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Searching for up to 100 curated homologs for WP_015739145.1 NCBI__GCF_000024605.1:WP_015739145.1 (367 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q81P63 prephenate dehydrogenase (EC 1.3.1.12) from Bacillus anthracis (see paper)
    39% identity, 96% coverage of query (252 bits)

5uyyA / Q81P63 Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with l-tyrosine (see paper)
    39% identity, 96% coverage of query (251 bits)

6u60B Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with NAD and l-tyrosine
    39% identity, 95% coverage of query (251 bits)

Q8DUW0 prephenate dehydrogenase (EC 1.3.1.12) from Streptococcus mutans (see paper)
    34% identity, 96% coverage of query (199 bits)

3gggD / O67636 The crystal structure of a. Aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+ (see paper)
    36% identity, 77% coverage of query (175 bits)

O67636 prephenate dehydrogenase (EC 1.3.1.12) from Aquifex aeolicus (see paper)
    36% identity, 77% coverage of query (175 bits)

3ggoA Crystal structure of prephenate dehydrogenase from a. Aeolicus with hpp and nadh
    36% identity, 77% coverage of query (175 bits)

3ggpA Crystal structure of prephenate dehydrogenase from a. Aeolicus in complex with hydroxyphenyl propionate and NAD+
    36% identity, 77% coverage of query (175 bits)

4wjiA / Q92MG1 Crystal structure of cyclohexadienyl dehydrogenase from sinorhizobium meliloti in complex with NADP and tyrosine
    37% identity, 76% coverage of query (171 bits)

3b1fA / Q8DUW0 Crystal structure of prephenate dehydrogenase from streptococcus mutans (see paper)
    36% identity, 76% coverage of query (170 bits)

tyrAa / P73906 arogenate dehydrogenase monomer (EC 1.3.1.78) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
P73906 arogenate dehydrogenase (NADP+) (EC 1.3.1.78) from Synechocystis sp. PCC 6803 (see paper)
2f1kA / P73906 Crystal structure of synechocystis arogenate dehydrogenase (see paper)
    38% identity, 70% coverage of query (155 bits)

TYRC_ZYMMO / Q04983 Cyclohexadienyl dehydrogenase; Arogenate dehydrogenase; ADH; Prephenate dehydrogenase; PDH; EC 1.3.1.43; EC 1.3.1.12 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
    32% identity, 78% coverage of query (149 bits)

Build an alignment

Build an alignment for WP_015739145.1 and 12 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

novF / Q9L9G2 prephenate dehydrogenase (EC 1.3.1.12) from Streptomyces niveus (see paper)
    28% identity, 95% coverage of query (72.8 bits)

P43902 prephenate dehydrogenase (EC 1.3.1.12) from Haemophilus influenzae (see paper)
    23% identity, 82% coverage of query (53.1 bits)

2pv7B / P43902 Crystal structure of chorismate mutase / prephenate dehydrogenase (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution (see paper)
    24% identity, 80% coverage of query (51.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory