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Searching for up to 100 curated homologs for WP_013259992.1 NCBI__GCF_000143965.1:WP_013259992.1 (109 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

P80524 pyruvate synthase (subunit 1/4) (EC 1.2.7.1) from Methanosarcina barkeri (see paper)
    44% identity, 91% coverage of query (80.9 bits)

porD / Q56316 pyruvate:ferredoxin oxidoreductase δ subunit (EC 1.2.7.1) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 7 papers)
Q56316 pyruvate synthase (subunit 1/4) (EC 1.2.7.1) from Thermotoga maritima (see 2 papers)
    41% identity, 86% coverage of query (80.9 bits)

Q51803 pyruvate synthase (subunit 2/4) (EC 1.2.7.1) from Pyrococcus furiosus (see 2 papers)
    44% identity, 81% coverage of query (70.1 bits)

Q9P9E6 pyruvate synthase (subunit 3/5) (EC 1.2.7.1) from Methanococcus maripaludis (see paper)
    42% identity, 81% coverage of query (68.6 bits)

Q5JIJ8 pyruvate synthase (subunit 3/3) (EC 1.2.7.1) from Thermococcus kodakarensis (see paper)
    44% identity, 83% coverage of query (68.2 bits)

PORD_METTM / P80903 Pyruvate synthase subunit PorD; Pyruvate oxidoreductase delta chain; POR; Pyruvic-ferredoxin oxidoreductase subunit delta from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    40% identity, 79% coverage of query (67.0 bits)

W8CR61 pyruvate synthase (subunit 1/4) (EC 1.2.7.1); pyruvate decarboxylase (subunit 1/4) (EC 4.1.1.1) from Thermococcus guaymasensis (see paper)
    43% identity, 83% coverage of query (66.2 bits)

porD / P56815 pyruvate synthase subunit δ (EC 1.2.7.1) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see 7 papers)
    41% identity, 79% coverage of query (65.5 bits)

Build an alignment

Build an alignment for WP_013259992.1 and 8 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

PNO_CRYPV / Q968X7 Pyruvate dehydrogenase [NADP(+)]; CpPNO; Pyruvate:NADP(+) oxidoreductase; EC 1.2.1.51 from Cryptosporidium parvum (see paper)
    29% identity, 72% coverage of query (51.6 bits)

NDUS8_MOUSE / Q8K3J1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Complex I-23kD; CI-23kD; NADH-ubiquinone oxidoreductase 23 kDa subunit; EC 7.1.1.2 from Mus musculus (Mouse) (see paper)
    34% identity, 80% coverage of query (45.4 bits)

7ak5I / Q8K3J1 Cryo-em structure of respiratory complex i in the deactive state from mus musculus at 3.2 a (see paper)
    34% identity, 80% coverage of query (44.7 bits)

fpoI / Q8PU60 F420H2 dehydrogenase subunit FpoI (EC 1.5.98.3) from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (see 3 papers)
FPOI_METMA / Q8PU60 F(420)H(2) dehydrogenase subunit I; F(420)H(2)-dependent phenazine dehydrogenase subunit I; F(420)H(2)-dependent phenazine oxidoreductase subunit I; FPO subunit I; Methanophenazine hydrogenase subunit I; Methanosarcina-phenazine hydrogenase subunit I; EC 1.5.98.3 from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) (see paper)
Q8PU60 Methanosarcina-phenazine hydrogenase (subunit 7/13) (EC 1.12.98.3) from Methanosarcina mazei (see paper)
    34% identity, 75% coverage of query (43.9 bits)

NDUS8_BOVIN / P42028 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Complex I-23kD; CI-23kD; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY subunit; EC 7.1.1.2 from Bos taurus (Bovine) (see 3 papers)
TC 3.D.1.6.1 / P42028 TYKY (23) (NuoI), component of The vertebrate H+-translocating NADH dehydrogenase (NDH) complex (45 subunits) from Bos taurus (Bovine) (see paper)
    34% identity, 79% coverage of query (43.9 bits)

8ugh1I NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
    34% identity, 79% coverage of query (43.9 bits)

5gupH structure of mammalian respiratory supercomplex I1III2IV1
    34% identity, 79% coverage of query (43.9 bits)

TC 3.D.9.1.1 / Q9P9F8 FpoI, component of F420H2 dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F420:phenazine oxidoreductase) from Methanosarcina mazei (Methanosarcina frisia) (see paper)
    34% identity, 75% coverage of query (43.5 bits)

8b9zI / Q9VF27 Drosophila melanogaster complex i in the active state (dm1) (see paper)
    33% identity, 75% coverage of query (40.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory