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Searching for up to 100 curated homologs for WP_013429643.1 NCBI__GCF_000166775.1:WP_013429643.1 (772 a.a.)

Found high-coverage hits (≥70%) to 55 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

2f2hA / P31434 Structure of the yici thiosugar michaelis complex (see paper)
    53% identity, 99% coverage of query (875 bits)

YicI / b3656 α-D-xyloside xylohydrolase (EC 3.2.1.177) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
yicI / P31434 α-D-xyloside xylohydrolase (EC 3.2.1.177) from Escherichia coli (strain K12) (see 9 papers)
XYLS_ECOLI / P31434 Alpha-xylosidase; EC 3.2.1.177 from Escherichia coli (strain K12) (see 3 papers)
P31434 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from Escherichia coli (see 3 papers)
AAC76680.1 α-xylosidase (YicI;EcYicI;b3656) (EC 3.2.1.177) (see protein)
BAE77637.1 α-xylosidase (YicI) (EC 3.2.1.177) (see protein)
yicI / RF|NP_418113 alpha-xylosidase; EC 3.2.1.- from Escherichia coli K12 (see 7 papers)
    53% identity, 99% coverage of query (875 bits)

1xskA Structure of a family 31 alpha glycosidase glycosyl-enzyme intermediate
    53% identity, 99% coverage of query (875 bits)

AGDD_EMENI / Q5AW25 Alpha-xylosidase; EC 3.2.1.177 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
EAA62085.1 α-xylosidase (AgdD;AN7505) (EC 3.2.1.177) (see protein)
agdD alpha-xylosidase from Emericella nidulans (see paper)
    50% identity, 89% coverage of query (725 bits)

XYLQ_LACPE / P96793 Alpha-xylosidase XylQ; EC 3.2.1.177 from Lactiplantibacillus pentosus (Lactobacillus pentosus) (see paper)
AAC62251.1 α-xylosidase (XylQ) (EC 3.2.1.177) (see protein)
    46% identity, 97% coverage of query (668 bits)

AAO75446.1 α-glucosidase (BT0339;BT_0339) (EC 3.2.1.20) (see protein)
    37% identity, 72% coverage of query (368 bits)

BAQ19546.1 α-glucosidase (AG31A;BspAG31A) (EC 3.2.1.20) (see protein)
    31% identity, 70% coverage of query (271 bits)

Build an alignment

Build an alignment for WP_013429643.1 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q9F234 alpha-glucosidase (EC 3.2.1.20) from Bacillus thermoamyloliquefaciens (see paper)
BAA76396.1 α-glucosidase II / oligo-α-1,6-glucosidase (BthG II) (EC 3.2.1.10|3.2.1.20) (see protein)
    27% identity, 84% coverage of query (260 bits)

5hxmA / Q8Y4J2 Cycloalternan-forming enzyme from listeria monocytogenes in complex with panose (see paper)
    26% identity, 87% coverage of query (239 bits)

4kwuA 1.9 angstrom resolution crystal structure of uncharacterized protein lmo2446 from listeria monocytogenes egd-e in complex with alpha-d- glucose, beta-d-glucose, magnesium and calcium
    26% identity, 87% coverage of query (239 bits)

ABR26230.1 α-glucosidase (EC 3.2.1.20) (see protein)
    29% identity, 74% coverage of query (236 bits)

Q9HLD0 alpha-glucosidase (EC 3.2.1.20) from Thermoplasma acidophilum (see paper)
CAC11443.1 α-glucosidase (AglA;Ta0298) (EC 3.2.1.20) (see protein)
    28% identity, 74% coverage of query (226 bits)

OL4AG_CELJU / B3PEE6 Oligosaccharide 4-alpha-D-glucosyltransferase; Alpha-glucosidase 31B; CJAgd31B; EC 2.4.1.161 from Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) (see paper)
ACE84782.1 oligosaccharide α-1,4-transglucosylase 31B (CjAgd31B;CJA_3248) (Agd31B) (EC 2.4.1.161) (see protein)
    27% identity, 79% coverage of query (225 bits)

BAD34979.1 3-α-isomaltosyltransferase (CtsY;IMT) (EC 2.4.1.-) (see protein)
    27% identity, 80% coverage of query (223 bits)

5i24A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf021
    26% identity, 79% coverage of query (223 bits)

5i23A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf022
    26% identity, 79% coverage of query (223 bits)

4ba0A / B3PEE6 Crystal structure of agd31b, alpha-transglucosylase, complexed with 5f-alpha-glcf (see paper)
    26% identity, 79% coverage of query (222 bits)

8rw3A Crystal structure of agd31b, alpha-transglucosylase, complexed with a non-covalent 1,2- cyclophellitol aziridine
    26% identity, 79% coverage of query (222 bits)

7p4dAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    27% identity, 72% coverage of query (221 bits)

7p4cAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    27% identity, 72% coverage of query (221 bits)

5npeA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with beta cyclophellitol aziridine probe ky358
    27% identity, 72% coverage of query (221 bits)

5npbA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol cyclosulfate probe me647
    27% identity, 72% coverage of query (221 bits)

4b9zA Crystal structure of agd31b, alpha-transglucosylase, complexed with acarbose
    27% identity, 72% coverage of query (221 bits)

4b9yA Crystal structure of apo agd31b, alpha-transglucosylase in glycoside hydrolase family 31
    27% identity, 72% coverage of query (221 bits)

5npdA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol aziridine probe cf021
    27% identity, 72% coverage of query (219 bits)

5npcA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with unreacted alpha cyclophellitol cyclosulfate probe me647
    27% identity, 72% coverage of query (219 bits)

xylS / Q9P999 α-D-xyloside xylohydrolase (EC 3.2.1.177) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 2 papers)
XYLS_SACS2 / Q9P999 Alpha-xylosidase; EC 3.2.1.177 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q9P999 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from Saccharolobus solfataricus (see 2 papers)
CAB99206.1 α-xylosidase (XylS;SS03022) (EC 3.2.1.177) (see protein)
    28% identity, 71% coverage of query (214 bits)

P0CD66 alpha-glucosidase (EC 3.2.1.20) from Saccharolobus solfataricus (see 3 papers)
AAC38215.1 α-glucosidase with α-mannosidase activity (MalA;SsMalA;Sso1_0793) (EC 3.2.1.20|3.2.1.24) (see protein)
AAK43151.1 α-glucosidase (MalA;SSO3051) (EC 3.2.1.20) (see protein)
    27% identity, 71% coverage of query (202 bits)

AGLU_SACS9 / D0KQM8 Alpha-glucosidase; Maltase; EC 3.2.1.20 from Saccharolobus solfataricus (strain 98/2) (Sulfolobus solfataricus) (see paper)
D0KQM8 alpha-glucosidase (EC 3.2.1.20) from Saccharolobus solfataricus (see paper)
    28% identity, 71% coverage of query (202 bits)

O24375 mannosyl-oligosaccharide alpha-1,3-glucosidase (EC 3.2.1.207) from Solanum tuberosum (see paper)
CAA04707.1 α-glucosidase (Mal1) (EC 3.2.1.20) (see protein)
CAA04707.1 alpha-glucosidase from Solanum tuberosum (see paper)
    26% identity, 79% coverage of query (187 bits)

A0A169PW02 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from uncultured microorganism (see paper)
    26% identity, 74% coverage of query (185 bits)

5zn7A Crystal structure of gh31 alpha-xylosidase from a soil metagenome complexed with xylose
    26% identity, 74% coverage of query (185 bits)

7jtyA Co-crystal structure of alpha glucosidase with compound 1
    25% identity, 75% coverage of query (177 bits)

7kb6A Co-crystal structure of alpha glucosidase with compound 7
    25% identity, 74% coverage of query (176 bits)

7k9tA Co-crystal structure of alpha glucosidase with compound 5
    25% identity, 74% coverage of query (176 bits)

5f7sA Cycloalternan-degrading enzyme from trueperella pyogenes
    24% identity, 83% coverage of query (175 bits)

EDO10789.1 α-xylosidase (BoGH31;BACOVA_03422) (EC 3.2.1.177) (see protein)
    23% identity, 87% coverage of query (172 bits)

7wj9A / A2RM80 Crystal structure of lactococcus lactis subsp. Cremoris gh31 alpha-1, 3-glucosidase, p21 space group (see paper)
    24% identity, 73% coverage of query (162 bits)

B5THE3 sucrose alpha-glucosidase (EC 3.2.1.48) from Mus musculus (see paper)
    24% identity, 74% coverage of query (162 bits)

7wjbA Crystal structure of lactococcus lactis subsp. Cremoris gh31 alpha-1, 3-glucosidase in complex with glucose
    24% identity, 73% coverage of query (162 bits)

BAN67474.1 α-glucosidase (HdAgl1;HdAgl) (EC 3.2.1.20) (see protein)
    23% identity, 80% coverage of query (160 bits)

5nn8A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with acarbose
    22% identity, 80% coverage of query (158 bits)

5nn5A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with 1-deoxynojirimycin
    22% identity, 80% coverage of query (157 bits)

7p2zAaA Lysosomal alpha-glucosidase
    22% identity, 80% coverage of query (157 bits)

8cb6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in covalent complex with tamra tagged 1,6-epi-cylcophellitol aziridine activity based probe
    22% identity, 80% coverage of query (157 bits)

5kzwA / P10253 Crystal structure of human gaa
    22% identity, 80% coverage of query (156 bits)

8cb1A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-pnt-dnm 15
    22% identity, 80% coverage of query (156 bits)

7p32AAA Lysosomal alpha-glucosidase
    22% identity, 80% coverage of query (156 bits)

5nn4A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-acetyl-cysteine
    22% identity, 80% coverage of query (156 bits)

5nn6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-hydroxyethyl-1-deoxynojirimycin
    22% identity, 80% coverage of query (156 bits)

ACH86011.1 membrane-bound maltase-glucoamylase (MGAM) (EC 3.2.1.20) (see protein)
    22% identity, 81% coverage of query (142 bits)

BAC54958.1 6-α-glucosyltransferase (CtsZ;6GT) (EC 2.4.1.-) (see protein)
    25% identity, 80% coverage of query (142 bits)

SUIS_HUMAN / P14410 Sucrase-isomaltase, intestinal; EC 3.2.1.48; EC 3.2.1.10 from Homo sapiens (Human) (see 7 papers)
P14410 oligo-1,6-glucosidase (EC 3.2.1.10); sucrose alpha-glucosidase (EC 3.2.1.48) from Homo sapiens (see 6 papers)
    24% identity, 70% coverage of query (140 bits)

3lppB / P14410 Crystal complex of n-terminal sucrase-isomaltase with kotalanol (see paper)
    23% identity, 82% coverage of query (140 bits)

AAT18166.1 sucrase-isomaltase (SI) (EC 3.2.1.10|3.2.1.48) (see protein)
    24% identity, 70% coverage of query (140 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory