Sites on a Tree

 

Searching for up to 100 curated homologs for WP_013555012.1 NCBI__GCF_000186245.1:WP_013555012.1 (758 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

glnS / P56926 glutaminyl-tRNA synthetase (EC 6.1.1.18) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
    44% identity, 97% coverage of query (668 bits)

GlnS / b0680 glutamine—tRNA ligase (EC 6.1.1.18) from Escherichia coli K-12 substr. MG1655 (see 49 papers)
glnS / P00962 glutamine—tRNA ligase (EC 6.1.1.18) from Escherichia coli (strain K12) (see 51 papers)
SYQ_ECOLI / P00962 Glutamine--tRNA ligase; Glutaminyl-tRNA synthetase; GlnRS; EC 6.1.1.18 from Escherichia coli (strain K12) (see 5 papers)
P00962 glutamine-tRNA ligase (EC 6.1.1.18); glutamate-tRNAGln ligase (EC 6.1.1.24) from Escherichia coli (see 6 papers)
glnS glutaminyl-tRNA synthetase; EC 6.1.1.18 from Escherichia coli K12 (see paper)
    56% identity, 71% coverage of query (624 bits)

4jyzA / P00962 Crystal structure of e. Coli glutaminyl-tRNA synthetase bound to atp and native tRNA(gln) containing the cmnm5s2u34 anticodon wobble base (see paper)
    56% identity, 71% coverage of query (618 bits)

1o0cA Crystal structure of l-glutamate and ampcpp bound to glutamine aminoacyl tRNA synthetase
    55% identity, 71% coverage of query (602 bits)

1o0bA Crystal structure of l-glutamine and ampcpp bound to glutamine aminoacyl tRNA synthetase
    55% identity, 71% coverage of query (602 bits)

1gtsA Structural basis for transfer RNA aminoaceylation by escherichia coli glutaminyl-tRNA synthetase
    55% identity, 71% coverage of query (602 bits)

1exdA Crystal structure of a tight-binding glutamine tRNA bound to glutamine aminoacyl tRNA synthetase
    55% identity, 71% coverage of query (602 bits)

1euqA Crystal structure of glutaminyl-tRNA synthetase complexed with a tRNA- gln mutant and an active-site inhibitor
    55% identity, 71% coverage of query (602 bits)

5zdkA / Q5SKU4 Crystal structure analysis of ttqrs in complex with atp (see paper)
    57% identity, 70% coverage of query (597 bits)

2re8A Glutaminyl-tRNA synthetase mutant c229r with bound analog 5'-o-[n-(l- glutamyl)-sulfamoyl]adenosine
    55% identity, 71% coverage of query (597 bits)

A0A125YXL3 glutamine-tRNA ligase (EC 6.1.1.18) from Toxoplasma gondii (see paper)
    49% identity, 74% coverage of query (550 bits)

SYEC_YEAST / P46655 Glutamate--tRNA ligase, cytoplasmic; Glutamyl-tRNA synthetase; (c)ERS; GluRS; P85; EC 6.1.1.17 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P46655 glutamate-tRNA ligase (EC 6.1.1.17) from Saccharomyces cerevisiae (see 3 papers)
    35% identity, 72% coverage of query (304 bits)

SYEC_DICDI / Q54KB8 Probable glutamate--tRNA ligase, cytoplasmic; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Dictyostelium discoideum (Social amoeba) (see paper)
    33% identity, 73% coverage of query (295 bits)

SYEP_CRIGR / Q7SIA2 Bifunctional glutamate/proline--tRNA ligase; Bifunctional aminoacyl-tRNA synthetase; Glutamyl-prolyl-tRNA synthetase; EC 6.1.1.17; EC 6.1.1.15 from Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (see paper)
    32% identity, 77% coverage of query (257 bits)

Build an alignment

Build an alignment for WP_013555012.1 and 14 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory