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Searching for up to 100 curated homologs for WP_014267864.1 NCBI__GCF_000178955.2:WP_014267864.1 (206 a.a.)

Found high-coverage hits (≥70%) to 76 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YqaB / b2690 fructose-1-phosphate phosphatase YqaB from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yqaB / P77475 fructose-1-phosphate phosphatase YqaB from Escherichia coli (strain K12) (see 3 papers)
YQAB_ECOLI / P77475 Fructose-1-phosphate phosphatase YqaB; Fructose-1-phosphatase; EC 3.1.3.- from Escherichia coli (strain K12) (see 2 papers)
yqaB / RF|NP_417175 phosphatase yqaB; EC 3.1.3.- from Escherichia coli K12 (see 5 papers)
    36% identity, 88% coverage of query (106 bits)

P1254_THEMA / Q9X0Y1 Phosphorylated carbohydrates phosphatase TM_1254; EC 3.1.3.- from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9X0Y1 sugar-terminal-phosphatase (EC 3.1.3.58) from Thermotoga maritima (see paper)
    33% identity, 87% coverage of query (98.6 bits)

3dv9A / A6L7P8 Putative beta-phosphoglucomutase from bacteroides vulgatus.
    32% identity, 88% coverage of query (85.9 bits)

vldH / Q15JF8 validoxylamine A 7'-phosphate phosphatase (EC 3.1.3.101) from Streptomyces hygroscopicus subsp. limoneus (see 2 papers)
VLDH_STRHL / Q15JF8 Validoxylamine A 7'-phosphate phosphatase; Phosphomutase; EC 3.1.3.101 from Streptomyces hygroscopicus subsp. limoneus (see 2 papers)
Q15JF8 validoxylamine A 7'-phosphate phosphatase (EC 3.1.3.101) from Streptomyces hygroscopicus subsp. limoneus (see 2 papers)
    31% identity, 94% coverage of query (85.5 bits)

Q6FBP5 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17); mannitol-1-phosphatase (EC 3.1.3.22) from Acinetobacter baylyi (see paper)
    31% identity, 90% coverage of query (83.6 bits)

Build an alignment

Build an alignment for WP_014267864.1 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

3qypB / Q8A5V9 Crystal structure of pyrophosphatase from bacteroides thetaiotaomicron, glu47asn mutant complexed with calcium and phosphate (see paper)
    29% identity, 88% coverage of query (79.0 bits)

Q8A5V9 inorganic diphosphatase (EC 3.6.1.1) from Bacteroides thetaiotaomicron (see paper)
    29% identity, 88% coverage of query (77.8 bits)

3qu2A Crystal structure of pyrophosphatase from bacteroides thetaiotaomicron, a closed cap conformation
    29% identity, 88% coverage of query (77.8 bits)

PGMB_BACSU / O06995 Beta-phosphoglucomutase; Beta-PGM; EC 5.4.2.6 from Bacillus subtilis (strain 168)
    30% identity, 88% coverage of query (76.6 bits)

YieH / b3715 6-phosphogluconate phosphatase from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yieH / P31467 6-phosphogluconate phosphatase from Escherichia coli (strain K12) (see 2 papers)
YIEH_ECOLI / P31467 6-phosphogluconate phosphatase; EC 3.1.3.- from Escherichia coli (strain K12) (see 2 papers)
    31% identity, 85% coverage of query (74.7 bits)

SGGP_ARATH / Q9ZVJ5 Haloacid dehalogenase-like hydrolase domain-containing protein Sgpp; Subclass I phosphosugar phosphatase; AtSgpp; EC 3.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9ZVJ5 sugar-phosphatase (EC 3.1.3.23) from Arabidopsis thaliana (see paper)
    31% identity, 87% coverage of query (72.4 bits)

SOQ1_ARATH / Q8VZ10 Protein SUPPRESSOR OF QUENCHING 1, chloroplastic; EC 3.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    35% identity, 89% coverage of query (72.0 bits)

HDHD1_HUMAN / Q08623 Pseudouridine-5'-phosphatase; Haloacid dehalogenase-like hydrolase domain-containing protein 1; Haloacid dehalogenase-like hydrolase domain-containing protein 1A; Protein GS1; Pseudouridine-5'-monophosphatase; 5'-PsiMPase; EC 3.1.3.96 from Homo sapiens (Human) (see paper)
    27% identity, 98% coverage of query (70.9 bits)

ycjU / P77366 β-phosphoglucomutase (EC 5.4.2.6) from Escherichia coli (strain K12) (see 4 papers)
PGMB_ECOLI / P77366 Beta-phosphoglucomutase; Beta-PGM; EC 5.4.2.6 from Escherichia coli (strain K12) (see 4 papers)
P77366 beta-Phosphoglucomutase (EC 5.4.2.6) from Escherichia coli (see paper)
    30% identity, 88% coverage of query (70.9 bits)

4g9bA / P77366 Crystal structure of beta-phosphoglucomutase homolog from escherichia coli, target efi-501172, with bound mg, open lid
    30% identity, 88% coverage of query (70.9 bits)

7ocnA / D0C7J2 Crystal structure of the bifunctional mannitol-1-phosphate dehydrogenase/phosphatase mtld from acinetobacter baumannii (see paper)
    28% identity, 91% coverage of query (70.1 bits)

D0C7J2 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17); mannitol-1-phosphatase (EC 3.1.3.22) from Acinetobacter baumannii (see paper)
    28% identity, 91% coverage of query (70.1 bits)

7ocqA Nadh bound to the dehydrogenase domain of the bifunctional mannitol-1- phosphate dehydrogenase/phosphatase mtld from acinetobacter baumannii
    28% identity, 91% coverage of query (70.1 bits)

7ocpA NADPH bound to the dehydrogenase domain of the bifunctional mannitol- 1-phosphate dehydrogenase/phosphatase mtld from acinetobacter baumannii
    28% identity, 91% coverage of query (70.1 bits)

HxpA / b2293 hexitol phosphatase A (EC 3.1.3.50; EC 3.1.3.22; EC 3.1.3.23; EC 3.1.3.21) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
hxpA / P77625 hexitol phosphatase A (EC 3.1.3.50; EC 3.1.3.22; EC 3.1.3.23; EC 3.1.3.21) from Escherichia coli (strain K12) (see 4 papers)
HXPA_ECOLI / P77625 Hexitol phosphatase A; Mannitol-1-phosphatase; Sorbitol-6-phosphatase; Sugar-phosphatase; EC 3.1.3.22; EC 3.1.3.50; EC 3.1.3.23 from Escherichia coli (strain K12) (see 3 papers)
    30% identity, 95% coverage of query (69.7 bits)

7ocsC Mannitol-1-phosphate bound to the phosphatase domain of the bifunctional mannitol-1-phosphate dehydrogenase/phosphatase mtld-d16a from acinetobacter baumannii
    28% identity, 91% coverage of query (68.9 bits)

7ocqB Nadh bound to the dehydrogenase domain of the bifunctional mannitol-1- phosphate dehydrogenase/phosphatase mtld from acinetobacter baumannii
    27% identity, 91% coverage of query (67.4 bits)

3s6jE / Q88AV7 The crystal structure of a hydrolase from pseudomonas syringae
    27% identity, 80% coverage of query (67.0 bits)

7ocsA Mannitol-1-phosphate bound to the phosphatase domain of the bifunctional mannitol-1-phosphate dehydrogenase/phosphatase mtld-d16a from acinetobacter baumannii
    28% identity, 91% coverage of query (66.6 bits)

P845_THEAC / Q9HJW8 Phosphatase Ta0845; EC 3.1.3.- from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) (see paper)
Q9HJW8 4-nitrophenylphosphatase (EC 3.1.3.41) from Thermoplasma acidophilum (see paper)
    27% identity, 90% coverage of query (66.2 bits)

pgmB / P71447 β-phosphoglucomutase (EC 5.4.2.6) from Lactococcus lactis subsp. lactis (strain IL1403) (see 3 papers)
PGMB_LACLA / P71447 Beta-phosphoglucomutase; Beta-PGM; EC 5.4.2.6 from Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) (see 9 papers)
P71447 beta-Phosphoglucomutase (EC 5.4.2.6) from Lactococcus lactis subsp. lactis (see 2 papers)
    28% identity, 90% coverage of query (65.9 bits)

2wf9A Structure of beta-phosphoglucomutase inhibited with glucose-6- phosphate, and beryllium trifluoride, crystal form 2
    28% identity, 90% coverage of query (65.9 bits)

1o03A Structure of pentavalent phosphorous intermediate of an enzyme catalyzed phosphoryl transfer reaction observed on cocrystallization with glucose 6-phosphate
    28% identity, 90% coverage of query (65.9 bits)

1lvhA The structure of phosphorylated beta-phosphoglucomutase from lactoccocus lactis to 2.3 angstrom resolution
    28% identity, 90% coverage of query (65.9 bits)

5olwA / P71447 5-fluorotryptophan labeled beta-phosphoglucomutase in an open conformation (see paper)
    28% identity, 90% coverage of query (65.5 bits)

6qzgA Beta-glucose 1,6-bisphosphonate bound to wild type beta- phosphoglucomutse in an open conformation.
    28% identity, 90% coverage of query (65.5 bits)

1z4nA Structure of beta-phosphoglucomutase with inhibitor bound alpha- galactose 1-phosphate cocrystallized with fluoride
    28% identity, 90% coverage of query (65.5 bits)

6h91A Phosphorylated beta-phosphoglucomutase from lactococcus lactis in an open conformer to 2.4 a
    28% identity, 90% coverage of query (65.5 bits)

4c4rA Structure of beta-phosphoglucomutase in complex with a phosphonate analogue of beta-glucose-1-phosphate and magnesium trifluoride
    28% identity, 90% coverage of query (65.5 bits)

3zi4A The structure of beta-phosphoglucomutase inhibited with glucose-6- phosphate and scandium tetrafluoride
    28% identity, 90% coverage of query (65.5 bits)

2wf8A Structure of beta-phosphoglucomutase inhibited with glucose-6- phosphate, glucose-1-phosphate and beryllium trifluoride
    28% identity, 90% coverage of query (65.5 bits)

2wf7A Structure of beta-phosphoglucomutase inhibited with glucose-6- phosphonate and aluminium tetrafluoride
    28% identity, 90% coverage of query (65.5 bits)

2wf6A Structure of beta-phosphoglucomutase inhibited with glucose-6- phosphate and aluminium tetrafluoride
    28% identity, 90% coverage of query (65.5 bits)

2wf5A Structure of beta-phosphoglucomutase inhibited with glucose-6- phosphate and trifluoromagnesate
    28% identity, 90% coverage of query (65.5 bits)

4c4sA Structure of beta-phosphoglucomutase in complex with an alpha- fluorophosphonate analogue of beta-glucose-1-phosphate and magnesium trifluoride
    27% identity, 90% coverage of query (65.5 bits)

8q1dA D10n variant of beta-phosphoglucomutase from lactococcus lactis in complex with fructose 1,6-bisphosphate
    27% identity, 90% coverage of query (64.3 bits)

7ocrB NADPH and fructose-6-phosphate bound to the dehydrogenase domain of the bifunctional mannitol-1-phosphate dehydrogenase/phosphatase mtld from acinetobacter baumannii
    27% identity, 91% coverage of query (63.9 bits)

5ok0A Structure of the d10n mutant of beta-phosphoglucomutase from lactococcus lactis trapped with native reaction intermediate beta- glucose 1,6-bisphosphate to 2.2a resolution.
    27% identity, 90% coverage of query (63.9 bits)

5o6rA Structure of beta-phosphoglucomutase d10n mutant in complex with glucose-1-phosphate and aluminium tetrafluoride
    27% identity, 90% coverage of query (63.9 bits)

HaRibK / BAM34419.1 riboflavin kinase from Hyoscyamus albus (see paper)
    27% identity, 86% coverage of query (63.5 bits)

6w04A / C4LXK0 Crystal structure of had hydrolase, family ia, variant 3 from entamoeba histolytica hm-1:imss
    26% identity, 87% coverage of query (61.6 bits)

5o6pA Structure of beta-phosphoglucomutase d10n mutant in complex with glucose-1,6-bisphosphate
    28% identity, 85% coverage of query (61.6 bits)

GPP1_ARATH / F4JTE7 (DL)-glycerol-3-phosphatase 1, mitochondrial; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase; AtGpp1/PyrP3; 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate phosphatase; ARPP phosphatase; Glycerol-1-phosphatase 1; AtGPP1; Haloacid dehalogenase-like hydrolase domain-containing protein GPP1; EC 3.1.3.21; EC 3.1.3.104 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    26% identity, 91% coverage of query (61.2 bits)

4eenA / Q9RTX8 Crystal structure of had family hydrolase dr_1622 from deinococcus radiodurans r1 (target efi-501256) with bound magnesium
    30% identity, 81% coverage of query (60.8 bits)

8q1cA Substrate-free d10n,p146a variant of beta-phosphoglucomutase from lactococcus lactis
    27% identity, 90% coverage of query (60.8 bits)

GPP2_ARATH / Q8VZP1 (DL)-glycerol-3-phosphatase 2; Glycerol-1-phosphatase 2; Haloacid dehalogenase-like hydrolase domain-containing protein GPP2; EC 3.1.3.21 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    27% identity, 91% coverage of query (59.3 bits)

YJM7_SCHPO / O59760 Putative uncharacterized hydrolase C1020.07; EC 3.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    26% identity, 88% coverage of query (58.9 bits)

AT4G21470 / Q84MD8 bifunctional riboflavin kinase / FMN adenylyltransferase (EC 2.7.7.2; EC 2.7.1.26) from Arabidopsis thaliana (see paper)
FHYRK_ARATH / Q84MD8 Bifunctional riboflavin kinase/FMN phosphatase; EC 3.1.3.102; EC 2.7.1.26 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q84MD8 FMN hydrolase (EC 3.1.3.102) from Arabidopsis thaliana (see paper)
    25% identity, 86% coverage of query (58.2 bits)

CBBY_ARATH / Q94K71 CBBY-like protein; AtCbby; EC 3.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    29% identity, 86% coverage of query (56.6 bits)

CAA94730.1 ORF2 from Streptomyces lividans (see 3 papers)
    26% identity, 87% coverage of query (56.6 bits)

4uavA / Q94K71 Crystal structure of cbby (at3g48420) from arabidobsis thaliana (see paper)
    29% identity, 86% coverage of query (56.2 bits)

YKD3A_YEAST / Q86ZR7 Probable pseudouridine-5'-phosphatase YKL033W-A; EC 3.1.3.96 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    26% identity, 91% coverage of query (56.2 bits)

Q83PX1 phosphoglycolate phosphatase (EC 3.1.3.18) from Shigella flexneri (see paper)
    28% identity, 89% coverage of query (56.2 bits)

PPAX_BACSU / Q9JMQ2 Pyrophosphatase PpaX; EC 3.6.1.1 from Bacillus subtilis (strain 168) (see paper)
    24% identity, 90% coverage of query (55.8 bits)

YhfE / b3385 phosphoglycolate phosphatase (EC 3.1.3.18) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gph / P32662 phosphoglycolate phosphatase (EC 3.1.3.18) from Escherichia coli (strain K12) (see 7 papers)
GPH_ECOLI / P32662 Phosphoglycolate phosphatase; PGP; PGPase; EC 3.1.3.18 from Escherichia coli (strain K12) (see 3 papers)
    28% identity, 89% coverage of query (55.1 bits)

2fdrA / A9CJW3 Crystal structure of conserved haloacid dehalogenase-like protein of unknown function atu0790 from agrobacterium tumefaciens str. C58
    26% identity, 87% coverage of query (54.7 bits)

MUPP_PSEAE / Q9HZ62 N-acetylmuramic acid 6-phosphate phosphatase; MurNAc 6-phosphate phosphatase; MurNAc-6P phosphatase; EC 3.1.3.105 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    28% identity, 88% coverage of query (53.9 bits)

1te2A / P77247 Putative phosphatase ynic from escherichia coli k12
    27% identity, 88% coverage of query (53.5 bits)

HxpB / b1727 hexitol phosphatase B (EC 3.1.3.50; EC 3.1.3.22; EC 3.1.3.68) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
hxpB / P77247 hexitol phosphatase B (EC 3.1.3.50; EC 3.1.3.22; EC 3.1.3.68) from Escherichia coli (strain K12) (see 4 papers)
HXPB_ECOLI / P77247 Hexitol phosphatase B; 2-deoxyglucose-6-phosphate phosphatase; Mannitol-1-phosphatase; Sorbitol-6-phosphatase; Sugar-phosphatase; EC 3.1.3.68; EC 3.1.3.22; EC 3.1.3.50; EC 3.1.3.23 from Escherichia coli (strain K12) (see 3 papers)
yniC / RF|NP_416241 phosphatase yniC; EC 3.1.3.- from Escherichia coli K12 (see 6 papers)
    27% identity, 88% coverage of query (53.1 bits)

CBBY_CERSP / P95649 Protein CbbY; RuCbby; EC 3.1.3.- from Cereibacter sphaeroides (Rhodobacter sphaeroides) (see paper)
    26% identity, 88% coverage of query (53.1 bits)

4uasA Crystal structure of cbby from rhodobacter sphaeroides in complex with phosphate
    26% identity, 88% coverage of query (53.1 bits)

HAD1_CRYNH / J9VX38 Probable phosphatase HAD1; EC 3.1.3.- from Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) (see 2 papers)
    25% identity, 84% coverage of query (52.8 bits)

PGMB_MYCTU / P9WKZ7 Beta-phosphoglucomutase; Beta-PGM; EC 5.4.2.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    25% identity, 90% coverage of query (52.4 bits)

4uauA / P95649 Crystal structure of cbby (mutant d10n) from rhodobacter sphaeroides in complex with xylulose-(1,5)bisphosphate, crystal form ii (see paper)
    26% identity, 88% coverage of query (51.6 bits)

GPH_AQUAE / O67359 Phosphoglycolate phosphatase; PGP; PGPase; EC 3.1.3.18 from Aquifex aeolicus (strain VF5)
O67359 phosphoglycolate phosphatase (EC 3.1.3.18) from Aquifex aeolicus (see paper)
    27% identity, 86% coverage of query (49.7 bits)

DOG1_YEAST / P38774 2-deoxyglucose-6-phosphate phosphatase 1; 2-DOG-6-P 1; 2-deoxyglucose-6-phosphatase 1; EC 3.1.3.68 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P38774 2-deoxyglucose-6-phosphatase (EC 3.1.3.68) from Saccharomyces cerevisiae (see paper)
DOG1 / AAC48923.1 2-deoxyglucose-6-phosphate phosphatase from Saccharomyces cerevisiae (see paper)
    27% identity, 90% coverage of query (47.4 bits)

mupP / Q88M11 N-acetyl-β-muramate 6-phosphate phosphatase (EC 3.1.3.105) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
MUPP_PSEPK / Q88M11 N-acetylmuramic acid 6-phosphate phosphatase; MurNAc 6-phosphate phosphatase; MurNAc-6P phosphatase; EC 3.1.3.105 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
Q88M11 N-acetyl-D-muramate 6-phosphate phosphatase (EC 3.1.3.105) from Pseudomonas putida (see 2 papers)
    24% identity, 89% coverage of query (47.0 bits)

RHR2 potential DL-glycerol-3-phosphatase from Candida albicans (see 2 papers)
    28% identity, 87% coverage of query (46.6 bits)

DOG2_YEAST / P38773 2-deoxyglucose-6-phosphate phosphatase 2; 2-DOG-6-P 2; 2-deoxyglucose-6-phosphatase 2; EC 3.1.3.68 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    27% identity, 90% coverage of query (46.2 bits)

4ex6A / B6SEG4 Crystal structure of the alnumycin p phosphatase alnb (see paper)
    27% identity, 88% coverage of query (44.7 bits)

4ex7A Crystal structure of the alnumycin p phosphatase in complex with free phosphate
    27% identity, 88% coverage of query (44.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory