Searching for up to 100 curated homologs for WP_013841723.1 NCBI__GCF_000215085.1:WP_013841723.1 (313 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
hprA / P73821 glycerate dehydrogenase (EC 1.1.1.29) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
42% identity, 97% coverage of query (247 bits)
HPR_THEMA / Q9X1C1 Hydroxypyruvate reductase; HPR; EC 1.1.1.81 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
45% identity, 95% coverage of query (245 bits)
serA / GB|AAC83943.1 phosphoglycerate dehydrogenase; EC 1.1.1.95 from Bacillus subtilis (see paper)
serA / AAC83943.1 phosphoglycerate dehydrogenase from Bacillus subtilis (see 3 papers)
42% identity, 100% coverage of query (231 bits)
1wwkA / O50095 Crystal structure of phosphoglycerate dehydrogenase from pyrococcus horikoshii ot3
44% identity, 97% coverage of query (228 bits)
SERA2_ARATH / O04130 D-3-phosphoglycerate dehydrogenase 2, chloroplastic; PGDH; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O04130 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 3 papers)
42% identity, 97% coverage of query (225 bits)
slcC / Q1QWN6 S-sulfolactate dehydrogenase subunit (EC 1.1.1.310) from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
SLCC_CHRSD / Q1QWN6 (S)-sulfolactate dehydrogenase; (2S)-3-sulfolactate dehydrogenase; (S)-sulfolactate oxidoreductase; EC 1.1.1.310 from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
43% identity, 93% coverage of query (224 bits)
H9JRZ9 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Bombyx mori (see paper)
44% identity, 83% coverage of query (220 bits)
Phgdh / O08651 3-phosphoglycerate dehydrogenase subunit (EC 1.1.1.95) from Rattus norvegicus (see paper)
SERA_RAT / O08651 D-3-phosphoglycerate dehydrogenase; 3-PGDH; EC 1.1.1.95 from Rattus norvegicus (Rat) (see paper)
O08651 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Rattus norvegicus (see paper)
40% identity, 94% coverage of query (218 bits)
A0A1Z4EAX3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Beta vulgaris (see paper)
41% identity, 97% coverage of query (218 bits)
6plgA Crystal structure of human phgdh complexed with compound 15
40% identity, 94% coverage of query (218 bits)
6rj5A Crystal structure of phgdh in complex with compound 39
40% identity, 94% coverage of query (218 bits)
6plfA Crystal structure of human phgdh complexed with compound 1
40% identity, 94% coverage of query (218 bits)
7ewhA Crystal structure of human phgdh in complex with homoharringtonine
40% identity, 94% coverage of query (218 bits)
6rihA Crystal structure of phgdh in complex with compound 9
40% identity, 94% coverage of query (218 bits)
Q9Z564 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Streptomyces coelicolor (see paper)
43% identity, 86% coverage of query (217 bits)
7dkmA / O43175 Phgdh covalently linked to oridonin (see paper)
40% identity, 94% coverage of query (217 bits)
SERA_MOUSE / Q61753 D-3-phosphoglycerate dehydrogenase; 3-PGDH; A10; EC 1.1.1.95 from Mus musculus (Mouse) (see paper)
Q61753 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mus musculus (see 2 papers)
40% identity, 94% coverage of query (217 bits)
6cwaA Crystal structure phgdh in complex with nadh and 3-phosphoglycerate at 1.77 a resolution
40% identity, 94% coverage of query (217 bits)
6rj3A Crystal structure of phgdh in complex with compound 15
40% identity, 94% coverage of query (217 bits)
6rj2A Crystal structure of phgdh in complex with compound 40
41% identity, 90% coverage of query (217 bits)
A0A2R6X868 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Marchantia polymorpha (see paper)
42% identity, 98% coverage of query (216 bits)
PHGDH / O43175 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) from Homo sapiens (see 3 papers)
SERA_HUMAN / O43175 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) (see 7 papers)
O43175 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Homo sapiens (see 8 papers)
41% identity, 90% coverage of query (216 bits)
SERA1_ARATH / O49485 D-3-phosphoglycerate dehydrogenase 1, chloroplastic; Protein EMBRYO SAC DEVELOPMENT ARREST 9; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
O49485 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 4 papers)
42% identity, 97% coverage of query (213 bits)
A0A1Z4EAX4 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Beta vulgaris (see paper)
41% identity, 97% coverage of query (211 bits)
SERA3_ARATH / Q9LT69 D-3-phosphoglycerate dehydrogenase 3, chloroplastic; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LT69 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 4 papers)
40% identity, 97% coverage of query (207 bits)
P9WNX3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mycobacterium tuberculosis (see 5 papers)
41% identity, 88% coverage of query (204 bits)
3dc2A / P9WNX3 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis (see paper)
41% identity, 88% coverage of query (204 bits)
3ddnB Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis
41% identity, 88% coverage of query (204 bits)
6plfB Crystal structure of human phgdh complexed with compound 1
40% identity, 86% coverage of query (202 bits)
5aovA / Q8U3Y2 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate (see paper)
38% identity, 88% coverage of query (185 bits)
Q8U3Y2 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus furiosus (see paper)
38% identity, 88% coverage of query (185 bits)
GYAR_THELN / Q9C4M5 Glyoxylate reductase; EC 1.1.1.26 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
Q9C4M5 glyoxylate reductase (EC 1.1.1.26) from Thermococcus litoralis (see paper)
36% identity, 97% coverage of query (181 bits)
P87228 Putative D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
37% identity, 95% coverage of query (181 bits)
hprA / Q59516 hydroxypyruvate reductase subunit (EC 1.1.1.81) from Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) (see 2 papers)
37% identity, 86% coverage of query (177 bits)
F8AEA4 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus yayanosii (see paper)
35% identity, 99% coverage of query (175 bits)
6biiA / F8AEA4 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) (see paper)
35% identity, 99% coverage of query (175 bits)
SER33_YEAST / P40510 D-3-phosphoglycerate dehydrogenase 2; 3-PGDH 2; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
33% identity, 97% coverage of query (174 bits)
SERA_YEAST / P40054 D-3-phosphoglycerate dehydrogenase 1; 3-PGDH 1; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
34% identity, 97% coverage of query (174 bits)
U3RH61 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Acanthamoeba castellanii (see paper)
34% identity, 92% coverage of query (173 bits)
Q608T2 hydroxypyruvate reductase (EC 1.1.1.81) from Methylococcus capsulatus (see paper)
36% identity, 92% coverage of query (171 bits)
YOAD_BACSU / O34815 Putative 2-hydroxyacid dehydrogenase YoaD; EC 1.1.1.- from Bacillus subtilis (strain 168) (see paper)
34% identity, 92% coverage of query (162 bits)
HPR_BLAHS / C0CMQ8 Hydroxypyruvate reductase; EC 1.1.1.81 from Blautia hydrogenotrophica (strain DSM 10507 / JCM 14656 / S5a33) (Ruminococcus hydrogenotrophicus) (see paper)
33% identity, 98% coverage of query (155 bits)
SerA / b2913 phosphoglycerate dehydrogenase (EC 1.1.1.95; EC 1.1.1.399) from Escherichia coli K-12 substr. MG1655 (see 36 papers)
serA / P0A9T0 phosphoglycerate dehydrogenase (EC 1.1.1.95; EC 1.1.1.399) from Escherichia coli (strain K12) (see 36 papers)
SERA_ECOLI / P0A9T0 D-3-phosphoglycerate dehydrogenase; PGDH; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Escherichia coli (strain K12) (see paper)
C3SVM7 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escherichia coli (see paper)
P0A9T0 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escherichia coli (see 7 papers)
serA / RF|NP_417388 D-3-phosphoglycerate dehydrogenase; EC 1.1.1.95 from Escherichia coli K12 (see 5 papers)
33% identity, 92% coverage of query (154 bits)
2p9eA / P0A9T0 Crystal structure of g336v mutant of e.Coli phosphoglycerate dehydrogenase (see paper)
33% identity, 92% coverage of query (154 bits)
1ybaA The active form of phosphoglycerate dehydrogenase
33% identity, 92% coverage of query (154 bits)
1psdA The allosteric ligand site in the vmax-type cooperative enzyme phosphoglycerate dehydrogenase
33% identity, 92% coverage of query (154 bits)
O66939 D-lactate dehydrogenase (EC 1.1.1.28) from Aquifex aeolicus (see paper)
3kb6B / O66939 Crystal structure of d-lactate dehydrogenase from aquifex aeolicus complexed with NAD and lactic acid (see paper)
36% identity, 81% coverage of query (153 bits)
Q9I6H5 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pseudomonas aeruginosa (see paper)
34% identity, 96% coverage of query (153 bits)
Echvi_2777 fused D-3-phosphoglycerate dehydrogenase / phosphoserine phosphatase (EC 1.1.1.95; EC 3.1.3.3) from Echinicola vietnamensis KMM 6221, DSM 17526
33% identity, 94% coverage of query (153 bits)
Q972A9 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Sulfurisphaera tokodaii (see paper)
35% identity, 95% coverage of query (150 bits)
A4VGK3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pseudomonas stutzeri (see paper)
33% identity, 96% coverage of query (150 bits)
2eklA / Q972A9 Structure of st1218 protein from sulfolobus tokodaii
35% identity, 95% coverage of query (150 bits)
BPHYT_RS11290 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) from Burkholderia phytofirmans PsJN
35% identity, 97% coverage of query (150 bits)
2dbqA / O58320 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) (see paper)
34% identity, 99% coverage of query (149 bits)
O58320 Glyoxylate reductase; EC 1.1.1.26 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
34% identity, 99% coverage of query (149 bits)
6cdfA / Q13363 Human ctbp1 (28-378) (see paper)
30% identity, 94% coverage of query (145 bits)
1hl3A Ctbp/bars in ternary complex with NAD(h) and pidlskk peptide
30% identity, 94% coverage of query (145 bits)
1hkuA Ctbp/bars: a dual-function protein involved in transcription corepression and golgi membrane fission
30% identity, 94% coverage of query (145 bits)
6v89A Human ctbp1 (28-375) in complex with amp
30% identity, 94% coverage of query (145 bits)
CTBP2_XENLA / Q9W758 C-terminal-binding protein 2; CtBP2; C-terminal-binding protein B; TCF-3 corepressor CtBP; XCtBP from Xenopus laevis (African clawed frog) (see paper)
30% identity, 93% coverage of query (144 bits)
4lceA Ctbp1 in complex with substrate mtob
30% identity, 94% coverage of query (144 bits)
4u6sA Ctbp1 in complex with substrate phenylpyruvate
30% identity, 94% coverage of query (144 bits)
4u6qA Ctbp1 bound to inhibitor 2-(hydroxyimino)-3-phenylpropanoic acid
30% identity, 94% coverage of query (144 bits)
CTBP_DROME / O46036 C-terminal-binding protein; CtBP protein; dCtBP from Drosophila melanogaster (Fruit fly) (see 2 papers)
32% identity, 94% coverage of query (143 bits)
F8A9V0 D-lactate dehydrogenase (EC 1.1.1.28) from Thermodesulfatator indicus (see paper)
35% identity, 73% coverage of query (143 bits)
CTBP1_RAT / Q9Z2F5 C-terminal-binding protein 1; CtBP1; 50 kDa BFA-dependent ADP-ribosylation substrate; BARS-50; C-terminal-binding protein 3; CtBP3; EC 1.1.1.- from Rattus norvegicus (Rat) (see 6 papers)
30% identity, 94% coverage of query (143 bits)
CTBP1_MOUSE / O88712 C-terminal-binding protein 1; CtBP1; EC 1.1.1.- from Mus musculus (Mouse) (see 11 papers)
30% identity, 94% coverage of query (143 bits)
Build an alignment for WP_013841723.1 and 67 homologs with ≥ 30% identity
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CTBP1 / Q13363 C-terminal-binding protein 1 (EC 1.1.1.428) from Homo sapiens (see 22 papers)
CTBP1_HUMAN / Q13363 C-terminal-binding protein 1; CtBP1; EC 1.1.1.- from Homo sapiens (Human) (see 24 papers)
29% identity, 94% coverage of query (142 bits)
8atiA / P56545 Human ctbp2(31-364) in complex with rai2 peptide(315-322)
31% identity, 94% coverage of query (142 bits)
4lcjA Ctbp2 in complex with substrate mtob
31% identity, 94% coverage of query (142 bits)
CTBP2_HUMAN / P56545 C-terminal-binding protein 2; CtBP2 from Homo sapiens (Human) (see 5 papers)
31% identity, 94% coverage of query (141 bits)
CTBP2_RAT / Q9EQH5 C-terminal-binding protein 2; CtBP2 from Rattus norvegicus (Rat) (see paper)
31% identity, 94% coverage of query (141 bits)
CTBP2_BOVIN / Q0VCQ1 C-terminal-binding protein 2; CtBP2 from Bos taurus (Bovine) (see paper)
31% identity, 94% coverage of query (141 bits)
CTBP2_MOUSE / P56546 C-terminal-binding protein 2; CtBP2 from Mus musculus (Mouse) (see 4 papers)
31% identity, 94% coverage of query (141 bits)
6ttbA / A0A0H3JSR9 Crystal structure of NAD-dependent formate dehydrogenase from staphylococcus aureus in complex with NAD
34% identity, 78% coverage of query (137 bits)
2gcgA / Q9UBQ7 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase (see paper)
32% identity, 95% coverage of query (135 bits)
CTBP1_CAEEL / Q20595 C-terminal-binding protein 1 from Caenorhabditis elegans (see 4 papers)
32% identity, 94% coverage of query (135 bits)
GRHPR / Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.81; EC 1.1.1.79) from Homo sapiens (see 2 papers)
GRHPR_HUMAN / Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) (see 4 papers)
Q9UBQ7 glyoxylate reductase (EC 1.1.1.26); glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Homo sapiens (see 2 papers)
32% identity, 95% coverage of query (135 bits)
5z20F / Q9I530 The ternary structure of d-lactate dehydrogenase from pseudomonas aeruginosa with nadh and oxamate (see paper)
34% identity, 71% coverage of query (135 bits)
4cukA / Q8Z780 Structure of salmonella d-lactate dehydrogenase in complex with nadh
32% identity, 79% coverage of query (134 bits)
5dt9A / Q9KQ92 Crystal structure of a putative d-erythronate-4-phosphate dehydrogenase from vibrio cholerae
34% identity, 94% coverage of query (131 bits)
7arzA / A9SQZ2 Ternary complex of NAD-dependent formate dehydrogenase from physcomitrium patens
33% identity, 83% coverage of query (130 bits)
4zgsA / B0LUZ5 Identification of the pyruvate reductase of chlamydomonas reinhardtii (see paper)
34% identity, 72% coverage of query (128 bits)
1sc6D / P0A9T0 Crystal structure of w139g d-3-phosphoglycerate dehydrogenase complexed with NAD+ (see paper)
31% identity, 92% coverage of query (125 bits)
FDH1_YEASC / N1P3Y5 Formate dehydrogenase 1; FDH 1; NAD-dependent formate dehydrogenase 1; EC 1.17.1.9 from Saccharomyces cerevisiae (strain CEN.PK113-7D) (Baker's yeast) (see paper)
FDH1_YEAST / Q08911 Formate dehydrogenase 1; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
30% identity, 93% coverage of query (122 bits)
4prlA Crystal structure of d-lactate dehydrogenase with NAD+ from lactobacillus jensenii (see paper)
32% identity, 80% coverage of query (122 bits)
6ih6A / G4XDR8 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide
29% identity, 98% coverage of query (118 bits)
FDH1 / O13437 formate dehydrogenase (EC 1.17.1.9) from Candida boidinii (see 3 papers)
FDH_CANBO / O13437 Formate dehydrogenase; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Candida boidinii (Yeast) (see 6 papers)
O13437 formate dehydrogenase (EC 1.17.1.9) from [Candida] boidinii (see 12 papers)
fdh3 / CAB54834.1 formate dehydrogenase from [Candida] boidinii (see paper)
31% identity, 84% coverage of query (118 bits)
3oetH / P60802 D-erythronate-4-phosphate dehydrogenase complexed with NAD
33% identity, 94% coverage of query (116 bits)
6d4bA / A0A0A1EQY0 Crystal structure of candida boidinii formate dehydrogenase v123a mutant complexed with NAD+ and azide
29% identity, 93% coverage of query (115 bits)
8j3oB Formate dehydrogenase wild-type enzyme from candida dubliniensis complexed with nadh
28% identity, 94% coverage of query (112 bits)
8j3oA Formate dehydrogenase wild-type enzyme from candida dubliniensis complexed with nadh
28% identity, 94% coverage of query (112 bits)
3n7uA NAD-dependent formate dehydrogenase from higher-plant arabidopsis thaliana in complex with NAD and azide
33% identity, 70% coverage of query (112 bits)
3jtmA / Q9S7E4 Structure of recombinant formate dehydrogenase from arabidopsis thaliana
33% identity, 70% coverage of query (112 bits)
FDH1 / Q9S7E4 formate dehydrogenase (EC 1.17.1.9) from Arabidopsis thaliana (see 2 papers)
FDH_ARATH / Q9S7E4 Formate dehydrogenase, chloroplastic/mitochondrial; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9S7E4 formate dehydrogenase (EC 1.17.1.9) from Arabidopsis thaliana (see paper)
33% identity, 70% coverage of query (112 bits)
DHD2_LACPA / P17584 D-2-hydroxyisocaproate dehydrogenase; D-HICDH; EC 1.1.1.- from Lacticaseibacillus paracasei (Lactobacillus paracasei) (see paper)
P17584 D-2-hydroxyacid dehydrogenase (NAD+) (EC 1.1.1.345) from Lacticaseibacillus paracasei (see 2 papers)
CH_091798 D-2-hydroxyisocaproate dehydrogenase; EC 1.1.1.- from Lactobacillus paracasei (see 2 papers)
28% identity, 86% coverage of query (111 bits)
6t8zAAA Formate dehydrogenase
31% identity, 86% coverage of query (111 bits)
1dxyA / P17584 Structure of d-2-hydroxyisocaproate dehydrogenase (see paper)
28% identity, 86% coverage of query (111 bits)
6t8yBBB / G0SGU4 6t8yBBB (see paper)
31% identity, 86% coverage of query (111 bits)
5z21B / Q8RG11 The ternary structure of d-lactate dehydrogenase from fusobacterium nucleatum with nadh and oxamate (see paper)
31% identity, 72% coverage of query (110 bits)
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