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Searching for up to 100 curated homologs for WP_015928039.1 NCBI__GCF_000022085.1:WP_015928039.1 (253 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4xgnA / Q2T0K5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase in complex with NAD from burkholderia thailandensis
    59% identity, 100% coverage of query (277 bits)

fadB2x / Q88KS5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.178) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
    58% identity, 100% coverage of query (266 bits)

4o5oB / A0A0H3G6B0 X-ray crystal structure of a 3-hydroxyacyl-coa dehydrogenase from brucella suis
    56% identity, 100% coverage of query (263 bits)

1u7tA Crystal structure of abad/hsd10 with a bound inhibitor
    51% identity, 98% coverage of query (246 bits)

O70351 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Rattus norvegicus (Rat)
    51% identity, 98% coverage of query (245 bits)

1e3wD / O70351 Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and 3-keto butyrate (see paper)
    51% identity, 98% coverage of query (244 bits)

HSD17B10 / Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.35; EC 1.1.1.178; EC 1.1.1.239) from Homo sapiens (see 3 papers)
HCD2_HUMAN / Q99714 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Homo sapiens (Human) (see 22 papers)
Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC 1.1.1.178) from Homo sapiens (see 2 papers)
    51% identity, 98% coverage of query (244 bits)

8cbkC / Q99714 Structure of human mitochondrial rnase p in complex with mitochondrial pre-tRNA-his(5,ser) (see paper)
    51% identity, 98% coverage of query (244 bits)

HCD2_DROME / O18404 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxyacyl-CoA dehydrogenase type II; Hydroxysteroid dehydrogenase; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Scully protein; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.62; EC 1.1.1.-; EC 1.1.1.53 from Drosophila melanogaster (Fruit fly) (see 7 papers)
    51% identity, 98% coverage of query (241 bits)

HCD2_MOUSE / O08756 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Mus musculus (Mouse) (see paper)
    50% identity, 98% coverage of query (240 bits)

1uayA / Q7SIA1 Crystal structure of type ii 3-hydroxyacyl-coa dehydrogenase from thermus thermophilus hb8
    56% identity, 98% coverage of query (238 bits)

6ujkA / P9WGQ7 Crystal structure of a probable short-chain type dehydrogenase/reductase (rv1144) from mycobacterium tuberculosis with bound NAD
    51% identity, 100% coverage of query (232 bits)

1e6wC Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and estradiol
    49% identity, 98% coverage of query (232 bits)

7n09A / F1L0H2 Structural basis for branched substrate selectivity in a ketoreductase from ascaris suum
    47% identity, 99% coverage of query (211 bits)

3ppiA / A0A0H3A4S5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from mycobacterium avium (see paper)
    45% identity, 100% coverage of query (195 bits)

IDOLDH / G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see paper)
IDLDH_IPSPI / G5DGA8 Ipsdienol dehydrogenase; EC 1.1.1.386 from Ips pini (Pine engraver beetle) (see paper)
G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see 2 papers)
    36% identity, 98% coverage of query (151 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    34% identity, 98% coverage of query (137 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    34% identity, 98% coverage of query (134 bits)

4cqlI / Q92506 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD (see paper)
    36% identity, 96% coverage of query (122 bits)

Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
    34% identity, 96% coverage of query (119 bits)

HSD17B8 / Q92506 estradiol 17β-dehydrogenase 8 (EC 1.1.1.100) from Homo sapiens (see 4 papers)
DHB8_HUMAN / Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; HSD17B8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Protein Ke6; Ke6; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Homo sapiens (Human) (see 5 papers)
Q92506 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Homo sapiens (see paper)
    35% identity, 96% coverage of query (119 bits)

7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
    35% identity, 98% coverage of query (117 bits)

4cqmA Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP
    35% identity, 96% coverage of query (117 bits)

SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) from Shewanella oneidensis MR-1
    36% identity, 99% coverage of query (116 bits)

BWI76_RS23705 2-deoxy-D-ribonyl-CoA 3-dehydrogenase from Klebsiella michiganensis M5al
    35% identity, 98% coverage of query (114 bits)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    32% identity, 98% coverage of query (114 bits)

phaB / Q3IZW0 (R)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.36) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see 3 papers)
    36% identity, 94% coverage of query (112 bits)

PHAB_SYNY3 / P73826 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    33% identity, 94% coverage of query (110 bits)

3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
    33% identity, 99% coverage of query (110 bits)

6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
    34% identity, 99% coverage of query (110 bits)

fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
    32% identity, 97% coverage of query (110 bits)

Ira5 / Q1NEI6 L-2-keto-3-deoxyrhamnonate 4-dehydrogenase subunit (EC 1.1.1.401) from Sphingomonas sp. (strain SKA58) (see paper)
KDRDH_SPHSS / Q1NEI6 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD(+)); 2-keto-3-deoxy-L-rhamnonate dehydrogenase; KDRDH; L-KDR dehydrogenase; L-KDR 4-dehydrogenase; EC 1.1.1.401 from Sphingomonas sp. (strain SKA58) (see paper)
Q1NEI6 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+) (EC 1.1.1.401) from Sphingomonas sp. (see paper)
    40% identity, 90% coverage of query (110 bits)

DHB8_RAT / Q6MGB5 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Rattus norvegicus (Rat) (see paper)
    35% identity, 99% coverage of query (110 bits)

4cqmF / Q8N4T8 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP (see paper)
    32% identity, 95% coverage of query (110 bits)

CBR4 / Q8N4T8 carbonyl reductase family member 4 (EC 1.1.1.100) from Homo sapiens (see 2 papers)
CBR4_HUMAN / Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; Carbonyl reductase family member 4; CBR4; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; EC 1.1.1.100; EC 1.6.5.10 from Homo sapiens (Human) (see 3 papers)
    32% identity, 95% coverage of query (110 bits)

phaB / BAC45231.1 3-keto-acyl-CoA reductase from Bacillus sp. INT005 (see paper)
    33% identity, 99% coverage of query (109 bits)

5h5xC / Q9KYM4 Crystal structure of nadh bound carbonyl reductase from streptomyces coelicolor
    37% identity, 98% coverage of query (108 bits)

9clyB / Q8E0R2 Crystal structure of the 3-ketoacyl-(acyl-carrier-protein) reductase, cylg, from streptococcus agalactiae 2603v/r
    31% identity, 95% coverage of query (108 bits)

6d9yB / B2JLJ0 Crystal structure of a short chain dehydrogenase/reductase sdr from burkholderia phymatum with partially occupied NAD
    33% identity, 97% coverage of query (107 bits)

phbB / P23238 acetoacetyl-CoA reductase subunit (EC 1.1.1.36) from Shinella zoogloeoides (see 2 papers)
PHAB_SHIZO / P23238 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Shinella zoogloeoides (Crabtreella saccharophila) (see paper)
    35% identity, 94% coverage of query (107 bits)

baiA3 / P07914 3α-hydroxysteroyl-CoA 3-dehydrogenase monomer (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 8 papers)
BAIA1_CLOSV / P07914 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 1/3; 3alpha-hydroxysteroid dehydrogenase 1/3; 3alpha-HSDH 1/3; Bile acid-inducible protein BaiA1; Bile acid-inducible protein BaiA3; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
    31% identity, 98% coverage of query (107 bits)

G3XRE5 gluconate 5-dehydrogenase (EC 1.1.1.69) from Aspergillus niger (see paper)
    33% identity, 97% coverage of query (107 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    31% identity, 96% coverage of query (107 bits)

phbB / AAA90983.1 acetoacetyl CoA reductase from Sinorhizobium meliloti (see 2 papers)
    37% identity, 94% coverage of query (106 bits)

FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
    33% identity, 99% coverage of query (106 bits)

6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
    34% identity, 88% coverage of query (106 bits)

BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
    33% identity, 97% coverage of query (105 bits)

1nffA / P9WGT1 Crystal structure of rv2002 gene product from mycobacterium tuberculosis (see paper)
    33% identity, 91% coverage of query (105 bits)

1nfqA Rv2002 gene product from mycobacterium tuberculosis
    33% identity, 91% coverage of query (105 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    33% identity, 99% coverage of query (104 bits)

badH / O07457 BadH from Rhodopseudomonas palustris (see paper)
    34% identity, 99% coverage of query (104 bits)

1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
    33% identity, 98% coverage of query (104 bits)

BN592_00769 / R7B6R4 3α-hydroxysteroid dehydrogenase (EC 1.1.1.52) from Eggerthella sp. CAG:298 (see paper)
R7B6R4 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213) from Eggerthella sp. CAG:298 (see paper)
    32% identity, 98% coverage of query (103 bits)

SDH_CERSP / Q59787 Sorbitol dehydrogenase; SDH; Galactitol 2-dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; EC 1.1.1.-; EC 1.1.1.16; EC 1.1.1.14 from Cereibacter sphaeroides (Rhodobacter sphaeroides) (see 2 papers)
polS / GI|2338763 L-iditol 2-dehydrogenase; EC 1.1.1.14 from Rhodobacter sphaeroides (see 2 papers)
    36% identity, 88% coverage of query (103 bits)

7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
    33% identity, 96% coverage of query (103 bits)

HSD_MYCTU / P9WGT1 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; NADH-dependent 3alpha, 20beta-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
GI|3261591 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis H37Rv (see paper)
    34% identity, 90% coverage of query (103 bits)

C7RM91 acetoacetyl-CoA reductase (EC 1.1.1.36) from Candidatus Accumulibacter phosphatis (see 2 papers)
    36% identity, 85% coverage of query (103 bits)

3ak4A / G1K3P5 Crystal structure of nadh-dependent quinuclidinone reductase from agrobacterium tumefaciens
    35% identity, 99% coverage of query (103 bits)

4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
    36% identity, 95% coverage of query (103 bits)

budC / H9XP47 meso-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) from Serratia marcescens (see paper)
MBDH_SERMA / H9XP47 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens (see 3 papers)
    31% identity, 97% coverage of query (103 bits)

A0A5P1R8U8 acetoacetyl-CoA reductase (subunit 2/2) (EC 1.1.1.36) from Neptunomonas concharum (see paper)
    31% identity, 77% coverage of query (102 bits)

A0A5P1RES5 acetoacetyl-CoA reductase (subunit 1/2) (EC 1.1.1.36) from Neptunomonas concharum (see paper)
    31% identity, 96% coverage of query (102 bits)

Build an alignment

Build an alignment for WP_015928039.1 and 62 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

baiA2 / P19337 3α-hydroxysteroid dehydrogenase 2 (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 4 papers)
BAIA2_CLOSV / P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2; 3alpha-hydroxysteroid dehydrogenase 2; 3alpha-HSDH 2; Bile acid-inducible protein BaiA2; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase (EC 1.1.1.395) from [Clostridium] scindens (see paper)
    29% identity, 98% coverage of query (102 bits)

1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
    32% identity, 98% coverage of query (102 bits)

4is3C / P19337 Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (baia2) associated with secondary bile acid synthesis from clostridium scindens vpi12708 in complex with a putative NAD(+)-oh- adduct at 2.0 a resolution
    29% identity, 98% coverage of query (101 bits)

YfeF / b2426 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
ucpA / P37440 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli (strain K12) (see 6 papers)
    35% identity, 97% coverage of query (101 bits)

6qheA / A0A545BBS8 Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
    35% identity, 96% coverage of query (101 bits)

FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    32% identity, 99% coverage of query (101 bits)

4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
    33% identity, 96% coverage of query (101 bits)

4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
    33% identity, 99% coverage of query (101 bits)

6vspB / H9XP47 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a (see paper)
    32% identity, 94% coverage of query (100 bits)

Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
    28% identity, 95% coverage of query (100 bits)

DHB8_MOUSE / P50171 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Protein Ke6; Ke-6; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Mus musculus (Mouse) (see 2 papers)
    34% identity, 99% coverage of query (100 bits)

6xewA Structure of serratia marcescens 2,3-butanediol dehydrogenase
    32% identity, 94% coverage of query (100 bits)

6vspA Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a
    32% identity, 94% coverage of query (100 bits)

8y83A / A0A562MSV3 Crystal structure of a ketoreductase from sphingobacterium siyangense sy1 with co-enzyme
    33% identity, 94% coverage of query (100 bits)

1iy8A / Q9LBG2 Crystal structure of levodione reductase (see paper)
    35% identity, 94% coverage of query (99.8 bits)

Q9LBG2 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum)
    35% identity, 94% coverage of query (99.8 bits)

7v1qA / U2RWV7 Leifsonia alcohol dehydrogenases lnadh (see paper)
    36% identity, 97% coverage of query (99.4 bits)

5ts3A / C0RKU3 Crystal structure of a 3-oxoacyl-[acyl-carrier protein] reductase with bound NAD from brucella melitensis
    32% identity, 96% coverage of query (99.0 bits)

5t5qC / Q2YL80 Crystal structure of short-chain dehydrogenase/reductase sdr:glucose/ribitol dehydrogenase from brucella melitensis
    33% identity, 96% coverage of query (99.0 bits)

4wecA / A0QVJ7 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
    32% identity, 98% coverage of query (97.1 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    30% identity, 96% coverage of query (95.5 bits)

1edoA / Q93X62 The x-ray structure of beta-keto acyl carrier protein reductase from brassica napus complexed with NADP+ (see paper)
    32% identity, 95% coverage of query (95.5 bits)

3vzsB / P14697 Crystal structure of phab from ralstonia eutropha in complex with acetoacetyl-coa and NADP (see paper)
    31% identity, 96% coverage of query (95.1 bits)

5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    29% identity, 99% coverage of query (95.1 bits)

phbB / D3UAK7 hydroxyvaleryl-CoA reductase (EC 1.1.1.36) from Cupriavidus necator (see 2 papers)
PHAB_CUPNH / P14697 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see 4 papers)
P14697 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); acetoacetyl-CoA reductase (EC 1.1.1.36) from Cupriavidus necator (see 3 papers)
    31% identity, 96% coverage of query (95.1 bits)

3s55D / B1MLR7 Crystal structure of a putative short-chain dehydrogenase/reductase from mycobacterium abscessus bound to NAD (see paper)
    31% identity, 96% coverage of query (95.1 bits)

fabG1 / P9WGT2 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see paper)
MABA_MYCTU / P9WGT3 3-oxoacyl-[acyl-carrier-protein] reductase MabA; 3-ketoacyl reductase; 3-ketoacyl-acyl carrier protein reductase; Acetoacetyl-CoA reductase; Beta-ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; Mycolic acid biosynthesis A; EC 1.1.1.100; EC 1.1.1.36 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 10 papers)
P9WGT3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (see paper)
    30% identity, 96% coverage of query (94.0 bits)

7emgB Carbonyl reductase variant 4 (r123c/l209p/f183y/v61k) from serratia marcescens complexed with NADP+ (see paper)
    30% identity, 98% coverage of query (94.0 bits)

5ovlA Crystal structure of maba bound to NADP+ from m. Smegmatis
    31% identity, 96% coverage of query (93.2 bits)

budC / Q48436 acetoin reductase subunit (EC 1.1.1.304) from Klebsiella pneumoniae (see 4 papers)
BUDC_KLEPN / Q48436 Diacetyl reductase [(S)-acetoin forming]; Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase; EC 1.1.1.304 from Klebsiella pneumoniae (see paper)
Q48436 diacetyl reductase [(S)-acetoin forming] (EC 1.1.1.304); (S,S)-butanediol dehydrogenase (EC 1.1.1.76) from Klebsiella pneumoniae (see 2 papers)
budC / GB|AAC78679.1 diacetyl reductase ((S)-acetoin forming); EC 1.1.1.304 from Klebsiella pneumoniae (see 3 papers)
    33% identity, 95% coverage of query (93.2 bits)

5ovkA / P71534 Crystal structure maba bound to NADPH from m. Smegmatis (see paper)
    31% identity, 96% coverage of query (93.2 bits)

MABA_MYCS2 / P71534 3-oxoacyl-[acyl-carrier-protein] reductase MabA; 3-ketoacyl-acyl carrier protein reductase; Acetoacetyl-CoA reductase; Beta-ketoacyl-ACP reductase; Beta-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100; EC 1.1.1.36 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
P71534 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycolicibacterium smegmatis (see paper)
    31% identity, 96% coverage of query (93.2 bits)

HPGD / P15428 15-hydroxyprostaglandin dehydrogenase [NAD+] monomer (EC 1.1.1.141; EC 1.1.1.232) from Homo sapiens (see 6 papers)
PGDH_HUMAN / P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; Eicosanoid/docosanoid dehydrogenase [NAD(+)]; Prostaglandin dehydrogenase 1; Short chain dehydrogenase/reductase family 36C member 1; EC 1.1.1.141; EC 1.1.1.-; EC 1.1.1.232 from Homo sapiens (Human) (see 13 papers)
P15428 15-hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141); 13,14-dehydro-15-oxoprostaglandin 13-reductase (EC 1.3.1.48) from Homo sapiens (see 11 papers)
    28% identity, 96% coverage of query (92.8 bits)

1zemA / Q8GR61 Crystal structure of NAD+-bound xylitol dehydrogenase (see paper)
    35% identity, 83% coverage of query (92.8 bits)

1gegE / Q48436 Cryatal structure analysis of meso-2,3-butanediol dehydrogenase (see paper)
    33% identity, 95% coverage of query (92.4 bits)

7krmC / A0A077GFB1 Putative fabg bound to nadh from acinetobacter baumannii
    33% identity, 98% coverage of query (92.4 bits)

5vt6A / Q3JJT1 Crystal structure of acetoacetyl-coa reductase from burkholderia pseudomallei 1710b complexed with NADP
    32% identity, 96% coverage of query (92.4 bits)

2d1yA Crystal structure of tt0321 from thermus thermophilus hb8
    34% identity, 96% coverage of query (91.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory