Searching for up to 100 curated homologs for WP_012974739.1 NCBI__GCF_000010725.1:WP_012974739.1 (587 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ilvB / Q0KCU4 acetohydroxyacid synthase subunit B (EC 2.2.1.6) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
54% identity, 97% coverage of query (649 bits)
P45261 acetolactate synthase (EC 2.2.1.6) from Haemophilus influenzae (see paper)
49% identity, 97% coverage of query (603 bits)
IlvI / b0077 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ilvI / P00893 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli (strain K12) (see 7 papers)
P00893 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
50% identity, 96% coverage of query (585 bits)
G0ZSE6 acetolactate synthase (EC 2.2.1.6) from Pseudomonas sp. (see paper)
51% identity, 94% coverage of query (584 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
51% identity, 97% coverage of query (577 bits)
Q5SJ01 acetolactate synthase (EC 2.2.1.6); pyruvate decarboxylase (EC 4.1.1.1) from Thermus thermophilus (see paper)
49% identity, 97% coverage of query (550 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
49% identity, 96% coverage of query (549 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
48% identity, 96% coverage of query (537 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
45% identity, 96% coverage of query (524 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
47% identity, 96% coverage of query (523 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
47% identity, 96% coverage of query (511 bits)
Q5VB49 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
46% identity, 96% coverage of query (500 bits)
Q5VB44 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
45% identity, 96% coverage of query (498 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
44% identity, 96% coverage of query (497 bits)
5k2oA / P17597 Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, pyrithiobac (see paper)
44% identity, 96% coverage of query (496 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
44% identity, 96% coverage of query (496 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
44% identity, 96% coverage of query (496 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
44% identity, 96% coverage of query (496 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
44% identity, 96% coverage of query (496 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
44% identity, 96% coverage of query (496 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
44% identity, 96% coverage of query (496 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
44% identity, 96% coverage of query (496 bits)
1yhzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
44% identity, 96% coverage of query (496 bits)
1yhyA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
44% identity, 96% coverage of query (496 bits)
1ybhA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide chlorimuron ethyl
44% identity, 96% coverage of query (496 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
44% identity, 96% coverage of query (496 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
44% identity, 96% coverage of query (495 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
44% identity, 96% coverage of query (495 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
45% identity, 96% coverage of query (493 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
44% identity, 96% coverage of query (493 bits)
ILV2 acetolactate synthase; EC 2.2.1.6 from Candida albicans (see paper)
44% identity, 96% coverage of query (491 bits)
Q42768 acetolactate synthase (EC 2.2.1.6) from Gossypium hirsutum (see paper)
45% identity, 96% coverage of query (490 bits)
Q5VB42 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
44% identity, 96% coverage of query (489 bits)
V5Q0Z4 acetolactate synthase (EC 2.2.1.6) from Myosoton aquaticum (see paper)
44% identity, 96% coverage of query (489 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
45% identity, 97% coverage of query (488 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
45% identity, 97% coverage of query (488 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
45% identity, 97% coverage of query (487 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
45% identity, 97% coverage of query (487 bits)
6demA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl
44% identity, 96% coverage of query (487 bits)
6delA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl
44% identity, 96% coverage of query (487 bits)
6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam
44% identity, 96% coverage of query (487 bits)
6desA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone
44% identity, 96% coverage of query (487 bits)
6depA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl
44% identity, 96% coverage of query (487 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
45% identity, 97% coverage of query (487 bits)
6deqA / A0A1D8PJF9 Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam (see paper)
44% identity, 96% coverage of query (486 bits)
6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl
44% identity, 96% coverage of query (486 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
44% identity, 96% coverage of query (486 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
45% identity, 97% coverage of query (485 bits)
6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl
45% identity, 96% coverage of query (484 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
44% identity, 96% coverage of query (484 bits)
1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
45% identity, 97% coverage of query (483 bits)
ilvB / AAA93098.1 acetolactate synthase from Streptomyces avermitilis (see paper)
43% identity, 99% coverage of query (481 bits)
CFOL_ASPCN / A0A2I2F2I5 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; Chlorflavonin biosynthesis cluster protein L; EC 2.2.1.6 from Aspergillus candidus (see paper)
46% identity, 97% coverage of query (479 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
45% identity, 97% coverage of query (479 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
45% identity, 97% coverage of query (479 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
45% identity, 97% coverage of query (479 bits)
7egvA Acetolactate synthase from trichoderma harzianum with inhibitor harzianic acid (see paper)
46% identity, 96% coverage of query (475 bits)
6dekA Crystal structure of candida albicans acetohydroxyacid synthase catalytic subunit
44% identity, 96% coverage of query (472 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
43% identity, 97% coverage of query (468 bits)
A0A0M4NDK0 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
43% identity, 96% coverage of query (467 bits)
A5X300 acetolactate synthase (EC 2.2.1.6) from Oryza sativa Indica Group (see paper)
42% identity, 96% coverage of query (464 bits)
Q6K2E8 acetolactate synthase (EC 2.2.1.6) from Oryza sativa (see paper)
42% identity, 96% coverage of query (464 bits)
A0A0M3TGF7 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
43% identity, 96% coverage of query (464 bits)
K7TWQ8 acetolactate synthase (EC 2.2.1.6) from Zea mays (see paper)
43% identity, 96% coverage of query (462 bits)
AN4956 acetolactate synthase; EC 2.2.1.6 from Emericella nidulans (see paper)
43% identity, 96% coverage of query (462 bits)
G4MMK2 acetolactate synthase (subunit 1/2) (EC 2.2.1.6) from Pyricularia oryzae (see paper)
44% identity, 96% coverage of query (460 bits)
ilv1 / RF|NP_595382.1 acetolactate synthase catalytic subunit; EC 2.2.1.6 from Schizosaccharomyces pombe (see 2 papers)
43% identity, 96% coverage of query (449 bits)
6vz8D / P17597 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
44% identity, 93% coverage of query (446 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
44% identity, 93% coverage of query (443 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
44% identity, 93% coverage of query (443 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
44% identity, 93% coverage of query (442 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
44% identity, 93% coverage of query (441 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
41% identity, 95% coverage of query (440 bits)
6wo1A / Q96VZ6 Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit (see paper)
43% identity, 96% coverage of query (436 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
40% identity, 97% coverage of query (422 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
40% identity, 97% coverage of query (420 bits)
PS417_08810 glyoxylate carboligase (EC 4.1.1.47) from Pseudomonas simiae WCS417
35% identity, 94% coverage of query (327 bits)
Gcl / b0507 glyoxylate carboligase (EC 4.1.1.47) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
gcl / P0AEP7 glyoxylate carboligase (EC 4.1.1.47) from Escherichia coli (strain K12) (see 6 papers)
P0AEP7 tartronate-semialdehyde synthase (EC 4.1.1.47) from Escherichia coli K-12 (see paper)
gcl / ECOCYC|GLYOCARBOLIG-MONOMER glyoxylate carboligase; EC 4.1.1.47 from Escherichia coli K12 (see 5 papers)
gcl / AAA23864.1 glyoxylate carboligase from Escherichia coli (see paper)
33% identity, 94% coverage of query (319 bits)
8i01A / P0AEP7 Crystal structure of escherichia coli glyoxylate carboligase (see paper)
33% identity, 94% coverage of query (318 bits)
8beoB Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
33% identity, 94% coverage of query (318 bits)
8beoA Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
33% identity, 94% coverage of query (318 bits)
8i07D Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
33% identity, 94% coverage of query (317 bits)
8i07A Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
33% identity, 94% coverage of query (317 bits)
Psest_1181 Glyoxylate carboligase (EC 4.1.1.47) from Pseudomonas stutzeri RCH2
33% identity, 92% coverage of query (311 bits)
5ahkA / Q4K6F7 Crystal structure of acetohydroxy acid synthase pf5 from pseudomonas protegens
30% identity, 95% coverage of query (241 bits)
Build an alignment for WP_012974739.1 and 85 homologs with ≥ 30% identity
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8rpjA Janthe from janthinobacterium sp. Hh01
27% identity, 99% coverage of query (218 bits)
8rpiA Janthe from janthinobacterium sp. Hh01, lactyl-thdp
27% identity, 99% coverage of query (218 bits)
8rphD 8rphD (see paper)
28% identity, 95% coverage of query (218 bits)
4rjiC Acetolactate synthase from bacillus subtilis bound to thdp - crystal form i (see paper)
30% identity, 94% coverage of query (211 bits)
4rjkG Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
30% identity, 93% coverage of query (211 bits)
4rjkF Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
30% identity, 93% coverage of query (211 bits)
5d6rB Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor
30% identity, 94% coverage of query (202 bits)
5dx6B / P27696 Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
30% identity, 96% coverage of query (201 bits)
1ozgA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
30% identity, 94% coverage of query (201 bits)
1ozfA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
30% identity, 94% coverage of query (200 bits)
5wdgA Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate
30% identity, 94% coverage of query (195 bits)
1powA The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from lactobacillus plantarum
28% identity, 93% coverage of query (194 bits)
4feeA High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal b (see paper)
28% identity, 93% coverage of query (194 bits)
3ey9A / P07003 Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from escherichia coli (see paper)
28% identity, 94% coverage of query (193 bits)
PoxB / b0871 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli K-12 substr. MG1655 (see 70 papers)
poxB / P07003 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli (strain K12) (see 69 papers)
POXB_ECOLI / P07003 Pyruvate dehydrogenase [ubiquinone]; Pyruvate oxidase; POX; Pyruvate:ubiquinone-8 oxidoreductase; EC 1.2.5.1 from Escherichia coli (strain K12) (see 13 papers)
P07003 pyruvate dehydrogenase (quinone) (EC 1.2.5.1) from Escherichia coli (see paper)
28% identity, 94% coverage of query (193 bits)
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