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Searching for up to 100 curated homologs for WP_013444375.1 NCBI__GCF_000183135.1:WP_013444375.1 (582 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

pgcA / P18159 α-phosphoglucomutase (EC 5.4.2.2) from Bacillus subtilis (strain 168) (see paper)
PGCA_BACSU / P18159 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
    46% identity, 90% coverage of query (469 bits)

pgmA / CAB96418.1 phosphoglucomutase from Streptococcus thermophilus (see paper)
    41% identity, 96% coverage of query (414 bits)

PGCA_STAA8 / Q2FVC1 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    38% identity, 90% coverage of query (335 bits)

PGM2 / Q96G03 phosphoglucomutase-2 (EC 5.4.2.2; EC 5.4.2.7) from Homo sapiens (see 2 papers)
PGM2_HUMAN / Q96G03 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-2; EC 5.4.2.7; EC 5.4.2.2 from Homo sapiens (Human) (see 2 papers)
    35% identity, 92% coverage of query (333 bits)

PGM2_MOUSE / Q7TSV4 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-1; Phosphoglucomutase-2; PGM 2; EC 5.4.2.7; EC 5.4.2.2 from Mus musculus (Mouse) (see paper)
    33% identity, 92% coverage of query (319 bits)

PGM3_SCHPO / O74478 Probable phosphoribomutase; PRM; Phosphoglucomutase 3 homolog; PGM 3 homolog; EC 5.4.2.7 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    32% identity, 92% coverage of query (306 bits)

PGM2L_MOUSE / Q8CAA7 Glucose 1,6-bisphosphate synthase; Phosphoglucomutase-2-like 1; EC 2.7.1.106 from Mus musculus (Mouse) (see paper)
    34% identity, 96% coverage of query (300 bits)

PGM2L_HUMAN / Q6PCE3 Glucose 1,6-bisphosphate synthase; PMMLP; Phosphoglucomutase-2-like 1; EC 2.7.1.106 from Homo sapiens (Human) (see 3 papers)
    33% identity, 96% coverage of query (296 bits)

C6L2F4 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Toxoplasma gondii (see paper)
    32% identity, 97% coverage of query (277 bits)

PGM3_YEAST / Q03262 Phosphoribomutase; PRM; Phosphoglucomutase 3; PGM 3; EC 5.4.2.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
    32% identity, 94% coverage of query (275 bits)

Build an alignment

Build an alignment for WP_013444375.1 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PGMMM_THEKO / Q68BJ6 Phosphoglucomutase/phosphomannomutase; PGM/PMM; EC 5.4.2.2; EC 5.4.2.8 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    27% identity, 87% coverage of query (106 bits)

PH0923 / O58651 phosphomannose mutase (EC 5.4.2.8) from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
1wqaA / O58651 Crystal structure of pyrococcus horikoshii phosphomannomutase/phosphoglucomutase complexed with mg2+
    26% identity, 86% coverage of query (99.0 bits)

Q980S1 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2); phosphomannomutase (EC 5.4.2.8) from Saccharolobus solfataricus (see paper)
    22% identity, 86% coverage of query (86.7 bits)

PPM_THEKO / Q6I7B6 Phosphopentomutase; PPM; EC 5.4.2.7 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
Q6I7B6 phosphopentomutase (EC 5.4.2.7) from Thermococcus kodakarensis (see paper)
    25% identity, 86% coverage of query (80.9 bits)

Q81VN7 phosphoglucosamine mutase (EC 5.4.2.10) from Bacillus anthracis (see paper)
    23% identity, 91% coverage of query (78.2 bits)

A0A0H3NJ17 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
Q8ZQW9 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    24% identity, 86% coverage of query (74.3 bits)

2fuvA / Q8ZQW9 Phosphoglucomutase from salmonella typhimurium.
    24% identity, 86% coverage of query (74.3 bits)

P74027 glucose-1,6-bisphosphate synthase from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
    23% identity, 78% coverage of query (72.4 bits)

Q5X1A3 phosphoglucosamine mutase (EC 5.4.2.10) from Legionella pneumophila (see paper)
    23% identity, 86% coverage of query (70.9 bits)

PGM_DROME / Q9VUY9 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Drosophila melanogaster (Fruit fly) (see paper)
    24% identity, 87% coverage of query (68.9 bits)

6nqhA Xanthomonas citri dephospho-pgm in complex with xylose-1-phosphate
    24% identity, 81% coverage of query (67.4 bits)

6np8A Xanthomonas citri phospho-pgm in complex with mannose-6-phosphate
    24% identity, 81% coverage of query (67.4 bits)

6nolA Xanthomonas citri dephospho-pgm in complex with mannose-1-phosphate
    24% identity, 81% coverage of query (67.4 bits)

6nnpA Xanthomonas citri dephospho-pgm in complex with glucose-6-phosphate
    24% identity, 81% coverage of query (67.4 bits)

6nn2A Xanthomonas citri pgm apo-phospho
    24% identity, 81% coverage of query (67.4 bits)

6n1eA Crystal structure of x. Citri phosphoglucomutase in complex with 1- methyl-glucose 6-phosphate
    24% identity, 81% coverage of query (67.4 bits)

6mnvA Crystal structure of x. Citri phosphoglucomutase in complex with ch2fg1p
    24% identity, 81% coverage of query (67.4 bits)

6mlhA Crystal structure of x. Citri phosphoglucomutase in complex with glucopyranosyl-1-methyl-phosphonic acid
    24% identity, 81% coverage of query (67.4 bits)

6mlfA Crystal structure of x. Citri phosphoglucomutase in complex with 6- fluoro glucose 1-phosphate
    24% identity, 81% coverage of query (67.4 bits)

5kl0A Crystal structure of phosphoglucomutase from xanthomonas citri citri complexed with glucose-1,6-biphosphate
    24% identity, 81% coverage of query (67.4 bits)

6mlwA Crystal structure of x. Citri phosphoglucomutase in complex with 2- fluoro mannosyl-1-methyl-phosphonic acid
    24% identity, 81% coverage of query (67.0 bits)

5bmpA Crystal structure of phosphoglucomutase from xanthomonas citri complexed with glucose-1-phosphate (see paper)
    24% identity, 81% coverage of query (67.0 bits)

7p5oB / Q4WY53 Crystal structure of aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate
    26% identity, 78% coverage of query (65.1 bits)

7pjcB / A0A1D8PSA9 The structure of candida albicans phosphoglucomutase with isothiazolone modification on cys359
    24% identity, 87% coverage of query (61.6 bits)

PGM1 / P36871 phosphoglucomutase-1 (EC 5.4.2.2) from Homo sapiens (see 3 papers)
PGM1_HUMAN / P36871 Phosphoglucomutase-1; PGM 1; Glucose phosphomutase 1; EC 5.4.2.2 from Homo sapiens (Human) (see 8 papers)
P36871 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Homo sapiens (see 4 papers)
    24% identity, 87% coverage of query (57.0 bits)

5jn5A Crystal structure of the d263y missense variant of human pgm1
    24% identity, 87% coverage of query (55.5 bits)

PGM_SCHPO / O74374 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    23% identity, 74% coverage of query (51.6 bits)

7s0wB / P36871 Crystal structure of the t337m variant of human pgm-1 (see paper)
    23% identity, 70% coverage of query (46.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory