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Searching for up to 100 curated homologs for WP_015739869.1 NCBI__GCF_000024605.1:WP_015739869.1 (348 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4grsA / Q8U0A9,Q9WYH8 Crystal structure of a chimeric dah7ps (see paper)
    56% identity, 94% coverage of query (370 bits)

Q9WYH8 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Thermotoga maritima (see paper)
3pg9A / Q9WYH8 Thermotoga maritima dah7p synthase in complex with inhibitor (see paper)
    54% identity, 96% coverage of query (365 bits)

1rzmA Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahps) from thermotoga maritima complexed with cd2+, pep and e4p
    54% identity, 96% coverage of query (365 bits)

4c1kA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    59% identity, 73% coverage of query (310 bits)

1zcoB Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    59% identity, 72% coverage of query (309 bits)

1zcoA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    59% identity, 72% coverage of query (309 bits)

5j6fA / L8A208 Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
    57% identity, 74% coverage of query (303 bits)

3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate
    55% identity, 72% coverage of query (292 bits)

3nvtA / Q8Y6T2 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
    55% identity, 72% coverage of query (291 bits)

1vs1D / Q9YEJ7 Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahp synthase) from aeropyrum pernix in complex with mn2+ and pep
    65% identity, 74% coverage of query (282 bits)

Q9YEJ7 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Aeropyrum pernix (see paper)
    65% identity, 74% coverage of query (282 bits)

P39912 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54); chorismate mutase (EC 5.4.99.5) from Bacillus subtilis (see paper)
    54% identity, 74% coverage of query (280 bits)

P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168)
    54% identity, 74% coverage of query (280 bits)

ccmA / BAA05463.1 32.4kD protein from Synechocystis sp. PCC 6803 (see paper)
    51% identity, 84% coverage of query (278 bits)

A0A482F152 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from uncultured bacterium (see paper)
    51% identity, 75% coverage of query (241 bits)

Build an alignment

Build an alignment for WP_015739869.1 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Q9ZE84 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Rickettsia prowazekii (see paper)
    26% identity, 71% coverage of query (89.4 bits)

Q9ZFK4 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Pseudomonas aeruginosa (see paper)
    25% identity, 71% coverage of query (83.2 bits)

Q9Z7I4 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Chlamydia pneumoniae (see paper)
    30% identity, 70% coverage of query (82.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory