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Searching for up to 100 curated homologs for WP_013842627.1 NCBI__GCF_000215085.1:WP_013842627.1 (433 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DVU_3028 / Q726S8 quinone-dependent D-lactate dehydrogenase iron-sulfur subunit (EC 1.1.2.5) from Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) (see 3 papers)
    35% identity, 94% coverage of query (255 bits)

DVU_3033 / Q726S3 quinone-dependent L-lactate dehydrogenase large subunit (EC 1.1.2.3) from Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) (see 4 papers)
    30% identity, 93% coverage of query (197 bits)

Build an alignment

Build an alignment for WP_013842627.1 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

SMc00926 D-lactate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6) from Sinorhizobium meliloti 1021
    27% identity, 95% coverage of query (161 bits)

RR42_RS17315 D-lactate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6) from Cupriavidus basilensis FW507-4G11
    27% identity, 95% coverage of query (142 bits)

Psest_3839 D-lactate/glycolate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6; EC 1.1.99.14) from Pseudomonas stutzeri RCH2
    28% identity, 95% coverage of query (140 bits)

PGA1_c29700 D-lactate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6) from Phaeobacter inhibens BS107
    27% identity, 95% coverage of query (140 bits)

TFRB_METTM / D9PUX5 Fumarate reductase (CoM/CoB) subunit B; Thiol:fumarate reductase subunit B; EC 1.3.4.1 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see 2 papers)
    28% identity, 95% coverage of query (137 bits)

hdrD / P96797 CoB-CoM heterodisulfide reductase catalytic subunit D (EC 1.8.98.1) from Methanosarcina barkeri (strain Fusaro / DSM 804) (see 2 papers)
HDRD_METBF / P96797 Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D; CoB--CoM heterodisulfide reductase iron-sulfur subunit D; Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D; EC 1.8.98.1 from Methanosarcina barkeri (strain Fusaro / DSM 804) (see 2 papers)
TC 3.D.7.1.1 / P96797 HDRD, component of H2:heterodisulfide oxidoreductase, HHO. Two protons are consumed in the cytoplasm while two protons are released in the periplasm, contributing to the pmf from Methanosarcina barkeri (see 3 papers)
hdrD / GB|AAZ70545.1 CoB--CoM heterodisulfide reductase iron-sulfur subunit D; EC 1.8.98.1 from Methanosarcina barkeri str. Fusaro (see 3 papers)
    25% identity, 94% coverage of query (133 bits)

GlpC / b2243 anaerobic glycerol-3-phosphate dehydrogenase subunit C (EC 1.1.5.3) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
glpC / P0A996 anaerobic glycerol-3-phosphate dehydrogenase subunit C (EC 1.1.5.3) from Escherichia coli (strain K12) (see 4 papers)
    27% identity, 89% coverage of query (132 bits)

YghL / b4467 glycolate dehydrogenase, putative iron-sulfur subunit (EC 1.1.99.14) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
glcF / P52074 glycolate dehydrogenase, putative iron-sulfur subunit (EC 1.1.99.14) from Escherichia coli (strain K12) (see 4 papers)
GLCF_ECOLI / P52074 Glycolate oxidase iron-sulfur subunit; Glycolate dehydrogenase subunit GlcF; Glycolate oxidase subunit GlcF; EC 1.1.99.14 from Escherichia coli (strain K12) (see 4 papers)
glcF / RF|YP_026190.1 glycolate oxidase, iron-sulfur subunit from Escherichia coli K12 (see paper)
glcF / AAB02532.1 glycolate oxidase subunit, (Fe-S)protein from Escherichia coli (see paper)
    25% identity, 95% coverage of query (125 bits)

HDRD_METMA / Q8PVW3 Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D; CoB--CoM heterodisulfide reductase iron-sulfur subunit D; Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D; EC 1.8.98.1 from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) (see paper)
    24% identity, 94% coverage of query (124 bits)

HDRD_METTT / A0A0E3NEE1 Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D; CoB--CoM heterodisulfide reductase iron-sulfur subunit D; Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D; EC 1.8.98.1 from Methanosarcina thermophila (strain ATCC 43570 / DSM 1825 / OCM 12 / VKM B-1830 / TM-1) (see 3 papers)
    24% identity, 94% coverage of query (114 bits)

BPHYT_RS03150 Phosphoglycerate dehydrogenase (EC:1.1.1.95) from Burkholderia phytofirmans PsJN
    24% identity, 86% coverage of query (90.1 bits)

HSERO_RS19500 Putative phosphoglycerate dehydrogenase (EC:1.1.1.95) from Herbaspirillum seropedicae SmR1
    23% identity, 88% coverage of query (87.0 bits)

ETFQR_SYNWW / Q0AZ32 EtfAB:quinone oxidoreductase; EC 1.18.-.- from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) (see 2 papers)
    22% identity, 82% coverage of query (66.6 bits)

ETFFR_CHRSD / Q1QYW0 Probable membrane-anchored ferredoxin csal_0991; Transmembrane clostridial-type ferredoxin; EC 1.-.-.- from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
    22% identity, 88% coverage of query (63.5 bits)

tmcB / Q72FF0 Tmc electron transfer complex B subunit from Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) (see 8 papers)
TC 5.B.11.1.1 / Q72FF0 Ferredoxin, 4Fe-4S, putative, component of Pentameric transmembrane electron flow carrier complex, TmcA2BCD from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
    20% identity, 92% coverage of query (61.2 bits)

Pf6N2E2_4704 Dimethylglycine dehydrogenase (ferredoxin), FeS subunit DgcB (EC 1.5.7.-) from Pseudomonas fluorescens FW300-N2E2
    24% identity, 91% coverage of query (60.8 bits)

FADF_BACSU / P45866 Probable iron-sulfur-binding oxidoreductase FadF; EC 1.-.-.- from Bacillus subtilis (strain 168) (see paper)
    21% identity, 89% coverage of query (58.5 bits)

AO353_07705 DgcB Dimethylglycine demethylase subunit B (EC 1.5.3.-) from Pseudomonas fluorescens FW300-N2E3
    24% identity, 88% coverage of query (58.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory