Searching for up to 100 curated homologs for WP_013835838.1 NCBI__GCF_000214825.1:WP_013835838.1 (416 a.a.)
Found high-coverage hits (≥70%) to 44 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
SerA / b2913 phosphoglycerate dehydrogenase (EC 1.1.1.95; EC 1.1.1.399) from Escherichia coli K-12 substr. MG1655 (see 36 papers)
serA / P0A9T0 phosphoglycerate dehydrogenase (EC 1.1.1.95; EC 1.1.1.399) from Escherichia coli (strain K12) (see 36 papers)
SERA_ECOLI / P0A9T0 D-3-phosphoglycerate dehydrogenase; PGDH; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Escherichia coli (strain K12) (see paper)
C3SVM7 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escherichia coli (see paper)
P0A9T0 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escherichia coli (see 7 papers)
serA / RF|NP_417388 D-3-phosphoglycerate dehydrogenase; EC 1.1.1.95 from Escherichia coli K12 (see 5 papers)
65% identity, 97% coverage of query (526 bits)
1ybaA The active form of phosphoglycerate dehydrogenase
65% identity, 97% coverage of query (525 bits)
2p9eA / P0A9T0 Crystal structure of g336v mutant of e.Coli phosphoglycerate dehydrogenase (see paper)
65% identity, 97% coverage of query (524 bits)
1psdA The allosteric ligand site in the vmax-type cooperative enzyme phosphoglycerate dehydrogenase
65% identity, 97% coverage of query (523 bits)
A4VGK3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pseudomonas stutzeri (see paper)
62% identity, 97% coverage of query (513 bits)
Q9I6H5 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pseudomonas aeruginosa (see paper)
62% identity, 97% coverage of query (511 bits)
1sc6D / P0A9T0 Crystal structure of w139g d-3-phosphoglycerate dehydrogenase complexed with NAD+ (see paper)
61% identity, 97% coverage of query (465 bits)
Echvi_2777 fused D-3-phosphoglycerate dehydrogenase / phosphoserine phosphatase (EC 1.1.1.95; EC 3.1.3.3) from Echinicola vietnamensis KMM 6221, DSM 17526
51% identity, 98% coverage of query (435 bits)
U3RH61 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Acanthamoeba castellanii (see paper)
50% identity, 98% coverage of query (400 bits)
SERA_YEAST / P40054 D-3-phosphoglycerate dehydrogenase 1; 3-PGDH 1; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
49% identity, 96% coverage of query (375 bits)
P87228 Putative D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
48% identity, 97% coverage of query (374 bits)
SER33_YEAST / P40510 D-3-phosphoglycerate dehydrogenase 2; 3-PGDH 2; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
47% identity, 99% coverage of query (371 bits)
6rj5A Crystal structure of phgdh in complex with compound 39
37% identity, 73% coverage of query (193 bits)
6plfA Crystal structure of human phgdh complexed with compound 1
37% identity, 73% coverage of query (193 bits)
7ewhA Crystal structure of human phgdh in complex with homoharringtonine
37% identity, 73% coverage of query (193 bits)
6rihA Crystal structure of phgdh in complex with compound 9
37% identity, 73% coverage of query (193 bits)
7dkmA / O43175 Phgdh covalently linked to oridonin (see paper)
37% identity, 73% coverage of query (192 bits)
SERA_MOUSE / Q61753 D-3-phosphoglycerate dehydrogenase; 3-PGDH; A10; EC 1.1.1.95 from Mus musculus (Mouse) (see paper)
Q61753 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mus musculus (see 2 papers)
34% identity, 85% coverage of query (192 bits)
6plgA Crystal structure of human phgdh complexed with compound 15
37% identity, 73% coverage of query (192 bits)
6rj2A Crystal structure of phgdh in complex with compound 40
37% identity, 72% coverage of query (192 bits)
6cwaA Crystal structure phgdh in complex with nadh and 3-phosphoglycerate at 1.77 a resolution
37% identity, 73% coverage of query (192 bits)
PHGDH / O43175 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) from Homo sapiens (see 3 papers)
SERA_HUMAN / O43175 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) (see 7 papers)
O43175 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Homo sapiens (see 8 papers)
37% identity, 75% coverage of query (191 bits)
6rj3A Crystal structure of phgdh in complex with compound 15
37% identity, 72% coverage of query (191 bits)
Phgdh / O08651 3-phosphoglycerate dehydrogenase subunit (EC 1.1.1.95) from Rattus norvegicus (see paper)
SERA_RAT / O08651 D-3-phosphoglycerate dehydrogenase; 3-PGDH; EC 1.1.1.95 from Rattus norvegicus (Rat) (see paper)
O08651 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Rattus norvegicus (see paper)
34% identity, 85% coverage of query (189 bits)
serA / GB|AAC83943.1 phosphoglycerate dehydrogenase; EC 1.1.1.95 from Bacillus subtilis (see paper)
serA / AAC83943.1 phosphoglycerate dehydrogenase from Bacillus subtilis (see 3 papers)
33% identity, 75% coverage of query (173 bits)
SERA2_ARATH / O04130 D-3-phosphoglycerate dehydrogenase 2, chloroplastic; PGDH; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O04130 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 3 papers)
35% identity, 78% coverage of query (164 bits)
SERA3_ARATH / Q9LT69 D-3-phosphoglycerate dehydrogenase 3, chloroplastic; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LT69 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 4 papers)
34% identity, 73% coverage of query (150 bits)
AO353_26885 phosphogluconate 2-dehydrogenase KguD (EC 1.1.1.43) from Pseudomonas fluorescens FW300-N2E3
34% identity, 73% coverage of query (148 bits)
Q608T2 hydroxypyruvate reductase (EC 1.1.1.81) from Methylococcus capsulatus (see paper)
33% identity, 74% coverage of query (147 bits)
H9JRZ9 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Bombyx mori (see paper)
32% identity, 73% coverage of query (144 bits)
kguD / Q5TM04 2-dehydro-6-phosphogluconate reductase (EC 1.1.1.43) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see 2 papers)
33% identity, 73% coverage of query (143 bits)
PS417_12555 phosphogluconate 2-dehydrogenase KguD (EC 1.1.1.43) from Pseudomonas simiae WCS417
35% identity, 71% coverage of query (141 bits)
A9ZNT9 formate dehydrogenase (EC 1.17.1.9) from Gelatoporia subvermispora (see paper)
33% identity, 71% coverage of query (135 bits)
A9ZNT8 formate dehydrogenase (EC 1.17.1.9) from Gelatoporia subvermispora (see paper)
33% identity, 71% coverage of query (134 bits)
fdh / O08375 NAD-dependent formate dehydrogenase subunit (EC 1.17.1.9) from Moraxella sp. (see 2 papers)
O08375 formate dehydrogenase (EC 1.17.1.9) from Moraxella sp. C-1 (see paper)
32% identity, 71% coverage of query (133 bits)
2gsdA / O08375 NAD-dependent formate dehydrogenase from bacterium moraxella sp.C2 in complex with NAD and azide (see paper)
32% identity, 71% coverage of query (132 bits)
3n7uA NAD-dependent formate dehydrogenase from higher-plant arabidopsis thaliana in complex with NAD and azide
31% identity, 71% coverage of query (119 bits)
3jtmA / Q9S7E4 Structure of recombinant formate dehydrogenase from arabidopsis thaliana
31% identity, 71% coverage of query (119 bits)
FDH1 / Q9S7E4 formate dehydrogenase (EC 1.17.1.9) from Arabidopsis thaliana (see 2 papers)
FDH_ARATH / Q9S7E4 Formate dehydrogenase, chloroplastic/mitochondrial; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9S7E4 formate dehydrogenase (EC 1.17.1.9) from Arabidopsis thaliana (see paper)
31% identity, 71% coverage of query (119 bits)
5dt9A / Q9KQ92 Crystal structure of a putative d-erythronate-4-phosphate dehydrogenase from vibrio cholerae
33% identity, 70% coverage of query (112 bits)
Build an alignment for WP_013835838.1 and 40 homologs with ≥ 30% identity
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FDH1_YEASC / N1P3Y5 Formate dehydrogenase 1; FDH 1; NAD-dependent formate dehydrogenase 1; EC 1.17.1.9 from Saccharomyces cerevisiae (strain CEN.PK113-7D) (Baker's yeast) (see paper)
FDH1_YEAST / Q08911 Formate dehydrogenase 1; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
28% identity, 71% coverage of query (103 bits)
PDXB_PSEAE / Q9I3W9 Erythronate-4-phosphate dehydrogenase; EC 1.1.1.290 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
Q9I3W9 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Pseudomonas aeruginosa (see paper)
2o4cA / Q9I3W9 Crystal structure of d-erythronate-4-phosphate dehydrogenase complexed with NAD (see paper)
30% identity, 77% coverage of query (96.3 bits)
6t8zAAA Formate dehydrogenase
31% identity, 71% coverage of query (95.1 bits)
6t8yBBB / G0SGU4 6t8yBBB (see paper)
31% identity, 71% coverage of query (94.7 bits)
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Lawrence Berkeley National Laboratory