of edds lyase in complex with ss-edds
35% identity, 95% coverage of query (226 bits)
6g3gA Crystal structure of edds lyase in complex with succinate
35% identity, 95% coverage of query (226 bits)
BT3733 arginosuccinate lyase (EC 4.3.2.1) from Bacteroides thetaiotaomicron VPI-5482
36% identity, 84% coverage of query (223 bits)
ABZR86_RS08695 arginosuccinate lyase (EC 4.3.2.1) from Dyella japonica UNC79MFTsu3.2
34% identity, 79% coverage of query (183 bits)
Build an alignment for WP_012969728.1 and 41 homologs with ≥ 30% identity
Or download the sequences
MJ0929 / Q58339 adenylosuccinate lyase (EC 4.3.2.2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
28% identity, 75% coverage of query (88.6 bits)
pcaB2 / Q2HNY9 3-carboxymuconate lactonizing enzyme type 2 (EC 5.5.1.2) from Hydrogenophaga intermedia (see 2 papers)
24% identity, 78% coverage of query (68.2 bits)
pcaB / AAC37149.1 beta-carboxy-cis,cis-muconate cycloisomerase from Acinetobacter baylyi (see 11 papers)
22% identity, 83% coverage of query (66.2 bits)
creD / A0A0K2JL82 nitrosuccinate lyase (EC 4.3.99.5) from Streptomyces cremeus (see paper)
CRED_STRCM / A0A0K2JL82 Nitrosuccinate lyase; EC 4.3.99.5 from Streptomyces cremeus (see 3 papers)
A0A0K2JL82 nitrosuccinate lyase (EC 4.3.99.5) from Streptomyces cremeus (see paper)
25% identity, 74% coverage of query (44.7 bits)
Or start over
Lawrence Berkeley National Laboratory