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Searching for up to 100 curated homologs for WP_013418715.1 NCBI__GCF_000166055.1:WP_013418715.1 (139 a.a.)

Found high-coverage hits (≥70%) to 8 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q8YH95 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) from Brucella melitensis bv. 1 (see paper)
    63% identity, 93% coverage of query (155 bits)

HSERO_RS20310 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) from Herbaspirillum seropedicae SmR1
    49% identity, 81% coverage of query (111 bits)

hisI / CAX46381.1 phosphoribosyl AMP-cyclohydrolase, partial from Chromohalobacter salexigens (see paper)
    52% identity, 74% coverage of query (93.6 bits)

HIS3_METVA / Q50837 Phosphoribosyl-AMP cyclohydrolase; PRA-CH; EC 3.5.4.19 from Methanococcus vannielii (see paper)
Q50837 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) from Methanococcus vannielii (see paper)
    46% identity, 71% coverage of query (90.5 bits)

At-IE / O82768 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19; EC 3.6.1.31) from Arabidopsis thaliana (see paper)
HIS2_ARATH / O82768 Histidine biosynthesis bifunctional protein hisIE, chloroplastic; Protein HISTIDINE BIOSYNTHESIS 2; EC 3.5.4.19; EC 3.6.1.31 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    42% identity, 71% coverage of query (86.7 bits)

7bgnA Crystal structure of mthisn2-amp complex, a bifunctional enzyme from the histidine biosynthetic pathway
    43% identity, 71% coverage of query (85.5 bits)

7bgmA / A0A072U2X9 Crystal structure of mthisn2, a bifunctional enzyme from the histidine biosynthetic pathway (see paper)
    43% identity, 71% coverage of query (85.1 bits)

HIS2_YEAST / P00815 Histidine biosynthesis trifunctional protein; EC 3.5.4.19; EC 3.6.1.31; EC 1.1.1.23 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    34% identity, 72% coverage of query (58.5 bits)

Build an alignment

Build an alignment for WP_013418715.1 and 8 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory