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Searching for up to 100 curated homologs for WP_013074321.1 NCBI__GCF_000092905.1:WP_013074321.1 (318 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

F0QW25 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Vulcanisaeta moutnovskia (see 2 papers)
    45% identity, 94% coverage of query (291 bits)

F2L0W0 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermoproteus uzoniensis (see 3 papers)
    45% identity, 94% coverage of query (268 bits)

6thqB / F2L0W0 Crystal structure of branched-chain aminotransferase from thermophilic archaea thermoproteus uzoniensis with norvaline
    45% identity, 94% coverage of query (268 bits)

B9L0B7 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermomicrobium roseum (see paper)
    43% identity, 94% coverage of query (237 bits)

2ej0B / Q5SM19 Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase with pyridoxamine 5'-phosphate
    39% identity, 95% coverage of query (229 bits)

2ej3A Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with gabapentin
    39% identity, 95% coverage of query (228 bits)

2eiyA Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with 4-methylvaleric acid
    39% identity, 95% coverage of query (228 bits)

1wrvA Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase
    39% identity, 95% coverage of query (228 bits)

D1CCW1 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermobaculum terrenum (see paper)
    39% identity, 96% coverage of query (227 bits)

6h65C / D0LR31 Crystal structure of the branched-chain-amino-acid aminotransferase from haliangium ochraceum
    39% identity, 94% coverage of query (226 bits)

D0LR31 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Haliangium ochraceum (see paper)
    39% identity, 94% coverage of query (226 bits)

6q8eA Crystal structure of branched-chain amino acid aminotransferase from thermobaculum terrenum in pmp-form
    39% identity, 94% coverage of query (226 bits)

2ej2A Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate
    39% identity, 95% coverage of query (225 bits)

7neaA / D1CCW1 Crystal structure of branched-chain amino acid aminotransferase from thermobaculum terrenum (m3 mutant). (see paper)
    38% identity, 94% coverage of query (218 bits)

P54691 branched-chain-amino-acid transaminase (EC 2.6.1.42); glutamate-prephenate aminotransferase (EC 2.6.1.79) from Synechocystis sp. (see paper)
    37% identity, 92% coverage of query (216 bits)

BPHYT_RS16285 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Burkholderia phytofirmans PsJN
    39% identity, 94% coverage of query (216 bits)

4whxA X-ray crystal structure of an amino acid aminotransferase from burkholderia pseudomallei bound to the co-factor pyridoxal phosphate
    40% identity, 94% coverage of query (216 bits)

A6UP94 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Methanococcus vannielii (see paper)
    38% identity, 93% coverage of query (215 bits)

Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Pseudomonas stutzeri RCH2
    40% identity, 94% coverage of query (213 bits)

ilvE / O27481 branched-chain-amino-acid aminotransferase subunit (EC 2.6.1.42) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see 3 papers)
    38% identity, 94% coverage of query (213 bits)

ilvE / O86428 branched-chain-amino-acid aminotransferase subunit (EC 2.6.1.6; EC 2.6.1.42) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 4 papers)
O86428 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Pseudomonas aeruginosa (see paper)
    38% identity, 94% coverage of query (209 bits)

IlvE / b3770 branched-chain-amino-acid aminotransferase (EC 2.6.1.1; EC 2.6.1.57; EC 2.6.1.27; EC 2.6.1.42; EC 2.6.1.6) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ilvE / P0AB80 branched-chain-amino-acid aminotransferase (EC 2.6.1.1; EC 2.6.1.42; EC 2.6.1.6) from Escherichia coli (strain K12) (see paper)
ilvE / RF|YP_026247 branched-chain-amino-acid aminotransferase; EC 2.6.1.42 from Escherichia coli K12 (see 11 papers)
    39% identity, 94% coverage of query (209 bits)

1i1lA / P0AB80 Crystal structure of eschelichia coli branched-chain amino acid aminotransferase. (see paper)
    39% identity, 94% coverage of query (208 bits)

1iyeA Crystal structure of eschelichia coli branched-chain amino acid aminotransferase
    39% identity, 94% coverage of query (208 bits)

1iydA Crystal structure of eschelichia coli branched-chain amino acid aminotransferase
    39% identity, 94% coverage of query (208 bits)

1i1mA Crystal structure of escherichia coli branched-chain amino acid aminotransferase.
    39% identity, 94% coverage of query (208 bits)

ABZR86_RS11580 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Dyella japonica UNC79MFTsu3.2
    38% identity, 94% coverage of query (207 bits)

5mr0D / O29329 Thermophilic archaeal branched-chain amino acid transaminases from geoglobus acetivorans and archaeoglobus fulgidus: biochemical and structural characterisation (see paper)
    39% identity, 87% coverage of query (179 bits)

5e25A / A0A0A7GJ30 Crystal structure of branched-chain aminotransferase from thermophilic archaea geoglobus acetivorans complexed with alpha-ketoglutarate (see paper)
    37% identity, 88% coverage of query (167 bits)

GB|AAU18968.1 branched-chain amino acid aminotransferase 2; EC 2.6.1.42 from Bacillus cereus E33L (see paper)
    34% identity, 89% coverage of query (152 bits)

A0A1B1L2T7 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Bacillus thuringiensis (see paper)
    34% identity, 89% coverage of query (150 bits)

E6TUA8 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Evansella cellulosilytica (see paper)
    32% identity, 91% coverage of query (144 bits)

ilvE / A6UWA0 branched-chain amino acid aminotransferase subunit (EC 2.6.1.6; EC 2.6.1.42) from Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3) (see 3 papers)
A6UWA0 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Methanococcus aeolicus (see paper)
    32% identity, 89% coverage of query (142 bits)

A0A0A0LJI6 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Cucumis sativus var. sativus (see paper)
    31% identity, 86% coverage of query (115 bits)

Build an alignment

Build an alignment for WP_013074321.1 and 34 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

BCAT3 / Q9M401 branched-chain aminotransferase from Arabidopsis thaliana (see paper)
BCAT3_ARATH / Q9M401 Branched-chain-amino-acid aminotransferase 3, chloroplastic; Atbcat-3; EC 2.6.1.42; EC 2.6.1.88 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9M401 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see paper)
    27% identity, 92% coverage of query (114 bits)

Q9FYA6 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see paper)
    26% identity, 92% coverage of query (109 bits)

6xu3C (R)-selective amine transaminase from shinella sp. (see paper)
    28% identity, 93% coverage of query (109 bits)

BCAT2_HUMLU / K7QHS5 Branched-chain amino acid aminotransferase 2, chloroplastic; HlBCAT2; EC 2.6.1.42 from Humulus lupulus (European hop) (see paper)
    27% identity, 93% coverage of query (108 bits)

6xu3B (R)-selective amine transaminase from shinella sp.
    28% identity, 93% coverage of query (108 bits)

6xu3A (R)-selective amine transaminase from shinella sp.
    28% identity, 93% coverage of query (108 bits)

A0A0A0KG15 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Cucumis sativus var. sativus (see paper)
    29% identity, 94% coverage of query (107 bits)

6snlD / A0A0D1XFW6 (R)-selective amine transaminase from exophiala sideris (see paper)
    26% identity, 93% coverage of query (106 bits)

3cswC / P74921 Crystal structure of a putative branched-chain amino acid aminotransferase (tm0831) from thermotoga maritima at 2.15 a resolution
    32% identity, 76% coverage of query (103 bits)

Q9LPM9 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see 2 papers)
    28% identity, 82% coverage of query (100 bits)

B6RFK8 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Nicotiana benthamiana (see paper)
    29% identity, 88% coverage of query (100 bits)

Q70KX9 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Hordeum vulgare (see paper)
    29% identity, 81% coverage of query (97.1 bits)

8ivpB / A1TDP1 Crystal structure of mv in complex with llp and fru from mycobacterium vanbaalenii
    28% identity, 90% coverage of query (97.1 bits)

ilvE / O31461 branched-chain amino acid aminotransferase (EC 2.6.1.6; EC 2.6.1.42) from Bacillus subtilis (strain 168) (see 4 papers)
ILVE1_BACSU / O31461 Branched-chain-amino-acid transaminase 1; BCAT 1; EC 2.6.1.42 from Bacillus subtilis (strain 168) (see paper)
    28% identity, 88% coverage of query (96.7 bits)

4cmdA / C7YVL8 The (r)-selective transaminase from nectria haematococca (see paper)
    25% identity, 94% coverage of query (96.7 bits)

4cmfA The (r)-selective transaminase from nectria haematococca with inhibitor bound
    25% identity, 94% coverage of query (96.7 bits)

RR42_RS25890 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Cupriavidus basilensis FW507-4G11
    32% identity, 83% coverage of query (94.7 bits)

4ce5A / Q0C8G1 First crystal structure of an (r)-selective omega-transaminase from aspergillus terreus (see paper)
    25% identity, 97% coverage of query (94.7 bits)

4ce5B First crystal structure of an (r)-selective omega-transaminase from aspergillus terreus
    25% identity, 97% coverage of query (94.7 bits)

BCAT4 / Q9LE06 methionine transaminase (EC 2.6.1.88) from Arabidopsis thaliana (see paper)
BCAT4_ARATH / Q9LE06 Methionine aminotransferase BCAT4; Branched-chain-amino-acid aminotransferase 4; Atbcat-4; Methionine-oxo-acid transaminase BCAT4; EC 2.6.1.88 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9LE06 branched-chain-amino-acid transaminase (EC 2.6.1.42); methionine transaminase (EC 2.6.1.88) from Arabidopsis thaliana (see 2 papers)
    29% identity, 82% coverage of query (94.4 bits)

Q93Y32 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see paper)
    26% identity, 93% coverage of query (94.0 bits)

A0A0A0LN48 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Cucumis sativus var. sativus (see paper)
    30% identity, 82% coverage of query (93.6 bits)

ATNJ_EMENI / Q5AV04 Aminotransferase atnJ; Aspercryptin biosynthesis cluster protein J; EC 2.6.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 3 papers)
    29% identity, 76% coverage of query (93.6 bits)

7p3tB / B8KQT8 Transaminase of gamma-proteobacterium (see paper)
    25% identity, 88% coverage of query (92.8 bits)

DAAA_BACYM / P19938 D-alanine aminotransferase; D-amino acid aminotransferase; D-amino acid transaminase; DAAT; D-aspartate aminotransferase; EC 2.6.1.21 from Bacillus sp. (strain YM-1) (see 3 papers)
dat D-alanine aminotransferase; EC 2.6.1.21 from Bacillus sp. YM-1 (see 6 papers)
    26% identity, 88% coverage of query (92.4 bits)

7dbeB Structure of a novel transaminase
    24% identity, 95% coverage of query (92.4 bits)

3daaA Crystallographic structure of d-amino acid aminotransferase inactivated by pyridoxyl-d-alanine
    26% identity, 88% coverage of query (92.4 bits)

2daaA Crystallographic structure of d-amino acid aminotransferase inactivated by d-cycloserine
    26% identity, 88% coverage of query (92.4 bits)

1daaA Crystallographic structure of d-amino acid aminotransferase complexed with pyridoxal-5'-phosphate
    26% identity, 88% coverage of query (92.4 bits)

3lqsA Complex structure of d-amino acid aminotransferase and 4-amino-4,5- dihydro-thiophenecarboxylic acid (adta)
    26% identity, 88% coverage of query (92.4 bits)

6xwbA Crystal structure of an r-selective transaminase from thermomyces stellatus. (see paper)
    26% identity, 93% coverage of query (92.0 bits)

6fteB / A0A0D2C5V9 Crystal structure of an (r)-selective amine transaminase from exophiala xenobiotica
    23% identity, 92% coverage of query (91.7 bits)

7z79B / T1XIY1 Crystal structure of aminotransferase-like protein from variovorax paradoxus
    26% identity, 93% coverage of query (90.1 bits)

1a0gB / P19938 L201a mutant of d-amino acid aminotransferase complexed with pyridoxamine-5'-phosphate (see paper)
    25% identity, 88% coverage of query (90.1 bits)

Q0E9S8 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Helicobacter pylori (see paper)
    27% identity, 92% coverage of query (89.4 bits)

O26004 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Helicobacter pylori (see paper)
    28% identity, 87% coverage of query (89.0 bits)

POXL_PENOX / A0A1W5T1Y5 Aminotransferase poxL; Oxaleimides biosynthesis cluster protein L; EC 2.6.1.- from Penicillium oxalicum (see paper)
    26% identity, 90% coverage of query (89.0 bits)

POXL_PENO1 / S7ZEI5 Aminotransferase poxL; Oxaleimides biosynthesis cluster protein L; EC 2.6.1.- from Penicillium oxalicum (strain 114-2 / CGMCC 5302) (Penicillium decumbens) (see paper)
    26% identity, 90% coverage of query (87.0 bits)

Q9RTX5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Deinococcus radiodurans (see paper)
    29% identity, 87% coverage of query (86.7 bits)

3uyyB / Q9RTX5 Crystal structures of branched-chain aminotransferase from deinococcus radiodurans complexes with alpha-ketoisocaproate and l-glutamate suggest its radio-resistance for catalysis (see paper)
    29% identity, 87% coverage of query (86.7 bits)

3uzoA Crystal structures of branched-chain aminotransferase from deinococcus radiodurans complexes with alpha-ketoisocaproate and l-glutamate suggest its radio-resistance for catalysis
    29% identity, 87% coverage of query (86.7 bits)

3uzbA Crystal structures of branched-chain aminotransferase from deinococcus radiodurans complexes with alpha-ketoisocaproate and l-glutamate suggest its radio-resistance for catalysis
    29% identity, 87% coverage of query (86.7 bits)

A0A5Q8BPF5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Lacticaseibacillus paracasei (see paper)
    27% identity, 86% coverage of query (86.3 bits)

BCAT1_HUMLU / K7QKH1 Branched-chain amino acid aminotransferase 1, mitochondrial; HlBCAT1; EC 2.6.1.42 from Humulus lupulus (European hop) (see paper)
    29% identity, 75% coverage of query (85.9 bits)

A0A2Z4MEX9 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Brevibacillus brevis (see paper)
    26% identity, 85% coverage of query (82.8 bits)

Q5FTR3 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Gluconobacter oxydans (see paper)
    28% identity, 91% coverage of query (81.3 bits)

BCAT2_ARATH / Q9M439 Branched-chain-amino-acid aminotransferase 2, chloroplastic; Atbcat-2; EC 2.6.1.42 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9M439 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see paper)
    25% identity, 93% coverage of query (80.5 bits)

Q7BPX6 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Lactococcus lactis (see paper)
    28% identity, 92% coverage of query (80.1 bits)

AO356_22970 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Pseudomonas fluorescens FW300-N2C3
    27% identity, 87% coverage of query (79.7 bits)

dat / P54693 D-alanine aminotransferase monomer (EC 2.6.1.21) from Lysinibacillus sphaericus (see 7 papers)
    25% identity, 88% coverage of query (79.3 bits)

8aieB Crystal structure of d-amino acid aminotransferase from aminobacterium colombiense complexed with d-cycloserine
    26% identity, 89% coverage of query (79.3 bits)

8aykA Crystal structure of d-amino acid aminotrensferase from aminobacterium colombiense complexed with d-glutamate
    26% identity, 89% coverage of query (79.3 bits)

8ayjA Crystal structure of d-amino acid aminotransferase from aminobacterium colombiens complexed with 3-aminooxypropionic acid
    26% identity, 89% coverage of query (79.3 bits)

8aieA Crystal structure of d-amino acid aminotransferase from aminobacterium colombiense complexed with d-cycloserine
    26% identity, 89% coverage of query (79.3 bits)

8raiA Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis point mutant r90i complexed with phenylhydrazine
    25% identity, 90% coverage of query (78.6 bits)

4chiA / Q4WH08 (R)-selective amine transaminase from aspergillus fumigatus at 1.27 a resolution (see paper)
    24% identity, 93% coverage of query (77.4 bits)

6jifB Crystal structures of branched-chain aminotransferase from pseudomonas sp. Uw4 (see paper)
    27% identity, 87% coverage of query (77.4 bits)

8ahuA / F4KWH0 Crystal structure of d-amino acid aminotrensferase from haliscomenobacter hydrossis complexed with d-cycloserine (see paper)
    26% identity, 90% coverage of query (77.4 bits)

4uugA The (r)-selective amine transaminase from aspergillus fumigatus with inhibitor bound
    24% identity, 93% coverage of query (77.4 bits)

pabC / P28821 4-amino-4-deoxychorismate pyruvate-lyase (EC 4.1.3.38) from Bacillus subtilis (strain 168) (see paper)
PABC_BACSU / P28821 Aminodeoxychorismate lyase; 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL; EC 4.1.3.38 from Bacillus subtilis (strain 168) (see paper)
    25% identity, 92% coverage of query (77.0 bits)

7p7xA Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis (holo form).
    26% identity, 90% coverage of query (77.0 bits)

8onjA / D5EHC5 Crystal structure of d-amino acid aminotransferase from aminobacterium colombiense point mutant r88l (see paper)
    26% identity, 89% coverage of query (76.6 bits)

8yrvA Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis complexed with 3-aminooxypropionic acid
    26% identity, 90% coverage of query (76.3 bits)

ilvK / P39576 branched-chain amino acid aminotransferase (EC 2.6.1.42; EC 2.6.1.6) from Bacillus subtilis (strain 168) (see 2 papers)
ILVE2_BACSU / P39576 Branched-chain-amino-acid aminotransferase 2; BCAT 2; Vegetative protein 85; VEG85; EC 2.6.1.42 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 86% coverage of query (74.7 bits)

ATNH_EMENI / Q5AV02 Branched-chain-amino-acid aminotransferase atnH; Aspercryptin biosynthesis cluster protein H; EC 2.6.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 3 papers)
    29% identity, 80% coverage of query (74.3 bits)

HtyB / K0E3V3 4-(4-hydroxyphenyl)-2-oxobutanoate transaminase from Aspergillus rugulosus (see paper)
HTYB_ASPRU / K0E3V3 Transaminase htyB; L-homotyrosine biosynthetic cluster protein B; EC 2.6.1.- from Aspergillus rugulosus (Emericella rugulosa) (see paper)
    27% identity, 81% coverage of query (74.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory