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Searching for up to 100 curated homologs for WP_014148255.1 NCBI__GCF_000968535.2:WP_014148255.1 (291 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DAPA_PSEAE / Q9I4W3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I4W3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Pseudomonas aeruginosa (see 2 papers)
    64% identity, 100% coverage of query (374 bits)

3puoA / Q9I4W3 Crystal structure of dihydrodipicolinate synthase from pseudomonas aeruginosa(psdhdps)complexed with l-lysine at 2.65a resolution (see paper)
    64% identity, 100% coverage of query (364 bits)

3s8hA Structure of dihydrodipicolinate synthase complexed with 3- hydroxypropanoic acid(hpa)at 2.70 a resolution
    64% identity, 100% coverage of query (364 bits)

4dxvA / D0CFC3 Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
    59% identity, 100% coverage of query (345 bits)

3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
    59% identity, 100% coverage of query (345 bits)

3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
    59% identity, 100% coverage of query (345 bits)

3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
    59% identity, 100% coverage of query (345 bits)

3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
    59% identity, 100% coverage of query (345 bits)

3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
    59% identity, 100% coverage of query (345 bits)

4pfmA / A9DKW4 Shewanella benthica dhdps with lysine and pyruvate
    56% identity, 100% coverage of query (336 bits)

DapA / b2478 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli K-12 substr. MG1655 (see 24 papers)
dapA / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (strain K12) (see 23 papers)
DAPA_ECOLI / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 11 papers)
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (see 15 papers)
    55% identity, 100% coverage of query (335 bits)

5t25A / B7M7I1 Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
    55% identity, 100% coverage of query (335 bits)

2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
    55% identity, 100% coverage of query (335 bits)

3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site.
    54% identity, 100% coverage of query (334 bits)

A5F699 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Vibrio cholerae (see paper)
    55% identity, 99% coverage of query (328 bits)

dhdps / CAC50571.1 dihydrodipicolinate synthetase from Yersinia enterocolitica (see paper)
    54% identity, 100% coverage of query (325 bits)

DAPA_NEIMB / Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Neisseria meningitidis serogroup B (strain MC58) (see paper)
Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Neisseria meningitidis (see paper)
    49% identity, 99% coverage of query (285 bits)

O67216 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Aquifex aeolicus (see paper)
    48% identity, 100% coverage of query (271 bits)

Q8RBI5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
    47% identity, 100% coverage of query (270 bits)

DAPA_RHIML / Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see 2 papers)
Q07607 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Sinorhizobium meliloti (see 2 papers)
    44% identity, 100% coverage of query (254 bits)

dapA / Q65JG7 dihydrodipicolinate synthase subunit (EC 4.3.3.7) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see paper)
    48% identity, 92% coverage of query (253 bits)

DAPA_AGRFC / Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see 2 papers)
    44% identity, 100% coverage of query (253 bits)

4i7wA Agrobacterium tumefaciens dhdps with lysine and pyruvate
    43% identity, 100% coverage of query (251 bits)

dapA / Q04796 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacillus subtilis (strain 168) (see paper)
    46% identity, 92% coverage of query (245 bits)

DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
    40% identity, 100% coverage of query (243 bits)

1o5kA / Q9X1K9 Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
    40% identity, 100% coverage of query (243 bits)

DAPA_METJA / Q57695 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    45% identity, 100% coverage of query (241 bits)

7lvlA / A0A0F4VK59 Dihydrodipicolinate synthase bound with allosteric inhibitor (s)- lysine from candidatus liberibacter solanacearum
    43% identity, 95% coverage of query (229 bits)

Q6G468 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bartonella henselae (see paper)
    42% identity, 100% coverage of query (229 bits)

7mjfA Crystal structure of candidatus liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
    43% identity, 95% coverage of query (229 bits)

dapA2 dihydrodipicolinate synthase; EC 4.2.1.52 from Bacillus anthracis (see paper)
    43% identity, 96% coverage of query (227 bits)

4m19A Dihydrodipicolinate synthase from c. Jejuni with pyruvate bound to the active site and lysine bound to allosteric site
    42% identity, 100% coverage of query (221 bits)

5ktlA / Q3M723 Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
    40% identity, 98% coverage of query (220 bits)

Q3M723 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Trichormus variabilis (see paper)
    40% identity, 98% coverage of query (220 bits)

6u01B Dihydrodipicolinate synthase (dhdps) from c.Jejuni, n84d mutant with pyruvate bound in the active site
    42% identity, 100% coverage of query (219 bits)

7kkdB / Q9PPB4 Dihydrodipicolinate synthase (dhdps) from c.Jejuni, n84a mutant with pyruvate bound in the active site and r,r-bislysine bound at the allosteric site
    42% identity, 100% coverage of query (218 bits)

7kg2A Dihydrodipicolinate synthase (dhdps) from c.Jejuni, h59k mutant with pyruvate bound in the active site and l-histidine bound at the allosteric site
    42% identity, 100% coverage of query (218 bits)

5ud6C / M1V4H9 Crystal structure of dhdps from cyanidioschyzon merolae with lysine bound
    42% identity, 98% coverage of query (213 bits)

4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
    41% identity, 95% coverage of query (206 bits)

dapA / CAA92211.1 dihydrodipicolinate synthase from Prochlorococcus marinus (see paper)
    42% identity, 91% coverage of query (188 bits)

DAPA_STAAR / Q6GH13 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Staphylococcus aureus (strain MRSA252) (see paper)
Q6GH13 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Staphylococcus aureus (see 2 papers)
    37% identity, 98% coverage of query (187 bits)

3di1B / Q5HG25 Crystal structure of the staphylococcus aureus dihydrodipicolinate synthase-pyruvate complex (see paper)
    37% identity, 97% coverage of query (186 bits)

DAPA_STAAC / Q5HG25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Staphylococcus aureus (strain COL) (see paper)
Q5HG25 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Staphylococcus aureus (see paper)
    37% identity, 97% coverage of query (186 bits)

dapA / P19808 dihydropicolinate synthase subunit (EC 4.3.3.7) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
P19808 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Corynebacterium glutamicum (see paper)
dapA / CAA79714.1 dihydrodipicolinate synthase from Corynebacterium glutamicum (see paper)
    38% identity, 98% coverage of query (173 bits)

5j5dA / P9WP25 Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
    34% identity, 98% coverage of query (169 bits)

DAPA_MYCTU / P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
    34% identity, 98% coverage of query (168 bits)

1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis
    34% identity, 98% coverage of query (168 bits)

3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
    34% identity, 98% coverage of query (168 bits)

P24846 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Triticum aestivum (see paper)
    37% identity, 92% coverage of query (159 bits)

7mdsA Crystal structure of atdhdps1 in complex with mbdta-2
    35% identity, 91% coverage of query (155 bits)

6vvhBBB / Q9LZX6 thaliana dihydrodipicolinate synthase isoform 1 (dhdps1) in complex with lysine (see paper)
    35% identity, 91% coverage of query (154 bits)

Q9FVC8 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Arabidopsis thaliana (see paper)
    35% identity, 91% coverage of query (154 bits)

5ui3C Crystal structure of dhdps from chlamydomonas reinhardtii
    33% identity, 93% coverage of query (147 bits)

4hnnF / D7U7T8 Dihydrodipicolinate synthase from the common grapevine with pyruvate and lysine (see paper)
    33% identity, 91% coverage of query (146 bits)

YjhH / b4298 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yjhH / P39359 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli (strain K12) (see 7 papers)
YJHH_ECOLI / P39359 Probable 2-dehydro-3-deoxy-D-pentonate aldolase YjhH; EC 4.1.2.28 from Escherichia coli (strain K12) (see paper)
    31% identity, 92% coverage of query (138 bits)

DAPAL_RHIML / O69782 Uncharacterized DapA-like lyase; EC 4.-.-.- from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
    31% identity, 99% coverage of query (130 bits)

3na8A / Q9I6R5 Crystal structure of a putative dihydrodipicolinate synthetase from pseudomonas aeruginosa
    30% identity, 95% coverage of query (130 bits)

YagE / b0268 CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2.28; EC 4.1.2.51) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yagE / P75682 CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2.28; EC 4.1.2.51) from Escherichia coli (strain K12) (see 8 papers)
YAGE_ECOLI / P75682 Putative 2-dehydro-3-deoxy-D-gluconate aldolase YagE; KDG aldolase YagE; Putative 2-dehydro-3-deoxy-D-pentonate aldolase YagE; EC 4.1.2.51; EC 4.1.2.28 from Escherichia coli (strain K12) (see 4 papers)
P75682 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20) from Escherichia coli (see paper)
    31% identity, 84% coverage of query (127 bits)

3nevA / P75682 Crystal structure of yage, a prophage protein from e. Coli k12 in complex with kdgal (see paper)
    31% identity, 84% coverage of query (127 bits)

4ptnA Crystal structure of yage, a kdg aldolase protein in complex with magnesium cation coordinated l-glyceraldehyde
    31% identity, 84% coverage of query (127 bits)

4onvA Crystal structure of yage, a kdg aldolase protein in complex with 2- keto-3-deoxy gluconate
    31% identity, 84% coverage of query (127 bits)

4oe7D Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
    31% identity, 84% coverage of query (127 bits)

4oe7B Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
    31% identity, 84% coverage of query (127 bits)

4oe7A Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
    31% identity, 84% coverage of query (127 bits)

A9CFV4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
    30% identity, 95% coverage of query (120 bits)

Build an alignment

Build an alignment for WP_014148255.1 and 65 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

Q8NMD2 N-acetylneuraminate lyase (EC 4.1.3.3) from Corynebacterium glutamicum (see paper)
    29% identity, 83% coverage of query (115 bits)

8u8wA / A0A0H3FJT8 Crystal structure of n-acetylneuraminate lyase (nana) from klebsiella aerogenes (pyruvate and halides bound)
    31% identity, 78% coverage of query (114 bits)

Q7D3Z9 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
    28% identity, 92% coverage of query (114 bits)

Npl / b3225 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli K-12 substr. MG1655 (see 21 papers)
nanA / P0A6L4 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli (strain K12) (see 30 papers)
NANA_ECOLI / P0A6L4 N-acetylneuraminate lyase; AcNeu lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NALase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Escherichia coli (strain K12) (see 8 papers)
P0A6L4 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli (see 4 papers)
nanA N-acetylneuraminate lyase; EC 4.1.3.3 from Escherichia coli K12 (see 6 papers)
    30% identity, 78% coverage of query (114 bits)

2wpbA / P0A6L4 Crystal structure of the e192n mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2r,3r)-2,3,4- trihydroxy-n,n-dipropylbutanamide in space group p21 crystal form i (see paper)
    30% identity, 78% coverage of query (114 bits)

3lbcD D-sialic acid aldolase complexed with l-arabinose
    30% identity, 78% coverage of query (114 bits)

5c55A / Q8NMD2 Crystal structure of the y138f mutant of c.Glutamicum n- acetylneuraminic acid lyase in complex with pyruvate
    29% identity, 83% coverage of query (113 bits)

1fdzA N-acetylneuraminate lyase in complex with pyruvate via borohydride reduction
    29% identity, 78% coverage of query (111 bits)

1fdyA N-acetylneuraminate lyase in complex with hydroxypyruvate
    29% identity, 78% coverage of query (111 bits)

4bwlC Structure of the y137a mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate, n-acetyl-d-mannosamine and n- acetylneuraminic acid
    29% identity, 78% coverage of query (110 bits)

4bwlA Structure of the y137a mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate, n-acetyl-d-mannosamine and n- acetylneuraminic acid
    29% identity, 78% coverage of query (110 bits)

nanA / Q9S4K9 N-acetylneuraminate lyase (EC 4.1.3.3) from Clostridium perfringens (strain 13 / Type A) (see 6 papers)
NANA_CLOPE / Q9S4K9 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Clostridium perfringens (strain 13 / Type A) (see 3 papers)
nanA / GB|CAA73375.1 N-acetylneuraminate lyase; EC 4.1.3.3 from Clostridium perfringens (see 4 papers)
    29% identity, 95% coverage of query (109 bits)

nanA sialic acid lyase from Clostridium perfringens (see paper)
    29% identity, 95% coverage of query (109 bits)

KDGA_PICTO / Q6KZI8 2-dehydro-3-deoxy-D-gluconate/2-dehydro-3-deoxy-phosphogluconate aldolase; 2-dehydro-3-deoxy-galactonate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.14; EC 4.1.2.51; EC 4.1.2.-; EC 4.1.2.21 from Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3) (see paper)
Q6KZI8 2-dehydro-3-deoxy-D-gluconate aldolase (EC 4.1.2.51) from Picrophilus torridus (see paper)
    29% identity, 90% coverage of query (107 bits)

Q8A3Z0 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacteroides thetaiotaomicron (see paper)
    27% identity, 84% coverage of query (102 bits)

HOGA1_EMENI / Q5BD77 Probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; EC 4.1.3.16 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
AN1503 dihydrodipicolinate synthase-like protein AN1503; EC 4.-.-.- from Emericella nidulans (see paper)
    31% identity, 89% coverage of query (97.8 bits)

kdgD / Q6FFQ1 5-dehydro-4-deoxyglucarate dehydratase subunit (EC 4.2.1.41) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
KDGD_ACIAD / Q6FFQ1 Probable 5-dehydro-4-deoxyglucarate dehydratase; 5-keto-4-deoxy-glucarate dehydratase; KDGDH; EC 4.2.1.41 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ1 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Acinetobacter baylyi (see 2 papers)
    30% identity, 75% coverage of query (94.4 bits)

NANA_STAA8 / Q2G160 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 4 papers)
NANA_STAAR / Q6GK01 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Staphylococcus aureus (strain MRSA252) (see paper)
Q2G160 N-acetylneuraminate lyase (EC 4.1.3.3) from Staphylococcus aureus (see 2 papers)
Q6GK01 N-acetylneuraminate lyase (EC 4.1.3.3) from Staphylococcus aureus (see paper)
    28% identity, 79% coverage of query (92.8 bits)

NANA_LACPL / P59407 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) (see paper)
    28% identity, 92% coverage of query (92.0 bits)

A0A2P1G7E2 N-acetylneuraminate lyase (EC 4.1.3.3) from Mycoplasma sp. (see paper)
    28% identity, 79% coverage of query (91.3 bits)

PP_3599 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Pseudomonas putida KT2440
    26% identity, 95% coverage of query (90.9 bits)

CH_124068 putative dihydrodipicolinate synthase from Magnaporthe grisea 70-15 (see paper)
    29% identity, 83% coverage of query (90.9 bits)

HSERO_RS15785 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Herbaspirillum seropedicae SmR1
    28% identity, 75% coverage of query (89.4 bits)

SSA_0078 / A3CK37 N-acetylneuraminate lyase subunit (EC 4.1.3.3) from Streptococcus sanguinis (strain SK36) (see 3 papers)
    25% identity, 98% coverage of query (88.6 bits)

NANA_PASMU / Q9CKB0 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetyl-D-neuraminic acid lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Pasteurella multocida (strain Pm70) (see paper)
Q9CKB0 N-acetylneuraminate lyase (EC 4.1.3.3) from Pasteurella multocida (see 2 papers)
    26% identity, 93% coverage of query (88.2 bits)

4woqC / D5Q364 Crystal structures of cdnal from clostridium difficile in complex with ketobutyric
    29% identity, 71% coverage of query (87.0 bits)

4wozB Crystal structures of cdnal from clostridium difficile in complex with mannosamine
    29% identity, 71% coverage of query (87.0 bits)

1f74A / P44539 Crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form ii complexed with 4-deoxy-sialic acid (see paper)
    26% identity, 93% coverage of query (85.9 bits)

4imgA / Q9CKB0 Crystal structure of pasteurella multocida n-acetyl-d-neuraminic acid lyase k164 mutant complexed with n-glycolylneuraminic acid (see paper)
    26% identity, 93% coverage of query (85.9 bits)

1f7bA Crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form ii in complex with 4-oxo-sialic acid
    26% identity, 93% coverage of query (85.9 bits)

4imfA Crystal structure of pasteurella multocida n-acetyl-d-neuraminic acid lyase k164 mutant complexed with n-acetylneuraminic acid
    26% identity, 93% coverage of query (85.9 bits)

B9DIJ2 N-acetylneuraminate lyase (EC 4.1.3.3) from Staphylococcus carnosus (see paper)
    26% identity, 79% coverage of query (85.5 bits)

NANA_HAEIN / P44539 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
    26% identity, 93% coverage of query (85.1 bits)

NANA_FUSNN / Q8RDN6 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) (see paper)
    25% identity, 79% coverage of query (84.7 bits)

Q7D0E8 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
    34% identity, 87% coverage of query (84.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory