Searching for up to 100 curated homologs for WP_015739079.1 NCBI__GCF_000024605.1:WP_015739079.1 (339 a.a.)
Found high-coverage hits (≥70%) to 93 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6w45A Crystal structure of hao1 in complex with biaryl acid inhibitor - compound 3
36% identity, 86% coverage of query (147 bits)
6a4gA Mandelate oxidase mutant-y128f with the monooxide fmn adduct
38% identity, 88% coverage of query (145 bits)
7m2oA Crystal structure of human glycolate oxidase with inhibitor compound 15
35% identity, 86% coverage of query (144 bits)
2rdtA Crystal structure of human glycolate oxidase (go) in complex with cdst
35% identity, 86% coverage of query (144 bits)
6w44A Crystal structure of hao1 in complex with indazole acid inhibitor - compound 4
35% identity, 86% coverage of query (143 bits)
6a1hA Mandelate oxidase mutant-y128f with 5-deazariboflavin mononucleotide
35% identity, 97% coverage of query (143 bits)
6a0oA Mandelate oxidase mutant-y128f with benzaldehyde
35% identity, 97% coverage of query (143 bits)
6a1rA Mandelate oxidase mutant-y128f with the n5-phenylacetyl-fmn adduct
35% identity, 97% coverage of query (143 bits)
6a3dA The crystal structure of mandelate oxidase y128f with 4-br-2-hydroxy- methylphenylacetate
37% identity, 86% coverage of query (142 bits)
5zztA The crystal structure of mandelate oxidase with 3,3-difluoro-2- hydroxy-3-phenylpropionic acid
35% identity, 97% coverage of query (142 bits)
6w4cA Crystal structure of hao1 in complex with indazole acid inhibitor - compound 5
35% identity, 86% coverage of query (142 bits)
7r4pA / Q9UJM8 Structure of human hydroxyacid oxidase 1 bound with 6-amino-1-benzyl- 5-(methylamino)pyrimidine-2,4(1h,3h)-dione
34% identity, 86% coverage of query (141 bits)
2w0uA Crystal structure of human glycolate oxidase in complex with the inhibitor 5-[(4-chlorophenyl)sulfanyl]- 1,2,3-thiadiazole-4- carboxylate.
35% identity, 86% coverage of query (141 bits)
3sgzA / Q07523 High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl) sulfanyl]-1, 2, 3-thiadiazole. (see paper)
32% identity, 89% coverage of query (140 bits)
6a3tA The crystal structure of mandelate oxidase r163l with 2-hydroxy- phenylacetamide
35% identity, 97% coverage of query (140 bits)
6a01A The crystal structure of mandelate oxidase y128f with 3,3-difluoro-2, 2-dihydroxy-3-phenylpropionic acid
36% identity, 97% coverage of query (140 bits)
6a08A / O52792 The crystal structure of mandelate oxidase with benzoyl-formic acid (see paper)
36% identity, 97% coverage of query (139 bits)
6a1aA Mandelate oxidase mutant-y128f with 4-hydroxymandelic acid
36% identity, 97% coverage of query (139 bits)
7r4oA Structure of human hydroxyacid oxidase 1 bound with 2-((4h-1,2,4- triazol-3-yl)thio)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one
34% identity, 86% coverage of query (139 bits)
6a1nA Mandelate oxidase mutant-y128f with (2r,3s)-3-fluoro-2-hydroxy-3- phenylpropanoic acid
36% identity, 97% coverage of query (139 bits)
6a0gA The crystal structure of mandelate oxidase mutant y128f with b- phenyllactate
36% identity, 97% coverage of query (139 bits)
6a36A Mandelate oxidase mutant-y128f with the 3-fluoropyruvic acid fmn adduct
36% identity, 97% coverage of query (139 bits)
6a0bA The crystal structure of mandelate oxidase mutant y128f with (r)-3,3, 3-trifluoro-2-hydroxy-propionic acid
36% identity, 97% coverage of query (139 bits)
5zzxA The crystal structure of mandelate oxidase mutant y128f with (r)- mandelic acid
36% identity, 97% coverage of query (139 bits)
6a23A Mandelate oxidase mutant-y128f with the n5-benzyl-fmn adduct
36% identity, 97% coverage of query (139 bits)
6a4hA Mandelate oxidase mutant-y128f with the peroxide fmn adduct
37% identity, 86% coverage of query (139 bits)
7bsrA Mandelate oxidase with the 2-hydroxy-3-oxosuccinic acid
36% identity, 96% coverage of query (139 bits)
6a39A The crystal structure of mandelate oxidase y128f with c4a-malic acid- monooxide-fmn adduct
36% identity, 96% coverage of query (139 bits)
6a0mA Mandelate oxidase mutant-y128f with 2-phenylacetic acid
36% identity, 96% coverage of query (139 bits)
6a21A Mandelate oxidase mutant-y128f with the n5-malonyl-fmn adduct
36% identity, 97% coverage of query (139 bits)
6a1bA Mandelate oxidase mutant-y128f with 3,3,3-trifluoro-2,2- dihydroxypropanoic acid
36% identity, 97% coverage of query (139 bits)
6a11A Mandelate oxidase mutant-y128f with phenylpyruvic acid
36% identity, 97% coverage of query (139 bits)
6a1wA Mandelate oxidase with the enoyl fmn epoxide adduct
36% identity, 97% coverage of query (138 bits)
6a00A The crystal structure of mandelate oxidase with (s)-2-phenylpropionate
36% identity, 97% coverage of query (138 bits)
5zzrA The crystal structure of mandelate oxidase with (s)-mandelic acid
36% identity, 97% coverage of query (138 bits)
5qihA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z2697514548
34% identity, 86% coverage of query (138 bits)
5qidA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z1787627869
34% identity, 86% coverage of query (138 bits)
5qicA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z30620520
34% identity, 86% coverage of query (138 bits)
5qibA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with fmopl000388a
34% identity, 86% coverage of query (138 bits)
HAOX1_MOUSE / Q9WU19 2-Hydroxyacid oxidase 1; HAOX1; Glycolate oxidase; GOX; Glyoxylate oxidase; EC 1.1.3.15; EC 1.2.3.5 from Mus musculus (Mouse) (see paper)
Q9WU19 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Mus musculus (see 3 papers)
31% identity, 89% coverage of query (136 bits)
HAOX2_MOUSE / Q9NYQ2 2-Hydroxyacid oxidase 2; HAOX2; (S)-2-hydroxy-acid oxidase, peroxisomal; Medium chain alpha-hydroxy acid oxidase; Medium-chain L-2-hydroxy acid oxidase; EC 1.1.3.15 from Mus musculus (Mouse) (see paper)
Q9NYQ2 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Mus musculus (see paper)
32% identity, 89% coverage of query (136 bits)
1al8A Three-dimensional structure of glycolate oxidase with bound active- site inhibitors
32% identity, 84% coverage of query (136 bits)
7r4nA Structure of human hydroxyacid oxidase 1 bound with 5-bromo-n-methyl- 1h-indazole-3-carboxamide
33% identity, 86% coverage of query (136 bits)
5qieA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z2856434894
33% identity, 86% coverage of query (136 bits)
HAOX2_RAT / Q07523 2-Hydroxyacid oxidase 2; HAOX2; (S)-2-hydroxy-acid oxidase, peroxisomal; Long chain alpha-hydroxy acid oxidase; Long-chain L-2-hydroxy acid oxidase; LCHAO; EC 1.1.3.15 from Rattus norvegicus (Rat) (see 5 papers)
31% identity, 89% coverage of query (135 bits)
5qigA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z1407672867
32% identity, 86% coverage of query (134 bits)
5qifA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z31792168
32% identity, 86% coverage of query (134 bits)
2rdwA Crystal structure of human glycolate oxidase in complex with sulfate
32% identity, 86% coverage of query (134 bits)
2rduA Crystal structure of human glycolate oxidase in complex with glyoxylate
32% identity, 86% coverage of query (134 bits)
6gmbA / Q9UJM8 Structure of human hydroxyacid oxidase 1 bound with fmn and glycolate
32% identity, 86% coverage of query (133 bits)
HAOX1_HUMAN / Q9UJM8 2-Hydroxyacid oxidase 1; HAOX1; Glycolate oxidase; GO; GOX; Glyoxylate oxidase; EC 1.1.3.15; EC 1.2.3.5 from Homo sapiens (Human) (see 4 papers)
Q9UJM8 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Homo sapiens (see 2 papers)
32% identity, 86% coverage of query (133 bits)
6gmcA 1.2 a resolution structure of human hydroxyacid oxidase 1 bound with fmn and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole
32% identity, 86% coverage of query (133 bits)
HAOX1_ARATH / Q9LJH5 Peroxisomal (S)-2-hydroxyacid oxidase GLO4; Glycolate oxidase 4; AtGLO4; GOX 4; lHAOX1; EC 1.1.3.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9LJH5 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Arabidopsis thaliana (see paper)
32% identity, 89% coverage of query (132 bits)
5zzqA / O52792 The crystal structure of mandelate oxidase with (s)-4-hydroxymandelic acid (see paper)
34% identity, 97% coverage of query (132 bits)
HMO_AMYOR / O52792 4-hydroxymandelate oxidase; EC 1.1.3.46 from Amycolatopsis orientalis (Nocardia orientalis) (see 3 papers)
O52792 4-hydroxymandelate oxidase (EC 1.1.3.46) from Amycolatopsis orientalis (see 2 papers)
34% identity, 97% coverage of query (132 bits)
Build an alignment for WP_015739079.1 and 55 homologs with ≥ 30% identity
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LOX_LACJE / A0A5N1I561 L-lactate oxidase; LOX; (S)-2-hydroxy-acid oxidase; EC 1.1.3.-; EC 1.1.3.15 from Lactobacillus jensenii (see paper)
29% identity, 87% coverage of query (132 bits)
1al7A Three-dimensional structures of glycolate oxidase with bound active- site inhibitors
31% identity, 84% coverage of query (132 bits)
6a24A The crystal structure of mandelate oxidase with 3-fluoropyruvate
34% identity, 97% coverage of query (132 bits)
LOX_ALIDK / F4G5A4 L-lactate oxidase; LOX; Glycolate oxidase; EC 1.1.3.-; EC 1.1.3.15 from Alicycliphilus denitrificans (strain DSM 14773 / CIP 107495 / K601) (see paper)
32% identity, 89% coverage of query (131 bits)
HAOX2_ARATH / Q24JJ8 Peroxisomal (S)-2-hydroxyacid oxidase GLO3; Glycolate oxidase 3; AtGLO3; GOX 3; Short chain alpha-hydroxy acid oxidase GLO3; lHAOX2; EC 1.1.3.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q24JJ8 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Arabidopsis thaliana (see paper)
32% identity, 89% coverage of query (130 bits)
Q8H3I4 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Oryza sativa Japonica Group (see paper)
32% identity, 86% coverage of query (129 bits)
GOX_SPIOL / P05414 Glycolate oxidase; GAO; GOX; Short chain alpha-hydroxy acid oxidase; EC 1.1.3.15 from Spinacia oleracea (Spinach) (see 5 papers)
P05414 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Spinacia oleracea (see paper)
30% identity, 84% coverage of query (129 bits)
B9S0Y9 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Ricinus communis (see paper)
27% identity, 98% coverage of query (129 bits)
5zbmB / E1AXT8 Structure of glycolate oxidase containing fmn from nicotiana benthamiana (see paper)
30% identity, 83% coverage of query (128 bits)
QULF_PENCI / P0DUR7 FMN-dependent alpha-hydroxy acid dehydrogenase qulF; Quinolactacin A2 biosynthesis cluster protein F; EC 1.13.12.- from Penicillium citrinum (see paper)
28% identity, 89% coverage of query (127 bits)
GLO1_ORYSJ / Q10CE4 Glycolate oxidase 1; GOX 1; OsGLO1; Peroxisomal (S)-2-hydroxy-acid oxidase GLO1; Short chain alpha-hydroxy acid oxidase GLO1; EC 1.1.3.15 from Oryza sativa subsp. japonica (Rice) (see 4 papers)
Q10CE4 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Oryza sativa Japonica Group (see paper)
31% identity, 85% coverage of query (127 bits)
LOX_LYSSC / B1HZY7 L-lactate oxidase; LOX; (S)-2-hydroxy-acid oxidase; EC 1.1.3.-; EC 1.1.3.15 from Lysinibacillus sphaericus (strain C3-41) (see paper)
29% identity, 91% coverage of query (127 bits)
E1AXT8 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Nicotiana benthamiana (see 2 papers)
30% identity, 83% coverage of query (126 bits)
GLO1_ARATH / Q9LRR9 Glycolate oxidase 1; AtGLO1; GOX1; (S)-2-hydroxy-acid oxidase GLO1; Short chain alpha-hydroxy acid oxidase GLO1; EC 1.1.3.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9LRR9 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Arabidopsis thaliana (see paper)
28% identity, 85% coverage of query (125 bits)
GLO2_ARATH / Q9LRS0 Glycolate oxidase 2; AtGLO2; GOX2; (S)-2-hydroxy-acid oxidase GLO2; Short chain alpha-hydroxy acid oxidase GLO2; EC 1.1.3.15 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
28% identity, 85% coverage of query (124 bits)
GOX1_MAIZE / A0A3L6E0R4 Glycolate oxidase 1; GOX; EC 1.1.3.15 from Zea mays (Maize) (see 2 papers)
28% identity, 84% coverage of query (119 bits)
6dviD / P21795 Wild-type lactate monooxygenase from mycobacterium smegmatis (see paper)
33% identity, 89% coverage of query (117 bits)
2nliB / Q44467 Crystal structure of the complex between l-lactate oxidase and a substrate analogue at 1.59 angstrom resolution (see paper)
29% identity, 93% coverage of query (117 bits)
2j6xH / Q44467 The crystal structure of lactate oxidase (see paper)
29% identity, 93% coverage of query (116 bits)
LOX_LACRM / C2K1F0 L-lactate oxidase; LOX; EC 1.1.3.- from Lacticaseibacillus rhamnosus (strain LMS2-1) (see paper)
31% identity, 86% coverage of query (115 bits)
8ufyB High resolution structure of a. Viridans lactate oxidase
29% identity, 93% coverage of query (115 bits)
2j6xD The crystal structure of lactate oxidase
28% identity, 93% coverage of query (115 bits)
lctO / D4YFM2 lactate oxidase monomer (EC 1.1.3.2) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see 29 papers)
D4YFM2 L-lactate oxidase (EC 1.1.3.2) from Aerococcus viridans (see 2 papers)
27% identity, 97% coverage of query (113 bits)
RF|XP_001522874.1 putative cytochrome b2, mitochondrial precursor [Cryptococcus neoformans] from Magnaporthe grisea 70-15 (see paper)
32% identity, 86% coverage of query (111 bits)
6r9vA / E0NE46 Crystal structure of pediococcus acidilactici lactate oxidase a94g mutant (see paper)
29% identity, 88% coverage of query (111 bits)
2e77A Crystal structure of l-lactate oxidase with pyruvate complex
28% identity, 93% coverage of query (111 bits)
4rjeA Aerococcus viridans l-lactate oxidase mutant
30% identity, 93% coverage of query (111 bits)
LOX_AERVM / Q44467 L-lactate oxidase; LOD; LOX; Lactate oxidase; EC 1.1.3.- from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see 11 papers)
Q44467 L-lactate dehydrogenase (EC 1.1.1.27); L-lactate oxidase (EC 1.1.3.2) from Aerococcus viridans (see 18 papers)
2du2A / Q44467 Crystal structure analysis of the l-lactate oxidase (see paper)
27% identity, 97% coverage of query (110 bits)
A0A0P0KG57 4-hydroxymandelate oxidase (EC 1.1.3.46) from Streptomyces sp. (see paper)
32% identity, 85% coverage of query (109 bits)
YKN3_SCHPO / Q9HDX2 FMN-dependent alpha-hydroxy acid dehydrogenase PB1A11.03; EC 1.13.12.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
29% identity, 87% coverage of query (109 bits)
FUB9_GIBF5 / S0DRI9 Oxidase FUB9; Fusaric acid biosynthesis protein 9; EC 1.-.-.- from Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi) (see 8 papers)
26% identity, 88% coverage of query (101 bits)
LOX_STRIN / O33655 L-lactate oxidase; LOX; EC 1.1.3.- from Streptococcus iniae (Streptococcus shiloi) (see paper)
O33655 L-lactate oxidase (EC 1.1.3.2) from Streptococcus iniae (see paper)
29% identity, 88% coverage of query (99.8 bits)
A9QH69 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15); L-lactate oxidase (EC 1.1.3.2) from Streptococcus iniae (see paper)
29% identity, 88% coverage of query (99.4 bits)
FUB9_GIBM7 / W7NCP1 Oxidase FUB9; Fusaric acid biosynthesis protein 9; EC 1.-.-.- from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) (see 9 papers)
26% identity, 88% coverage of query (97.1 bits)
FUB9_FUSO4 / A0A0D2YG00 Oxidase FUB9; Fusaric acid biosynthesis protein 9; EC 1.-.-.- from Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) (Fusarium vascular wilt of tomato) (see 8 papers)
26% identity, 88% coverage of query (95.9 bits)
A9QH71 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Streptococcus iniae (see paper)
28% identity, 88% coverage of query (90.9 bits)
CYBL_RHOGR / P32953 (S)-mandelate dehydrogenase, mitochondrial; Flavocytochrome b; L(+)-mandelate dehydrogenase; L-MDH; EC 1.1.99.31 from Rhodotorula graminis (Yeast) (see 2 papers)
CAA04758.1 L-mandelate dehydrogenase from Rhodotorula graminis (see paper)
27% identity, 89% coverage of query (84.7 bits)
fni / Q58272 isopentenyl-diphosphate Δ-isomerase monomer (EC 5.3.3.2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
IDI2_METJA / Q58272 Isopentenyl-diphosphate delta-isomerase; IPP isomerase; Isopentenyl diphosphate:dimethylallyl diphosphate isomerase; Isopentenyl pyrophosphate isomerase; Type 2 isopentenyl diphosphate isomerase; IDI-2; EC 5.3.3.2 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
25% identity, 77% coverage of query (54.7 bits)
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Lawrence Berkeley National Laboratory