Searching for up to 100 curated homologs for WP_013706968.1 NCBI__GCF_000195295.1:WP_013706968.1 (441 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

hom / AAF21129.1 homoserine dehydrogenase from Methylobacillus flagellatus (see paper)
    49% identity, 98% coverage of query (395 bits)

DHOM_NEIG1 / Q5F8J4 Homoserine dehydrogenase; HDH; HSD; NAD(+)-dependent homoserine dehydrogenase; NAD(+)-dependent HSD; NgHSD; EC 1.1.1.3 from Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) (see paper)
    46% identity, 93% coverage of query (364 bits)

D8WXQ1 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
    41% identity, 98% coverage of query (352 bits)

DvMF_1412 homoserine dehydrogenase (EC 1.1.1.3) from Desulfovibrio vulgaris Miyazaki F
    43% identity, 98% coverage of query (335 bits)

DHOM_BACSU / P19582 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Bacillus subtilis (strain 168) (see 3 papers)
P19582 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus subtilis (see paper)
    39% identity, 98% coverage of query (314 bits)

6dzsA / K5BJC9 Mycobacterial homoserine dehydrogenase thra in complex with NADP
    43% identity, 98% coverage of query (305 bits)

DHOM_CORGL / P08499 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 2 papers)
P08499 homoserine dehydrogenase (EC 1.1.1.3) from Corynebacterium glutamicum (see 2 papers)
    41% identity, 97% coverage of query (305 bits)

Q56R01 homoserine dehydrogenase (EC 1.1.1.3) from Streptomyces clavuligerus (see paper)
    41% identity, 98% coverage of query (296 bits)

Ga0059261_2711 homoserine dehydrogenase (EC 1.1.1.3) from Sphingomonas koreensis DSMZ 15582
    44% identity, 94% coverage of query (296 bits)

P46806 homoserine dehydrogenase (EC 1.1.1.3) from Mycobacterium leprae (see paper)
    42% identity, 99% coverage of query (291 bits)

A0A0H2WVX4 homoserine dehydrogenase (EC 1.1.1.3) from Staphylococcus aureus (see 2 papers)
    37% identity, 89% coverage of query (270 bits)

DHOM_LACLC / P52985 Homoserine dehydrogenase; HDH; HSD; EC 1.1.1.3 from Lactococcus lactis subsp. cremoris (Streptococcus cremoris) (see paper)
    36% identity, 91% coverage of query (257 bits)

D8WXQ2 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
    42% identity, 72% coverage of query (249 bits)

4pg7A / A0A0M3KKV6 Crystal structure of s. Aureus homoserine dehydrogenase at ph7.5 (see paper)
    36% identity, 89% coverage of query (248 bits)

Q9WZ17 homoserine dehydrogenase (EC 1.1.1.3); aspartate kinase (EC 2.7.2.4) from Thermotoga maritima (see paper)
    35% identity, 89% coverage of query (201 bits)

DHOM_PSECO / P0DXC5 NAD(+)-dependent homoserine dehydrogenase; NAD(+)-dependent HSD; EC 1.1.1.3 from Pseudomonas canavaninivorans (see paper)
    36% identity, 72% coverage of query (166 bits)

Build an alignment

Build an alignment for WP_013706968.1 and 16 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

DHOM_PYRHO / O58802 Homoserine dehydrogenase; HDH; HSD; HseDH; EC 1.1.1.3 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
O58802 homoserine dehydrogenase (EC 1.1.1.3) from Pyrococcus horikoshii (see paper)
4xb1A / O58802 Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH (see paper)
    29% identity, 71% coverage of query (116 bits)

4xb2A Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH
    29% identity, 71% coverage of query (116 bits)

3ingA / Q9HIZ7 Crystal structure of homoserine dehydrogenase (np_394635.1) from thermoplasma acidophilum at 1.95 a resolution
    26% identity, 72% coverage of query (88.2 bits)

Q5AIA2 homoserine dehydrogenase (EC 1.1.1.3) from Candida albicans (see 2 papers)
    25% identity, 73% coverage of query (78.6 bits)

3jsaA / Q97BR6 Homoserine dehydrogenase from thermoplasma volcanium complexed with NAD
    26% identity, 72% coverage of query (75.5 bits)

MetM / b3940 fused aspartate kinase/homoserine dehydrogenase 2 (EC 2.7.2.4; EC 1.1.1.3) from Escherichia coli K-12 substr. MG1655 (see paper)
metL / P00562 fused aspartate kinase/homoserine dehydrogenase 2 (EC 2.7.2.4; EC 1.1.1.3) from Escherichia coli (strain K12) (see 9 papers)
    26% identity, 72% coverage of query (75.1 bits)

AAA16972.1 aspartokinase-homoserine dehydrogenase, partial from Daucus carota (see paper)
    27% identity, 72% coverage of query (74.3 bits)

O63067 homoserine dehydrogenase (EC 1.1.1.3) from Glycine max (see paper)
    25% identity, 72% coverage of query (73.6 bits)

AKH2_ARATH / O81852 Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic; AK-HD 2; AK-HSDH 2; Beta-aspartyl phosphate homoserine 2; EC 2.7.2.4; EC 1.1.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    25% identity, 72% coverage of query (67.4 bits)

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