Searching for up to 100 curated homologs for WP_015738359.1 NCBI__GCF_000024605.1:WP_015738359.1 (242 a.a.)
Found high-coverage hits (≥70%) to 9 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
HisE / b2026 putative bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase (EC 3.5.4.19; EC 3.6.1.31) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
hisI / P06989 putative bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase (EC 3.5.4.19; EC 3.6.1.31) from Escherichia coli (strain K12) (see 5 papers)
38% identity, 98% coverage of query (147 bits)
6j2lA / P37793 Crystal structure of bi-functional enzyme (see paper)
37% identity, 98% coverage of query (127 bits)
7bgmA / A0A072U2X9 Crystal structure of mthisn2, a bifunctional enzyme from the histidine biosynthetic pathway (see paper)
33% identity, 98% coverage of query (119 bits)
7bgnA Crystal structure of mthisn2-amp complex, a bifunctional enzyme from the histidine biosynthetic pathway
31% identity, 98% coverage of query (115 bits)
At-IE / O82768 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19; EC 3.6.1.31) from Arabidopsis thaliana (see paper)
HIS2_ARATH / O82768 Histidine biosynthesis bifunctional protein hisIE, chloroplastic; Protein HISTIDINE BIOSYNTHESIS 2; EC 3.5.4.19; EC 3.6.1.31 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
31% identity, 98% coverage of query (113 bits)
6j2lB Crystal structure of bi-functional enzyme
34% identity, 98% coverage of query (100 bits)
A1BPP9 histidinol dehydrogenase (EC 1.1.1.23) from Geotrichum candidum (see paper)
31% identity, 91% coverage of query (78.2 bits)
HIS2_YEAST / P00815 Histidine biosynthesis trifunctional protein; EC 3.5.4.19; EC 3.6.1.31; EC 1.1.1.23 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
30% identity, 94% coverage of query (73.2 bits)
Build an alignment for WP_015738359.1 and 8 homologs with ≥ 30% identity
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HIS2_SCHPO / O59667 Histidine biosynthesis bifunctional protein his7; EC 3.5.4.19; EC 3.6.1.31 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
his7 / GI|3006138 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase His7; EC 3.5.4.19; EC 3.6.1.31 from Schizosaccharomyces pombe (see 2 papers)
29% identity, 86% coverage of query (70.5 bits)
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Lawrence Berkeley National Laboratory