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Searching for up to 100 curated homologs for WP_013420621.1 NCBI__GCF_000166055.1:WP_013420621.1 (366 a.a.)

Found high-coverage hits (≥70%) to 87 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AZOBR_RS20485 histidinol-phosphate aminotransferase [EC:2.6.1.9] from Azospirillum brasilense Sp245
    54% identity, 98% coverage of query (379 bits)

PGA1_c25240 histidinol-phosphate aminotransferase [EC:2.6.1.9] from Phaeobacter inhibens BS107
    49% identity, 98% coverage of query (333 bits)

HIS8_ZYMMO / P34037 Histidinol-phosphate aminotransferase; Imidazole acetol phosphate aminotransferase; IAP aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
    47% identity, 98% coverage of query (312 bits)

hisH / AAC41445.1 imidazole acetol phosphate aminotransferase from Zymomonas mobilis (see paper)
    47% identity, 98% coverage of query (305 bits)

BPHYT_RS14905 Aromatic-amino-acid transaminase (EC 2.6.1.57) from Burkholderia phytofirmans PsJN
    40% identity, 96% coverage of query (231 bits)

hisC / P17731 histidinol-phosphate aminotransferase; tyrosine/phenylalanine aminotransferase (promiscuous) (EC 2.6.1.1; EC 2.6.1.9) from Bacillus subtilis (strain 168) (see 4 papers)
    36% identity, 95% coverage of query (194 bits)

4r2nA / P9WML5 Crystal structure of rv3772 in complex with its substrate (see paper)
    34% identity, 93% coverage of query (167 bits)

4r5zA Crystal structure of rv3772 encoded aminotransferase
    34% identity, 93% coverage of query (167 bits)

DVU1029 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Desulfovibrio vulgaris Hildenborough JW710
    32% identity, 96% coverage of query (164 bits)

DvMF_0908 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Desulfovibrio vulgaris Miyazaki F
    34% identity, 96% coverage of query (159 bits)

HP15_2427 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Marinobacter adhaerens HP15
    33% identity, 94% coverage of query (150 bits)

PP_0967 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Pseudomonas putida KT2440
    31% identity, 94% coverage of query (143 bits)

Psest_3297 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Pseudomonas stutzeri RCH2
    34% identity, 94% coverage of query (142 bits)

orf2651 / A0A0D3RBW0 tryptophan—pyruvate aminotransferase (EC 2.6.1.99) from Streptomyces griseus (see 2 papers)
    31% identity, 98% coverage of query (138 bits)

HIS8_NICPL / Q9FEW2 Histidinol-phosphate aminotransferase, chloroplastic; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco) (see paper)
    30% identity, 97% coverage of query (137 bits)

Build an alignment

Build an alignment for WP_013420621.1 and 15 homologs with ≥ 30% identity

Select sequences

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Change minimum %identity:

Additional hits (identity < 30%)

BT0202 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Bacteroides thetaiotaomicron VPI-5482
    29% identity, 97% coverage of query (137 bits)

HIS8_TOBAC / O82030 Histidinol-phosphate aminotransferase, chloroplastic; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Nicotiana tabacum (Common tobacco) (see paper)
O82030 histidinol-phosphate transaminase (EC 2.6.1.9) from Nicotiana tabacum (see paper)
    30% identity, 97% coverage of query (135 bits)

HIS8_CALS4 / Q8R5Q4 Histidinol-phosphate aminotransferase; Histidine transaminase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9; EC 2.6.1.38 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
Q8R5Q4 histidine transaminase (EC 2.6.1.38) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
    31% identity, 90% coverage of query (134 bits)

HIS6A_ARATH / B9DHD3 Histidinol-phosphate aminotransferase 1, chloroplastic; Gene duplicate 1-B protein; Imidazole acetol-phosphate transaminase; Protein EMBRYO DEFECTIVE 2196; Protein HISTIDINE BIOSYNTHESIS 6A; EC 2.6.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    29% identity, 91% coverage of query (132 bits)

8bj3A / A0A072U7F9 Crystal structure of medicago truncatula histidinol-phosphate aminotransferase (hisn6) in complex with histidinol-phosphate (see paper)
    28% identity, 91% coverage of query (130 bits)

Pf6N2E2_3251 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Pseudomonas fluorescens FW300-N2E2
    30% identity, 95% coverage of query (129 bits)

4wbtA / Q92R63 Crystal structure of histidinol-phosphate aminotransferase from sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
    30% identity, 90% coverage of query (127 bits)

4r8dA / P9WML7 Crystal structure of rv1600 encoded aminotransferase in complex with plp-mes from mycobacterium tuberculosis
    31% identity, 93% coverage of query (118 bits)

P9WML7 histidinol-phosphate transaminase (EC 2.6.1.9) from Mycobacterium tuberculosis (see 3 papers)
    31% identity, 93% coverage of query (118 bits)

3cq5B / Q9KJU4 Histidinol-phosphate aminotransferase from corynebacterium glutamicum in complex with pmp (see paper)
    30% identity, 95% coverage of query (116 bits)

HIS8_THEMA / Q9X0D0 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    30% identity, 90% coverage of query (116 bits)

2f8jA / Q9X0D0 Crystal structure of histidinol-phosphate aminotransferase (ec 2.6.1.9) (imidazole acetol-phosphate transferase) (tm1040) from thermotoga maritima at 2.40 a resolution
    30% identity, 90% coverage of query (116 bits)

3cq6A Histidinol-phosphate aminotransferase from corynebacterium glutamicum holo-form (plp covalently bound )
    30% identity, 95% coverage of query (116 bits)

1uu1A Complex of histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form)
    30% identity, 90% coverage of query (116 bits)

1h1cA Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima
    30% identity, 90% coverage of query (116 bits)

1uu0A Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form)
    30% identity, 90% coverage of query (116 bits)

MmCobD / Q8PVB1 MmCobD (EC 4.1.1.81; EC 2.7.1.177) from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (see 2 papers)
Q8PVB1 threonine-phosphate decarboxylase (EC 4.1.1.81) from Methanosarcina mazei (see paper)
    28% identity, 91% coverage of query (111 bits)

his3 / GI|1174375 histidinol-phosphate aminotransferase imidazole acetol phosphate transaminase His3; EC 2.6.1.9 from Schizosaccharomyces pombe (see 2 papers)
    26% identity, 96% coverage of query (108 bits)

C1437_CAMJE / Q0P8H7 Dihydroxyacetone phosphate transaminase Cj1437c; Capsule polysaccharide biosynthesis protein Cj1437c; PLP-dependent transaminase Cj1437; EC 2.6.1.- from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
    25% identity, 97% coverage of query (107 bits)

7szpA / A6TBC4 Crystal structure of histidinol-phosphate aminotransferase from klebsiella pneumoniae subsp. Pneumoniae (strain hs11286)
    29% identity, 96% coverage of query (107 bits)

1fg3A / P06986 Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
    28% identity, 96% coverage of query (104 bits)

HisC / b2021 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
hisC / P06986 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Escherichia coli (strain K12) (see 5 papers)
HIS8_ECOLI / P06986 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; HPAT; HspAT; EC 2.6.1.9 from Escherichia coli (strain K12) (see 3 papers)
    28% identity, 96% coverage of query (104 bits)

3ly1D / Q6D4Z0 Crystal structure of putative histidinol-phosphate aminotransferase (yp_050345.1) from erwinia carotovora atroseptica scri1043 at 1.80 a resolution
    27% identity, 91% coverage of query (104 bits)

1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate
    28% identity, 96% coverage of query (104 bits)

1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate
    28% identity, 86% coverage of query (98.6 bits)

ptaA / Q9I0V2 pyoverdine aminotransferase from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
    26% identity, 94% coverage of query (95.1 bits)

BAD06364.1 aminotransferase from Thermus thermophilus (see paper)
    27% identity, 81% coverage of query (90.1 bits)

1v2eA / Q75WK2 Crystal structure of t.Th hb8 glutamine aminotransferase complex with a-keto-g-methylthiobutyrate (see paper)
    27% identity, 81% coverage of query (90.1 bits)

1v2fA Crystal structure of t.Th hb8 glutamine aminotransferase complex with 3-phenylpropionate
    27% identity, 81% coverage of query (90.1 bits)

CAA67877.1 aspartate aminotransferase from Thermus aquaticus (see paper)
    29% identity, 78% coverage of query (87.0 bits)

1gd9A / O59096 Crystall structure of pyrococcus protein-a1 (see paper)
    26% identity, 85% coverage of query (86.7 bits)

1gdeA Crystal structure of pyrococcus protein a-1 e-form
    26% identity, 85% coverage of query (86.7 bits)

O59096 aromatic-amino-acid transaminase (EC 2.6.1.57) from Pyrococcus horikoshii (see paper)
    26% identity, 85% coverage of query (86.3 bits)

1o4sB / Q9X0Y2 Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
    25% identity, 86% coverage of query (86.3 bits)

AAT_THEMA / Q9X0Y2 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    25% identity, 86% coverage of query (85.9 bits)

AAPAT_THET8 / Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 5 papers)
Q56232 aspartate-prephenate aminotransferase (EC 2.6.1.78) from Thermus thermophilus (see paper)
aspC / RF|YP_143312.1 aspartate transaminase; EC 2.6.1.1 from Thermus thermophilus HB8 (see 2 papers)
    26% identity, 78% coverage of query (82.0 bits)

ARAT2_THELN / H3ZPU1 Aromatic-amino-acid aminotransferase 2; ARAT-II; AROAT; EC 2.6.1.57 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
    24% identity, 82% coverage of query (82.0 bits)

1b5oA / Q56232 Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
    26% identity, 78% coverage of query (82.0 bits)

1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate
    26% identity, 78% coverage of query (82.0 bits)

1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan
    26% identity, 78% coverage of query (82.0 bits)

1bkgA Aspartate aminotransferase from thermus thermophilus with maleate
    26% identity, 78% coverage of query (82.0 bits)

1bjwA Aspartate aminotransferase from thermus thermophilus
    26% identity, 78% coverage of query (82.0 bits)

PP_3721 arginine:pyruvate transaminase AruH (EC 2.6.1.84) from Pseudomonas putida KT2440
    25% identity, 89% coverage of query (81.3 bits)

A0A6F8T0V6 aspartate transaminase (EC 2.6.1.1) from Geobacillus sp. MAS1 (see paper)
    26% identity, 79% coverage of query (79.7 bits)

Q8TQ40 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Methanosarcina acetivorans (see paper)
    28% identity, 75% coverage of query (79.3 bits)

8wkjA / A0A130QXX8 The crystal structure of aspartate aminotransferases lpg0070 from legionella pneumophila (see paper)
    26% identity, 73% coverage of query (79.0 bits)

1j32A / Q8RR70 Aspartate aminotransferase from phormidium lapideum
aspC / BAB86290.1 aspartate aminotransferase from Phormidium lapideum (see paper)
    26% identity, 94% coverage of query (78.6 bits)

aspC / GB|CAA63799.1 aspartate transaminase; EC 2.6.1.1 from Geobacillus stearothermophilus (see paper)
    25% identity, 86% coverage of query (77.8 bits)

AAPAT_NITEU / Q82WA8 Aspartate/prephenate aminotransferase; AspAT / PAT; EC 2.6.1.1; EC 2.6.1.79 from Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) (see paper)
    27% identity, 72% coverage of query (77.4 bits)

4m2mA Crystal structure of plp-dependent cyclase orfr in complex with plp-l- arg
    28% identity, 81% coverage of query (76.6 bits)

4m2jA / G9MBV4 Crystal structure of plp-dependent cyclase orfr in complex with au (see paper)
    28% identity, 81% coverage of query (76.3 bits)

aspB / GB|CAB14153.1 aspartate transaminase; EC 2.6.1.1 from Bacillus subtilis (see paper)
aspB / AAB38454.1 aspartate aminotransferase from Bacillus subtilis (see paper)
    23% identity, 86% coverage of query (75.9 bits)

aruH / Q9HUI9 L-arginine:pyruvate transaminase subunit (EC 2.6.1.84) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
ARUH_PSEAE / Q9HUI9 Arginine--pyruvate transaminase AruH; EC 2.6.1.84 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
Q9HUI9 arginine-pyruvate transaminase (EC 2.6.1.84) from Pseudomonas aeruginosa (see paper)
    25% identity, 73% coverage of query (75.5 bits)

mfnC / Q58097 2-furaldehyde phosphate aminotransferase (EC 2.6.1.108) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
MFNC_METJA / Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase; 4-HFC-P:alanine aminotransferase; EC 2.6.1.108 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase (EC 2.6.1.108) from Methanocaldococcus jannaschii (see paper)
    24% identity, 80% coverage of query (75.5 bits)

5yhvB Crystal structure of an aminotransferase from mycobacterium tuberculosis
    26% identity, 78% coverage of query (72.4 bits)

5yhvA / P96847 Crystal structure of an aminotransferase from mycobacterium tuberculosis
    26% identity, 78% coverage of query (72.0 bits)

AVTA_MYCTU / P96847 Valine--pyruvate aminotransferase; Alanine--valine transaminase; EC 2.6.1.66 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    26% identity, 78% coverage of query (72.0 bits)

5wmhA Arabidopsis thaliana prephenate aminotransferase
    25% identity, 73% coverage of query (63.9 bits)

5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v
    25% identity, 73% coverage of query (63.9 bits)

6l1oB Product bound bacf structure from bacillus subtillis
    26% identity, 84% coverage of query (62.4 bits)

6l1lB / P39643 Apo-bacf structure from bacillus subtillis (see paper)
    26% identity, 84% coverage of query (62.4 bits)

6l1nA Substrate bound bacf structure from bacillus subtillis
    26% identity, 84% coverage of query (62.4 bits)

5wmlA / Q9SIE1 Arabidopsis thaliana prephenate aminotransferase mutant- k306a (see paper)
    25% identity, 73% coverage of query (61.6 bits)

DAPAT_CHLTR / O84395 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Chlamydia trachomatis serovar D (strain ATCC VR-885 / DSM 19411 / UW-3/Cx) (see 2 papers)
O84395 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Chlamydia trachomatis (see 2 papers)
    24% identity, 73% coverage of query (57.4 bits)

1w7nA Crystal structure of human kynurenine aminotransferase i in pmp form
    24% identity, 86% coverage of query (55.5 bits)

1w7mA Crystal structure of human kynurenine aminotransferase i in complex with l-phe
    24% identity, 86% coverage of query (55.5 bits)

1w7lA Crystal structure of human kynurenine aminotransferase i
    24% identity, 86% coverage of query (55.5 bits)

6f35A / P58350 Crystal structure of the aspartate aminotranferase from rhizobium meliloti (see paper)
    24% identity, 92% coverage of query (55.5 bits)

SMc04386 2-aminoadipate:2-oxoglutarate aminotransferase (EC 2.6.1.39) from Sinorhizobium meliloti 1021
AAT_RHIME / P58350 Aspartate aminotransferase; AAT; AspAT; Putative 2-aminoadipate transaminase; Transaminase A; EC 2.6.1.1; EC 2.6.1.39 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see 2 papers)
    24% identity, 92% coverage of query (54.3 bits)

ISS1 / Q9C969 aromatic aminotransferase ISS1 (EC 2.6.1.27) from Arabidopsis thaliana (see paper)
ISS1_ARATH / Q9C969 Aromatic aminotransferase ISS1; Methionine aminotransferase ISS1; Phenylalanine aminotransferase ISS1; Protein INDOLE SEVERE SENSITIVE 1; Protein REVERSAL OF SAV3 PHENOTYPE 1; Tryptophan aminotransferase ISS1; Tyrosine aminotransferase ISS1; EC 2.6.1.27; EC 2.6.1.5; EC 2.6.1.88 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9C969 aromatic-amino-acid transaminase (EC 2.6.1.57) from Arabidopsis thaliana (see paper)
    25% identity, 83% coverage of query (52.0 bits)

2x5dD / Q9HV83 Crystal structure of a probable aminotransferase from pseudomonas aeruginosa (see paper)
    26% identity, 73% coverage of query (50.8 bits)

3jtxB Crystal structure of aminotransferase (np_283882.1) from neisseria meningitidis z2491 at 1.91 a resolution
    25% identity, 73% coverage of query (47.0 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory