Searching for up to 100 curated homologs for WP_012973715.1 NCBI__GCF_000010725.1:WP_012973715.1 (434 a.a.)
Found high-coverage hits (≥70%) to 26 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Ga0059261_2711 homoserine dehydrogenase (EC 1.1.1.3) from Sphingomonas koreensis DSMZ 15582
55% identity, 98% coverage of query (429 bits)
DHOM_NEIG1 / Q5F8J4 Homoserine dehydrogenase; HDH; HSD; NAD(+)-dependent homoserine dehydrogenase; NAD(+)-dependent HSD; NgHSD; EC 1.1.1.3 from Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) (see paper)
48% identity, 94% coverage of query (373 bits)
hom / AAF21129.1 homoserine dehydrogenase from Methylobacillus flagellatus (see paper)
45% identity, 98% coverage of query (350 bits)
DvMF_1412 homoserine dehydrogenase (EC 1.1.1.3) from Desulfovibrio vulgaris Miyazaki F
42% identity, 98% coverage of query (310 bits)
6dzsA / K5BJC9 Mycobacterial homoserine dehydrogenase thra in complex with NADP
44% identity, 98% coverage of query (286 bits)
D8WXQ1 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
36% identity, 98% coverage of query (280 bits)
DHOM_BACSU / P19582 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Bacillus subtilis (strain 168) (see 3 papers)
P19582 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus subtilis (see paper)
36% identity, 98% coverage of query (270 bits)
DHOM_CORGL / P08499 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 2 papers)
P08499 homoserine dehydrogenase (EC 1.1.1.3) from Corynebacterium glutamicum (see 2 papers)
40% identity, 97% coverage of query (268 bits)
Q56R01 homoserine dehydrogenase (EC 1.1.1.3) from Streptomyces clavuligerus (see paper)
39% identity, 98% coverage of query (254 bits)
P46806 homoserine dehydrogenase (EC 1.1.1.3) from Mycobacterium leprae (see paper)
40% identity, 97% coverage of query (248 bits)
DHOM_LACLC / P52985 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Lactococcus lactis subsp. cremoris (Streptococcus cremoris) (see paper)
37% identity, 92% coverage of query (244 bits)
A0A0H2WVX4 homoserine dehydrogenase (EC 1.1.1.3) from Staphylococcus aureus (see 2 papers)
39% identity, 73% coverage of query (236 bits)
D8WXQ2 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
37% identity, 75% coverage of query (217 bits)
4pg7A / A0A0M3KKV6 Crystal structure of s. Aureus homoserine dehydrogenase at ph7.5 (see paper)
37% identity, 74% coverage of query (213 bits)
Q9WZ17 homoserine dehydrogenase (EC 1.1.1.3); aspartate kinase (EC 2.7.2.4) from Thermotoga maritima (see paper)
40% identity, 75% coverage of query (196 bits)
7f4cA The crystal structure of the immature holo-enzyme of homoserine dehydrogenase complexed with NADP and 1,4-butandiol from the hyperthermophilic archaeon sulfurisphaera tokodaii.
32% identity, 73% coverage of query (122 bits)
DHOM_SULTO / F9VNG5 Homoserine dehydrogenase; HDH; HSD; StHSD; EC 1.1.1.3 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see 3 papers)
F9VNG5 homoserine dehydrogenase (EC 1.1.1.3) from Sulfurisphaera tokodaii (see paper)
32% identity, 73% coverage of query (121 bits)
5x9dA / F9VNG5 Crystal structure of homoserine dehydrogenase in complex with l- cysteine and NAD (see paper)
32% identity, 73% coverage of query (120 bits)
Build an alignment for WP_012973715.1 and 18 homologs with ≥ 30% identity
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DHOM_PYRHO / O58802 Homoserine dehydrogenase; HDH; HSD; HseDH; EC 1.1.1.3 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
O58802 homoserine dehydrogenase (EC 1.1.1.3) from Pyrococcus horikoshii (see paper)
4xb1A / O58802 Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH (see paper)
28% identity, 72% coverage of query (101 bits)
4xb2A Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH
28% identity, 72% coverage of query (101 bits)
Q5AIA2 homoserine dehydrogenase (EC 1.1.1.3) from Candida albicans (see 2 papers)
28% identity, 73% coverage of query (81.3 bits)
Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) from Echinicola vietnamensis KMM 6221, DSM 17526
24% identity, 72% coverage of query (75.5 bits)
O63067 homoserine dehydrogenase (EC 1.1.1.3) from Glycine max (see paper)
25% identity, 74% coverage of query (75.5 bits)
AKH2_ARATH / O81852 Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic; AK-HD 2; AK-HSDH 2; Beta-aspartyl phosphate homoserine 2; EC 2.7.2.4; EC 1.1.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
25% identity, 74% coverage of query (75.1 bits)
AAA16972.1 aspartokinase-homoserine dehydrogenase, partial from Daucus carota (see paper)
25% identity, 74% coverage of query (70.1 bits)
MetM / b3940 fused aspartate kinase/homoserine dehydrogenase 2 (EC 2.7.2.4; EC 1.1.1.3) from Escherichia coli K-12 substr. MG1655 (see paper)
metL / P00562 fused aspartate kinase/homoserine dehydrogenase 2 (EC 2.7.2.4; EC 1.1.1.3) from Escherichia coli (strain K12) (see 9 papers)
27% identity, 73% coverage of query (62.8 bits)
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Lawrence Berkeley National Laboratory